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Lista de obras de Sina Bavari

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

artículo científico publicado en 2020

3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells

artículo científico publicado en 2010

4-Amino-7-chloroquinolines: probing ligand efficiency provides botulinum neurotoxin serotype A light chain inhibitors with significant antiprotozoal activity

scientific article published on 12 July 2013

A Call for Randomized Controlled Trials to Test the Efficacy of Chloroquine and Hydroxychloroquine as Therapeutics against Novel Coronavirus Disease (COVID-19)

artículo científico publicado en 2020

A Novel Toll-Like Receptor 2 Agonist Protects Mice in a Prophylactic Treatment Model Against Challenge With <i>Bacillus anthracis</i>

artículo científico publicado en 2022

A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has a Very Different Conformation than SNAP-25 Substrate

artículo científico publicado en 2008

A STAT-1 knockout mouse model for Machupo virus pathogenesis

artículo científico publicado en 2011

A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.

artículo científico publicado en 2011

A high content imaging assay for identification of Botulinum neurotoxin inhibitors

artículo científico publicado en 2014

A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages.

artículo científico publicado en 2014

A limited structural modification results in a significantly more efficacious diazachrysene-based filovirus inhibitor

artículo científico publicado en 2012

A race for an Ebola vaccine: promises and obstacles

artículo científico publicado en 2014

A recombinant single-chain human class II MHC molecule (HLA-DR1) as a covalently linked heterotrimer of alpha chain, beta chain, and antigenic peptide, with immunogenicity in vitro and reduced affinity for bacterial superantigens.

artículo científico

A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease

artículo científico publicado en 2007

A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection

artículo científico publicado en 2015

A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection

artículo científico publicado en 2015

A systematic screen of FDA-approved drugs for inhibitors of biological threat agents

artículo científico publicado en 2013

A thermostable, chromatographically purified Ebola nano-VLP vaccine

artículo científico publicado en 2015

AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.

artículo científico publicado en 2016

AVI-7288 for Marburg Virus in Nonhuman Primates and Humans

artículo científico publicado en 2015

Adjuvant selection impacts the correlates of vaccine protection against Ebola infection

artículo científico publicado en 2020

Adjuvant-enhanced CD4 T Cell Responses are Critical to Durable Vaccine Immunity

artículo científico publicado en 2015

Advanced antisense therapies for postexposure protection against lethal filovirus infections.

artículo científico publicado en 2010

Advanced morpholino oligomers: a novel approach to antiviral therapy

artículo científico publicado en 2012

African and Asian Zika Virus Isolates Display Phenotypic Differences Both In Vitro and In Vivo.

artículo científico publicado en 2017

Alkylated porphyrins have broad antiviral activity against hepadnaviruses, flaviviruses, filoviruses, and arenaviruses

artículo científico publicado en 2010

Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns

artículo científico publicado en 2014

An all-atom model of the pore-like structure of hexameric VP40 from Ebola: structural insights into the monomer-hexamer transition.

artículo científico publicado en 2005

Analysis of Ebola virus and VLP release using an immunocapture assay.

artículo científico publicado en 2005

Analysis of botulinum neurotoxin serotype A metalloprotease inhibitors: analogs of a chemotype for therapeutic&amp;nbsp; development in the context of a three-zone pharmacophore ⬇️

artículo científico publicado el 1 de abril de 2010

Animal Models of Viral Hemorrhagic Fevers

Animal models for ebolavirus countermeasures discovery: what defines a useful model?

artículo científico

Anthrax biosensor, protective antigen ion channel asymmetric blockade.

artículo científico publicado en 2005

Anthrax lethal toxin impairs innate immune functions of alveolar macrophages and facilitates Bacillus anthracis survival

artículo científico publicado en 2006

Anthrax toxin-induced rupture of artificial lipid bilayer membranes

artículo científico publicado en 2013

Antisense treatments for biothreat agents.

artículo científico publicado en 2006

Antiviral activity of a small-molecule inhibitor of filovirus infection

artículo científico publicado en 2010

Antiviral therapeutics for the treatment of Ebola virus infection

artículo científico publicado en 2016

Application of carbohydrate microarray technology for the detection of Burkholderia pseudomallei, Bacillus anthracis and Francisella tularensis antibodies.

artículo científico publicado en 2008

Applications of in vivo imaging in the evaluation of the pathophysiology of viral and bacterial infections and in development of countermeasures to BSL3/4 pathogens

artículo científico publicado en 2015

Approach to Cataract Surgery in an Ebola Virus Disease Survivor with Prior Ocular Viral Persistence

scientific article published on 01 July 2020

Arenaviruses: Hemorrhagic Fevers

Arenaviruses: Hemorrhagic Fevers

Assembly of Ebola virus matrix protein VP40 is regulated by latch-like properties of N and C terminal tails

artículo científico publicado en 2012

Assembly of a functional Machupo virus polymerase complex

artículo científico publicado en 2010

Association of ebola virus matrix protein VP40 with microtubules

artículo científico publicado en 2005

Asymptomatic Ebola virus infections-myth or reality?

artículo científico publicado en 2017

Author Correction: Histology, immunohistochemistry, and in situ hybridization reveal overlooked Ebola virus target tissues in the Ebola virus disease guinea pig model

artículo científico publicado en 2019

Avoidance behavior independent of innate-immune signaling seen in Caenorhabditis elegans challenged with Bacillus anthracis

scientific article published on 18 July 2019

BCX4430 - A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease

artículo científico publicado en 2016

BRILIA: Integrated Tool for High-Throughput Annotation and Lineage Tree Assembly of B-Cell Repertoires

artículo científico publicado en 2016

Biochip for the Detection of Bacillus anthracis Lethal Factor and Therapeutic Agents against Anthrax Toxins.

artículo científico publicado en 2016

Bis-imidazolinylindoles are active against methicillin-resistant Staphylococcus aureus and multidrug-resistant Mycobacterium tuberculosis.

artículo científico publicado en 2012

Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus

artículo científico publicado en 2016

Bolivian Hemorrhagic Fever

Broad-spectrum Investigational Agent GS-5734 for the Treatment of Ebola, MERS Coronavirus and Other Pathogenic Viral Infections with High Outbreak Potential.

artículo científico publicado en 2017

Broad-spectrum coronavirus antiviral drug discovery

artículo científico publicado en 2019

Characterization of Ebola Virus Disease (EVD) in Rhesus Monkeys for Development of EVD Therapeutics

scientific article published on 13 January 2020

Characterization of a putative filovirus vaccine: virus-like particles

artículo científico

Characterization of clinical and immunological parameters during Ebola virus infection of rhesus macaques

artículo científico publicado en 2015

Characterization of the Burkholderia thailandensis SOS response by using whole-transcriptome shotgun sequencing

artículo científico publicado en 2013

Characterization of the murine macrophage response to infection with virulent and avirulent Burkholderia species.

artículo científico publicado en 2015

Characterization of the plasma proteome of nonhuman primates during Ebola virus disease or melioidosis: a host response comparison

scientific article published on 07 February 2019

Chemical genetic screening identifies critical pathways in anthrax lethal toxin-induced pathogenesis

artículo científico publicado en 2007

Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection

artículo científico publicado en 2009

Chimpanzee adenovirus type 3 vectored Ebola vaccine: expanding the field

artículo científico publicado en 2020

Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo

scientific article published on 29 August 2019

Clinical Laboratory Values as Early Indicators of Ebola Virus Infection in Nonhuman Primates

artículo científico

Clinical Laboratory Values in Human Ebola Virus Disease Support the Relevance of the Intramuscular Ebola-Kikwit Rhesus Model

artículo científico publicado en 2017

Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates

artículo científico publicado en 2010

Conformational sampling of the botulinum neurotoxin serotype A light chain: implications for inhibitor binding.

artículo científico publicado en 2005

Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor

artículo científico publicado en 2006

Considerations for the development of Zika virus vaccines

artículo científico publicado en 2016

Correlates of immunity to filovirus infection

artículo científico publicado en 2011

Correlation of body temperature with protection against staphylococcal enterotoxin B exposure and use in determining vaccine dose-schedule

artículo científico publicado en 2003

Countering Zika Virus: The USAMRIID Response.

artículo científico publicado en 2018

Crimean-Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway

artículo científico publicado en 2013

Crimean-Congo hemorrhagic fever: current and future prospects of vaccines and therapies

artículo científico publicado en 2011

Cross-protection conferred by filovirus virus-like particles containing trimeric hybrid glycoprotein

artículo científico publicado en 2015

Cross-reactive antibodies prevent the lethal effects of Staphylococcus aureus superantigens

scientific article published on 01 October 1999

Current status of chemically synthesized inhibitors of Ebola virus

artículo científico

DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection

artículo científico publicado en 2018

Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques

artículo científico publicado en 2016

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose

artículo científico publicado en 2016

Dendritic cells endocytose Bacillus anthracis spores: implications for anthrax pathogenesis.

artículo científico publicado en 2005

Detection of Highly Pathogenic Viral Agents

Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication

artículo científico publicado en 2017

Development and characterization of a mouse model for Marburg hemorrhagic fever

artículo científico publicado en 2009

Development and characterization of rabbit and mouse antibodies against ebolavirus envelope glycoproteins

artículo científico publicado en 2011

Development of a broad-spectrum antiviral with activity against Ebola virus

artículo científico publicado en 2009

Development of a liquid chromatography high resolution mass spectrometry method for the quantitation of viral envelope glycoprotein in Ebola virus-like particle vaccine preparations

artículo científico publicado en 2016

Development of a model for marburgvirus based on severe-combined immunodeficiency mice

artículo científico publicado en 2007

Development of cell-based assays to measure botulinum neurotoxin serotype A activity using cleavage-sensitive antibodies

artículo científico publicado en 2009

Development of engineered vaccines effective against structurally related bacterial superantigens

artículo científico publicado en 1998

Development of high-content imaging assays for lethal viral pathogens.

artículo científico publicado en 2010

Discovering Drugs for the Treatment of Ebola Virus.

artículo científico publicado en 2017

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

artículo científico publicado en 2017

Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections

artículo científico publicado en 2012

Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1

artículo científico publicado en 2017

Discovery of common marburgvirus protective epitopes in a BALB/c mouse model

scientific article published on 27 August 2009

Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus

artículo científico publicado en 2011

Dominance of human innate immune responses in primary Francisella tularensis live vaccine strain vaccination

artículo científico publicado en 2006

Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses

artículo científico publicado en 2012

Ebola Virus Causes Intestinal Tract Architectural Disruption and Bacterial Invasion in Non-Human Primates

scientific article published on 20 September 2018

Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study: Reverse Transcription-Polymerase Chain Reaction and Cataract Surgery Outcomes of Ebola Survivors in Sierra Leone.

artículo científico publicado en 2018

Ebola and Marburg virus-like particles activate human myeloid dendritic cells

artículo científico publicado en 2004

Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation

artículo científico publicado en 2003

Ebola virus disease candidate vaccines under evaluation in clinical trials

artículo científico publicado en 2016

Ebola virus genome plasticity as a marker of its passaging history: a comparison of in vitro passaging to non-human primate infection

artículo científico publicado en 2012

Ebola virus glycoprotein Fc fusion protein confers protection against lethal challenge in vaccinated mice

artículo científico publicado en 2011

Ebola virus inactivation with preservation of antigenic and structural integrity by a photoinducible alkylating agent

artículo científico publicado en 2007

Ebola virus uses clathrin-mediated endocytosis as an entry pathway

artículo científico publicado en 2010

Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge

artículo científico publicado en 2007

Ebola virus-like particles protect from lethal Ebola virus infection

artículo científico publicado en 2003

Ebola virus-like particles stimulate type I interferons and proinflammatory cytokine expression through the toll-like receptor and interferon signaling pathways.

scientific article published on 08 October 2013

Ebolavirus Glycoprotein Fc Fusion Protein Protects Guinea Pigs against Lethal Challenge

artículo científico publicado en 2016

Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry

artículo científico publicado en 2011

Efficacy of favipiravir (T-705) in nonhuman primates infected with Ebola virus or Marburg virus.

artículo científico publicado en 2017

Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR.

artículo científico publicado en 2010

Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery

artículo científico publicado en 2011

Emergence of Ebola Virus Escape Variants in Infected Nonhuman Primates Treated with the MB-003 Antibody Cocktail

artículo científico publicado en 2015

Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo

artículo científico publicado en 2017

Evaluation of Ebola Virus Inhibitors for Drug Repurposing.

artículo científico publicado en 2015

Evaluation of perceived threat differences posed by filovirus variants

artículo científico publicado en 2011

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names

artículo científico publicado en 2014

Filovirus infections

artículo científico publicado en 2009

Filovirus vaccines.

artículo científico publicado en 2011

Filovirus-like particles as vaccines and discovery tools

artículo científico publicado en 2005

Filovirus-like particles produced in insect cells: immunogenicity and protection in rodents

artículo científico publicado en 2007

Filoviruses: Hemorrhagic Fevers

Filoviruses: Hemorrhagic Fevers

Flex-nucleoside analogues - Novel therapeutics against filoviruses

artículo científico publicado en 2017

Functional CD8+ T cell responses in lethal Ebola virus infection

artículo científico publicado en 2008

Gaining ground: assays for therapeutics against botulinum neurotoxin

scientific article published on 04 March 2010

Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers.

artículo científico publicado en 2006

Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B.

artículo científico publicado en 2010

Generation of Marburg virus-like particles by co-expression of glycoprotein and matrix protein

artículo científico publicado en 2004

Generation of heterogeneous memory T cells by live attenuated tularemia vaccine in humans

artículo científico publicado en 2009

Generation of protective immunity by inactivated recombinant staphylococcal enterotoxin B vaccine in nonhuman primates and identification of correlates of immunity

artículo científico publicado en 2003

Glucopyranosyl lipid adjuvant enhances immune response to Ebola virus-like particle vaccine in mice

scientific article published on 04 June 2019

HSPA5 is an essential host factor for Ebola virus infection

artículo científico publicado en 2014

Heat fixation inactivates viral and bacterial pathogens and is compatible with downstream MALDI mass spectrometry tissue imaging

artículo científico publicado en 2015

High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus

artículo científico publicado en 2017

High content image based analysis identifies cell cycle inhibitors as regulators of Ebola virus infection

artículo científico publicado en 2012

High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses

artículo científico publicado en 2014

High degree of correlation between Ebola virus BSL-4 neutralization assays and pseudotyped VSV BSL-2 fluorescence reduction neutralization test

artículo científico publicado en 2018

High-content image-based screening of a signal transduction pathway inhibitor small-molecule library against highly pathogenic RNA viruses

artículo científico publicado en 2014

High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45.

artículo científico publicado en 2012

Histology, immunohistochemistry, and in situ hybridization reveal overlooked Ebola virus target tissues in the Ebola virus disease guinea pig model

artículo científico publicado en 2018

Homologous and heterologous protection of nonhuman primates by Ebola and Sudan virus-like particles

artículo científico publicado en 2015

Host response during Yersinia pestis infection of human bronchial epithelial cells involves negative regulation of autophagy and suggests a modulation of survival-related and cellular growth pathways.

artículo científico publicado en 2015

Human antibodies to bacterial superantigens and their ability to inhibit T-cell activation and lethality

artículo científico publicado en 2001

Human leukocyte antigen-DQ8 transgenic mice: a model to examine the toxicity of aerosolized staphylococcal enterotoxin B

artículo científico publicado en 2005

Humanized mice as a preclinical tool for infectious disease and biomedical research

artículo científico publicado en 2011

Humanlike immune response of human leukocyte antigen-DR3 transgenic mice to staphylococcal enterotoxins: a novel model for superantigen vaccines

scientific article published on 23 May 2002

ICTV Virus Taxonomy Profile: Filoviridae

artículo científico publicado en 2019

ICU-like Care of Nonhuman Primates with Ebola Virus Disease

artículo científico publicado en 2020

IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus

artículo científico publicado en 2013

Identification and pathological characterization of persistent asymptomatic Ebola virus infection in rhesus monkeys

artículo científico

Identification of RUVBL1 and RUVBL2 as Novel Cellular Interactors of the Ebola Virus Nucleoprotein

artículo científico publicado en 2019

Identification of a Small-molecule Antiviral with Broad-spectrum Application to Multiple, Lethal Virus Types

scientific article published in 2009

Identification of a coumarin-based antihistamine-like small molecule as an anti-filoviral entry inhibitor

artículo científico publicado en 2017

Identification of a small-molecule entry inhibitor for filoviruses

artículo científico publicado en 2011

Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

artículo científico publicado en 2015

Identification of an antioxidant small-molecule with broad-spectrum antiviral activity.

artículo científico publicado en 2011

Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen

artículo científico publicado en 2010

Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

artículo científico publicado en 2008

Identification of small molecule inhibitors of anthrax lethal factor

artículo científico publicado en 2004

Identifying the principal protective antigenic determinants of type A botulinum neurotoxin.

artículo científico publicado en 1998

Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses

artículo científico publicado en 2017

In vivo oligomerization and raft localization of Ebola virus protein VP40 during vesicular budding.

artículo científico publicado en 2003

Induced IL-10 splice altering approach to antiviral drug discovery.

artículo científico publicado en 2014

Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection

artículo científico publicado en 2005

Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin

artículo científico publicado en 2010

Inhibition of Ebola virus entry by a C-peptide targeted to endosomes

artículo científico publicado en 2011

Inhibition of human serum complement activity by diisopropylfluorophosphate and selected anticholinesterase insecticides.

artículo científico publicado en 1989

Inhibition of interleukin-2-stimulated enhancement of human natural killer (NK) cell activity by carbaryl, an anticholinesterase insecticide

artículo científico publicado el 1 de diciembre de 1992

Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons

artículo científico publicado en 2006

Integrated bioassays in microfluidic devices: botulinum toxin assays

artículo científico publicado en 2005

Integrating high-content imaging and chemical genetics to probe host cellular pathways critical for Yersinia pestis infection

artículo científico publicado en 2013

Intracellular conversion and in vivo dose response of favipiravir (T-705) in rodents infected with Ebola virus.

artículo científico publicado en 2017

Involvement of vacuolar protein sorting pathway in Ebola virus release independent of TSG101 interaction

artículo científico publicado en 2007

Iterative Structure-Based Peptide-Like Inhibitor Design against the Botulinum Neurotoxin Serotype A

artículo científico publicado en 2010

Key genomic changes necessary for an in vivo lethal mouse marburgvirus variant selection process

artículo científico publicado en 2011

L1000CDS2: LINCS L1000 characteristic direction signatures search engine

artículo científico publicado en 2016

Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization

artículo científico publicado en 2005

Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: implications for development of vaccines and therapeutics

artículo científico publicado en 2002

Lipid raft microdomains: a gateway for compartmentalized trafficking of Ebola and Marburg viruses

artículo científico publicado en 2002

Low potential for mechanical transmission of Ebola virus via house flies (Musca domestica).

artículo científico publicado en 2017

Machupo virus glycoprotein determinants for human transferrin receptor 1 binding and cell entry

artículo científico publicado en 2011

Macrophage-derived cell lines do not express proinflammatory cytokines after exposure to Bacillus anthracis lethal toxin

artículo científico publicado en 2001

Marburg Virus Disease

Marburg virus-like particles protect guinea pigs from lethal Marburg virus infection

artículo científico publicado en 2004

Marburgvirus hijacks nrf2-dependent pathway by targeting nrf2-negative regulator keap1.

artículo científico publicado en 2014

Mechanisms and consequences of ebolavirus-induced lymphocyte apoptosis

artículo científico publicado en 2010

Mechanisms of immunity in post-exposure vaccination against Ebola virus infection

artículo científico publicado en 2015

Modeling mosquito-borne and sexual transmission of Zika virus in an enzootic host, the African green monkey

scientific article published on 22 June 2020

Modulation of interleukin-2-driven proliferation of human large granular lymphocytes by carbaryl, an anticholinesterase insecticide.

artículo científico publicado en 1991

Molecular mechanisms of filovirus cellular trafficking.

artículo científico publicado en 2003

Monovalent virus-like particle vaccine protects guinea pigs and nonhuman primates against infection with multiple Marburg viruses

artículo científico publicado en 2008

Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors

artículo científico publicado en 2014

Mutational effects on protein folding stability and antigenicity: the case of streptococcal pyrogenic exotoxin A.

artículo científico publicado en 2003

NKp30-dependent cytolysis of filovirus-infected human dendritic cells.

artículo científico publicado en 2007

Neglected filoviruses

artículo científico publicado en 2016

Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon

artículo científico publicado en 2017

New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Post-intoxication Model.

artículo científico publicado en 2018

Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014.

artículo científico publicado en 2014

Nonhuman primates as models for the discovery and development of ebolavirus therapeutics

artículo científico publicado en 2011

Nonhuman transferrin receptor 1 is an efficient cell entry receptor for Ocozocoautla de Espinosa virus

artículo científico publicado en 2013

Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A.

artículo científico publicado en 2008

Novel Benzimidazole Inhibitors of Botulinum Neurotoxin/A Display Enzyme and Cell-Based Potency

artículo científico publicado en 2011

Novel broad-spectrum bis-(imidazolinylindole) derivatives with potent antibacterial activities against antibiotic-resistant strains

artículo científico publicado en 2009

Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity.

artículo científico publicado en 2003

Novel therapeutic uses and formulations of botulinum neurotoxins: a patent review (2012 - 2014).

artículo científico

Oligonucleotide antiviral therapeutics: antisense and RNA interference for highly pathogenic RNA viruses

scientific article published on 14 January 2008

Passive immunotherapy of Bacillus anthracis pulmonary infection in mice with antisera produced by DNA immunization

artículo científico publicado en 2006

Peptide conjugated phosphorodiamidate morpholino oligomers increase survival of mice challenged with Ames Bacillus anthracis.

artículo científico publicado en 2012

Persistence of zinc-binding bacterial superantigens at the surface of antigen-presenting cells contributes to the extreme potency of these superantigens as T-cell activators

artículo científico publicado en 2005

Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors

artículo científico publicado en 2018

Pharmacophore Refinement Guides the Rational Design of Nanomolar-Range Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease

artículo científico publicado en 2010

Pharmacophore-guided lead optimization: the rational design of a non-zinc coordinating, sub-micromolar inhibitor of the botulinum neurotoxin serotype a metalloprotease

artículo científico publicado en 2009

Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays

artículo científico publicado en 2015

Post-intoxication inhibition of botulinum neurotoxin serotype A within neurons by small-molecule, non-peptidic inhibitors

artículo científico publicado en 2011

Potent and broad-spectrum antibacterial activity of indole-based bisamidine antibiotics: synthesis and SAR of novel analogs of MBX 1066 and MBX 1090.

artículo científico publicado en 2013

Potentiation of inhaled staphylococcal enterotoxin B-induced toxicity by lipopolysaccharide in mice

scientific article published on 01 September 1996

Pre-positioned Outbreak Research: The Joint Medical Emerging Diseases Intervention Clinical Capability Experience in Uganda

scientific article published on 01 March 2020

Pre-symptomatic diagnosis and treatment of filovirus diseases

artículo científico publicado en 2015

Predictive systems biology approach to broad-spectrum, host-directed drug target discovery in infectious diseases

artículo científico publicado en 2013

Primary cultures of embryonic chicken neurons for sensitive cell-based assay of botulinum neurotoxin: implications for therapeutic discovery.

artículo científico publicado en 2007

Production and purification of a recombinant Staphylococcal enterotoxin B vaccine candidate expressed in Escherichia coli

artículo científico publicado en 2002

Protection against Staphylococcus aureus sepsis by vaccination with recombinant staphylococcal enterotoxin A devoid of superantigenicity

scientific article published on 01 October 1999

Protection against bacterial superantigen staphylococcal enterotoxin B by passive vaccination

artículo científico publicado en 2002

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.

artículo científico publicado en 2014

Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase

artículo científico publicado en 2016

Purified Bacillus anthracis lethal toxin complex formed in vitro and during infection exhibits functional and biological activity

artículo científico publicado en 2005

Quantitative Analysis of Repertoire-Scale Immunoglobulin Properties in Vaccine-Induced B-Cell Responses

artículo científico publicado en 2017

Rational design of small molecules as vaccine adjuvants.

artículo científico publicado en 2014

Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells

artículo científico publicado en 2013

Recent advances in botulinum neurotoxin inhibitor development.

artículo científico publicado en 2014

Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery

artículo científico publicado en 2014

Reduced expression of CD45 protein-tyrosine phosphatase provides protection against anthrax pathogenesis

artículo científico publicado en 2009

Reduced levels of protein tyrosine phosphatase CD45 protect mice from the lethal effects of Ebola virus infection

artículo científico publicado en 2009

Reemergence of monkeypox: prevalence, diagnostics, and countermeasures

artículo científico publicado en 2005

Reidentification of Ebola Virus E718 and ME as Ebola Virus/H.sapiens-tc/COD/1976/Yambuku-Ecran

artículo científico publicado en 2014

Repurposing potential of 1st generation H-specific antihistamines as anti-filovirus therapeutics

artículo científico publicado en 2018

Retrovirus-Based Surrogate Systems for BSL-2 High-Throughput Screening of Antivirals Targeting BSL-3/4 Hemorrhagic Fever-Causing Viruses

artículo científico publicado en 2018

Ribavirin has a Demonstrable Effect on Crimean-Congo Hemorrhagic Fever Viral Populations and Viral Load during Patient Treatment.

artículo científico publicado en 2018

Role of Antibodies in Protection Against Ebola Virus in Nonhuman Primates Immunized With Three Vaccine Platforms

scholarly article by Kelly L Warfield et al published 22 November 2018 in Journal of Infectious Diseases

Role of Rodents and Bats in Human Viral Hemorrhagic Fevers

Role of natural killer cells in innate protection against lethal ebola virus infection

artículo científico publicado en 2004

SRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neurons

artículo científico publicado en 2015

Searching for Therapeutics Against Botulinum Neurotoxins: A True Challenge for Drug Discovery.

artículo científico publicado en 2016

Second generation of diazachrysenes: Protection of Ebola virus infected mice and mechanism of action

artículo científico publicado en 2018

Second generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malaria

artículo científico publicado en 2014

Shedding light on filovirus infection with high-content imaging

artículo científico publicado en 2012

Sizing the Bacillus anthracis PA63 channel with nonelectrolyte poly(ethylene glycols)

artículo científico publicado en 2008

Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses

artículo científico publicado en 2013

Sorafenib impedes Rift Valley fever virus egress by inhibiting Valosin-containing protein function in the cellular secretory pathway

artículo científico publicado en 2017

Sphingosine kinase 2 is a chikungunya virus host factor co-localized with the viral replication complex

artículo científico publicado en 2015

Standardization of the filovirus plaque assay for use in preclinical studies

artículo científico publicado en 2012

Staphylococcal enterotoxin A and toxic shock syndrome toxin compete with CD4 for human major histocompatibility complex class II binding.

artículo científico publicado en 1995

Staphylococcal enterotoxins A and B share a common structural motif for binding class II major histocompatibility complex molecules

artículo científico publicado en 1995

Superantigen vaccines: a comparative study of genetically attenuated receptor-binding mutants of staphylococcal enterotoxin A

artículo científico publicado en 1996

Synthesis and biological evaluation of botulinum neurotoxin a protease inhibitors

artículo científico publicado en 2010

T-705 induces lethal mutagenesis in Ebola and Marburg populations in macaques

artículo científico publicado en 2019

T-cell-dependent mechanisms promote Ebola VLP-induced antibody responses, but are dispensable for vaccine-mediated protection

artículo científico

Taxonomy of the order Mononegavirales: second update 2018

scientific article published on 01 April 2019

Taxonomy of the order Mononegavirales: update 2016

artículo científico publicado en 2016

Taxonomy of the order Mononegavirales: update 2017.

artículo científico publicado en 2017

Taxonomy of the order Mononegavirales: update 2018.

artículo científico publicado en 2018

Taxonomy of the order Mononegavirales: update 2019

artículo científico publicado en 2019

The C terminus of the catalytic domain of type A botulinum neurotoxin may facilitate product release from the active site

artículo científico publicado en 2013

The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines

scientific article published on 05 August 2020

The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines

scientific article published on 26 November 2020

The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus

scientific article published on 08 August 2019

The Impact of Regulations, Safety Considerations and Physical Limitations on Research Progress at Maximum Biocontainment ⬇️

artículo científico publicado el 1 de diciembre de 2012

The International Code of Virus Classification and Nomenclature (ICVCN): proposal for text changes for improved differentiation of viral taxa and viruses

artículo científico publicado en 2013

The International Code of Virus Classification and Nomenclature (ICVCN): proposal to delete Rule 3.41.

artículo científico publicado en 2012

The evolving field of biodefence: therapeutic developments and diagnostics

artículo científico publicado en 2005

The osmolyte trimethylamine N-oxide (TMAO) increases the proteolytic activity of botulinum neurotoxin light chains A, B, and E: implications for enhancing analytical assay sensitivity

artículo científico publicado en 2010

The rapidly advancing field of biodefense benefits many other, critical public health concerns

artículo científico publicado en 2005

The synthesis of 2,5-bis(4-amidinophenyl)thiophene derivatives providing submicromolar-range inhibition of the botulinum neurotoxin serotype A metalloprotease

artículo científico publicado en 2012

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

artículo científico publicado en 2016

Therapeutic potential of the heme oxygenase-1 inducer hemin against Ebola virus infection

artículo científico publicado en 2016

Therapeutics for filovirus infection: traditional approaches and progress towards in silico drug design

artículo científico publicado en 2012

Three-dimensional database mining identifies a unique chemotype that unites structurally diverse botulinum neurotoxin serotype A inhibitors in a three-zone pharmacophore.

artículo científico publicado en 2008

Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors

artículo científico publicado en 2011

Time-lapse confocal imaging of development of Bacillus anthracis in macrophages

artículo científico publicado en 2004

Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation

artículo científico publicado en 2014

Transcriptome analysis of human immune responses following live vaccine strain (LVS) Francisella tularensis vaccination

artículo científico publicado en 2007

Treatment of highly pathogenic filovirus infections using advanced antisense technology

Treatment-focused Ebola trials, supportive care and future of filovirus care.

artículo científico publicado en 2017

TrkA in vivo function is negatively regulated by ubiquitination

artículo científico publicado en 2014

United States FDA's emergency use authorization of Ebola virus diagnostics: current impact and lessons for the future

artículo científico publicado en 2015

VP35 knockdown inhibits Ebola virus amplification and protects against lethal infection in mice

artículo científico publicado en 2006

Vaccine adjuvant uses of poly-IC and derivatives

artículo científico publicado en 2014

Validation of the Filovirus Plaque Assay for Use in Preclinical Studies

artículo científico publicado en 2016

Viral Hemorrhagic Fevers

Viral diversity and clonal evolution from unphased genomic data.

artículo científico publicado en 2014

Virulence of Marburg Virus Angola Compared to Mt. Elgon (Musoke) in Macaques: A Pooled Survival Analysis

scientific article published on 21 November 2018

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA

artículo científico publicado en 2013

Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

artículo científico publicado en 2013

Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

artículo científico publicado en 2012

Virus-Like Particle Vaccination Protects Nonhuman Primates from Lethal Aerosol Exposure with Marburgvirus (VLP Vaccination Protects Macaques against Aerosol Challenges).

artículo científico publicado en 2016

Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection

artículo científico publicado en 2015

Virus-like particles exhibit potential as a pan-filovirus vaccine for both Ebola and Marburg viral infections

artículo científico publicado en 2005

Will There Be a Cure for Ebola?

artículo científico publicado en 2016

Zika Virus Infection in Syrian Golden Hamsters and Strain 13 Guinea Pigs

artículo científico publicado en 2018

siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection

artículo científico publicado en 2016

“Venezuelan” Hemorrhagic Fever

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