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Lista de obras de Milan Mrksich

3-Hydroxypyridin-2-thione as novel zinc binding group for selective histone deacetylase inhibition

artículo científico publicado en 2013

A Bottom-Up Proteomic Approach to Identify Substrate Specificity of Outer-Membrane Protease OmpT.

artículo científico publicado en 2017

A Photoactivatable Reaction for Covalent Nanoscale Patterning of Multiple Proteins

artículo científico publicado en 2018

A Self‐Adjuvanting Supramolecular Vaccine Carrying a Folded Protein Antigen ⬇️

artículo científico publicado el 25 de febrero de 2013

A calcium-modulated plasmonic switch

artículo científico publicado en 2008

A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

scientific article published on 27 November 2019

A comparative analysis of localized and propagating surface plasmon resonance sensors: the binding of concanavalin a to a monosaccharide functionalized self-assembled monolayer

artículo científico publicado en 2004

A conformation- and ion-sensitive plasmonic biosensor.

artículo científico publicado en 2011

A gene expression-based comparison of cell adhesion to extracellular matrix and RGD-terminated monolayers

artículo científico publicado en 2015

A high-throughput SAMDI-mass spectrometry assay for isocitrate dehydrogenase 1 ⬇️

scientific article published on 16 April 2020

A method for connecting solution-phase enzyme activity assays with immobilized format analysis by mass spectrometry

artículo científico publicado en 2004

A photochemical method for patterning the immobilization of ligands and cells to self-assembled monolayers

artículo científico publicado en 2004

A spatially propagating biochemical reaction.

artículo científico publicado en 2010

A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities

artículo científico publicado en 2015

A substituent effects study reveals the kinetic pathway for an interfacial reaction.

artículo científico publicado en 2004

Acetyltransferase p300/CBP associated Factor (PCAF) regulates crosstalk-dependent acetylation of histone H3 by distal site recognition

artículo científico publicado en 2014

Active Site Metal Identity Alters Histone Deacetylase 8 Substrate Selectivity: A Potential Novel Regulatory Mechanism

artículo científico publicado en 2017

An Assay Based on SAMDI Mass Spectrometry for Profiling Protein Interaction Domains.

artículo científico publicado en 2017

An Immobilized Enzyme Reactor for Spatiotemporal Control over Reaction Products

artículo científico publicado en 2018

An Unusual Salt Effect in an Interfacial Nucleophilic Substitution Reaction

artículo científico publicado en 2018

An adaptor domain-mediated autocatalytic interfacial kinase reaction.

artículo científico publicado en 2009

An early taste of functional glycomics

artículo científico publicado en 2004

An inhibitor of a cell adhesion receptor stimulates cell migration

artículo científico publicado en 2010

Antibody arrays prepared by cutinase-mediated immobilization on self-assembled monolayers.

artículo científico publicado en 2004

Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin ⬇️

artículo científico publicado el 15 de agosto de 1992

Assays of endogenous caspase activities: a comparison of mass spectrometry and fluorescence formats

artículo científico publicado en 2006

Author Correction: Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery

artículo científico publicado en 2018

Binding affinities of synthetic peptides, pyridine-2-carboxamidonetropsin and 1-methylimidazole-2-carboxamidonetropsin, that form 2:1 complexes in the minor groove of double-helical DNA.

artículo científico

Biochemical assays of immobilized oligonucleotides with mass spectrometry

artículo científico publicado en 2008

Bisboronic Acids for Selective, Physiologically Relevant Direct Glucose Sensing with Surface-Enhanced Raman Spectroscopy

artículo científico publicado en 2016

Cancer prognostics by direct detection of p53-antibodies on gold surfaces by impedance measurements.

artículo científico publicado en 2012

Carbohydrate arrays for the evaluation of protein binding and enzymatic modification

artículo científico publicado en 2002

Cell adhesion to unnatural ligands mediated by a bifunctional protein

artículo científico publicado en 2010

Cell-Based Screening: Cellular Assays with a Molecular Endpoint Measured by SAMDI Mass Spectrometry (Small 28/2016).

artículo científico publicado en 2016

Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria

artículo científico publicado en 2022

Cellular Assays with a Molecular Endpoint Measured by SAMDI Mass Spectrometry

artículo científico publicado en 2016

Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor

artículo científico publicado en 2004

Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

artículo científico publicado en 2013

Combinatorial screening of mesenchymal stem cell adhesion and differentiation using polymer pen lithography

artículo científico publicado en 2014

Combining carbochips and mass spectrometry to study the donor specificity for the Neisseria meningitidis β1,3-N-acetylglucosaminyltransferase LgtA.

artículo científico publicado en 2011

Combining mass spectrometry and peptide arrays to profile the specificities of histone deacetylases.

artículo científico publicado en 2009

Combining microfluidic networks and peptide arrays for multi-enzyme assays.

artículo científico publicado en 2005

Combining self-assembled monolayers and mass spectrometry for applications in biochips

artículo científico publicado en 2008

Computational planning of the synthesis of complex natural products

artículo científico publicado en 2020

De novo motif for kinase mediated signaling across the cell membrane.

artículo científico publicado en 2011

Dependence of the rate of an interfacial Diels-Alder reaction on the steric environment of the immobilized dienophile: an example of enthalpy-entropy compensation

artículo científico publicado en 2002

Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids

artículo científico publicado en 2015

Design of a G.C-specific DNA minor groove-binding peptide.

artículo científico

Design of glycosylation sites by rapid synthesis and analysis of glycosyltransferases

artículo científico publicado en 2018

Detection and Identification of Bioanalytes with High Resolution LSPR Spectroscopy and MALDI Mass Spectrometry

artículo científico publicado en 2009

Detection of differentially expressed basal cell proteins by mass spectrometry

artículo científico publicado en 2009

Determination of kinetic parameters for interfacial enzymatic reactions on self-assembled monolayers

artículo científico publicado en 2007

Directing stem cell fate by controlling the affinity and density of ligand-receptor interactions at the biomaterials interface

scientific article published on 13 April 2012

Discovery of SIRT3 Inhibitors Using SAMDI Mass Spectrometry

scientific article published on 29 May 2015

Discovery of a small molecule that inhibits the interaction of anthrax edema factor with its cellular activator, calmodulin

artículo científico publicado en 2004

Discovery of glycosyltransferases using carbohydrate arrays and mass spectrometry

artículo científico publicado en 2012

Dynamic hydrogels: translating a protein conformational change into macroscopic motion

artículo científico publicado en 2007

Dynamic interfaces between cells and surfaces: electroactive substrates that sequentially release and attach cells

artículo científico publicado en 2003

Efficient Solid-Phase Synthesis of Peptide-Substituted Alkanethiols for the Preparation of Substrates That Support the Adhesion of Cells

scientific article published on 01 October 1998

Electroactive monolayer substrates that selectively release adherent cells.

artículo científico publicado en 2001

Electroactive self-assembled monolayers that permit orthogonal control over the adhesion of cells to patterned substrates

artículo científico publicado en 2006

Electrochemical desorption of self-assembled monolayers noninvasively releases patterned cells from geometrical confinements

artículo científico publicado en 2003

Engineering a biospecific communication pathway between cells and electrodes

artículo científico publicado en 2006

Enzymatic synthesis and properties of uridine-5'-O-(2-thiodiphospho)-N-acetylglucosamine

artículo científico publicado en 2011

Evidence that a minor groove-binding peptide and a major groove-binding protein can simultaneously occupy a common site on DNA

artículo científico publicado el 17 de noviembre de 1992

Exploration of the nanomedicine-design space with high-throughput screening and machine learning

scientific article published on 18 February 2019

Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3

scientific article published on 14 December 2020

Extending the recognition site of designed minor groove binding molecules

artículo científico publicado en 1996

Functional assays of membrane-bound proteins with SAMDI-TOF mass spectrometry

artículo científico publicado en 2007

Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates

artículo científico publicado en 1999

Geometric cues for directing the differentiation of mesenchymal stem cells

artículo científico publicado en 2010

High Throughput Screening with SAMDI Mass Spectrometry for Directed Evolution

artículo científico publicado en 2020

High-Throughput Enzyme Kinetics with 3D Microfluidics and Imaging SAMDI Mass Spectrometry

scientific article published on 10 October 2018

High-Throughput Synthesis and Analysis of Intact Glycoproteins Using SAMDI-MS

scientific article published on 07 January 2020

High-throughput photocapture approach for reaction discovery

artículo científico publicado en 2020

High-throughput screening of small molecule libraries using SAMDI mass spectrometry

artículo científico publicado en 2011

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.

artículo científico publicado en 2006

Immunoisolating pancreatic islets by encapsulation with selective withdrawal

article

Label-Free Assay of Protein Tyrosine Phosphatase Activity in Single Cells

scientific article published on 26 September 2019

Label-assisted mass spectrometry for the acceleration of reaction discovery and optimization

artículo científico publicado en 2013

Label-free detection of protein-protein interactions on biochips

artículo científico publicado en 2005

Long-Range Energy Transfer in Protein Megamolecules

scientific article published in 2018

Machine Learning on Signal-to-Noise Ratios Improves Peptide Array Design in SAMDI Mass Spectrometry

artículo científico publicado en 2017

Mass spectrometry of self-assembled monolayers: a new tool for molecular surface science

artículo científico publicado en 2008

Measuring Drug Metabolism Kinetics and Drug-Drug Interactions Using Self-Assembled Monolayers for Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

artículo científico publicado en 2016

Micropatterned dynamically adhesive substrates for cell migration

artículo científico publicado en 2010

Micropatterned surfaces for control of cell shape, position, and function

artículo científico publicado en 1998

Micropatterning Facilitates the Long-Term Growth and Analysis of iPSC-Derived Individual Human Neurons and Neuronal Networks.

artículo científico publicado en 2016

Modular assembly of protein building blocks to create precisely defined megamolecules.

artículo científico publicado en 2012

Nanopatterned Extracellular Matrices Enable Cell-Based Assays with a Mass Spectrometric Readout

artículo científico publicado en 2017

Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton

artículo científico publicado en 2010

On-chip synthesis and label-free assays of oligosaccharide arrays

artículo científico publicado en 2008

On-line detection of nonspecific protein adsorption at artificial surfaces

artículo científico publicado en 1997

Patterning multiple aligned self-assembled monolayers using light.

artículo científico publicado en 2004

Peptide Arrays: Development and Application

artículo científico publicado en 2017

Peptide arrays identify isoform-selective substrates for profiling endogenous lysine deacetylase activity

artículo científico publicado en 2010

Peptide arrays: towards routine implementation

artículo científico publicado en 2004

Peptide chips for the quantitative evaluation of protein kinase activity

artículo científico publicado en 2002

Peptide delivery with poly(ethylene glycol) diacrylate microneedles through swelling effect.

artículo científico publicado en 2017

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

artículo científico publicado en 2014

Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins

artículo científico publicado en 2002

Plasmonic Microneedle Arrays for in Situ Sensing with Surface-Enhanced Raman Spectroscopy (SERS)

scientific article published on 01 October 2019

Plectin-containing, centrally localized focal adhesions exert traction forces in primary lung epithelial cells

artículo científico publicado en 2013

Profiling Protein Tyrosine Phosphatase Specificity with Self-Assembled Monolayers for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Peptide Arrays

scientific article published on 24 October 2019

Profiling deacetylase activities in cell lysates with peptide arrays and SAMDI mass spectrometry

artículo científico publicado en 2013

Profiling kinase activities by using a peptide chip and mass spectrometry

artículo científico publicado en 2004

Profiling the selectivity of DNA ligases in an array format with mass spectrometry

artículo científico publicado en 2009

Protein nanoarrays generated by dip-pen nanolithography

artículo científico publicado en 2002

Rapid evaluation and screening of interfacial reactions on self-assembled monolayers.

artículo científico publicado en 2007

Rate enhancement of an interfacial biochemical reaction through localization of substrate and enzyme by an adaptor domain

artículo científico publicado en 2010

Rewiring cell adhesion.

artículo científico publicado en 2004

SAMDI Mass Spectrometry-Enabled High-Throughput Optimization of a Traceless Petasis Reaction

artículo científico publicado en 2015

SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation

artículo científico publicado en 2016

SP19 Label-Free Detection of Kinase Activities and Protein-Protein Interactions on BioChips

artículo científico publicado en 2007

Selective immobilization of proteins to self-assembled monolayers presenting active site-directed capture ligands

artículo científico publicado en 2002

Self-assembled monolayer facilitates epithelial-mesenchymal interactions mimicking odontogenesis

artículo científico publicado en 2014

Self-assembled monolayers for MALDI-TOF mass spectrometry for immunoassays of human protein antigens

artículo científico publicado en 2007

Self-assembled monolayers that transduce enzymatic activities to electrical signals

artículo científico publicado en 2003

Sequential Glycosylation of Proteins with Substrate-Specific N-Glycosyltransferases

artículo científico publicado en 2020

Sequential Photoactivation of Self-Assembled Monolayers to Direct Cell Adhesion and Migration

scientific article published on 15 April 2019

Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.

artículo científico publicado en 2018

Solid-Phase Synthesis of Megamolecules

artículo científico publicado en 2020

Steady-state of an enzymatic reaction is dependent on the density of reactant

artículo científico publicado en 2012

Stem cell differentiation: Multipotency retained

artículo científico publicado en 2011

Storage of Information Using Small Organic Molecules

artículo científico publicado en 2019

Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin

artículo científico publicado en 2005

Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation

artículo científico publicado en 2014

Structure-based inhibitor discovery against adenylyl cyclase toxins from pathogenic bacteria that cause anthrax and whooping cough

artículo científico publicado en 2003

Subcellular Control over Focal Adhesion Anisotropy, Independent of Cell Morphology, Dictates Stem Cell Fate

artículo científico publicado en 2019

Subcellular curvature at the perimeter of micropatterned cells influences lamellipodial distribution and cell polarity.

artículo científico publicado en 2008

Substrates for cell adhesion prepared via active site-directed immobilization of a protein domain

artículo científico publicado en 2004

Surface molecular recognition ⬇️

artículo científico publicado el 30 de octubre de 2001

Synthesis and structure-activity relationship of 3-hydroxypyridine-2-thione-based histone deacetylase inhibitors

artículo científico publicado en 2013

Synthesis of Cyclic Megamolecules

artículo científico publicado en 2018

Synthetic Tuning of Domain Stoichiometry in Nanobody-Enzyme Megamolecules

artículo científico publicado en 2020

Tailored substrates for studies of attached cell culture ⬇️

artículo científico publicado el 1 de julio de 1998

The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites

artículo científico publicado en 2014

The Kinetic Order of an Interfacial Diels-Alder Reaction Depends on the Environment of the Immobilized Dienophile We are grateful for the support provided by the MRSEC (National Science Foundation, DMR-9808595) and DARPA

artículo científico publicado en 2000

The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors

artículo científico publicado en 2014

The mechanostability of isolated focal adhesions is strongly dependent on pH

artículo científico publicado en 2012

The platelet integrin alphaIIbbeta3 binds to the RGD and AGD motifs in fibrinogen

artículo científico publicado en 2009

The synergy peptide PHSRN and the adhesion peptide RGD mediate cell adhesion through a common mechanism.

artículo científico publicado en 2004

Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers

artículo científico publicado en 2011

Traceless Immobilization of Analytes for High-Throughput Experiments with SAMDI Mass Spectrometry.

artículo científico publicado en 2018

Turning On Cell Migration with Electroactive Substrates We are grateful for support of this work by DARPA and the National Institute of Health (GM 54621). This work used facilities of the MRSEC supported by the National Science Foundation (DMR-98085

artículo científico publicado en 2001

Using Microcontact Printing to Pattern the Attachment of Mammalian Cells to Self-Assembled Monolayers of Alkanethiolates on Transparent Films of Gold and Silver ⬇️

artículo científico publicado el 15 de septiembre de 1997

Using Microfluidics and Imaging SAMDI-MS To Characterize Reaction Kinetics

artículo científico publicado en 2019

Using Peptide Arrays To Discover the Sequence-Specific Acetylation of the Histidine-Tyrosine Dyad

scientific article published on 12 March 2019

Using Peptide Arrays to Profile Phosphatase Activity in Cell Lysates

artículo científico publicado en 2019

Using capillary electrophoresis to follow the acetylation of the amino groups of insulin and to estimate their basicities

artículo científico publicado en 1995

Using capillary electrophoresis to follow the acetylation of the amino groups of insulin and to estimate their basicities

artículo científico publicado en 1996

Using mass spectrometry to characterize self-assembled monolayers presenting peptides, proteins, and carbohydrates.

artículo científico publicado en 2002

Using model substrates to study the dependence of focal adhesion formation on the affinity of integrin-ligand complexes.

artículo científico publicado en 2004

Using selective withdrawal to coat microparticles

artículo científico publicado en 2001

Using self-assembled monolayers to model cell adhesion to the 9th and 10th type III domains of fibronectin

artículo científico publicado en 2009

Using self-assembled monolayers to model the extracellular matrix.

scientific article published on 27 January 2009

Using self-assembled monolayers to understand the interactions of man-made surfaces with proteins and cells.

artículo científico publicado en 1996

Using self-assembled monolayers to understand α8β1-mediated cell adhesion to RGD and FEI motifs in nephronectin

artículo científico publicado en 2011

Using the angle-dependent resonances of molded plasmonic crystals to improve the sensitivities of biosensors.

artículo científico publicado en 2010

What can surface chemistry do for cell biology?

artículo científico publicado en 2002

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