Lista de obras - Klemens Rottner - Dominio Público Uruguay

A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion

artículo científico publicado en 2016

A novel contractility pathway operating in Salmonella invasion.

artículo científico publicado en 2012

Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes

article

Actin Networks: Adapting to Load through Geometry

artículo científico publicado en 2017

Actin and the coordination of protrusion, attachment and retraction in cell crawling.

artículo científico publicado en 1996

Actin assembly mechanisms at a glance.

artículo científico publicado en 2017

Actin branching in the initiation and maintenance of lamellipodia

artículo científico publicado en 2012

Actin dynamics and turnover in cell motility.

artículo científico publicado en 2011

Actin dynamics in cell migration

artículo científico publicado en 2019

Actin-based motility of Burkholderia pseudomallei involves the Arp 2/3 complex, but not N-WASP and Ena/VASP proteins

artículo científico publicado en 2003

Activation of a RhoA/myosin II-dependent but Arp2/3 complex-independent pathway facilitates Salmonella invasion.

artículo científico publicado en 2011

Arp2/3 complex interactions and actin network turnover in lamellipodia.

artículo científico publicado en 2008

Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin

artículo científico publicado en 2013

Assembling actin filaments for protrusion

scientific article published on 01 October 2018

Assembling an actin cytoskeleton for cell attachment and movement

artículo científico publicado en 1998

Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

scientific article published on 26 November 2019

Bacteria-host-cell interactions at the plasma membrane: stories on actin cytoskeleton subversion.

artículo científico publicado en 2005

Biomedical Research Publication System

artículo científico publicado en 2004

CELL BIOLOGY. Formin' filaments at a faster CLIP.

artículo científico publicado en 2016

Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways

artículo científico publicado en 2007

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

artículo científico publicado en 2005

Cell-substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime

artículo científico publicado en 2020

Cofilin cooperates with fascin to disassemble filopodial actin filaments

artículo científico publicado en 2011

Control of high affinity interactions in the talin C terminus: how talin domains coordinate protein dynamics in cell adhesions.

artículo científico publicado en 2009

Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis

artículo científico publicado en 2017

Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivo

artículo científico publicado en 2011

Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.

artículo científico publicado en 2009

Cortactin regulates the activity of small GTPases and ICAM-1 clustering in endothelium: Implications for the formation of docking structures

artículo científico publicado en 2013

Cortactin: Cell Functions of A Multifaceted Actin-Binding Protein

artículo científico publicado en 2017

Cytoskeleton cross-talk during cell motility.

artículo científico publicado en 1999

Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein

artículo científico publicado en 2013

Differential functions of WAVE regulatory complex subunits in the regulation of actin-driven processes

artículo científico publicado en 2017

Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front

Distinct Interaction Sites of Rac GTPase with WAVE Regulatory Complex Have Non-redundant Functions in Vivo

artículo científico publicado en 2018

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain

artículo científico publicado en 2016

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes

artículo científico publicado en 2016

Early cell death induced by Clostridium difficile TcdB: Uptake and Rac1-glucosylation kinetics are decisive for cell fate

artículo científico publicado en 2018

Efficiency of lamellipodia protrusion is determined by the extent of cytosolic actin assembly

artículo científico publicado en 2017

Elementary Cellular Processes Driven by Actin Assembly: Lamellipodia and Filopodia

Enterohaemorrhagic and enteropathogenic Escherichia coli use different mechanisms for actin pedestal formation that converge on N-WASP.

artículo científico publicado en 2004

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

artículo científico publicado en 2011

Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1.

artículo científico publicado en 2013

F- and G-actin concentrations in lamellipodia of moving cells

artículo científico publicado en 2009

FMNL formins boost lamellipodial force generation

artículo científico publicado en 2017

FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42.

artículo científico

FMNL2 drives actin-based protrusion and migration downstream of Cdc42.

artículo científico publicado en 2012

Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes

artículo científico publicado en 2006

Filopodia formation induced by active mDia2/Drf3.

artículo científico publicado en 2008

Filopodia: Complex models for simple rods.

artículo científico publicado en 2009

ForC lacks canonical formin activity but bundles actin filaments and is required for multicellular development of Dictyostelium cells

artículo científico publicado en 2013

Functional design in the actin cytoskeleton

artículo científico publicado en 1999

Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins

scientific article published on 11 February 2019

High cortactin expression in B-cell acute lymphoblastic leukemia is associated with increased transendothelial migration and bone marrow relapse

scientific article published on 20 December 2018

Host-Pathogen Interactions and Cell Motility: Learning from Bacteria

How distinct Arp2/3 complex variants regulate actin filament assembly

artículo científico publicado en 2015

IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation.

artículo científico publicado en 2009

Imaging the Molecular Machines That Power Cell Migration.

artículo científico publicado en 2018

Inhibitory signalling to the Arp2/3 complex steers cell migration

artículo científico publicado en 2013

Interplay between Rac and Rho in the control of substrate contact dynamics

artículo científico publicado en 1999

Intima-like smooth muscle cells: developmental link between endothelium and media?

artículo científico publicado en 1999

Introduction to Small GTPases

artículo científico publicado en 2010

Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading.

artículo científico publicado en 2017

Lamellipodia-like actin networks in cells lacking WAVE Regulatory Complex

artículo científico publicado en 2021

Live imaging of glioblastoma cells in brain tissue shows requirement of actin bundles for migration

artículo científico publicado en 2006

Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion

artículo científico publicado en 2020

Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility

artículo científico publicado en 2016

MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7.

artículo científico publicado en 2008

Metavinculin: New insights into functional properties of a muscle adhesion protein

artículo científico publicado en 2012

Micromanipulation Techniques Allowing Analysis of Morphogenetic Dynamics and Turnover of Cytoskeletal Regulators

artículo científico publicado en 2018

Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.

artículo científico publicado en 2013

Microtubules as platforms for assaying actin polymerization in vivo

artículo científico publicado en 2011

Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping

artículo científico publicado en 2010

Molecular dissection of Salmonella-induced membrane ruffling versus invasion

artículo científico publicado en 2009

Monomeric red fluorescent protein variants used for imaging studies in different species

artículo científico publicado en 2006

N-WASP deficiency impairs EGF internalization and actin assembly at clathrin-coated pits

scientific article published on 28 June 2005

Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion.

artículo científico publicado en 2014

On the Rho'd: the regulation of membrane protrusions by Rho-GTPases

artículo científico publicado en 2008

On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility.

artículo científico publicado en 2018

Pathogen-induced actin filament rearrangement in infectious diseases.

artículo científico publicado en 2004

Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nck, WIP, and Grb2

scientific article (publication date: 4 October 2002)

Poxviruses Taking a Ride on Actin: New Users of Known Hardware

artículo científico publicado en 2009

Prevention of the cytopathic effect induced by Clostridium difficile Toxin B by active Rac1.

artículo científico publicado en 2008

Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

artículo científico publicado en 2013

Rac1-dependent recruitment of PAK2 to G2 phase centrosomes and their roles in the regulation of mitotic entry

artículo científico publicado en 2014

Regulation of actin dynamics by WASP and WAVE family proteins.

artículo científico publicado en 2004

Requirements for and consequences of Rac-dependent protrusion

artículo científico publicado en 2014

Retraction: The association between the microtubule plus end protein EB1 and cortactin controls podosomes and bone resorption

RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

artículo científico publicado en 2011

RhoA, Rac1 and Cdc42 differentially regulate aSMA and collagen I expression in mesenchymal stem cells.

artículo científico publicado en 2018

RhoG and Cdc42 can contribute to Rac-dependent lamellipodia formation through WAVE regulatory complex-binding

scientific article published on 26 August 2019

Role of the WASP family proteins for Mycobacterium marinum actin tail formation

artículo científico publicado en 2005

Serine-71 phosphorylation of Rac1 modulates downstream signaling

artículo científico publicado en 2012

Sex steroid-opioid interactions associated with the temporal component of avian calling patterns

artículo científico publicado en 1996

Signalling Pathways Controlling Cellular Actin Organization

artículo científico publicado en 2016

Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

artículo científico publicado en 2004

Structure of Shigella IpgB2 in Complex with Human RhoA: IMPLICATIONS FOR THE MECHANISM OF BACTERIAL GUANINE NUCLEOTIDE EXCHANGE FACTOR MIMICRY

artículo científico publicado en 2010

Targeting, capture, and stabilization of microtubules at early focal adhesions

artículo científico publicado en 1998

The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia

artículo científico publicado en 2001

The Arp2/3 complex is critical for colonisation of the mouse skin by melanoblasts

artículo científico publicado en 2020

The Small GTPase Rac1 Increases Cell Surface Stiffness and Enhances 3D Migration Into Extracellular Matrices

artículo científico publicado en 2019

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity

scientific article published on 01 July 2020

The lamellipodium: where motility begins

artículo científico publicado en 2002

The making of filopodia

artículo científico publicado en 2005

The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation.

artículo científico publicado en 2015

The vinculin-DeltaIn20/21 mouse: characteristics of a constitutive, actin-binding deficient splice variant of vinculin

artículo científico publicado en 2010

Transient Activations of Rac1 at the Lamellipodium Tip Trigger Membrane Protrusion

artículo científico publicado en 2019

VASP dynamics during lamellipodia protrusion

article

Visualising the actin cytoskeleton

artículo científico publicado en 1999

WASH, WHAMM and JMY: regulation of Arp2/3 complex and beyond

artículo científico publicado en 2010

Xin repeats define a novel actin-binding motif.

artículo científico publicado en 2004

Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions

artículo científico publicado en 2001

Lista de obras de Klemens Rottner

A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion

A novel contractility pathway operating in Salmonella invasion.

Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes

Actin Networks: Adapting to Load through Geometry

Actin and the coordination of protrusion, attachment and retraction in cell crawling.

Actin assembly mechanisms at a glance.

Actin branching in the initiation and maintenance of lamellipodia

Actin dynamics and turnover in cell motility.

Actin dynamics in cell migration

Actin-based motility of Burkholderia pseudomallei involves the Arp 2/3 complex, but not N-WASP and Ena/VASP proteins

Activation of a RhoA/myosin II-dependent but Arp2/3 complex-independent pathway facilitates Salmonella invasion.

Arp2/3 complex interactions and actin network turnover in lamellipodia.

Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin

Assembling actin filaments for protrusion

Assembling an actin cytoskeleton for cell attachment and movement

Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

Bacteria-host-cell interactions at the plasma membrane: stories on actin cytoskeleton subversion.

Biomedical Research Publication System

CELL BIOLOGY. Formin' filaments at a faster CLIP.

Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

Cell-substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime

Cofilin cooperates with fascin to disassemble filopodial actin filaments

Control of high affinity interactions in the talin C terminus: how talin domains coordinate protein dynamics in cell adhesions.

Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis

Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivo

Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.

Cortactin regulates the activity of small GTPases and ICAM-1 clustering in endothelium: Implications for the formation of docking structures

Cortactin: Cell Functions of A Multifaceted Actin-Binding Protein

Cytoskeleton cross-talk during cell motility.

Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein

Differential functions of WAVE regulatory complex subunits in the regulation of actin-driven processes

Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front

Distinct Interaction Sites of Rac GTPase with WAVE Regulatory Complex Have Non-redundant Functions in Vivo

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes

Early cell death induced by Clostridium difficile TcdB: Uptake and Rac1-glucosylation kinetics are decisive for cell fate

Efficiency of lamellipodia protrusion is determined by the extent of cytosolic actin assembly

Elementary Cellular Processes Driven by Actin Assembly: Lamellipodia and Filopodia

Enterohaemorrhagic and enteropathogenic Escherichia coli use different mechanisms for actin pedestal formation that converge on N-WASP.

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1.

F- and G-actin concentrations in lamellipodia of moving cells

FMNL formins boost lamellipodial force generation

FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42.

FMNL2 drives actin-based protrusion and migration downstream of Cdc42.

Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes

Filopodia formation induced by active mDia2/Drf3.

Filopodia: Complex models for simple rods.

ForC lacks canonical formin activity but bundles actin filaments and is required for multicellular development of Dictyostelium cells

Functional design in the actin cytoskeleton

Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins

High cortactin expression in B-cell acute lymphoblastic leukemia is associated with increased transendothelial migration and bone marrow relapse

Host-Pathogen Interactions and Cell Motility: Learning from Bacteria

How distinct Arp2/3 complex variants regulate actin filament assembly

IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation.

Imaging the Molecular Machines That Power Cell Migration.

Inhibitory signalling to the Arp2/3 complex steers cell migration

Interplay between Rac and Rho in the control of substrate contact dynamics

Intima-like smooth muscle cells: developmental link between endothelium and media?

Introduction to Small GTPases

Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading.

Lamellipodia-like actin networks in cells lacking WAVE Regulatory Complex

Live imaging of glioblastoma cells in brain tissue shows requirement of actin bundles for migration

Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion

Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility

MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7.

Metavinculin: New insights into functional properties of a muscle adhesion protein

Micromanipulation Techniques Allowing Analysis of Morphogenetic Dynamics and Turnover of Cytoskeletal Regulators

Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.

Microtubules as platforms for assaying actin polymerization in vivo

Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping

Molecular dissection of Salmonella-induced membrane ruffling versus invasion

Monomeric red fluorescent protein variants used for imaging studies in different species

N-WASP deficiency impairs EGF internalization and actin assembly at clathrin-coated pits

Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion.

On the Rho'd: the regulation of membrane protrusions by Rho-GTPases

On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility.

Pathogen-induced actin filament rearrangement in infectious diseases.