Lista de obras - Caetano Reis e Sousa - Dominio Público Uruguay

2011 ESCI Award for Excellence in Basic / Translational Research: innate regulation of adaptive immunity by dendritic cells ⬇️

artículo científico publicado el 26 de mayo de 2011

A pH- and ionic strength-dependent conformational change in the neck region regulates DNGR-1 function in dendritic cells

artículo científico publicado en 2016

Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster

artículo científico publicado en 2016

Activation of MDA5 requires higher-order RNA structures generated during virus infection

artículo científico publicado en 2009

Activation of dendritic cells: translating innate into adaptive immunity

artículo científico publicado en 2004

Adaptive immunity after cell death ⬇️

artículo científico publicado el 20 de abril de 2013

Advantages and limitations of mouse models to deplete dendritic cells

artículo científico publicado en 2013

Alive but Confused: Heterogeneity of CD11c + MHC Class II + Cells in GM-CSF Mouse Bone Marrow Cultures

article

Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells.

artículo científico publicado en 2014

An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma

artículo científico publicado en 2011

Analysis of adjuvant function by direct visualization of antigen presentation in vivo: endotoxin promotes accumulation of antigen-bearing dendritic cells in the T cell areas of lymphoid tissue

article

Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates

artículo científico publicado en 2015

Antigen processing

artículo científico publicado en 2013

Antigen-unspecific B cells and lymphoid dendritic cells both show extensive surface expression of processed antigen-major histocompatibility complex class II complexes after soluble protein exposure in vivo or in vitro.

artículo científico publicado en 1997

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

artículo científico publicado en 2014

CCR5 provides a signal for microbial induced production of IL-12 by CD8α+ dendritic cells

article

CD36 or alphavbeta3 and alphavbeta5 integrins are not essential for MHC class I cross-presentation of cell-associated antigen by CD8 alpha+ murine dendritic cells

artículo científico publicado en 2002

CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal

artículo científico publicado en 2000

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

artículo científico publicado en 2012

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.

artículo científico publicado en 2011

CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils.

artículo científico publicado en 2009

CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses

artículo científico publicado en 2011

Caetano Reis e Sousa: harnessing DC power. Interview by Hema Bashyam

artículo científico publicado en 2008

Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells

artículo científico publicado en 2010

Clec9a-Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells In Vivo.

artículo científico publicado en 2018

Conditioning of dendritic cells by pathogen-derived stimuli.

artículo científico publicado en 2001

Correction: Syk Signaling in Dendritic Cells Orchestrates Innate Resistance to Systemic Fungal Infection

artículo científico publicado en 2018

Cross-presentation of cell-associated antigens by CD8alpha+ dendritic cells is attributable to their ability to internalize dead cells

artículo científico publicado en 2002

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.

artículo científico publicado en 2015

Cytoskeletal Exposure in the Regulation of Immunity and Initiation of Tissue Repair

scientific article published on 03 June 2019

Cytosolic sensing of viruses

artículo científico publicado en 2013

DC activated via dectin-1 convert Treg into IL-17 producers

artículo científico publicado en 2008

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues

artículo científico publicado en 2012

Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages

artículo científico publicado en 2004

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

artículo científico publicado en 2009

Defining dendritic cells

artículo científico

Dendritic Cell Lineage Potential in Human Early Hematopoietic Progenitors

artículo científico publicado en 2017

Dendritic cell expression of the Notch ligandjagged2 is not essential for Th2 response inductionin vivo

article

Dendritic cell quiescence during systemic inflammation driven by LPS stimulation of radioresistant cells in vivo

artículo científico publicado en 2007

Dendritic cells as sensors of infection.

artículo científico publicado en 2001

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

artículo científico publicado en 2014

Dendritic cells in a mature age.

artículo científico publicado en 2006

Dendritic cells in remodeling of lymph nodes during immune responses

artículo científico publicado en 2016

Dendritic cells: immunobiology and cancer immunotherapy

artículo científico publicado en 2004

Differential TCR Signaling Regulates Apoptosis and Immunopathology during Antigen Responses In Vivo

article

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

artículo científico publicado en 2006

Direct activation of antigen-presenting cells is required for CD8+ T-cell priming and tumor vaccination

artículo científico publicado en 2011

Direct reprogramming of fibroblasts into antigen-presenting dendritic cells

artículo científico publicado en 2018

Drosha cuts the tethers of myelopoiesis

artículo científico publicado en 2015

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A.

artículo científico publicado en 2010

Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells

scientific journal article

F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells

GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells.

artículo científico publicado en 2015

Gene manipulation in the induction of anti-tumour immunity

artículo científico publicado en 1999

Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage.

artículo científico publicado en 2013

Harnessing dendritic cells ⬇️

artículo científico publicado el 1 de febrero de 2011

Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.

artículo científico publicado en 2015

Hoxb8 conditionally immortalised macrophage lines model inflammatory monocytic cells with important similarity to dendritic cells

artículo científico publicado en 2011

ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro

article

IL-12 Induction by a Th1-Inducing Adjuvant In Vivo: Dendritic Cell Subsets and Regulation by IL-10

scientific article published on 01 August 2001

IL-17 regulates systemic fungal immunity by controlling the functional competence of NK cells

artículo científico publicado en 2014

IMMUNOLOGY: Eating In to Avoid Infection

scientific article published in Science

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

artículo científico publicado en 2009

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

artículo científico publicado en 2014

Ignition of the type 1 response to intracellular infection by dendritic cell-derived interleukin-12.

artículo científico publicado en 1998

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas ⬇️

artículo científico publicado el 1 de diciembre de 1997

Inactivation of the type I interferon pathway reveals long double-stranded RNA-mediated RNA interference in mammalian cells.

artículo científico publicado en 2016

Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

article by Roman Spörri & Caetano Reis e Sousa published 16 January 2005 in Nature Immunology

Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

artículo científico publicado en 2009

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

scientific journal article

Innate recognition of viruses

artículo científico publicado en 2007

Internalization of Dectin-1 terminates induction of inflammatory responses

artículo científico publicado en 2009

Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

artículo científico publicado en 2015

Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity

artículo científico publicado en 2001

MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells

artículo científico publicado en 2004

Microbial and T Cell-Derived Stimuli Regulate Antigen Presentation by Dendritic Cells In Vivo

scientific article published on 01 November 2000

Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering

artículo científico publicado en 2002

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.

artículo científico publicado en 2018

Molecular mimicry of a CCR5 binding-domain in the microbial activation of dendritic cells

artículo científico publicado en 2003

Mouse superkiller-2-like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses.

artículo científico publicado en 2015

Myeloid C-type Lectin Receptors in Pathogen Recognition and Host Defense ⬇️

artículo científico publicado el 27 de mayo de 2011

Myeloid C-type lectins in innate immunity

artículo científico publicado en 2006

Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens

artículo científico publicado en 2018

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

artículo científico publicado en 2018

Newly activated T cells promote maturation of bystander dendritic cells but not IL-12 production

article

Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides

scientific article published on 01 December 2006

Oncogenic Transformation of Dendritic Cells and Their Precursors Leads to Rapid Cancer Development in Mice

artículo científico publicado en 2015

PYHIN proteins: center stage in DNA sensing

Paralysis of Dendritic Cell IL-12 Production by Microbial Products Prevents Infection-Induced Immunopathology

article

Phagocytosis of antigens by Langerhans cells

artículo científico publicado en 1993

Processing and presentation of endocytically acquired protein antigens by MHC class II and class I molecules

artículo científico publicado en 1996

Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes

artículo científico publicado en 2013

Production, specificity, and functionality of monoclonal antibodies to specific peptide–major histocompatibility complex class II complexes formed by processing of exogenous protein ⬇️

artículo científico publicado el 9 de diciembre de 1997

Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity

artículo científico publicado en 2010

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

artículo científico publicado en 2010

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

artículo científico publicado en 2006

RIGorous detection: exposing virus through RNA sensing

artículo científico publicado en 2010

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

artículo científico publicado en 2015

RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency

artículo científico publicado en 2022

Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity

artículo científico publicado en 2021

Reducing prostaglandin E2 production to raise cancer immunogenicity

artículo científico publicado en 2016

Relationships among murine CD11c(high) dendritic cell subsets as revealed by baseline gene expression patterns

artículo científico

SAMHD1-dependent retroviral control and escape in mice.

artículo científico publicado en 2013

SAMHD1-dependent retroviral control and escape in mice.

artículo científico publicado en 2013

Selective induction of apoptosis in mature T lymphocytes by variant T cell receptor ligands.

artículo científico publicado en 1998

Self peptide/MHC class I complexes have a negligible effect on the response of some CD8+ T cells to foreign antigen

artículo científico publicado en 2002

Sensing infection and tissue damage

artículo científico publicado en 2017

Sensing of cell death by myeloid C-type lectin receptors

artículo científico publicado en 2013

Signaling by myeloid C-type lectin receptors in immunity and homeostasis

artículo científico publicado en 2012

Slicing and dicing viruses: antiviral RNA interference in mammals

artículo científico publicado en 2019

Stimulation of dendritic cells via the dectin-1/Syk pathway allows priming of cytotoxic T-cell responses

artículo científico publicado en 2008

Syk signaling in dendritic cells orchestrates innate resistance to systemic fungal infection.

artículo científico publicado en 2014

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

article by Salomé LeibundGut-Landmann et al published 22 April 2007 in Nature Immunology

Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan

artículo científico publicado en 2007

Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins

scientific journal article

Targeting the viral Achilles’ heel: recognition of 5′-triphosphate RNA in innate anti-viral defence ⬇️

artículo científico publicado el 23 de mayo de 2013

The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice

artículo científico publicado en 2012

The Processed Amino-Terminal Fragment of Human TLR7 Acts as a Chaperone To Direct Human TLR7 into Endosomes

artículo científico publicado en 2015

The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells

artículo científico publicado en 2018

The Role of Type 1 Conventional Dendritic Cells in Cancer Immunity

artículo científico publicado en 2018

The ability of murine dendritic cell subsets to direct T helper cell differentiation is dependent on microbial signals

artículo científico publicado en 2003

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

artículo científico publicado en 2012

The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens

scientific article published on 21 December 2020

The role of dendritic cells in the induction and regulation of immunity to microbial infection.

artículo científico publicado en 1999

The role of dendritic cells in the initiation of host resistance to Toxoplasma gondii.

artículo científico publicado en 1998

Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors

scientific article published on 01 March 2019

Toll-like receptor 3 promotes cross-priming to virus-infected cells.

artículo científico publicado en 2005

Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

artículo científico publicado en 2003

Toll-like receptors and dendritic cells: for whom the bug tolls

artículo científico publicado en 2004

Tubulovesicular structures within vesicular stomatitis virus G protein-pseudotyped lentiviral vector preparations carry DNA and stimulate antiviral responses via Toll-like receptor 9.

artículo científico publicado en 2006

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

artículo científico publicado en 2008

Viral infection switches non-plasmacytoid dendritic cells into high interferon producers.

artículo científico publicado en 2003

Vitamin D regulates microbiome-dependent cancer immunity

artículo científico publicado en 2024

α-actinin accounts for the bioactivity of actin preparations in inducing STAT target genes in

article

Lista de obras de Caetano Reis e Sousa

2011 ESCI Award for Excellence in Basic / Translational Research: innate regulation of adaptive immunity by dendritic cells ⬇️

A pH- and ionic strength-dependent conformational change in the neck region regulates DNGR-1 function in dendritic cells

Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster

Activation of MDA5 requires higher-order RNA structures generated during virus infection

Activation of dendritic cells: translating innate into adaptive immunity

Adaptive immunity after cell death ⬇️

Advantages and limitations of mouse models to deplete dendritic cells

Alive but Confused: Heterogeneity of CD11c + MHC Class II + Cells in GM-CSF Mouse Bone Marrow Cultures

Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells.

An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma

Analysis of adjuvant function by direct visualization of antigen presentation in vivo: endotoxin promotes accumulation of antigen-bearing dendritic cells in the T cell areas of lymphoid tissue

Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates

Antigen processing

Antigen-unspecific B cells and lymphoid dendritic cells both show extensive surface expression of processed antigen-major histocompatibility complex class II complexes after soluble protein exposure in vivo or in vitro.

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

CCR5 provides a signal for microbial induced production of IL-12 by CD8α+ dendritic cells

CD36 or alphavbeta3 and alphavbeta5 integrins are not essential for MHC class I cross-presentation of cell-associated antigen by CD8 alpha+ murine dendritic cells

CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.

CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils.

CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses

Caetano Reis e Sousa: harnessing DC power. Interview by Hema Bashyam

Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells

Clec9a-Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells In Vivo.

Conditioning of dendritic cells by pathogen-derived stimuli.

Correction: Syk Signaling in Dendritic Cells Orchestrates Innate Resistance to Systemic Fungal Infection

Cross-presentation of cell-associated antigens by CD8alpha+ dendritic cells is attributable to their ability to internalize dead cells

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.

Cytoskeletal Exposure in the Regulation of Immunity and Initiation of Tissue Repair

Cytosolic sensing of viruses

DC activated via dectin-1 convert Treg into IL-17 producers

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues

Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

Defining dendritic cells

Dendritic Cell Lineage Potential in Human Early Hematopoietic Progenitors

Dendritic cell expression of the Notch ligandjagged2 is not essential for Th2 response inductionin vivo

Dendritic cell quiescence during systemic inflammation driven by LPS stimulation of radioresistant cells in vivo

Dendritic cells as sensors of infection.

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

Dendritic cells in a mature age.

Dendritic cells in remodeling of lymph nodes during immune responses

Dendritic cells: immunobiology and cancer immunotherapy

Differential TCR Signaling Regulates Apoptosis and Immunopathology during Antigen Responses In Vivo

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Direct activation of antigen-presenting cells is required for CD8+ T-cell priming and tumor vaccination

Direct reprogramming of fibroblasts into antigen-presenting dendritic cells

Drosha cuts the tethers of myelopoiesis

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A.

Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells

F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells

GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells.

Gene manipulation in the induction of anti-tumour immunity

Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage.

Harnessing dendritic cells ⬇️

Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.

Hoxb8 conditionally immortalised macrophage lines model inflammatory monocytic cells with important similarity to dendritic cells

ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro

IL-12 Induction by a Th1-Inducing Adjuvant In Vivo: Dendritic Cell Subsets and Regulation by IL-10

IL-17 regulates systemic fungal immunity by controlling the functional competence of NK cells

IMMUNOLOGY: Eating In to Avoid Infection

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

Ignition of the type 1 response to intracellular infection by dendritic cell-derived interleukin-12.

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas ⬇️

Inactivation of the type I interferon pathway reveals long double-stranded RNA-mediated RNA interference in mammalian cells.

Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

Innate recognition of viruses

Internalization of Dectin-1 terminates induction of inflammatory responses

Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity

MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells

Microbial and T Cell-Derived Stimuli Regulate Antigen Presentation by Dendritic Cells In Vivo

Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.

Molecular mimicry of a CCR5 binding-domain in the microbial activation of dendritic cells