Lista de obras - Mieke Dewerchin - Dominio Público Uruguay

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

artículo científico publicado en 2004

A key role for transketolase-like 1 in tumor metabolic reprogramming

scientific article published on 06 July 2016

A transgenic Xenopus laevis reporter model to study lymphangiogenesis

artículo científico publicado en 2013

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

artículo científico publicado en 2020

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

scientific article published on 01 January 2020

Angiogenesis Revisited: An Overlooked Role of Endothelial Cell Metabolism in Vessel Sprouting

artículo científico

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

artículo científico publicado en 2007

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

artículo científico publicado en 2002

BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization

artículo científico publicado en 2020

Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha

scientific journal article

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease

artículo científico publicado en 2017

Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development

scientific journal article

De novo design of a biologically active amyloid. ⬇️

artículo científico publicado en 2016

Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism

artículo científico publicado en 2016

EndoDB: a database of endothelial cell transcriptomics data

artículo científico publicado en 2019

Erratum: Corrigendum: Fatty acid carbon is essential for dNTP synthesis in endothelial cells

scientific article published in Nature

FAF1, a gene that is disrupted in cleft palate and has conserved function in zebrafish

artículo científico publicado en 2011

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

artículo científico publicado en 2015

Gender-specific modulation of the response to arterial injury by soluble guanylate cyclase α1.

artículo científico publicado en 2009

Glycolytic regulation of cell rearrangement in angiogenesis.

artículo científico publicado en 2016

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

artículo científico publicado en 2011

Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism

artículo científico publicado en 2014

Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata

scientific journal article

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

scientific article published on 23 August 2018

Incomplete and transitory decrease of glycolysis: a new paradigm for anti-angiogenic therapy?

artículo científico publicado en 2013

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.

artículo científico publicado en 2016

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

artículo científico publicado en 2013

Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery

artículo científico publicado en 2009

Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity

artículo científico publicado en 2009

Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

scientific journal article

Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons

scientific journal article

Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

scientific journal article

Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia

artículo científico publicado en 2011

Lymphatics help baby take first breath

artículo científico publicado en 2014

Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.

artículo científico publicado en 2009

Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities

artículo científico publicado en 2016

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis

artículo científico publicado en 2013

PlGF: a multitasking cytokine with disease-restricted activity

artículo científico

Placental growth factor in cancer

artículo científico publicado en 2014

Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease

artículo científico publicado en 2014

Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle

artículo científico publicado en 2021

Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis

artículo científico publicado en 2021

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis ⬇️

artículo científico publicado en 2018

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

artículo científico publicado en 2016

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

artículo científico publicado en 2002

Role and therapeutic potential of dietary ketone bodies in lymph vessel growth

artículo científico publicado en 2019

Role of PFKFB3-driven glycolysis in vessel sprouting

artículo científico publicado en 2013

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

artículo científico publicado en 2003

Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.

artículo científico publicado en 2008

Role of glutamine and interlinked asparagine metabolism in vessel formation ⬇️

artículo científico publicado en 2017

Role of glutamine synthetase in angiogenesis beyond glutamine synthesis ⬇️

artículo científico publicado en 2018

Role of synectin in lymphatic development in zebrafish and frogs

artículo científico publicado en 2010

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

article

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

artículo científico publicado en 2020

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation

scientific article published on 09 December 2019

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

scientific article published on 13 February 2020

Targeted disruption of the murine Plag1 proto-oncogene causes growth retardation and reduced fertility

scientific journal article

The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts

artículo científico publicado en 2015

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

artículo científico publicado en 2016

The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation

scientific journal article

The role of fatty acid β-oxidation in lymphangiogenesis

artículo científico publicado en 2016

Tumor vessel normalization by chloroquine independent of autophagy.

artículo científico publicado en 2014

VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation

artículo científico publicado en 2011

Vascular endothelial growth factor: a neurovascular target in neurological diseases

artículo científico publicado en 2016

uPA deficiency exacerbates muscular dystrophy in MDX mice

artículo científico publicado en 2007

Lista de obras de Mieke Dewerchin

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

A key role for transketolase-like 1 in tumor metabolic reprogramming

A transgenic Xenopus laevis reporter model to study lymphangiogenesis

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

Angiogenesis Revisited: An Overlooked Role of Endothelial Cell Metabolism in Vessel Sprouting

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization

Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease

Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development

De novo design of a biologically active amyloid. ⬇️

Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism

EndoDB: a database of endothelial cell transcriptomics data

Erratum: Corrigendum: Fatty acid carbon is essential for dNTP synthesis in endothelial cells

FAF1, a gene that is disrupted in cleft palate and has conserved function in zebrafish

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Gender-specific modulation of the response to arterial injury by soluble guanylate cyclase α1.

Glycolytic regulation of cell rearrangement in angiogenesis.

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism

Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

Incomplete and transitory decrease of glycolysis: a new paradigm for anti-angiogenic therapy?

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery

Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity

Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons

Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia

Lymphatics help baby take first breath

Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.

Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis

PlGF: a multitasking cytokine with disease-restricted activity

Placental growth factor in cancer

Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease

Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle

Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis ⬇️

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

Role and therapeutic potential of dietary ketone bodies in lymph vessel growth

Role of PFKFB3-driven glycolysis in vessel sprouting

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.

Role of glutamine and interlinked asparagine metabolism in vessel formation ⬇️

Role of glutamine synthetase in angiogenesis beyond glutamine synthesis ⬇️

Role of synectin in lymphatic development in zebrafish and frogs

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

Targeted disruption of the murine Plag1 proto-oncogene causes growth retardation and reduced fertility

The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation

The role of fatty acid β-oxidation in lymphangiogenesis

Tumor vessel normalization by chloroquine independent of autophagy.

VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation

Vascular endothelial growth factor: a neurovascular target in neurological diseases

uPA deficiency exacerbates muscular dystrophy in MDX mice