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Lista de obras de Manfred Uhr

A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression

artículo científico publicado en 2009

A mega-analysis of genome-wide association studies for major depressive disorder

artículo científico publicado en 2012

A polymorphism in the Crhr1 gene determines stress vulnerability in male mice

artículo científico publicado en 2014

ABC drug transporter at the blood-brain barrier: effects on drug metabolism and drug response

artículo científico publicado en 2006

ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder

artículo científico publicado en 2003

ABCB1 genotyping in the treatment of depression

artículo científico publicado en 2016

Acute antidepressive efficacy of lithium monotherapy, not citalopram, depends on recurrent course of depression

artículo científico publicado en 2013

Acute cortisol administration increases sleep depth and growth hormone release in patients with major depression

artículo científico publicado en 2008

Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression

artículo científico publicado en 2005

Affective set-shifting deficits in patients with major depression in remission

artículo científico publicado en 2012

Alcohol administration acutely inhibits ghrelin secretion in an experiment involving psychosocial stress

artículo científico publicado en 2007

Alcohol administration attenuates hypothalamic-pituitary-adrenal (HPA) activity in healthy men at low genetic risk for alcoholism, but not in high-risk subjects

artículo científico publicado en 2012

Analyzing pathways from childhood maltreatment to internalizing symptoms and disorders in children and adolescents (AMIS): a study protocol

artículo científico publicado en 2015

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease

artículo científico publicado en 2013

Association between response to lithium augmentation and the combined DEX/CRH test in major depressive disorder

artículo científico publicado en 2003

Association of ABCB1 gene variants, plasma antidepressant concentration, and treatment response: Results from a randomized clinical study

artículo científico publicado en 2015

Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans

artículo científico publicado en 2014

Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients

artículo científico publicado en 2010

Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders

artículo científico publicado en 2007

Blood-brain barrier penetration and pharmacokinetics of amitriptyline and its metabolites in p-glycoprotein (abcb1ab) knock-out mice and controls

artículo científico publicado en 2006

Cerebrospinal fluid analyses for the diagnosis of subarachnoid haemorrhage and experience from a Swedish study. What method is preferable when diagnosing a subarachnoid haemorrhage?

artículo científico publicado en 2013

Cerebrospinal fluid biomarkers for major depression confirm relevance of associated pathophysiology

artículo científico publicado en 2011

Changes in the hypothalamic-pituitary-adrenal axis and leptin levels during antidepressant treatment

artículo científico publicado en 2007

Changes of sleep architecture, spectral composition of sleep EEG, the nocturnal secretion of cortisol, ACTH, GH, prolactin, melatonin, ghrelin, and leptin, and the DEX-CRH test in depressed patients during treatment with mirtazapine

artículo científico publicado en 2006

Childhood abuse and depression in adulthood: The mediating role of allostatic load

Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project

artículo científico

Combined Dexamethasone/Corticotropin Releasing Hormone Test Predicts Treatment Response in Major Depression–A Potential Biomarker?

artículo científico publicado en 2006

Commentary: The importance of exploring dose-dependent, subtype-specific, and age-related effects of maltreatment on the HPA axis and the mediating link to psychopathology. A response to Fisher (2017).

artículo científico publicado en 2017

Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity

artículo científico publicado en 2017

Dexamethasone stimulated gene expression in peripheral blood indicates glucocorticoid-receptor hypersensitivity in job-related exhaustion

artículo científico publicado en 2014

Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients

artículo científico publicado en 2012

Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption ⬇️

artículo científico publicado el 15 de octubre de 2003

Effect of ethanol on hypothalamic-pituitary-adrenal system response to psychosocial stress in sons of alcohol-dependent fathers

artículo científico publicado en 2004

Effect of mirtazapine on metabolism and energy substrate partitioning in healthy men

scholarly article by Johannes M Hennings et al published 10 January 2019 in JCI insight

Effect of psychosocial stress on FKBP5 and NR3C1 gene expression in healthy young men

article

Effects of Hypericum extract (LI160) on the change of auditory evoked potentials by cortisol administration

artículo científico publicado en 2004

Effects of ghrelin on psychopathology, sleep and secretion of cortisol and growth hormone in patients with major depression

artículo científico publicado en 2011

Endocrine rhythms in patients with restless legs syndrome

artículo científico publicado en 2002

Erratum: Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients

article

Ethanol administration dampens the prolactin response to psychosocial stress exposure in sons of alcohol-dependent fathers

artículo científico publicado en 2009

Ethyl-eicosapentaenoate and dexamethasone resistance in therapy-refractory depression

artículo científico publicado en 2004

Evaluation of the comparability of commercial ghrelin assays

artículo científico publicado en 2004

Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis

scientific journal article

Evidence for a normal HPA axis response to psychosocial stress in patients remitted from depression

artículo científico publicado en 2013

FKBP5 Gene Expression Predicts Antidepressant Treatment Outcome in Depression

article

FKBP5 genotype-dependent DNA methylation and mRNA regulation after psychosocial stress in remitted depression and healthy controls

artículo científico publicado en 2014

FKBP5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children

artículo científico publicado en 2015

Fatigue and regulation of the hypothalamo-pituitary-adrenal axis in multiple sclerosis

artículo científico publicado en 2005

Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response

artículo científico publicado en 2010

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

artículo científico publicado en 2015

Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks

artículo científico publicado en 2011

Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation

artículo científico publicado en 2008

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

artículo científico publicado en 2013

Ghrelin affects the hypothalamus-pituitary-thyroid axis in humans by increasing free thyroxine and decreasing TSH in plasma

artículo científico publicado en 2010

Ghrelin alone or co-administered with GHRH or CRH increases non-REM sleep and decreases REM sleep in young males

artículo científico publicado en 2008

Ghrelin enhances the nocturnal secretion of cortisol and growth hormone in young females without influencing sleep

artículo científico publicado en 2007

Ghrelin increases slow wave sleep and stage 2 sleep and decreases stage 1 sleep and REM sleep in elderly men but does not affect sleep in elderly women

artículo científico publicado en 2009

Ghrelin levels increase after pictures showing food.

artículo científico publicado en 2012

Ghrelin stimulates appetite, imagination of food, GH, ACTH, and cortisol, but does not affect leptin in normal controls

artículo científico publicado en 2005

Ghrelin suppresses nocturnal secretion of luteinizing hormone (LH) and thyroid stimulating hormone (TSH) in patients with major depression

artículo científico publicado en 2013

Ghrelin suppresses secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in women

artículo científico publicado en 2012

Glyoxalase-I mRNA expression and CCK-4 induced panic attacks

artículo científico publicado en 2010

Hair cortisol in maltreated children and adolescents: Importance of developmental period and maltreatment characteristics

scholarly article by Tobias Stalder et al published September 2016 in Psychoneuroendocrinology

Hexarelin decreases slow-wave sleep and stimulates the secretion of GH, ACTH, cortisol and prolactin during sleep in healthy volunteers

artículo científico publicado en 2004

High-affinity CRF1 receptor antagonist NBI-34041: preclinical and clinical data suggest safety and efficacy in attenuating elevated stress response

artículo científico publicado en 2007

Hypothalamic-pituitary-adrenocortical system and mood disorders: highlights from mutant mice

artículo científico publicado en 2004

IGF-I in major depression and antidepressant treatment response

artículo científico publicado en 2015

Identification and characterization of HPA-axis reactivity endophenotypes in a cohort of female PTSD patients

artículo científico publicado en 2015

Impact of citalopram on the HPA system. A study of the combined DEX/CRH test in 30 unipolar depressed patients.

artículo científico publicado en 2011

Impact on cortisol and antidepressant efficacy of quetiapine and escitalopram in depression

artículo científico publicado en 2013

Increased HPA axis response to psychosocial stress in remitted depression: the influence of coping style

artículo científico publicado en 2014

Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study

artículo científico publicado en 2011

Lipid raft integrity affects GABAA receptor, but not NMDA receptor modulation by psychopharmacological compounds

artículo científico publicado en 2012

Lithium augmentation increases post-dexamethasone cortisol in the dexamethasone suppression test in unipolar major depression

artículo científico publicado en 2003

Lithium augmentation increases the ACTH and cortisol response in the combined DEX/CRH test in unipolar major depression

artículo científico publicado en 2002

Lithium monotherapy increases ACTH and cortisol response in the DEX/CRH test in unipolar depressed subjects. A study with 30 treatment-naive patients

artículo científico publicado en 2011

Long-term outcome after lithium augmentation in unipolar depression: focus on HPA system activity

artículo científico publicado en 2009

Mechanisms underlying the protective potential of alpha-tocopherol (vitamin E) against haloperidol-associated neurotoxicity

artículo científico publicado en 2002

Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: A translational approach

Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: a translational approach

artículo científico publicado en 2014

Monthly intravenous methylprednisolone in relapsing-remitting multiple sclerosis - reduction of enhancing lesions, T2 lesion volume and plasma prolactin concentrations

artículo científico publicado en 2006

Nocturnal ghrelin levels--relationship to sleep EEG, the levels of growth hormone, ACTH and cortisol--and gender differences

artículo científico publicado en 2005

Outcome in delusional depression comparing trimipramine monotherapy with a combination of amitriptyline and haloperidol--a double-blind multicenter trial

artículo científico publicado en 2008

P-glycoprotein has negligible effects on estradiol and testosterone in mice

artículo científico publicado en 2007

P-glycoprotein is a factor in the uptake of dextromethorphan, but not of melperone, into the mouse brain: evidence for an overlap in substrate specificity between P-gp and CYP2D6.

artículo científico publicado en 2004

P-glycoprotein reduces the ability of amitriptyline metabolites to cross the blood brain barrier in mice after a 10-day administration of amitriptyline

artículo científico publicado en 2004

P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder

artículo científico publicado en 2006

PTSD psychotherapy improves blood pressure but leaves HPA axis feedback sensitivity stable and unaffected: First evidence from a pre-post treatment study

artículo científico publicado en 2018

Pharmacokinetics of acute and sub-chronic aripiprazole in P-glycoprotein deficient mice

artículo científico publicado en 2010

Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment

artículo científico publicado en 2004

Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls

artículo científico publicado en 2008

Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients

artículo científico

Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression

artículo científico publicado en 2008

Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder

artículo científico publicado en 2007

Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder

artículo científico publicado en 2007

Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach

artículo científico publicado en 2013

Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters

artículo científico publicado en 2005

Psychiatric patient stratification using biosignatures based on cerebrospinal fluid protein expression clusters

artículo científico publicado en 2013

Purine and pyrimidine metabolism: Convergent evidence on chronic antidepressant treatment response in mice and humans

artículo científico publicado en 2016

Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence

artículo científico publicado en 2017

Reduction of hypothalamic vasopressinergic hyperdrive contributes to clinically relevant behavioral and neuroendocrine effects of chronic paroxetine treatment in a psychopathological rat model.

artículo científico publicado en 2002

Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder

artículo científico publicado en 2006

Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization

artículo científico publicado en 2016

Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels

artículo científico publicado en 2012

Selective inhibitors of the FK506-binding protein 51 by induced fit

artículo científico publicado en 2015

Sex-related differential response to dexamethasone in endocrine and immune measures in depressed in-patients and healthy controls

artículo científico publicado en 2018

Sleep and active renin levels--interaction with age, gender, growth hormone and cortisol

artículo científico publicado en 2010

Sleep enhances nocturnal plasma ghrelin levels in healthy subjects.

artículo científico publicado en 2004

Steroid synthesis inhibition with ketoconazole and its effect upon the regulation of the hypothalamus-pituitary-adrenal system in healthy humans

artículo científico publicado en 2002

Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis

artículo científico publicado en 2006

Successful treatment of chronic fatigue syndrome with duloxetine and trijodthyronine--a case study

artículo científico publicado en 2008

Suppressive effect of mirtazapine on the HPA system in acutely depressed women seems to be transient and not related to antidepressant action

artículo científico publicado en 2008

TDM in psychiatry and neurology: A comprehensive summary of the consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology, update 2017; a tool for clinicians<sup/>.

artículo científico publicado en 2018

The Role of mA/m-RNA Methylation in Stress Response Regulation

article published in 2018

The amino acid transporter SLC6A15 is a regulator of hippocampal neurochemistry and behavior

artículo científico publicado en 2015

The anti-Parkinson drug budipine is exported actively out of the brain by P-glycoprotein in mice

artículo científico publicado en 2005

The bio-distribution of the antidepressant clomipramine is modulated by chronic stress in mice: effects on behavior

artículo científico publicado en 2014

The clinical application of ABCB1 genotyping in antidepressant treatment: a pilot study

artículo científico

The clinical impact of ABCB1 polymorphisms on the treatment of psychiatric diseases

artículo científico

The effect of treatment with ketoconazole on central CRH systems of depressed patients ⬇️

artículo científico publicado el 1 de enero de 2011

The influence of Hatha yoga as an add-on treatment in major depression on hypothalamic-pituitary-adrenal-axis activity: a randomized trial

artículo científico publicado en 2014

The neuronal transporter gene SLC6A15 confers risk to major depression

artículo científico publicado en 2011

Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests

artículo científico publicado en 2016

Treatment of depression with the CRH-1-receptor antagonist R121919: endocrine changes and side effects ⬇️

artículo científico publicado el 1 de noviembre de 2003

Treatment with a CRH-1-receptor antagonist (R121919) does not affect weight or plasma leptin concentration in patients with major depression

artículo científico publicado en 2005

Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes

artículo científico publicado en 2009

Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome

artículo científico publicado en 2008

Vasopressin in CSF and plasma in depressed suicide attempters: preliminary results

artículo científico publicado en 2002

[Erratum to: Therapeutic drug monitoring in neuropsychopharmacology : Summary of the consensus guidelines 2017 of the TDM task force of the AGNP]

scientific article published on 01 September 2019

[Therapeutic drug monitoring in neuropsychopharmacology : Summary of the consensus guidelines 2017 of the TDM task force of the AGNP]

scientific article published on 01 May 2019

abcb1ab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice

artículo científico publicado en 2003

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