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Lista de obras de James E. Crowe Jr.

2593. Human Monoclonal Antibodies Potently Neutralize Enterovirus D68 in both a Clade-Specific and -Independent Manner

A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses

artículo científico publicado en 2016

A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV

artículo científico publicado en 2016

A RhoA-derived peptide inhibits syncytium formation induced by respiratory syncytial virus and parainfluenza virus type 3.

artículo científico publicado en 2000

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

scientific article published on 01 August 2018

A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface

scientific article published on 01 May 2019

A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin

artículo científico publicado en 2011

A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase

artículo científico publicado en 2012

A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction

artículo científico publicado en 2009

A cold-passaged, attenuated strain of human respiratory syncytial virus contains mutations in the F and L genes

artículo científico publicado en 1995

A comparison in chimpanzees of the immunogenicity and efficacy of live attenuated respiratory syncytial virus (RSV) temperature-sensitive mutant vaccines and vaccinia virus recombinants that express the surface glycoproteins of RSV.

artículo científico publicado en 1993

A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles

artículo científico publicado en 2012

A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice

scientific article published on 06 August 2020

A further attenuated derivative of a cold-passaged temperature-sensitive mutant of human respiratory syncytial virus retains immunogenicity and protective efficacy against wild-type challenge in seronegative chimpanzees

artículo científico publicado en 1994

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

artículo científico publicado en 2015

A human antibody against Zika virus crosslinks the E protein to prevent infection

artículo científico publicado en 2017

A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection

scientific article published on 01 May 2019

A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.

artículo científico publicado en 2018

A new quaternary structure epitope on dengue virus serotype 2 is the target of durable type-specific neutralizing antibodies

artículo científico publicado en 2015

A novel pre-fusion conformation-specific neutralizing epitope on the respiratory syncytial virus fusion protein

artículo científico publicado en 2017

A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface

artículo científico publicado en 2014

A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections

artículo científico publicado en 2005

A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions

artículo científico publicado en 2018

A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo

artículo científico publicado en 2007

A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin

artículo científico publicado en 2013

A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis

artículo científico publicado en 2012

Acquisition of the ts phenotype by a chemically mutagenized cold-passaged human respiratory syncytial virus vaccine candidate results from the acquisition of a single mutation in the polymerase (L) gene

artículo científico publicado en 1996

Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication

artículo científico publicado en 2011

Adverse events after smallpox immunizations are associated with alterations in systemic cytokine levels

artículo científico publicado en 2004

Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia

artículo científico publicado en 2008

An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody

artículo científico publicado en 2011

An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats

artículo científico publicado en 2008

An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies

artículo científico publicado en 2008

An update on approaches to the development of respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) vaccines

artículo científico publicado en 1994

Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

artículo científico publicado en 2020

Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface

artículo científico publicado en 2020

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy

artículo científico publicado en 2020

Antibody Determinants of Influenza Immunity

scientific article published on 01 April 2019

Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site

artículo científico publicado en 2013

Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors

scientific article published on 01 August 2018

Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA

artículo científico publicado en 2014

Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors

artículo científico publicado en 2018

Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine

artículo científico publicado en 2019

Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells

artículo científico publicado en 2003

Application of semiconductor fluorescent nanocrystals as optical probes for rapid early viral detection

Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein

artículo científico publicado en 2015

Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap

artículo científico publicado en 2018

B-Cell Development

article

Broad dengue neutralization in mosquitoes expressing an engineered antibody

scientific article published on 16 January 2020

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress

artículo científico publicado en 2015

Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Virus E1E2

artículo científico publicado en 2019

Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection

scholarly article published by Pamela J. Bjorkman in 2018

Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region

artículo científico publicado en 2018

Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance

artículo científico publicado en 2017

CD154 regulates primate humoral immunity to influenza

artículo científico publicado en 2003

CD40-ligand in primate cardiac allograft and viral immunity

artículo científico publicado en 2001

Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis

artículo científico publicado en 2009

Cellular immune responses to diluted and undiluted aventis pasteur smallpox vaccine

artículo científico publicado en 2006

Challenges and opportunities in developing respiratory syncytial virus therapeutics

artículo científico publicado en 2015

Characterization of dengue virus 2 growth in megakaryocyte-erythrocyte progenitor cells

artículo científico publicado en 2016

Characterization of recombinant yellow fever-dengue vaccine viruses with human monoclonal antibodies targeting key conformational epitopes

artículo científico publicado en 2018

Chimeric Filoviruses for Identification and Characterization of Monoclonal Antibodies

artículo científico publicado en 2016

Cold-passaged, temperature-sensitive mutants of human respiratory syncytial virus (RSV) are highly attenuated, immunogenic, and protective in seronegative chimpanzees, even when RSV antibodies are infused shortly before immunization

artículo científico publicado en 1995

Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells ⬇️

artículo científico publicado en 2013

Committing the Oldest Sins in the Newest Kind of Ways-Antibodies Targeting the Influenza Virus Type A Hemagglutinin Globular Head

artículo científico

Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

scientific article published on 10 September 2020

Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals

artículo científico publicado en 2022

Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants

artículo científico publicado en 2020

Cooperativity of actin and microtubule elements during replication of respiratory syncytial virus

artículo científico publicado en 2005

Coronavirus infection and hospitalizations for acute respiratory illness in young children

artículo científico publicado en 2009

Correction: Broad dengue neutralization in mosquitoes expressing an engineered antibody

artículo científico publicado en 2020

Correction: Tissue-Specific Expressed Antibody Variable Gene Repertoires

scientific article published on 24 January 2020

Corrigendum: Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

artículo científico publicado en 2012

Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections

artículo científico publicado en 2016

Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

artículo científico publicado en 2016

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

artículo científico publicado en 2020

Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

artículo científico publicado en 2019

Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity

artículo científico publicado en 2015

Current Understanding of Humoral Immunity to Enterovirus D68

scientific article published on 01 December 2018

Current approaches to the development of vaccines against disease caused by respiratory syncytial virus (RSV) and parainfluenza virus (PIV). A meeting report of the WHO Programme for Vaccine Development

artículo científico publicado en 1995

Cytokine expression patterns associated with systemic adverse events following smallpox immunization

artículo científico publicado en 2006

DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers

artículo científico publicado en 2015

Deciphering the human immunome

Deep sequencing and human antibody repertoire analysis

artículo científico publicado en 2016

Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing Properties Recognize a Single Immunodominant Antigenic Site

artículo científico publicado en 2015

Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice

artículo científico publicado en 2019

Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity

artículo científico publicado en 2014

Dengue viruses are enhanced by distinct populations of serotype cross-reactive antibodies in human immune sera

artículo científico publicado en 2014

Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences

artículo científico publicado en 2015

Detection of viral infections using colloidal quantum dots

Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6.

artículo científico publicado en 2016

Development of Human Monoclonal Antibodies Against Respiratory Syncytial Virus Using a High Efficiency Human Hybridoma Technique

artículo científico publicado en 2016

Diagnostic errors in interpretation of pediatric musculoskeletal radiographs at common injury sites.

artículo científico publicado en 2014

Differential accessibility of a rotavirus VP6 epitope in trimers comprising type I, II, or III channels as revealed by binding of a human rotavirus VP6-specific antibody

artículo científico

Differential regulation of granzyme and perforin in effector and memory T cells following smallpox immunization

artículo científico publicado en 2005

Discovering naturally processed antigenic determinants that confer protective T cell immunity

artículo científico publicado en 2013

Discovery of Marburg virus neutralizing antibodies from virus-naïve human antibody repertoires using large-scale structural predictions

scientific article published on 23 November 2020

Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis

artículo científico publicado en 2020

E. coli production process yields stable dengue 1 virus-sized particles (VSPs)

artículo científico publicado en 2020

Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection

scholarly article by Lauren E Williamson et al published 15 April 2019 in Journal of Virology

Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation

artículo científico publicado en 2016

Ebola vaccine–induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects

scientific article published in 2021

Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies

scholarly article by Philipp A Ilinykh et al published 22 November 2018 in Journal of Infectious Diseases

Effect of zinc salts on respiratory syncytial virus replication

artículo científico publicado en 2004

Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates

scholarly article by Pavlo Gilchuk et al published 22 November 2018 in Journal of Infectious Diseases

Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization

scientific article published on 18 November 2019

Emerging studies of human HIV-specific antibody repertoires

artículo científico publicado en 2010

Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1

artículo científico publicado en 2016

Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope

artículo científico publicado en 2008

Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface.

artículo científico publicado en 2017

Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence

artículo científico publicado en 2011

Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein

artículo científico publicado en 2014

Evaluation of Two Live, Cold‐Passaged, Temperature‐Sensitive Respiratory Syncytial Virus Vaccines in Chimpanzees and in Human Adults, Infants, and Children ⬇️

artículo científico publicado el 1 de diciembre de 1997

Evaluation of a live, cold-passaged, temperature-sensitive, respiratory syncytial virus vaccine candidate in infancy

artículo científico publicado en 2000

Evaporative cooling feature selection for genotypic data involving interactions

artículo científico publicado en 2007

Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells

artículo científico publicado en 2006

Examination of a fusogenic hexameric core from human metapneumovirus and identification of a potent synthetic peptide inhibitor from the heptad repeat 1 region

artículo científico publicado en 2006

Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19

artículo científico publicado en 2020

Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein

artículo científico publicado en 2003

Feature Selection using a Random Forests Classifier for the Integrated Analysis of Multiple Data Types

Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire

artículo científico publicado en 2012

Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding

artículo científico publicado en 2016

Functional Maturation of the Human Antibody Response to Rotavirus

article

Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1.

artículo científico publicado en 2016

Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles

artículo científico publicado en 2003

Genetic Predisposition for Adverse Events after Vaccination

article by James E. Crowe, Jr. published 15 July 2007 in Journal of Infectious Diseases

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

artículo científico publicado en 2021

Genetic and structural determinants of virus neutralizing antibodies.

artículo científico publicado en 2001

Genetic basis for adverse events after smallpox vaccination

artículo científico publicado en 2008

Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years

artículo científico publicado en 2009

Gold nanorod vaccine for respiratory syncytial virus

artículo científico publicado en 2013

H7N9 influenza virus neutralizing antibodies that possess few somatic mutations

artículo científico publicado en 2016

HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design

scientific article published on 01 November 2018

High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires

scientific article published on 01 July 2020

High frequency of shared clonotypes in human B cell receptor repertoires

artículo científico publicado en 2019

High-throughput antibody sequencing reveals genetic evidence of global regulation of the naïve and memory repertoires that extends across individuals

artículo científico publicado en 2012

Homing in on acute graft vs. host disease: tissue-specific T regulatory and Th17 cells

scientific article published on January 2010

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

artículo científico publicado en 2016

Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein

artículo científico publicado en 2016

Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses

scientific article published on 28 August 2018

Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection

artículo científico publicado en 2021

Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore

artículo científico publicado en 2013

Human VH1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis

artículo científico publicado en 2019

Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease

artículo científico publicado en 2020

Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses

artículo científico publicado en 2013

Human antibodies that neutralize respiratory droplet transmissible H5N1influenza viruses.

artículo científico publicado en 2013

Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins.

artículo científico publicado en 2018

Human germline antibody gene segments encode polyspecific antibodies

artículo científico publicado en 2013

Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site

artículo científico publicado en 2020

Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking and Fc-Mediated Mechanisms

scientific article published on 01 April 2019

Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children

artículo científico publicado en 2004

Human metapneumovirus as a major cause of human respiratory tract disease

artículo científico publicado en 2004

Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats

artículo científico publicado en 2006

Human metapneumovirus infection in children hospitalized for wheezing

artículo científico publicado en 2005

Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults

artículo científico publicado en 2005

Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation

artículo científico publicado en 2008

Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity ⬇️

artículo científico publicado el 1 de noviembre de 1992

Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease

scientific article published on 04 May 2020

Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics

artículo científico publicado en 2013

Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses

artículo científico publicado en 2012

Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions and monocytes for optimal therapeutic protection

artículo científico publicado en 2020

Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes

artículo científico publicado en 2012

Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS

artículo científico publicado en 2012

Human-likeness of antibody biologics determined by back-translation and comparison with large antibody variable gene repertoires

scientific article published on 01 January 2020

Humoral Immunity to Hantavirus Infection ⬇️

artículo científico publicado en 2020

Hybrid grammar-based approach to nonlinear dynamical system identification from biological time series

artículo científico publicado en 2006

Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring

scientific article published on 06 August 2020

Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein

artículo científico publicado en 2003

Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus

artículo científico publicado en 2005

Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

artículo científico publicado en 2012

Identification of potential human respiratory syncytial virus and metapneumovirus T cell epitopes using computational prediction and MHC binding assays

artículo científico publicado en 2011

Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis

artículo científico publicado en 2014

Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures

scientific article published on 04 December 2019

Immune responses of infants to infection with respiratory viruses and live attenuated respiratory virus candidate vaccines ⬇️

artículo científico publicado el 1 de agosto de 1998

Immunodominance of the VH1-46 Antibody Gene Segment in the Primary Repertoire of Human Rotavirus-Specific B Cells Is Reduced in the Memory Compartment through Somatic Mutation of Nondominant Clones

article

Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primates

artículo científico publicado en 2016

Immunology of viral respiratory tract infection in infancy

artículo científico publicado en 2003

Immunology. Crowdsourcing immunity

artículo científico publicado en 2013

Impact of new sequencing technologies on studies of the human B cell repertoire

artículo científico publicado en 2013

Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based Restraints

artículo científico publicado en 2016

In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model

scientific article published on 01 November 2018

Inappropriate Citation of Vaccine Article

scientific article published on 03 June 2019

Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth

scientific article published in PLoS ONE

Independent structural domains in paramyxovirus polymerase protein

artículo científico publicado en 2012

Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires

artículo científico publicado en 2003

Influence of maternal antibodies on neonatal immunization against respiratory viruses.

artículo científico publicado en 2001

Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice

artículo científico publicado en 2019

Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses

artículo científico publicado en 2012

Influenza Virus Resistance to Human Neutralizing Antibodies ⬇️

artículo científico publicado el 31 de julio de 2012

Influenza Virus-Specific Human Antibody Repertoire Studies

Influenza viruses with receptor-binding N1 neuraminidases occur sporadically in several lineages and show no attenuation in cell culture or mice.

artículo científico publicado en 2015

Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics

artículo científico publicado en 2020

Integrated technology platform for accelerated discovery of antiviral antibody therapeutics

artículo científico publicado en 2020

Integrating linear optimization with structural modeling to increase HIV neutralization breadth.

artículo científico publicado en 2018

Intracellular neutralization of a virus using a cell-penetrating molecular transporter

artículo científico publicado en 2013

Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection

artículo científico publicado en 2020

Introduction

Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Potential for a Universal Influenza Vaccine

artículo científico publicado en 2017

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus

artículo científico publicado en 2015

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus

artículo científico publicado en 2015

Isolation and characterization of a highly attenuated respiratory syncytial virus (RSV) vaccine candidate by mutagenesis of the incompletely attenuated RSV A2 ts-1 NG-1 mutant virus

artículo científico publicado en 1995

Isolation of a Second Recombinant Human Respiratory Syncytial Virus Monoclonal Antibody Fragment (Fab RSVF2–5) that Exhibits Therapeutic Efficacy In Vivo ⬇️

artículo científico publicado el 1 de abril de 1998

Isolation of dengue virus-specific memory B cells with live virus antigen from human subjects following natural infection reveals the presence of diverse novel functional groups of antibody clones

artículo científico publicado en 2014

Live subgroup B respiratory syncytial virus vaccines that are attenuated, genetically stable, and immunogenic in rodents and nonhuman primates

artículo científico publicado en 1996

Location and length distribution of somatic hypermutation-associated DNA insertions and deletions reveals regions of antibody structural plasticity

artículo científico publicado en 2012

Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization

artículo científico publicado en 2016

Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells

artículo científico publicado en 2006

Low frequency of broadly neutralizing HIV antibodies during chronic infection even in quaternary epitope targeting antibodies containing large numbers of somatic mutations

artículo científico

Machine learning competition in immunology - Prediction of HLA class I binding peptides.

artículo científico publicado en 2011

Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to DENV4 Infection and Vaccination

artículo científico publicado en 2016

Maturation-induced cloaking of neutralization epitopes on HIV-1 particles

artículo científico publicado en 2011

Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody

artículo científico publicado en 2018

Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge

scientific article published on 01 February 2020

Mechanism of human antibody-mediated neutralization of Marburg virus

artículo científico publicado en 2015

Molecular mechanisms driving respiratory syncytial virus assembly

artículo científico

Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action

artículo científico publicado en 2017

Monoclonal antibody-resistant mutants selected with a respiratory syncytial virus-neutralizing human antibody fab fragment (Fab 19) define a unique epitope on the fusion (F) glycoprotein

artículo científico publicado en 1998

Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus

artículo científico publicado en 2018

Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells

artículo científico publicado en 2019

Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.

artículo científico publicado en 2018

Multi-state design of flexible proteins predicts sequences optimal for conformational change

artículo científico publicado en 2020

Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein

artículo científico publicado en 2018

Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses

article published in the Proceedings of the National Academy of Sciences of the United States of America

Mxra8 is a receptor for multiple arthritogenic alphaviruses

artículo científico publicado en 2018

Natural evolution of a human virus-specific antibody gene repertoire by somatic hypermutation requires both hotspot-directed and randomly-directed processes

artículo científico publicado en 2005

Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses.

artículo científico publicado en 2009

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.

artículo científico publicado en 2008

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

artículo científico publicado en 2016

New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications

artículo científico publicado en 2019

Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

artículo científico publicado en 2020

Nucleotide sequence analysis of the respiratory syncytial virus subgroup A cold-passaged (cp) temperature sensitive (ts) cpts-248/404 live attenuated virus vaccine candidate

artículo científico publicado en 1996

Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors

artículo científico publicado en 2018

Paramyxoviruses: Respiratory Syncytial Virus and Human Metapneumovirus

Passive IgA monoclonal antibody is no more effective than IgG at protecting mice from mucosal challenge with respiratory syncytial virus

artículo científico publicado en 1999

Passively acquired antibodies suppress humoral but not cell-mediated immunity in mice immunized with live attenuated respiratory syncytial virus vaccines

artículo científico publicado en 2001

Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence

artículo científico publicado en 2016

Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection

artículo científico publicado en 2011

Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases

artículo científico publicado en 2016

Plasma deconvolution identifies broadly neutralizing antibodies associated with hepatitis C virus clearance

scientific article published on 13 August 2019

Pneumocystis carinii pneumonia in a girl with a midbrain glioma

artículo científico publicado en 2002

Population-based incidence of human metapneumovirus infection among hospitalized children

artículo científico publicado en 2010

Potent Neutralizing Human Monoclonal Antibodies Preferentially Target Mature Dengue Virus Particles: Implication for Novel Strategy for Dengue Vaccine

scholarly article by Wen-Yang Tsai et al published 1 December 2018 in Journal of Virology

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor binding head domains

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains

artículo científico publicado en 2019

Potently neutralizing and protective human antibodies against SARS-CoV-2

artículo científico publicado en 2020

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

artículo científico publicado en 2020

Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity

artículo científico publicado en 2012

Prevalence of Reovirus‐Specific Antibodies in Young Children in Nashville, Tennessee

article

Prevention of Fetal and Early Life Infections Through Maternal–Neonatal Immunization

Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design

artículo científico publicado en 2017

Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans

artículo científico publicado en 2017

Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes

artículo científico publicado en 2005

Proof of principle for epitope-focused vaccine design

artículo científico publicado en 2014

Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model

scientific article published on 08 February 2013

Prospective study of the incidence, clinical features, and outcome of symptomatic upper and lower respiratory tract infections by respiratory viruses in adult recipients of hematopoietic stem cell transplants for hematologic malignancies

artículo científico publicado en 2005

Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein

artículo científico publicado en 2018

Pseudovirion particle production by live poxvirus human immunodeficiency virus vaccine vector enhances humoral and cellular immune responses

artículo científico publicado en 2005

Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV.

artículo científico publicado en 2010

PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST

artículo científico publicado en 2020

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

artículo científico publicado en 2020

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

artículo científico publicado en 2020

Recent advances in the study of human antibody responses to influenza virus using optimized human hybridoma approaches

artículo científico publicado en 2009

Recognition of influenza H3N2 variant virus by human neutralizing antibodies

scientific article published on July 2016

Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice

artículo científico publicado en 1994

Recurrent Achromobacter xylosoxidans Bacteremia Associated with Persistent Lymph Node Infection in a Patient with Hyper-Immunoglobulin M Syndrome

scientific article published on 06 November 2000

Recurrent Pneumococcal Arthritis as the Presenting Manifestation of X-Linked Agammaglobulinemia

artículo científico publicado en 2000

Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth

artículo científico publicado en 2015

Reply to Schlapbach et al

scientific article published in 2011

Respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins

artículo científico publicado en 2012

Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication

artículo científico publicado en 2010

Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains

artículo científico publicado en 2003

Respiratory syncytial virus regulates human microRNAs by using mechanisms involving beta interferon and NF-κB.

artículo científico publicado en 2012

Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2

artículo científico publicado en 2008

Respiratory syncytial virus vaccine development

artículo científico publicado en 2001

Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency

artículo científico publicado en 2013

Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.

artículo científico publicado en 2017

Role of antibody heavy and light chain interface residues in affinity maturation of binding to HIV envelope glycoprotein

article

Rotavirus-specific CD5+ B cells in young children exhibit a distinct antibody repertoire compared with CD5- B cells

artículo científico publicado en 2006

STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge

artículo científico publicado en 2014

Satisfactorily attenuated and protective mutants derived from a partially attenuated cold-passaged respiratory syncytial virus mutant by introduction of additional attenuating mutations during chemical mutagenesis

artículo científico publicado en 1994

Secondary mechanisms of diversification in the human antibody repertoire.

artículo científico publicado en 2013

Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes

artículo científico publicado en 2010

Simultaneous Exposure to Intracellular and Extracellular Photosensitizers for the Treatment of Staphylococcus aureus Infections

artículo científico publicado en 2021

Single molecule-sensitive probes for imaging RNA in live cells

artículo científico publicado en 2009

Smallpox Vaccination Does Not Elevate Systemic Levels of Prothrombotic Proteins Associated with Ischemic Cardiac Events

scientific article published in 2005

Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model

artículo científico publicado en 2015

Specificity for human hemoglobin enhances Staphylococcus aureus infection

artículo científico publicado en 2010

Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection

artículo científico publicado en 2015

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

artículo científico publicado en 2010

Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies

artículo científico publicado en 2019

Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains

artículo científico publicado en 2019

Structural basis for Marburg virus neutralization by a cross-reactive human antibody

artículo científico publicado en 2015

Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus

artículo científico publicado en 2017

Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein

artículo científico publicado en 2016

Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody

artículo científico publicado en 2016

Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site

artículo científico publicado en 2012

Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.

artículo científico publicado en 2017

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

artículo científico publicado en 2016

Surfing a genetic association interaction network to identify modulators of antibody response to smallpox vaccine

artículo científico publicado en 2010

Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms.

artículo científico publicado en 2017

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Teaching a Clone to Walk, One Step at a Time

artículo científico publicado en 2016

The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding

artículo científico publicado en 2018

The Transmembrane Domain of the Respiratory Syncytial Virus F Protein Is an Orientation-Independent Apical Plasma Membrane Sorting Sequence

artículo científico publicado en 2006

The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity

artículo científico publicado en 2005

The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations

artículo científico publicado en 2009

The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner

artículo científico publicado en 2002

The live attenuated subgroup B respiratory syncytial virus vaccine candidate RSV 2B33F is attenuated and immunogenic in chimpanzees, but exhibits partial loss of the ts phenotype following replication in vivo

artículo científico publicado en 1999

The pediatric burden of human coronaviruses evaluated for twenty years

scientific article published on August 2009

The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein

artículo científico publicado en 2013

The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience

artículo científico publicado en 2005

The transmembrane domain of the respiratory syncytial virus F protein is an orientation-independent apical plasma membrane sorting sequence

artículo científico publicado en 2005

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques

artículo científico publicado en 2017

Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody.

artículo científico publicado en 2017

Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis

artículo científico publicado en 2017

Tissue-specific expressed antibody variable gene repertoires

artículo científico publicado en 2014

Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection

artículo científico publicado en 2006

Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival

artículo científico publicado en 2012

Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools

artículo científico publicado en 2007

Transcriptional Control of Activation-Induced Cytidine Deaminase and Error-Prone DNA Polymerases Is Functionally Mature in the B Cells of Infants at Birth

artículo científico publicado en 2006

Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection

artículo científico publicado en 2010

Treating Flu with Skin of Frog.

artículo científico publicado en 2017

Universal flu vaccines: primum non nocere

artículo científico publicado en 2013

Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine

artículo científico publicado en 2012

Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies

artículo científico

Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site

artículo científico publicado en 2007

VH1-46 is the dominant immunoglobulin heavy chain gene segment in rotavirus-specific memory B cells expressing the intestinal homing receptor alpha4beta7.

artículo científico publicado en 2005

Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine: a randomized controlled trial

artículo científico publicado en 2004

Vaccine innovations for emerging infectious diseases-a symposium report

scientific article published on 28 October 2019

Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites

artículo científico publicado en 2015

Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats

artículo científico publicado en 2007

Viral Pneumonia

Viral Pneumonia

scholarly article published 2006

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