Lista de obras - Kristen J. Brennand - Dominio Público Uruguay

A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles

artículo científico publicado en 2020

A guide to generating and using hiPSC derived NPCs for the study of neurological diseases

artículo científico publicado en 2015

A new recipe for serotonergic neurons

article published in 2015

A psychiatric disease-related circular RNA controls synaptic gene expression and cognition

scientific article published on 27 January 2020

A role for noncoding variation in schizophrenia

artículo científico publicado en 2014

ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs

artículo científico publicado en 2020

All beta cells contribute equally to islet growth and maintenance

artículo científico publicado en 2007

Altered WNT Signaling in Human Induced Pluripotent Stem Cell Neural Progenitor Cells Derived from Four Schizophrenia Patients

artículo científico publicado en 2015

Altered proliferation and networks in neural cells derived from idiopathic autistic individuals

artículo científico publicado en 2016

Application of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease

artículo científico publicado en 2017

Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

artículo científico publicado en 2018

Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines

artículo científico publicado en 2011

CRISPR-based functional evaluation of schizophrenia risk variants

scientific article published on 02 July 2019

Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1.

artículo científico publicado en 2017

Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells.

artículo científico publicado en 2015

Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia

artículo científico publicado en 2022

Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder

scientific article published on 16 November 2018

Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection

artículo científico publicado en 2020

Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia

artículo científico publicado en 2011

Correction: All ß Cells Contribute Equally to Islet Growth and Maintenance.

artículo científico publicado en 2007

Correction: Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

scientific article published on 06 January 2020

Cracking the bell jar

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

artículo científico publicado en 2015

Detecting mutant huntingtin protein in HD patients

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

artículo científico publicado en 2015

Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

scientific article published on 21 August 2019

Dopaminergic differentiation of schizophrenia hiPSCs

artículo científico publicado en 2015

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

artículo científico publicado en 2016

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

scientific article published in Nature

Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders

artículo científico publicado en 2014

Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs

artículo científico publicado en 2019

Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

artículo científico publicado en 2018

Functional annotation of rare structural variation in the human brain

artículo científico publicado en 2020

Gene expression elucidates functional impact of polygenic risk for schizophrenia

artículo científico publicado en 2016

High-efficient generation of induced pluripotent stem cells from human astrocytes

artículo científico publicado en 2010

Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons

artículo científico publicado en 2014

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

artículo científico publicado en 2016

If there is not one cure for schizophrenia, there may be many

artículo científico publicado en 2020

Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.

artículo científico publicado en 2015

Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises

artículo científico publicado en 2011

Inducing cellular aging: enabling neurodegeneration-in-a-dish

artículo científico publicado en 2013

Inheritance of fear and trauma

article by Kristen J. Brennand published 26 August 2015 in Science Translational Medicine

Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.

artículo científico publicado en 2016

Insights into the pharmacology of depression

scholarly article by Kristen J. Brennand published 7 October 2015 in Science Translational Medicine

Integrating CRISPR Engineering and hiPSC-Derived 2D Disease Modeling Systems

artículo científico publicado en 2020

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease

artículo científico publicado en 2016

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

artículo científico publicado en 2011

MODELING PREDISPOSITION TO SZ USING HIPSCS

artículo científico publicado en 2014

Mapping regulatory variants in hiPSC models.

artículo científico publicado en 2018

Massively parallel techniques for cataloguing the regulome of the human brain

artículo científico publicado en 2020

Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells.

artículo científico publicado en 2014

Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cells

artículo científico publicado en 2013

Modeling hippocampal neurogenesis using human pluripotent stem cells

artículo científico

Modeling predisposition to schizophrenia using hiPSCs

Modeling psychiatric disorders at the cellular and network levels

artículo científico publicado en 2012

Modeling psychiatric disorders through reprogramming

artículo científico publicado en 2011

Modeling schizophrenia using induced pluripotent stem cell-derived and fibroblast-induced neurons

artículo científico publicado en 2012

Modeling the complex genetic architectures of brain disease

artículo científico publicado en 2020

Modelling schizophrenia using human induced pluripotent stem cells

artículo científico publicado en 2011

Mosaic copy number variation in human neurons

artículo científico publicado en 2013

Neural Induction of Embryonic Stem/Induced Pluripotent Stem Cells

Neural organoids for disease phenotyping, drug screening and developmental biology studies

artículo científico publicado en 2016

Neural stem and progenitor cells in health and disease

artículo científico

Neuronal impact of patient-specific aberrant NRXN1α splicing

scientific article published on 29 November 2019

New considerations for hiPSC-based models of neuropsychiatric disorders

artículo científico publicado en 2018

Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease

artículo científico publicado en 2015

Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics

artículo científico publicado en 2008

Patient-derived hiPSC neurons with heterozygous CNTNAP2 deletions display altered neuronal gene expression and network activity

artículo científico publicado en 2017

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

artículo científico publicado en 2014

Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells

artículo científico publicado en 2015

Rapid cellular turnover in adipose tissue

artículo científico publicado en 2011

Reprogramming of pancreatic beta cells into induced pluripotent stem cells

artículo científico publicado en 2008

Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders.

artículo científico publicado en 2014

Slow and steady is the key to beta-cell replication

artículo científico publicado en 2009

Spatial genome exploration in the context of cognitive and neurological disease

artículo científico publicado en 2019

Spatial genome organization and cognition

artículo científico publicado en 2016

Stem cells in gels

Synergistic effects of common schizophrenia risk variants

scientific article published on 23 September 2019

THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders

artículo científico publicado en 2018

The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample

artículo científico publicado en 2016

The functional and evolutionary impacts of human-specific deletions in conserved elements ⬇️

Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan-McDermid syndrome and autism

scientific article published on 19 June 2020

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.

artículo científico publicado en 2017

Using hiPSCs to model neuropsychiatric copy number variations (CNVs) has potential to reveal underlying disease mechanisms

artículo científico publicado en 2015

What if it was easier to prevent schizophrenia than to treat it?

artículo científico publicado en 2017

Lista de obras de Kristen J. Brennand

A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles

A guide to generating and using hiPSC derived NPCs for the study of neurological diseases

A new recipe for serotonergic neurons

A psychiatric disease-related circular RNA controls synaptic gene expression and cognition

A role for noncoding variation in schizophrenia

ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs

All beta cells contribute equally to islet growth and maintenance

Altered WNT Signaling in Human Induced Pluripotent Stem Cell Neural Progenitor Cells Derived from Four Schizophrenia Patients

Altered proliferation and networks in neural cells derived from idiopathic autistic individuals

Application of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease

Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines

CRISPR-based functional evaluation of schizophrenia risk variants

Cerebral organoids reveal early cortical maldevelopment in schizophrenia—computational anatomy and genomics, role of FGFR1.

Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells.

Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia

Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder

Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection

Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia

Correction: All ß Cells Contribute Equally to Islet Growth and Maintenance.

Correction: Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

Cracking the bell jar

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

Detecting mutant huntingtin protein in HD patients

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

Dopaminergic differentiation of schizophrenia hiPSCs

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders

Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs

Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

Functional annotation of rare structural variation in the human brain

Gene expression elucidates functional impact of polygenic risk for schizophrenia

High-efficient generation of induced pluripotent stem cells from human astrocytes

Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

If there is not one cure for schizophrenia, there may be many

Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.

Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises

Inducing cellular aging: enabling neurodegeneration-in-a-dish

Inheritance of fear and trauma

Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.

Insights into the pharmacology of depression

Integrating CRISPR Engineering and hiPSC-Derived 2D Disease Modeling Systems

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

MODELING PREDISPOSITION TO SZ USING HIPSCS

Mapping regulatory variants in hiPSC models.

Massively parallel techniques for cataloguing the regulome of the human brain

Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells.

Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cells

Modeling hippocampal neurogenesis using human pluripotent stem cells

Modeling predisposition to schizophrenia using hiPSCs

Modeling psychiatric disorders at the cellular and network levels

Modeling psychiatric disorders through reprogramming

Modeling schizophrenia using induced pluripotent stem cell-derived and fibroblast-induced neurons

Modeling the complex genetic architectures of brain disease

Modelling schizophrenia using human induced pluripotent stem cells

Mosaic copy number variation in human neurons

Neural Induction of Embryonic Stem/Induced Pluripotent Stem Cells

Neural organoids for disease phenotyping, drug screening and developmental biology studies

Neural stem and progenitor cells in health and disease

Neuronal impact of patient-specific aberrant NRXN1α splicing

New considerations for hiPSC-based models of neuropsychiatric disorders

Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease

Normal ovarian surface epithelial label-retaining cells exhibit stem/progenitor cell characteristics

Patient-derived hiPSC neurons with heterozygous CNTNAP2 deletions display altered neuronal gene expression and network activity

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells

Rapid cellular turnover in adipose tissue

Reprogramming of pancreatic beta cells into induced pluripotent stem cells

Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders.

Slow and steady is the key to beta-cell replication

Spatial genome exploration in the context of cognitive and neurological disease

Spatial genome organization and cognition

Stem cells in gels

Synergistic effects of common schizophrenia risk variants

THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders