Lista de obras - Nils G Walter - Dominio Público Uruguay

A base change in the catalytic core of the hairpin ribozyme perturbs function but not domain docking

artículo científico publicado en 2001

A biosensor for theophylline based on fluorescence detection of ligand-induced hammerhead ribozyme cleavage.

artículo científico publicado en 2002

A bird's eye view tracking slow nanometer-scale movements of single molecular nano-assemblies

artículo científico publicado en 2010

A novel method to accurately locate and count large numbers of steps by photobleaching

artículo científico publicado en 2016

A rugged free energy landscape separates multiple functional RNA folds throughout denaturation

artículo científico publicado en 2008

Analysis of complex single-molecule FRET time trajectories

artículo científico publicado en 2010

Assay for glucosamine 6-phosphate using a ligand-activated ribozyme with fluorescence resonance energy transfer or CE-laser-induced fluorescence detection.

artículo científico publicado en 2008

Automatic classification and segmentation of single-molecule fluorescence time traces with deep learning

scientific article published on 17 November 2020

Beyond DNA origami: the unfolding prospects of nucleic acid nanotechnology ⬇️

artículo científico publicado el 30 de noviembre de 2011

Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing

artículo científico publicado en 2013

Biological Pathway Specificity in the Cell-Does Molecular Diversity Matter?

scientific article published on 27 June 2019

Biopolymers celebrates 50 years of nucleic acids research

artículo científico publicado en 2013

Catalytic core structure of the trans-acting HDV ribozyme is subtly influenced by sequence variation outside the core

scientific article published on 01 June 2006

Cations and hydration in catalytic RNA: molecular dynamics of the hepatitis delta virus ribozyme

artículo científico publicado en 2006

Chemical feasibility of the general acid/base mechanism of glmS ribozyme self-cleavage

artículo científico publicado en 2015

Chemical modification resolves the asymmetry of siRNA strand degradation in human blood serum

artículo científico publicado en 2007

Conformational dynamics of single pre-mRNA molecules during in vitro splicing

artículo científico publicado en 2010

Cooperative and directional folding of the preQ1 riboswitch aptamer domain

artículo científico publicado en 2011

Correlating structural dynamics and function in single ribozyme molecules

artículo científico publicado en 2002

DNA-cholesterol barges as programmable membrane-exploring agents

artículo científico publicado en 2014

Diffusely bound Mg2+ ions slightly reorient stems I and II of the hammerhead ribozyme to increase the probability of formation of the catalytic core

artículo científico publicado en 2003

Direct Kinetic Fingerprinting for High-Accuracy Single-Molecule Counting of Diverse Disease Biomarkers

artículo científico publicado en 2020

Direct kinetic fingerprinting and digital counting of single protein molecules

scientific article published on 31 August 2020

Discovering anomalous hybridization kinetics on DNA nanostructures using single-molecule fluorescence microscopy.

artículo científico publicado en 2014

Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver

artículo científico publicado en 2012

Dissecting non-coding RNA mechanisms in cellulo by Single-molecule High-Resolution Localization and Counting

artículo científico publicado en 2013

Dissecting the multistep reaction pathway of an RNA enzyme by single-molecule kinetic "fingerprinting".

artículo científico publicado en 2007

Do-it-yourself guide: how to use the modern single-molecule toolkit

artículo científico publicado en 2008

Dynamics inherent in helix 27 from Escherichia coli 16S ribosomal RNA.

artículo científico publicado en 2004

Editorial for "non-coding RNA methods".

artículo científico publicado en 2013

Electron Microscopic Visualization of Protein Assemblies on Flattened DNA Origami.

artículo científico publicado en 2015

Exploring the speed limit of toehold exchange with a cartwheeling DNA acrobat

artículo científico publicado en 2018

Extensive molecular dynamics simulations showing that canonical G8 and protonated A38H+ forms are most consistent with crystal structures of hairpin ribozyme

artículo científico publicado en 2010

Flexible casting of modular self-aligning microfluidic assembly blocks.

artículo científico publicado en 2011

Focus on function: single molecule RNA enzymology.

artículo científico publicado en 2007

Following the messenger: Recent innovations in live cell single molecule fluorescence imaging

scientific article published on 28 January 2020

From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond

artículo científico publicado en 2018

Future of biomedical sciences: single molecule microscopy.

artículo científico publicado en 2007

General base catalysis for cleavage by the active-site cytosine of the hepatitis delta virus ribozyme: QM/MM calculations establish chemical feasibility

artículo científico publicado en 2008

Global structure and flexibility of hairpin ribozymes with extended terminal helices

artículo científico publicado en 1999

Going viral: riding the RNA wave to discovery

artículo científico publicado en 2015

Hierarchical mechanism of amino acid sensing by the T-box riboswitch.

artículo científico publicado en 2018

High-resolution three-dimensional mapping of mRNA export through the nuclear pore

artículo científico publicado en 2013

Hyperosmotic phase separation: Condensates beyond inclusions, granules and organelles

artículo científico publicado en 2020

Impact of an extruded nucleotide on cleavage activity and dynamic catalytic core conformation of the hepatitis delta virus ribozyme.

artículo científico publicado en 2007

Intracellular single molecule microscopy reveals two kinetically distinct pathways for microRNA assembly ⬇️

artículo científico publicado el 12 de junio de 2012

Introduction to Single Molecule Imaging and Mechanics: Seeing and Touching Molecules One at a Time

scientific article published on 01 March 2014

Introductory editorial: Special section on single-molecule and super-resolution microscopy of biopolymers

artículo científico publicado en 2016

KRAS Engages AGO2 to Enhance Cellular Transformation

artículo científico

Kinetic fingerprinting to identify and count single nucleic acids

artículo científico publicado en 2015

Kinetics coming into focus: Single-molecule microscopy of riboswitch dynamics

scientific article published on 29 October 2018

Leakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme.

artículo científico publicado en 2008

Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World

artículo científico publicado en 2018

Local conformational changes in the catalytic core of the trans-acting hepatitis delta virus ribozyme accompany catalysis

artículo científico publicado en 2002

Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch

artículo científico publicado en 2019

Long-range impact of peripheral joining elements on structure and function of the hepatitis delta virus ribozyme

artículo científico publicado en 2007

Long-range tertiary interactions in single hammerhead ribozymes bias motional sampling toward catalytically active conformations

artículo científico publicado en 2010

Magnesium dependence of the amplified conformational switch in the trans-acting hepatitis delta virus ribozyme

artículo científico publicado en 2004

Meeting report: SMART timing--principles of single molecule techniques course at the University of Michigan 2014.

artículo científico publicado en 2015

Mg2+-induced compaction of single RNA molecules monitored by tethered particle microscopy

artículo científico publicado en 2006

Michaelis-Menten is dead, long live Michaelis-Menten!

scientific article published on 01 February 2006

Modelling viral evolution in vitro using exo- Klenow polymerase: continuous selection of strand displacement amplified DNA that binds an oligodeoxynucleotide to form a triple-helix

artículo científico publicado en 1995

Molecular dynamics and quantum mechanics of RNA: conformational and chemical change we can believe in

artículo científico publicado en 2010

Molecular dynamics simulations of RNA: an in silico single molecule approach.

artículo científico publicado en 2007

Molecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme.

artículo científico publicado en 2009

Molecular robots guided by prescriptive landscapes

artículo científico publicado en 2010

Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm

scientific article published on 25 May 2014

Multifactorial modulation of binding and dissociation kinetics on two-dimensional DNA nanostructures

artículo científico

Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

artículo científico publicado en 2016

Native purification and labeling of RNA for single molecule fluorescence studies

artículo científico publicado en 2015

Nondenaturing purification of co-transcriptionally folded RNA avoids common folding heterogeneity

artículo científico publicado en 2010

On-line polymerase chain reaction (PCR) monitoring

artículo científico publicado en 1998

Paclitaxel-conjugated PAMAM dendrimers adversely affect microtubule structure through two independent modes of action

artículo científico publicado en 2013

Probing RNA-protein interactions using pyrene-labeled oligodeoxynucleotides: Qbeta replicase efficiently binds small RNAs by recognizing pyrimidine residues

artículo científico publicado en 1997

Probing non-selective cation binding in the hairpin ribozyme with Tb(III).

artículo científico publicado en 2000

Program review. The Interdisciplinary Biophysics Graduate Program at the University of Michigan.

artículo científico publicado en 2008

Protein unties the pseudoknot: S1-mediated unfolding of RNA higher order structure

scientific article published on 01 February 2020

Protonation states of the key active site residues and structural dynamics of the glmS riboswitch as revealed by molecular dynamics

artículo científico publicado en 2010

Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2.

scientific article published on 19 June 2009

Putting Humpty-Dumpty Together: Clustering the Functional Dynamics of Single Biomolecular Machines Such as the Spliceosome

artículo científico publicado en 2016

Pyrrolo-C as a fluorescent probe for monitoring RNA secondary structure formation

artículo científico publicado en 2006

QM/MM studies of hairpin ribozyme self-cleavage suggest the feasibility of multiple competing reaction mechanisms

artículo científico publicado en 2011

RNA chaperones stimulate formation and yield of the U3 snoRNA-Pre-rRNA duplexes needed for eukaryotic ribosome biogenesis.

artículo científico publicado en 2009

RNA degradation in cell extracts: real-time monitoring by fluorescence resonance energy transfer

artículo científico publicado en 2003

RNA dynamics: it is about time.

artículo científico publicado en 2008

Rational design of DNA-actuated enzyme nanoreactors guided by single molecule analysis.

artículo científico publicado en 2016

Reaction pathway of the trans-acting hepatitis delta virus ribozyme: a conformational change accompanies catalysis

artículo científico publicado en 2002

Secondary structure of bacteriophage T4 gene 60 mRNA: implications for translational bypassing

artículo científico publicado en 2013

Significant kinetic solvent isotope effects in folding of the catalytic RNA from the hepatitis delta virus

artículo científico publicado en 2003

Single Molecule Cluster Analysis dissects splicing pathway conformational dynamics

artículo científico publicado en 2015

Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.

artículo científico publicado en 2008

Single molecule fluorescence approaches shed light on intracellular RNAs

artículo científico publicado en 2014

Single molecule fluorescence control for nanotechnology.

artículo científico publicado en 2005

Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure

artículo científico publicado en 2013

Single-Molecule Kinetic Fingerprinting for the Ultrasensitive Detection of Small Molecules with Aptasensors

artículo científico publicado en 2019

Single-Molecule Pull-Down FRET to Dissect the Mechanisms of Biomolecular Machines

artículo científico publicado en 2015

Single-molecule enzymology à la Michaelis-Menten

artículo científico publicado en 2014

Single-molecule tools for enzymology, structural biology, systems biology and nanotechnology: an update

artículo científico publicado en 2014

Solution probing of metal ion binding by helix 27 from Escherichia coli 16S rRNA.

artículo científico publicado en 2005

Solution structure of an alternate conformation of helix27 from Escherichia coli16S rRNA

artículo científico publicado en 2011

Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites

artículo científico publicado en 2016

Structural analysis of a class III preQ1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics

artículo científico publicado en 2015

Structural basis for heterogeneous kinetics: Reengineering the hairpin ribozyme ⬇️

artículo científico publicado el 26 de mayo de 1998

Structural basis for the guanosine requirement of the hairpin ribozyme

artículo científico publicado en 1999

Structural dynamics of catalytic RNA highlighted by fluorescence resonance energy transfer.

artículo científico publicado en 2001

Structural dynamics of precursor and product of the RNA enzyme from the hepatitis delta virus as revealed by molecular dynamics simulations

artículo científico publicado en 2005

Structural modeling of sequence specificity by an autoantibody against single-stranded DNA.

artículo científico publicado en 2007

Super-resolution fingerprinting detects chemical reactions and idiosyncrasies of single DNA pegboards.

artículo científico publicado en 2013

Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors

artículo científico publicado en 2018

Terbium-mediated footprinting probes a catalytic conformational switch in the antigenomic hepatitis delta virus ribozyme

artículo científico publicado en 2004

Tertiary structure formation in the hairpin ribozyme monitored by fluorescence resonance energy transfer ⬇️

artículo científico publicado el 15 de abril de 1998

The 5' leader of precursor tRNAAsp bound to the Bacillus subtilis RNase P holoenzyme has an extended conformation.

artículo científico publicado en 2005

The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts

artículo científico publicado en 2016

The Small Ribozymes: Common and Diverse Features Observed through the FRET Lens

artículo científico publicado en 2009

The blessing and curse of RNA dynamics: past, present, and future

artículo científico publicado en 2009

The hairpin ribozyme: structure, assembly and catalysis

artículo científico publicado en 1998

The hairpin ribozyme: structure, assembly and catalysis

The hammerhead, hairpin and VS ribozymes are catalytically proficient in monovalent cations alone

artículo científico publicado en 1998

The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling.

artículo científico publicado en 2015

The role of an active site Mg(2+) in HDV ribozyme self-cleavage: insights from QM/MM calculations.

artículo científico publicado en 2015

The solvent-protected core of the hairpin ribozyme-substrate complex

artículo científico publicado en 1998

Theoretical studies of RNA catalysis: hybrid QM/MM methods and their comparison with MD and QM.

scientific article published on 04 May 2009

Trans-acting glmS catalytic riboswitch: locked and loaded

artículo científico publicado en 2007

Trans-acting hepatitis delta virus ribozyme: catalytic core and global structure are dependent on the 5' substrate sequence

artículo científico publicado en 2003

Tuning RNA folding and function through rational design of junction topology

artículo científico publicado en 2017

Ultraspecific and Amplification-Free Quantification of Mutant DNA by Single-Molecule Kinetic Fingerprinting

scientific article published on 05 September 2018

Under the microscope: single molecule symposium at the University of Michigan, 2006

artículo científico publicado en 2007

Unraveling the structural complexity in a single-stranded RNA tail: implications for efficient ligand binding in the prequeuosine riboswitch.

artículo científico publicado en 2011

Versatile transcription control based on reversible dCas9 binding

scientific article published on 18 July 2019

Wobble pairs of the HDV ribozyme play specific roles in stabilization of active site dynamics

artículo científico publicado en 2015

siRNA-Like Double-Stranded RNAs Are Specifically Protected Against Degradation in Human Cell Extract ⬇️

artículo científico publicado el 27 de mayo de 2011

Lista de obras de Nils G Walter

A base change in the catalytic core of the hairpin ribozyme perturbs function but not domain docking

A biosensor for theophylline based on fluorescence detection of ligand-induced hammerhead ribozyme cleavage.

A bird's eye view tracking slow nanometer-scale movements of single molecular nano-assemblies

A novel method to accurately locate and count large numbers of steps by photobleaching

A rugged free energy landscape separates multiple functional RNA folds throughout denaturation

Analysis of complex single-molecule FRET time trajectories

Assay for glucosamine 6-phosphate using a ligand-activated ribozyme with fluorescence resonance energy transfer or CE-laser-induced fluorescence detection.

Automatic classification and segmentation of single-molecule fluorescence time traces with deep learning

Beyond DNA origami: the unfolding prospects of nucleic acid nanotechnology ⬇️

Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing

Biological Pathway Specificity in the Cell-Does Molecular Diversity Matter?

Biopolymers celebrates 50 years of nucleic acids research

Catalytic core structure of the trans-acting HDV ribozyme is subtly influenced by sequence variation outside the core

Cations and hydration in catalytic RNA: molecular dynamics of the hepatitis delta virus ribozyme

Chemical feasibility of the general acid/base mechanism of glmS ribozyme self-cleavage

Chemical modification resolves the asymmetry of siRNA strand degradation in human blood serum

Conformational dynamics of single pre-mRNA molecules during in vitro splicing

Cooperative and directional folding of the preQ1 riboswitch aptamer domain

Correlating structural dynamics and function in single ribozyme molecules

DNA-cholesterol barges as programmable membrane-exploring agents

Diffusely bound Mg2+ ions slightly reorient stems I and II of the hammerhead ribozyme to increase the probability of formation of the catalytic core

Direct Kinetic Fingerprinting for High-Accuracy Single-Molecule Counting of Diverse Disease Biomarkers

Direct kinetic fingerprinting and digital counting of single protein molecules

Discovering anomalous hybridization kinetics on DNA nanostructures using single-molecule fluorescence microscopy.

Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver

Dissecting non-coding RNA mechanisms in cellulo by Single-molecule High-Resolution Localization and Counting

Dissecting the multistep reaction pathway of an RNA enzyme by single-molecule kinetic "fingerprinting".

Do-it-yourself guide: how to use the modern single-molecule toolkit

Dynamics inherent in helix 27 from Escherichia coli 16S ribosomal RNA.

Editorial for "non-coding RNA methods".

Electron Microscopic Visualization of Protein Assemblies on Flattened DNA Origami.

Exploring the speed limit of toehold exchange with a cartwheeling DNA acrobat

Extensive molecular dynamics simulations showing that canonical G8 and protonated A38H+ forms are most consistent with crystal structures of hairpin ribozyme

Flexible casting of modular self-aligning microfluidic assembly blocks.

Focus on function: single molecule RNA enzymology.

Following the messenger: Recent innovations in live cell single molecule fluorescence imaging

From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond

Future of biomedical sciences: single molecule microscopy.

General base catalysis for cleavage by the active-site cytosine of the hepatitis delta virus ribozyme: QM/MM calculations establish chemical feasibility

Global structure and flexibility of hairpin ribozymes with extended terminal helices

Going viral: riding the RNA wave to discovery

Hierarchical mechanism of amino acid sensing by the T-box riboswitch.

High-resolution three-dimensional mapping of mRNA export through the nuclear pore

Hyperosmotic phase separation: Condensates beyond inclusions, granules and organelles

Impact of an extruded nucleotide on cleavage activity and dynamic catalytic core conformation of the hepatitis delta virus ribozyme.

Intracellular single molecule microscopy reveals two kinetically distinct pathways for microRNA assembly ⬇️

Introduction to Single Molecule Imaging and Mechanics: Seeing and Touching Molecules One at a Time

Introductory editorial: Special section on single-molecule and super-resolution microscopy of biopolymers

KRAS Engages AGO2 to Enhance Cellular Transformation

Kinetic fingerprinting to identify and count single nucleic acids

Kinetics coming into focus: Single-molecule microscopy of riboswitch dynamics

Leakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme.

Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World

Local conformational changes in the catalytic core of the trans-acting hepatitis delta virus ribozyme accompany catalysis

Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch

Long-range impact of peripheral joining elements on structure and function of the hepatitis delta virus ribozyme

Long-range tertiary interactions in single hammerhead ribozymes bias motional sampling toward catalytically active conformations

Magnesium dependence of the amplified conformational switch in the trans-acting hepatitis delta virus ribozyme

Meeting report: SMART timing--principles of single molecule techniques course at the University of Michigan 2014.

Mg2+-induced compaction of single RNA molecules monitored by tethered particle microscopy

Michaelis-Menten is dead, long live Michaelis-Menten!

Modelling viral evolution in vitro using exo- Klenow polymerase: continuous selection of strand displacement amplified DNA that binds an oligodeoxynucleotide to form a triple-helix

Molecular dynamics and quantum mechanics of RNA: conformational and chemical change we can believe in

Molecular dynamics simulations of RNA: an in silico single molecule approach.

Molecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme.

Molecular robots guided by prescriptive landscapes

Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm

Multifactorial modulation of binding and dissociation kinetics on two-dimensional DNA nanostructures

Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

Native purification and labeling of RNA for single molecule fluorescence studies

Nondenaturing purification of co-transcriptionally folded RNA avoids common folding heterogeneity

On-line polymerase chain reaction (PCR) monitoring

Paclitaxel-conjugated PAMAM dendrimers adversely affect microtubule structure through two independent modes of action

Probing RNA-protein interactions using pyrene-labeled oligodeoxynucleotides: Qbeta replicase efficiently binds small RNAs by recognizing pyrimidine residues

Probing non-selective cation binding in the hairpin ribozyme with Tb(III).

Program review. The Interdisciplinary Biophysics Graduate Program at the University of Michigan.

Protein unties the pseudoknot: S1-mediated unfolding of RNA higher order structure

Protonation states of the key active site residues and structural dynamics of the glmS riboswitch as revealed by molecular dynamics

Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2.