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Lista de obras de David Durantel

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

artículo científico publicado en 2020

A first experience of transduction for differentiated HepaRG cells using lentiviral technology

artículo científico publicado en 2019

A new immune competent mouse model for the study of hepatitis D virus infection

artículo científico publicado en 2017

A new strategy for studying in vitro the drug susceptibility of clinical isolates of human hepatitis B virus.

artículo científico publicado en 2004

A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses.

artículo científico publicado en 2015

Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors

artículo científico publicado en 2015

Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases.

artículo científico publicado en 2013

An immortalized human liver endothelial sinusoidal cell line for the study of the pathobiology of the liver endothelium

artículo científico publicado en 2014

Antiviral activity of various interferons and pro-inflammatory cytokines in non-transformed cultured hepatocytes infected with hepatitis B virus

artículo científico publicado en 2016

Antiviral effect of N-butyldeoxynojirimycin against bovine viral diarrhea virus correlates with misfolding of E2 envelope proteins and impairment of their association into E1-E2 heterodimers

artículo científico publicado en 2001

Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles.

artículo científico publicado en 2006

Antiviral therapies and prospects for a cure of chronic hepatitis B.

artículo científico publicado en 2015

Characterization of Pattern Recognition Receptor Expression and Functionality in Liver Primary Cells and Derived Cell Lines

artículo científico publicado en 2018

Characterization of the Inflammasome in Human Kupffer Cells in Response to Synthetic Agonists and Pathogens.

artículo científico publicado en 2016

Characterization of the double-stranded RNA responses in human liver progenitor cells

artículo científico publicado en 2008

Circulating and Hepatic BDCA1+, BDCA2+, and BDCA3+ Dendritic Cells Are Differentially Subverted in Patients With Chronic HBV Infection

scientific article published on 04 February 2019

Control of hepatitis B virus replication by innate response of HepaRG cells.

artículo científico publicado en 2010

Corrigendum to "Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis" [J Hepatol 71 (2019) 763-772]

artículo científico publicado en 2019

DNA methylation of hepatitis B virus (HBV) genome associated with the development of hepatocellular carcinoma and occult HBV infection

artículo científico publicado en 2010

Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector

artículo científico publicado en 2017

Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes.

artículo científico publicado en 2018

Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells

artículo científico publicado en 2016

Early inhibition of hepatocyte innate responses by hepatitis B virus.

artículo científico publicado en 2015

Effects of interferon, ribavirin, and iminosugar derivatives on cells persistently infected with noncytopathic bovine viral diarrhea virus

artículo científico publicado en 2004

Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus.

artículo científico publicado en 2016

Expression and functionality of Toll- and RIG-like receptors in HepaRG cells.

artículo científico publicado en 2015

Fast Differentiation of HepaRG Cells Allowing Hepatitis B and Delta Virus Infections

artículo científico publicado en 2020

Fitness and infectivity of drug-resistant and cross-resistant hepatitis B virus mutants: why and how is it studied?

artículo científico publicado en 2010

Genetic variability of hepatitis C virus in chronically infected patients with viral breakthrough during interferon-ribavirin therapy

artículo científico publicado en 2004

Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes.

artículo científico publicado en 2015

Going towards more relevant cell culture models to study the in vitro replication of serum-derived hepatitis C virus and virus/host cell interactions?

artículo científico publicado en 2006

HBV infection and HCC: the 'dangerous liaisons'.

artículo científico publicado en 2017

HCV research 20 years after discovery: a summary of the 16th international symposium on hepatitis C virus and related viruses

artículo científico publicado en 2009

HDV RNA replication is associated with HBV repression and interferon-stimulated genes induction in super-infected hepatocytes

artículo científico publicado en 2016

Hepatitis B Virus Blocks the CRE/CREB Complex and Prevents TLR9 Transcription and Function in Human B Cells

scholarly article by Issam Tout et al published 15 October 2018 in Journal of Immunology

Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic young adults

artículo científico publicado en 2018

Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production

artículo científico publicado en 2020

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection.

artículo científico publicado en 2011

Hepatitis B virus evasion from cGAS sensing in human hepatocytes.

artículo científico publicado en 2018

Hepatitis B virus infection enhances susceptibility toward adeno-associated viral vector transduction in vitro and in vivo.

artículo científico publicado en 2014

Hepatitis B virus replication in primary macaque hepatocytes: crossing the species barrier toward a new small primate model.

artículo científico publicado en 2010

Hepatitis B virus requires intact caveolin-1 function for productive infection in HepaRG cells

artículo científico publicado en 2010

Hepatitis B virus-induced modulation of liver macrophage function promotes hepatocyte infection

artículo científico publicado en 2019

Hepatitis C virus fails to activate NF-κB signaling in plasmacytoid dendritic cells

artículo científico publicado en 2011

Hepatitis delta virus: From biological and medical aspects to current and investigational therapeutic options

artículo científico publicado en 2015

Immune-modulators to combat hepatitis B virus infection: From IFN-α to novel investigational immunotherapeutic strategies

artículo científico

In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine.

artículo científico publicado en 2006

Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics

artículo científico publicado en 2011

Initiation of hepatitis B virus genome replication and production of infectious virus following delivery in HepG2 cells by novel recombinant baculovirus vector

artículo científico publicado en 2008

Innate antiviral immune responses to hepatitis B virus.

artículo científico

Innate response to hepatitis B virus infection: Observations challenging the concept of a stealth virus

article

Interaction between TLR9-CpG-ODNs and HBV virions leads to entry inhibition in hepatocytes and reduction of IFNα production by pDC.

artículo científico publicado en 2018

Interplay between hepatitis B virus and TLR2-mediated innate immune responses: Can restoration of TLR2 functions be a new therapeutic option?

artículo científico publicado el 21 de junio de 2012

Interplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts.

artículo científico publicado en 2017

Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B.

artículo científico publicado en 2016

Liver macrophages: Friend or foe during hepatitis B infection?

artículo científico publicado en 2018

Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis

artículo científico publicado en 2013

Management and prevention of drug resistance in chronic hepatitis B.

artículo científico publicado en 2009

Mechanism of action of ribavirin in anti-HCV regimens: new insights for an age-old question?

artículo científico publicado el 9 de mayo de 2013

Mechanisms behind TB, HBV, and HIV chronic infections.

artículo científico publicado en 2017

Meeting report: 31st International Conference on Antiviral Research

artículo científico publicado en 2018

NOD1 Participates in the Innate Immune Response Triggered by Hepatitis C Virus Polymerase

artículo científico publicado en 2016

New antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virus

artículo científico publicado en 2016

New treatments to reach functional cure: Virological approaches.

artículo científico publicado en 2017

Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle

artículo científico publicado en 2018

Novel targets for hepatitis B virus therapy

artículo científico publicado en 2017

Persistence of the hepatitis B virus covalently closed circular DNA in HepaRG human hepatocyte-like cells.

artículo científico publicado en 2009

Polo-like-kinase 1 is a proviral host-factor for hepatitis B virus replication

artículo científico publicado en 2017

RNA helicase DEAD box protein 5 regulates Polycomb repressive complex 2/Hox transcript antisense intergenic RNA function in hepatitis B virus infection and hepatocarcinogenesis

artículo científico publicado en 2016

Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra- and extra-cellular domains

artículo científico publicado en 2009

Reciprocal antagonism between the netrin-1 receptor uncoordinated-phenotype-5A (UNC5A) and the hepatitis C virus

artículo científico

Reduction of the infectivity of hepatitis C virus pseudoparticles by incorporation of misfolded glycoproteins induced by glucosidase inhibitors

artículo científico publicado en 2007

Resistance of human hepatitis B virus to reverse transcriptase inhibitors: from genotypic to phenotypic testing.

artículo científico publicado en 2005

Ribavirin restores IFNα responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes

artículo científico publicado en 2015

Role of disulfide bond formation in the folding and assembly of the envelope glycoproteins of a pestivirus

artículo científico publicado en 2002

Short peptide nucleic acids (PNA) inhibit hepatitis C virus internal ribosome entry site (IRES) dependent translation in vitro.

artículo científico publicado en 2008

Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

artículo científico publicado en 2014

Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development

artículo científico publicado en 2009

Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus

artículo científico publicado en 2001

Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir.

artículo científico publicado en 2005

Synthesis of 1,2,3-triazolo-carbanucleoside analogues of ribavirin targeting an HCV in replicon.

artículo científico publicado en 2003

Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: antiviral activity and cellular toxicity.

artículo científico publicado en 2005

Targeting innate immunity: a new step in the development of combination therapy for chronic hepatitis B.

artículo científico publicado en 2013

Temporal expression of the AcMNPV lef-4 gene and subcellular localization of the protein.

artículo científico publicado en 1998

The HepaRG cell line: biological properties and relevance as a tool for cell biology, drug metabolism, and virology studies.

artículo científico publicado en 2010

The diverse functions of the hepatitis B core/capsid protein (HBc) in the viral life cycle: Implications for the development of HBc-targeting antivirals.

artículo científico publicado en 2017

Toll-Like Receptor 7 Agonist GS-9620 Induces Prolonged Inhibition of HBV via a Type I Interferon-Dependent Mechanism

artículo científico publicado en 2017

Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis

scientific article published on 18 June 2019

Towards an HBV cure: state-of-the-art and unresolved questions--report of the ANRS workshop on HBV cure.

artículo científico publicado en 2015

Treatment of hepatitis B virus-infected cells with alpha-glucosidase inhibitors results in production of virions with altered molecular composition and infectivity.

artículo científico publicado en 2007

Very-low-density lipoprotein (VLDL)-producing and hepatitis C virus-replicating HepG2 cells secrete no more lipoviroparticles than VLDL-deficient Huh7.5 cells.

artículo científico publicado en 2013

Who Defends the Stem Cell's Citadel?

artículo científico publicado en 2018