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Lista de obras de Tim Spector

2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio

artículo científico publicado en 2017

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

72: A Genome Wide Association Study (GWAS) from a global cohort identifies common variants in FSHB and SMAD3 driving spontaneous human dizygotic twinning

A Comparison of Heritability Estimates by Classical Twin Modeling and Based on Genome-Wide Genetic Relatedness for Cardiac Conduction Traits

artículo científico publicado en 2017

A DNA methylation biomarker of alcohol consumption.

artículo científico publicado en 2016

A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation

artículo científico publicado en 2021

A General Factor of Personality: Evidence from the HEXACO Model and a Measure of Trait Emotional Intelligence

article

A Large-Scale Population-Based Analysis of Common Genetic Variation in the Thyroid Hormone Receptor Alpha Locus and Bone

scholarly article by Marco Medici et al published February 2012 in Thyroid

A Letter to the Editor on the Article by Burri et al

artículo científico publicado en 2010

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population

artículo científico publicado en 2015

A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.

artículo científico publicado en 2007

A Randomized Controlled Trial of Vitamin D Supplementation on Preventing Postmenopausal Bone Loss and Modifying Bone Metabolism Using Identical Twin Pairs

artículo científico publicado en 2000

A UK case-control study on the effect of parity and the oral contraceptive pill on the development of rheumatoid arthritis

article

A case-control study of oral contraceptive use in women with rheumatoid arthritis and their unaffected sisters

artículo científico publicado en 1989

A common genetic factor underlies hypertension and other cardiovascular disorders

artículo científico publicado en 2004

A common variant in the telomerase RNA component is associated with short telomere length

artículo científico publicado en 2010

A comparative study between corresponding structural geometric variables using 2 commonly implemented hip structural analysis algorithms applied to dual-energy X-ray absorptiometry images

artículo científico publicado en 2009

A comparison of radiographic anatomic axis knee alignment measurements and cross-sectional associations with knee osteoarthritis

artículo científico publicado en 2015

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample

artículo científico publicado en 2011

A cotwin control study of the relationship between hip osteoarthritis and bone mineral density

artículo científico publicado en 2000

A discordant monozygotic twin approach to testing environmental influences on sexual dysfunction in women.

artículo científico publicado en 2013

A first update on mapping the human genetic architecture of COVID-19

artículo científico publicado en 2022

A genome-screen of a large twin cohort reveals linkage for quantitative ultrasound of the calcaneus to 2q33-37 and 4q12-21.

artículo científico publicado en 2003

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

artículo científico publicado en 2012

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25.

artículo científico publicado en 2010

A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length.

scientific article published on 08 April 2009

A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.

artículo científico publicado en 2010

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22

scientific journal article

A genome-wide association study identifies five loci influencing facial morphology in Europeans

artículo científico publicado en 2012

A genome-wide association study of early menopause and the combined impact of identified variants

artículo científico publicado en 2013

A genome-wide association study of female sexual dysfunction

scientific journal article

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

artículo científico publicado en 2012

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

artículo científico publicado en 2009

A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium.

artículo científico publicado en 2009

A genome-wide linkage scan for age at menarche in three populations of European descent

artículo científico publicado en 2008

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

artículo científico publicado en 2009

A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection

artículo científico publicado en 2011

A genome-wide perspective of genetic variation in human metabolism

artículo científico publicado en 2009

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

artículo científico publicado en 2011

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB

artículo científico publicado en 2009

A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units

artículo científico publicado en 2016

A higher alkaline dietary load is associated with greater indexes of skeletal muscle mass in women

artículo científico publicado en 2012

A locus on chromosome 1p36 is associated with thyrotropin and thyroid function as identified by genome-wide association study

artículo científico publicado en 2010

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

artículo científico publicado en 2015

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

artículo científico publicado en 2014

A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis

artículo científico publicado en 2010

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

artículo científico publicado en 2013

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

A metagenome-wide association study of gut microbiota in asthma in UK adults

artículo científico publicado en 2018

A method for determining skeletal lengths from DXA images

artículo científico publicado en 2007

A multivariate twin study of female sexual dysfunction.

artículo científico publicado en 2012

A mutation in COL9A1 causes multiple epiphyseal dysplasia: further evidence for locus heterogeneity

artículo científico publicado en 2001

A new 5-lipoxygenase inhibitor seems to be safe and effective for the treatment of osteoarthritis

artículo científico publicado en 2009

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

artículo científico publicado en 2009

A population study of the screening potential of assessment of trabecular pattern of the femoral neck (Singh index): the Chingford Study

artículo científico publicado en 1995

A prediction model to prioritize individuals for SARS-CoV-2 test built from national symptom surveys

artículo científico publicado en 2020

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A probabilistic model of biological ageing of the lungs for analysing the effects of smoking, asthma and COPD

artículo científico publicado en 2013

A randomised controlled trial of the effect of hormone replacement therapy on disease activity in postmenopausal rheumatoid arthritis

artículo científico publicado en 1994

A randomized trial of testosterone therapy in males with rheumatoid arthritis

artículo científico publicado en 1996

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

artículo científico publicado en 2014

A reference map of potential determinants for the human serum metabolome

artículo científico publicado en 2020

A reference panel of 64,976 haplotypes for genotype imputation

artículo científico publicado en 2016

A response to Videman et al., “Challenging the cumulative injury model: positive effects of greater body mass on disc degeneration”

article

A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype

artículo científico publicado en 2012

A study of pathophysiological factors associated with gastro-esophageal reflux disease in twins discordant for gastro-esophageal reflux symptoms.

artículo científico publicado en 2013

A study of possible associations between single nucleotide polymorphisms in the estrogen receptor 2 gene and female sexual desire.

artículo científico publicado en 2014

A survey of UK public interest in internet-based personal genome testing

artículo científico publicado en 2010

A susceptibility locus for myopia in the normal population is linked to the PAX6 gene region on chromosome 11: a genomewide scan of dizygotic twins

artículo científico publicado en 2004

A systematic evaluation of 151 candidate genes for their association with osteoporosis and osteoporotic fracture in a meta-analysis of genome-wide association data

article

A twin approach to unraveling epigenetics

artículo científico publicado en 2011

A twin study of body dysmorphic concerns

artículo científico publicado en 2011

A twin study of mitochondrial DNA polymorphisms shows that heteroplasmy at multiple sites is associated with mtDNA variant 16093 but not with zygosity

artículo científico publicado en 2011

A variant in MCF2L is associated with osteoarthritis

artículo científico publicado en 2011

ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins

artículo científico publicado en 2016

AMP-kinase alpha2 subunit gene PRKAA2 variants are associated with total cholesterol, low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol in normal women

artículo científico publicado en 2006

Abdominal Aortic Calcification Detection Using Dual-Energy X-Ray Absorptiometry: Validation Study in Healthy Women Compared to Computed Tomography

artículo científico publicado el 14 de febrero de 2013

Accelerated aortic imaging using small field of view imaging and electrocardiogram-triggered quadruple inversion recovery magnetization preparation

artículo científico publicado en 2011

Accessible data curation and analytics for international-scale citizen science datasets

scientific article published on 22 November 2021

Acetaminophen (Paracetamol) Use Modifies the Sulfation of Sex Hormones

artículo científico publicado en 2018

Acne and Telomere Length: A New Spectrum Between Senescence and Apoptosis Pathways

artículo científico publicado en 2016

Activation markers of coagulation and fibrinolysis in twins: heritability of the prethrombotic state

scientific article published on 01 February 2002

Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity.

artículo científico publicado en 2008

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

artículo científico publicado en 2015

Adiposity-Dependent Regulatory Effects on Multi-tissue Transcriptomes

artículo científico publicado en 2016

Adjusted sequence kernel association test for rare variants controlling for cryptic and family relatedness.

artículo científico publicado en 2013

Affective responses to sweet products and sweet solution in British and Finnish adults

article

Age differences in genetic and environmental variations in stress-coping during adulthood: a study of female twins

artículo científico publicado en 2012

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

artículo científico publicado en 2015

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort

artículo científico publicado en 2017

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort

article

Aging Trajectories in Different Body Systems Share Common Environmental Etiology: The Healthy Aging Twin Study (HATS).

artículo científico publicado en 2016

Alcohol-induced metabolomic differences in humans

artículo científico publicado en 2013

Allelic variation at the interleukin-1 receptor antagonist gene is associated with early postmenopausal bone loss at the spine

artículo científico publicado el 1 de octubre de 1998

American Gut: an Open Platform for Citizen Science Microbiome Research

article

Amino Acid Intakes Are Associated With Bone Mineral Density and Prevalence of Low Bone Mass in Women: Evidence From Discordant Monozygotic Twins

artículo científico publicado en 2015

Amino Acid Intakes Are Inversely Associated with Arterial Stiffness and Central Blood Pressure in Women

artículo científico publicado en 2015

An Automatic 3D Facial Landmarking Algorithm Using 2D Gabor Wavelets.

artículo científico publicado en 2015

An Investigation Into Physical Frailty as a Link Between the Gut Microbiome and Cognitive Health

article

An Investigation of Unique and Shared Gene Effects on Speed of Sound and Bone Density Using Axial Transmission Quantitative Ultrasound and DXA in Twins

article

An analysis of which anti-osteoporosis therapeutic regimen would improve compliance in a population of elderly adults

artículo científico publicado en 2007

An atlas of genetic influences on human blood metabolites

artículo científico publicado en 2014

An epidemiological survey of post-coital psychological symptoms in a UK population sample of female twins.

artículo científico publicado en 2011

An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

artículo científico publicado en 2014

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits

artículo científico publicado en 2010

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.

artículo científico publicado en 2019

An obesogenic postnatal environment is more important than the fetal environment for the development of adult adiposity: a study of female twins

artículo científico publicado en 2009

An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker

artículo científico publicado en 2015

An unsupervised learning approach to identify novel signatures of health and disease from multimodal data

scientific article published on 10 January 2020

Analysis of antibody binding specificities in twin and SNP-genotyped cohorts reveals that antiviral antibody epitope selection is a heritable trait

artículo científico publicado en 2022

Androgen status of females with RA

artículo científico publicado en 1987

Anosmia and other SARS-CoV-2 positive test-associated symptoms, across three national, digital surveillance platforms as the COVID-19 pandemic and response unfolded: an observation study

artículo científico publicado en 2020

Anosmia, ageusia, and other COVID-19-like symptoms in association with a positive SARS-CoV-2 test, across six national digital surveillance platforms: an observational study

artículo científico publicado en 2021

Anxiety and depression symptoms after COVID-19 infection: results from the COVID Symptom Study app

artículo científico publicado en 2021

Are Twins and Singletons Comparable? A Study of Disease-related and Lifestyle Characteristics in Adult Women

article by Toby Andrew et al published December 2001 in Twin Research and Human Genetics

Are certain HLA haplotypes responsible for low testosterone levels in males?

artículo científico publicado en 1989

Are intra-articular injections of hylan more effective than injections of hyaluronic acid for knee osteoarthritis?

scientific article published on 01 July 2008

Are slow-acting antirheumatic drugs being given earlier in rheumatoid arthritis?

artículo científico publicado en 1988

Are twins and singletons comparable? A study of disease-related and lifestyle characteristics in adult women

artículo científico publicado en 2001

Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 Diabetes

artículo científico publicado en 2020

Arterial Stiffening Relates to Arterial Calcification But Not to Noncalcified Atheroma in Women

artículo científico publicado el 29 de marzo de 2011

Arterial stiffening is a heritable trait associated with arterial dilation but not wall thickening: a longitudinal study in the twins UK cohort

artículo científico publicado en 2018

Ascorbic acid metabolites are involved in intraocular pressure control in the general population

artículo científico publicado en 2018

Assessment of age-related changes in heritability and IGF-1 gene effect on circulating IGF-1 levels

artículo científico publicado en 2014

Assessment of gene-by-sex interaction effect on bone mineral density

artículo científico publicado en 2012

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

artículo científico publicado en 2014

Assessment of osteopenia from spine radiographs using two different methods: the Chingford Study

artículo científico publicado en 1996

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study

artículo científico publicado en 2017

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

artículo científico publicado en 2010

Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activity

Association between DHEAS and Bone Loss in Postmenopausal Women: A 15-Year Longitudinal Population-Based Study

artículo científico publicado el 26 de julio de 2011

Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population

artículo científico publicado en 2007

Association between Physical Activity Energy Expenditure and Continuous Glucose Monitor-Derived Metrics: Data from the ZOE PREDICT 1 Study

Association between a variation in the phosphodiesterase 4D gene and bone mineral density

artículo científico publicado en 2005

Association between a variation inLRCH1 and knee osteoarthritis: A genome-wide single-nucleotide polymorphism association study using DNA pooling

artículo científico publicado en 2006

Association between birth weight and adult blood pressure in twins: historical cohort study

artículo científico publicado en 1999

Association between cartilage and bone biomarkers and incidence of radiographic knee osteoarthritis (RKOA) in UK females: a prospective study

artículo científico publicado en 2013

Association between metabolic factors and knee osteoarthritis in women: the Chingford Study

artículo científico publicado el 1 de junio de 1995

Association of Cross-Sectional and Longitudinal Change in Arterial Stiffness With Gene Expression in the Twins UK Cohort

artículo científico publicado en 2015

Association of FTO gene variants with body composition in UK twins

artículo científico publicado en 2012

Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.

artículo científico publicado en 2010

Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes

scientific article published on 14 September 2008

Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants

artículo científico publicado en 2014

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent

artículo científico publicado en 2013

Association of birth weight with osteoporosis and osteoarthritis in adult twins

artículo científico publicado en 2003

Association of common JAK2 variants with body fat, insulin sensitivity and lipid profile

artículo científico publicado en 2008

Association of early osteoarthritis of the knee with a Taq I polymorphism of the vitamin D receptor gene

artículo científico publicado en 1997

Association of interleukin-6 gene polymorphisms with hand osteoarthritis and hand osteoporosis

artículo científico publicado en 2014

Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women

scientific article published on 31 July 2018

Association of pain with radiological changes in different compartments and views of the knee joint

artículo científico publicado en 1996

Association of polymorphism at the type I collagen (COL1A1) locus with reduced bone mineral density, increased fracture risk, and increased collagen turnover

artículo científico publicado en 1999

Association of social distancing and masking with risk of COVID-19

scientific article published on 13 November 2020

Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome

artículo científico publicado en 2015

Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations

artículo científico publicado en 2008

Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans.

artículo científico publicado en 2017

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

artículo científico publicado en 2014

Association study of candidate genes for the prevalence and progression of knee osteoarthritis

artículo científico publicado en 2004

Associations between UK tap water and gut microbiota composition suggest the gut microbiome as a potential mediator of health differences linked to water quality

artículo científico publicado en 2020

Associations between branched chain amino acid intake and biomarkers of adiposity and cardiometabolic health independent of genetic factors: A twin study

scientific article published on 23 August 2016

Attitudes towards human reproductive cloning, assisted reproduction and gene selection: a survey of 4600 British twins

article

Attributes and predictors of Long-COVID: analysis of COVID cases and their symptoms collected by the Covid Symptoms Study App

report published in 2020

Attributes and predictors of Long-COVID: analysis of COVID cases and their symptoms collected by the Covid Symptoms Study App

artículo científico publicado en 2020

Attributes and predictors of long COVID

Author Correction: Attributes and predictors of long COVID

artículo científico publicado en 2021

Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability

artículo científico publicado en 2019

Authors' reply to Mawer and Wilcox and Mullish and Williams

artículo científico publicado en 2015

Autosomal genetic control of human gene expression does not differ across the sexes

artículo científico publicado en 2016

Bacon rashers, statistics, and controversy

scientific article published on 14 October 2019

Beta 3-adrenergic receptor gene polymorphisms and determination of adiposity and fat distribution in normal female twins

artículo científico publicado en 1997

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach

artículo científico publicado en 2013

Biomarkers in osteoarthritis

artículo científico publicado en 2008

Birthweight, vitamin D receptor genotype and the programming of osteoporosis.

artículo científico publicado en 2001

Bisphosphonates: potential therapeutic agents for disease modification in osteoarthritis

artículo científico publicado en 2003

Bivariate genetic modelling of the response to an oral glucose tolerance challenge: a gene x environment interaction approach

artículo científico publicado en 2009

Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals

artículo científico publicado en 2020

Blood, urine and faecal metabolite profiles in the study of adult renal disease

artículo científico

Blue poo: impact of gut transit time on the gut microbiome using a novel marker

artículo científico publicado en 2021

Body odor similarity in noncohabiting twins

artículo científico publicado en 2005

Body site-specific genetic effects influence naevus count distribution in women

artículo científico publicado en 2019

Bone mineral density of patients with chronic plaque psoriasis

scientific article published on 01 July 2001

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

artículo científico publicado en 2008

Bone structural effects of variation in the TNFRSF1B gene encoding the tumor necrosis factor receptor 2

article

Building an International Consortium for Tracking Coronavirus Health Status

artículo científico publicado en 2020

Building an international consortium for tracking coronavirus health status

artículo científico publicado en 2020

CD36 gene promoter polymorphisms are associated with low density lipoprotein-cholesterol in normal twins and after a low-calorie diet in obese subjects

artículo científico publicado en 2008

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

artículo científico publicado en 2017

Can Your Microbiome Tell You What to Eat?

artículo científico publicado en 2015

Can biochemical markers predict bone loss at the hip and spine?: a 4-year prospective study of 141 early postmenopausal women

artículo científico publicado en 1996

Can the WHO definition of osteoporosis be applied to multi-site axial transmission quantitative ultrasound?

article

Cancer and Risk of COVID-19 Through a General Community Survey

artículo científico publicado en 2020

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

artículo científico publicado en 2013

Central corneal thickness is highly heritable: the twin eye studies.

artículo científico publicado en 2005

Central retinal thickness is positively correlated with macular pigment optical density.

artículo científico publicado en 2005

Challenges and opportunities for better nutrition science-an essay by Tim Spector and Christopher Gardner

artículo científico publicado en 2020

Change in body mass index during middle age affects risk of total knee arthoplasty due to osteoarthritis: a 19-year prospective study of 1003 women.

artículo científico publicado en 2011

Changes in symptomatology, re-infection and transmissibility associated with SARS-CoV-2 variant B.1.1.7: an ecological study

Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study

artículo científico publicado en 2021

Characterisation of Fasting and Postprandial NMR Metabolites: Insights from the ZOE PREDICT 1 Study

artículo científico publicado en 2023

Characterisation, procedures and heritability of acute dietary intake in the Twins UK cohort: an observational study

artículo científico publicado en 2022

Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants

artículo científico publicado en 2015

Characterizing Blood Metabolomics Profiles Associated with Self-Reported Food Intakes in Female Twins.

artículo científico publicado en 2016

Choline-stabilized orthosilicic acid supplementation as an adjunct to calcium/vitamin D3 stimulates markers of bone formation in osteopenic females: a randomized, placebo-controlled trial

artículo científico publicado en 2008

Choosing the best method for radiological assessment of patellofemoral osteoarthritis

artículo científico publicado en 1996

Cigarette smoking and risk of osteoarthritis in women in the general population: the Chingford study

artículo científico publicado en 1993

Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation

artículo científico publicado en 2014

Circulating Levels of the Short-Chain Fatty Acid Acetate Mediate the Effect of the Gut Microbiome on Visceral Fat

artículo científico publicado en 2021

Circulating Proteomic Signatures of Chronological Age.

artículo científico publicado en 2014

Circulating levels of antioxidant vitamins correlate with better lung function and reduced exposure to ambient pollution

artículo científico publicado en 2015

Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversity

scientific article published on 29 April 2019

Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations

artículo científico publicado en 2018

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

artículo científico publicado en 2009

Clinical signs of early osteoarthritis: reproducibility and relation to x ray changes in 541 women in the general population

artículo científico publicado en 1991

Codiversification of gut microbiota with humans

artículo científico publicado en 2022

Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes

artículo científico publicado en 2012

Cognitive change in older women using a computerised battery: a longitudinal quantitative genetic twin study

scientific article published on 30 August 2013

Cohort Profile: TwinsUK and healthy ageing twin study

artículo científico publicado en 2013

Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture

artículo científico publicado en 2009

Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci

artículo científico publicado en 2007

Combined genome scans for body stature in 6602 European twins: evidence for common Caucasian loci

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common STAT3 variants are not associated with obesity or insulin resistance in female twins

artículo científico publicado en 2007

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

artículo científico publicado en 2010

Common genetic factors among sexual orientation, gender nonconformity, and number of sex partners in female twins: implications for the evolution of homosexuality.

artículo científico publicado en 2015

Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness

artículo científico publicado en 2010

Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis

artículo científico publicado en 2010

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies

artículo científico publicado en 2009

Common polymorphisms in SOCS3 are not associated with body weight, insulin sensitivity or lipid profile in normal female twins

artículo científico publicado en 2006

Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro

artículo científico publicado en 2009

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

artículo científico publicado en 2010

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program

artículo científico publicado en 2012

Common variants in the region around Osterix are associated with bone mineral density and growth in childhood

artículo científico publicado en 2009

Common variants near TERC are associated with mean telomere length

artículo científico publicado en 2010

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

artículo científico publicado en 2017

Comparison of serum FSH and Inhibin B levels between adult male dizygotic and monozygotic twins

artículo científico publicado en 2005

Comparison of three methods of intraocular pressure measurement and their relation to central corneal thickness

artículo científico publicado en 2010

Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal

artículo científico publicado en 2013

Conducting metagenomic studies in microbiology and clinical research

artículo científico publicado en 2018

Consumption of Stilbenes and Flavonoids is Linked to Reduced Risk of Obesity Independently of Fiber Intake

artículo científico publicado en 2020

Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins

artículo científico publicado en 2016

Contribution of putative genetic factors and candidate gene variants to inter-individual variation of circulating fractalkine (CX3CL1) levels in a large UK twins' sample

artículo científico publicado en 2012

Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis

scientific article published on 13 July 2013

Copy number variation of the APC gene is associated with regulation of bone mineral density

artículo científico publicado en 2012

Correction to: Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota

artículo científico publicado en 2018

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: Identification of PLCL1 Gene for Hip Bone Size Variation in Females in a Genome-Wide Association Study

artículo científico publicado en 2009

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Correction: Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

scientific article published on 05 December 2019

Corrigendum to “A genome-wide association study identifies a common variant near the GPR22 gene as a new locus involved in prevalence and progression of osteoarthritis” [Bone. 44S2 (2009) S224]

article

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

artículo científico publicado en 2016

Could food act as personalized medicine for chronic disease?

artículo científico publicado en 2017

Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma

artículo científico publicado en 2022

Current smoking and COVID-19 risk: results from a population symptom app in over 2.4 million people

artículo científico publicado en 2021

Current tobacco smoking and risk from COVID-19: results from a population symptom app in over 2.4 million people

artículo científico publicado en 2020

DCAF4, a novel gene associated with leucocyte telomere length

artículo científico publicado en 2015

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

artículo científico publicado en 2017

DNA Methylation Changes in the IGF1R Gene in Birth Weight Discordant Adult Monozygotic Twins

artículo científico publicado en 2015

DNA methylation and body-mass index: a genome-wide analysis

artículo científico publicado en 2014

DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

artículo científico publicado en 2017

DNA methylation of lipid-related genes affects blood lipid levels

scientific article published on 12 January 2015

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

artículo científico publicado en 2012

DNA methylation studies using twins: what are they telling us?

artículo científico publicado en 2012

DNA methylation-based measures of biological age: meta-analysis predicting time to death

artículo científico publicado en 2016

Decreased immunoglobulin G core fucosylation, a player in antibody-dependent cell-mediated cytotoxicity, is associated with autoimmune thyroid diseases

artículo científico publicado en 2020

Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening

artículo científico publicado en 2015

Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.

artículo científico publicado en 2018

Deficiency of Prebiotic Fibre and Insufficient Signalling Through Gut Metabolite Sensing Receptors Leads to Cardiovascular Disease

artículo científico publicado en 2020

Defining osteoarthritis of the hand for epidemiological studies: the Chingford Study

artículo científico publicado en 1994

Defining the genetic control of human blood plasma N-glycome using genome-wide association study

Defining the genetic control of human blood plasma N-glycome using genome-wide association study

scientific article published on 01 June 2019

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Definition and epidemiology of osteoarthritis of the hand: a review

artículo científico publicado en 2000

Definition of osteoarthritis of the knee for epidemiological studies

artículo científico publicado en 1993

Definitive Zygosity Scores in the Peas in the Pod Questionnaire is a Sensitive and Accurate Assessment of the Zygosity of Adult Twins

Depressed levels of dehydroepiandrosterone sulphate in postmenopausal women with rheumatoid arthritis but no relation with axial bone density

artículo científico publicado en 1993

Design and conduct of clinical trials in patients with osteoarthritis of the hand: recommendations from a task force of the Osteoarthritis Research Society International.

artículo científico publicado en 2006

Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application

artículo científico publicado en 2020

Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application: a prospective, observational study

scientific article published on 03 December 2020

Detecting SARS-CoV-2 at point of care: Preliminary data comparing Loop-mediated isothermal amplification (LAMP) to PCR

artículo científico publicado en 2020

Detecting SARS-CoV-2 at point of care: preliminary data comparing loop-mediated isothermal amplification (LAMP) to polymerase chain reaction (PCR)

artículo científico publicado en 2020

Detection of stable community structures within gut microbiota co-occurrence networks from different human populations

artículo científico publicado en 2018

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

artículo científico publicado en 2020

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Determinants of pressure pain threshold in adult twins: evidence that shared environmental influences predominate

artículo científico publicado en 1997

Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study

artículo científico publicado en 2007

Diagnostic value of cutaneous manifestation of SARS‐CoV‐2 infection*

artículo científico publicado en 2021

Diet and bone mineral density study in postmenopausal women from the TwinsUK registry shows a negative association with a traditional English dietary pattern and a positive association with wine

artículo científico publicado en 2011

Diet quality and risk and severity of COVID-19: a prospective cohort study

artículo científico publicado en 2021

Dietary Fat and Fatty Acid Profile Are Associated with Indices of Skeletal Muscle Mass in Women Aged 18–79 Years

artículo científico publicado en 2014

Dietary Influence on Systolic and Diastolic Blood Pressure in the TwinsUK Cohort

scientific article published on 17 July 2020

Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.

artículo científico publicado en 2015

Dietary garlic and hip osteoarthritis: evidence of a protective effect and putative mechanism of action

artículo científico publicado en 2010

Dietary patterns and heritability of food choice in a UK female twin cohort.

artículo científico publicado en 2007

Dietary supplements during the COVID-19 pandemic: insights from 1.4M users of the COVID Symptom Study app - a longitudinal app-based community survey

artículo científico publicado en 2020

Differences between race and sex in measures of hip morphology: a population-based comparative study

scientific article published on 13 December 2019

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts

artículo científico publicado en 2017

Differential DNA Methylation in Monozygotic Twins Discordant for Female Sexual Functioning.

artículo científico publicado en 2017

Differential associations between a priori diet quality scores and markers of cardiovascular health in women: cross sectional analyses from Twins UK

scientific article published on 10 December 2020

Differential effects of hormone replacement therapy on bone mineral density and axial transmission ultrasound measurements in cortical bone

article

Differential methylation of the TRPA1 promoter in pain sensitivity

artículo científico publicado en 2014

Digital quantification of human eye color highlights genetic association of three new loci

artículo científico publicado en 2010

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of novel heart rate-associated loci using the Exome Chip

artículo científico publicado en 2017

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Disentangling post-vaccination symptoms from early COVID-19

artículo científico publicado en 2021

Disentangling the genetics of lean mass

article

Dissecting the Role of the Gut Microbiota and Diet on Visceral Fat Mass Accumulation (OR31-07-19)

artículo científico publicado en 2019

Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation

scientific article published on 05 July 2019

Do current regimes of hormone replacement therapy protect against subsequent fractures?

artículo científico publicado el 1 de septiembre de 1992

Do gene-environment interactions influence fasting plasma lipids? A study of twins.

artículo científico publicado en 2004

Does More Schooling Improve Health Outcomes and Health Related Behaviors? Evidence from U.K. Twins

artículo científico publicado en 2013

Does education attenuate the genetic risk of obesity? Evidence from U.K. Twins

scientific article published on 13 September 2018

Does estrogen replacement therapy protect against rheumatoid arthritis?

artículo científico publicado el 1 de octubre de 1991

Does obesity predict knee pain over fourteen years in women, independently of radiographic changes?

artículo científico publicado en 2011

Does the negative association between rheumatoid arthritis and schizophrenia provide clues to the aetiology of rheumatoid arthritis?

scientific article published on 01 August 1987

Doxycycline and osteoarthritis: what does it show us?

artículo científico publicado en 2006

Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases

artículo científico publicado en 2020

EPHA2 is associated with age-related cortical cataract in mice and humans

artículo científico publicado en 2009

Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration

scientific article published on 22 November 2019

Effect of ONO-5334 on bone mineral density and biochemical markers of bone turnover in postmenopausal osteoporosis: 2-year results from the OCEAN study.

artículo científico publicado en 2014

Effect of Postprandial Glucose Dips on Hunger and Energy Intake in 1102 Subjects in US and UK: The PREDICT 1 Study

Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus.

artículo científico publicado en 2015

Effect of hormone replacement therapy on bone mass in rheumatoid arthritis patients treated with and without steroids

artículo científico publicado en 1994

Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]

artículo científico publicado en 2005

Effect of spinal osteophytosis on bone mineral density measurements in vertebral osteoporosis

artículo científico publicado en 1993

Effective measurement of knee alignment using AP knee radiographs

artículo científico publicado en 2008

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

artículo científico publicado en 2019

Effects of Environmental Factors on Severity and Mortality of COVID-19

artículo científico publicado en 2020

Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial

artículo científico publicado en 2024

Effects of age on genetic influence on bone loss over 17 years in women: the Healthy Ageing Twin Study (HATS).

artículo científico publicado en 2012

Effects of cyclical etidronate combined with calcitriol versus cyclical etidronate alone on spine and femoral neck bone mineral density in postmenopausal osteoporotic women

artículo científico publicado el 1 de junio de 1998

Effects of environmental factors on severity and mortality of COVID-19

artículo científico publicado en 2020

Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial

artículo científico publicado en 2008

Effects of statins on the immunoglobulin G glycome

artículo científico

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial

artículo científico publicado en 2013

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms

artículo científico publicado en 2011

Elevated plasma fractalkine levels are associated with higher levels of IL-6, Apo-B, LDL-C and insulin, but not with body composition in a large female twin sample

artículo científico publicado en 2013

Emotional intelligence and its association with orgasmic frequency in women

artículo científico publicado en 2009

Endogenous sex steroid levels in women with generalised osteoarthritis

artículo científico publicado el 1 de septiembre de 1991

Ensemble landmarking of 3D facial surface scans

artículo científico publicado en 2018

Epidemiology and genetic epidemiology of the liver function test proteins

artículo científico publicado en 2009

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies

artículo científico publicado en 2017

Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues

artículo científico publicado en 2016

Epigenetic associations of type 2 diabetes and BMI in an Arab population

artículo científico publicado en 2016

Epigenetic differences arise during the lifetime of monozygotic twins

artículo científico publicado en 2005

Epigenetic discrimination of identical twins from blood under the forensic scenario

artículo científico

Epigenetic findings in periodontitis in UK twins: a cross-sectional study

artículo científico publicado en 2019

Epigenetics and methylation in the rheumatic diseases

artículo científico

Epigenetics of discordant monozygotic twins: implications for disease

artículo científico publicado en 2014

Epigenome-Wide Association Study of Thyroid Function Traits Identifies Novel Associations of fT3 With <i>KLF9</i> and <i>DOT1L</i>

artículo científico publicado en 2021

Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density

artículo científico publicado en 2017

Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem

artículo científico publicado en 2014

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

artículo científico publicado en 2015

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

artículo científico publicado en 2016

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population

artículo científico publicado en 2012

Erratum to: Influence of acquired obesity on coronary vessel wall late gadolinium enhancement in discordant monozygote twins.

artículo científico publicado en 2017

Erratum to: signatures of early frailty in the gut microbiota

artículo científico publicado en 2016

Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

artículo científico publicado en 2015

Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants

artículo científico publicado en 2015

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

article

Erratum: Corrigendum: Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

scholarly article published in Nature Genetics

Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

artículo científico publicado en 2016

Erratum: Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Erratum: Whole-genome sequence-based analysis of thyroid function

artículo científico publicado en 2015

Estimates of the rate of infection and asymptomatic COVID-19 disease in a population sample from SE England

artículo científico publicado en 2020

Estimating heritability and shared environmental effects for refractive error in twin and family studies

artículo científico publicado en 2008

Estimating telomere length from whole genome sequence data

artículo científico publicado en 2014

Estrogen and COVID-19 symptoms: associations in women from the COVID Symptom Study

scholarly article by Ricardo Costeira published in 2020

Ethnic differences in F cell levels in Jamaica: a potential tool for identifying new genetic loci controlling fetal haemoglobin

artículo científico publicado en 2008

Evaluating the consent preferences of UK research volunteers for genetic and clinical studies

artículo científico publicado en 2015

Evaluation of HapMap data in six populations of European descent

artículo científico publicado en 2008

Evaluation of PAX3 genetic variants and nevus number.

artículo científico publicado en 2013

Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data

artículo científico publicado en 2012

Evidence for increased bone resorption in patients with progressive knee osteoarthritis: longitudinal results from the Chingford study

artículo científico publicado en 2002

Evidence for independent heritability of the glycation gap (glycosylation gap) fraction of HbA1c in nondiabetic twins

artículo científico publicado en 2006

Evidence for similarity in testosterone levels in haplotype identical brothers

scientific article published on 01 June 1988

Evidence of altered bone turnover, vitamin D and calcium regulation with knee osteoarthritis in female twins

artículo científico publicado en 2003

Evidence of association and linkage disequilibrium between a novel polymorphism in the transforming growth factor beta 1 gene and hip bone mineral density: a study of female twins

scientific article published on 01 January 2001

Evidence that bone mineral density plays a role in degenerative disc disease: the UK Twin Spine study

artículo científico publicado en 2010

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

artículo científico publicado en 2018

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

artículo científico publicado en 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Exploring genetic and environmental influences on miscarriage rates: a twin study.

artículo científico publicado en 2010

Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model

artículo científico publicado en 2016

Exploring the relationship between social jetlag with gut microbial composition, diet and cardiometabolic health, in the ZOE PREDICT 1 cohort

artículo científico publicado en 2023

Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity

artículo científico publicado en 2014

Extended haplotypes and linkage disequilibrium in the IL1R1-IL1A-IL1B-IL1RN gene cluster: association with knee osteoarthritis.

artículo científico publicado en 2004

Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4

Extension of the Segatella copri complex to 13 species with distinct large extrachromosomal elements and associations with host conditions

artículo científico publicado en 2023

Extensive weight loss can reduce immune age by altering IgG N-glycosylation

artículo científico publicado en 2020

Extent, causes, and consequences of small RNA expression variation in human adipose tissue

artículo científico publicado en 2012

FTO genotype is associated with phenotypic variability of body mass index

artículo científico publicado en 2012

Factors affecting pupil size after dilatation: the Twin Eye Study

artículo científico publicado en 2000

Faecal transplants

artículo científico publicado en 2015

Family history of appendicular fracture and risk of osteoporosis: a population-based study

scientific article published on 01 January 1999

Fear of falling limiting activity in young-old women is associated with reduced functional mobility rather than psychological factors

artículo científico publicado en 2005

Femoral neck trabecular patterns predict osteoporotic fractures

artículo científico publicado en 2002

Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome

scientific article published on 26 June 2019

First all-in-one diagnostic tool for DNA intelligence: genome-wide inference of biogeographic ancestry, appearance, relatedness, and sex with the Identitas v1 Forensic Chip

artículo científico publicado en 2012

Food Preference Patterns in a UK Twin Cohort

artículo científico publicado en 2015

Food neophobia shows heritable variation in humans

artículo científico publicado en 2007

Food: a new form of personalised (gut microbiome) medicine for chronic diseases?

artículo científico publicado en 2016

Fractures are not in genes – Authors' reply

artículo científico publicado en 2008

Free and serum testosterone levels in 276 males: a comparative study of rheumatoid arthritis, ankylosing spondylitis and healthy controls

artículo científico publicado en 1989

Frequency of osteoarthritis in hysterectomized women

artículo científico publicado el 1 de diciembre de 1991

Functional characterization of calcium sensing receptor polymorphisms and absence of association with indices of calcium homeostasis and bone mineral density

artículo científico publicado en 2006

Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis

artículo científico publicado en 2009

GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women

artículo científico publicado en 2011

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium

artículo científico publicado en 2016

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia

artículo científico publicado en 2018

Gender Differences in the Genetic Factors Responsible for Variation in Bone Density and Ultrasound

scientific article published on 01 April 2002

Gender and telomere length: systematic review and meta-analysis

artículo científico publicado en 2013

Gene expression changes with age in skin, adipose tissue, blood and brain

artículo científico publicado en 2013

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins

artículo científico publicado en 2014

Generalised Anxiety Disorder--A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression

artículo científico publicado en 2015

Generalized osteoarthritis in women: pattern of joint involvement and approaches to definition for epidemiological studies.

artículo científico publicado en 1996

Genes Control the Cessation of a Woman’s Reproductive Life: A Twin Study of Hysterectomy and Age at Menopause1

artículo científico publicado el 1 de junio de 1998

Genes and environment in refractive error: the twin eye study

scientific article published on 01 May 2001

Genes contributing to pain sensitivity in the normal population: an exome sequencing study.

artículo científico publicado en 2012

Genes versus environment. The relationship between dietary fat and total and central abdominal fat

artículo científico publicado en 1998

Genetic Determinants of the Gut Microbiome in UK Twins

artículo científico publicado en 2016

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

artículo científico publicado en 2016

Genetic Influences on Circulating Vitamin D Level: A Review

article

Genetic Influences on Female Infidelity and Number of Sexual Partners in Humans: A Linkage and Association Study of the Role of the Vasopressin Receptor Gene ( AVPR1A )

article

Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms

artículo científico publicado en 2016

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

scientific article published on 11 September 2020

Genetic Variation in Bone Mineral Density and Calcaneal Ultrasound: A Study of the Influence of Menopause Using Female Twins

artículo científico publicado en 2001

Genetic aetiology of blood pressure relates to aortic stiffness with bi-directional causality: evidence from heritability, blood pressure polymorphisms, and Mendelian randomization

artículo científico publicado en 2020

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and Dietary Factors Influencing the Progression of Nuclear Cataract

artículo científico publicado en 2016

Genetic and Environmental Contributions to Perceived Intensity and Pleasantness of Androstenone Odor: An International Twin Study

article by Antti J Knaapila et al published 3 January 2008 in Chemosensory perception

Genetic and environmental contributions to humor styles: a replication study

artículo científico publicado en 2008

Genetic and environmental determinants on bone loss in postmenopausal Caucasian women: a 14-year longitudinal twin study

artículo científico publicado en 2008

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODA

artículo científico publicado en 2016

Genetic and environmental factors in age-related nuclear cataracts in monozygotic and dizygotic twins

artículo científico publicado en 2000

Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.

scientific article published on 14 December 2016

Genetic and environmental influences on female sexual orientation, childhood gender typicality and adult gender identity.

artículo científico publicado en 2011

Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts

artículo científico publicado en 2016

Genetic and environmental influences on lipids, lipoproteins, and apolipoproteins: effects of menopause

artículo científico publicado en 2002

Genetic and environmental influences on psychological distress in the population: General Health Questionnaire analyses in UK twins

artículo científico publicado en 2003

Genetic and environmental influences on self-reported G-spots in women: a twin study.

artículo científico publicado en 2009

Genetic and environmental influences on stability and change in baseline levels of C-reactive protein: A longitudinal twin study.

artículo científico publicado en 2017

Genetic and environmental influences on total-body and central abdominal fat: the effect of physical activity in female twins

artículo científico publicado en 1999

Genetic and environmental risk factors for sexual distress and its association with female sexual dysfunction.

artículo científico publicado en 2011

Genetic and microbiome influence on lipid metabolism and dyslipidemia.

artículo científico publicado en 2017

Genetic architecture of circulating lipid levels

artículo científico publicado en 2011

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic associations between frozen shoulder and tennis elbow: a female twin study

artículo científico publicado en 2003

Genetic contribution to bone metabolism, calcium excretion, and vitamin D and parathyroid hormone regulation.

artículo científico publicado en 2001

Genetic contribution to renal function and electrolyte balance: a twin study

artículo científico publicado en 2002

Genetic control of the circulating concentration of transforming growth factor type beta1

scientific article published on 01 January 1999

Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood

artículo científico publicado en 2017

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

artículo científico publicado en 2014

Genetic determinism in the relationship between human CD4 + and CD8 + T lymphocyte populations?

article

Genetic effects on baseline values of C-reactive protein and serum amyloid a protein: a comparison of monozygotic and dizygotic twins

artículo científico publicado en 2003

Genetic epidemiology of hip and knee osteoarthritis

artículo científico publicado en 2010

Genetic evidence of assortative mating in humans

scholarly article

Genetic factors and osteoporotic fractures in elderly people. Twin data support genetic contribution to risk of fracture

artículo científico publicado en 2000

Genetic influence on bone turnover in postmenopausal twins

scientific article published on 01 January 1996

Genetic influence on early age-related maculopathy: a twin study

artículo científico publicado en 2002

Genetic influence on peripheral blood T lymphocyte levels

artículo científico publicado en 2000

Genetic influence on the progression of radiographic knee osteoarthritis: a longitudinal twin study

artículo científico publicado en 2006

Genetic influences in gastro-oesophageal reflux disease: a twin study

artículo científico publicado en 2003

Genetic influences in gastro-oesophageal reflux disease: a twin study

article by I Mohammed et al published 1 October 2003 in Journal of Medical Genetics

Genetic influences in irritable bowel syndrome: a twin study

artículo científico publicado en 2005

Genetic influences in self-reported symptoms of obstructive sleep apnoea and restless legs: a twin study

artículo científico publicado en 2004

Genetic influences on F cells and other hematologic variables: a twin heritability study

scientific article published on 01 January 2000

Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins

artículo científico publicado en 1999

Genetic influences on cognitive function using The Cambridge Neuropsychological Test Automated Battery

Genetic influences on exercise participation in 37,051 twin pairs from seven countries

artículo científico publicado en 2006

Genetic influences on motion sickness susceptibility in adult women: a classical twin study

artículo científico publicado en 2006

Genetic influences on osteoarthritis in women: a twin study

artículo científico publicado en 1996

Genetic influences on variation in female orgasmic function: a twin study

artículo científico publicado en 2005

Genetic insights into biological mechanisms governing human ovarian ageing

artículo científico publicado en 2021

Genetic interactions affecting human gene expression identified by variance association mapping

artículo científico publicado en 2014

Genetic loci influencing kidney function and chronic kidney disease

artículo científico publicado en 2010

Genetic loci linked to pituitary-thyroid axis set points: a genome-wide scan of a large twin cohort

artículo científico publicado en 2008

Genetic polymorphisms of innate immunity-related inflammatory pathways and their association with factors related to type 2 diabetes.

artículo científico publicado en 2011

Genetic predictors of fibrin D-dimer levels in healthy adults

artículo científico publicado en 2011

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

artículo científico publicado en 2016

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variation at 16q24.2 is associated with small vessel stroke

artículo científico publicado en 2016

Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis

artículo científico publicado en 2010

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genetics of fibrin clot structure: a twin study.

artículo científico publicado en 2003

Genetics of osteoporosis from genome-wide association studies: advances and challenges

artículo científico publicado el 18 de julio de 2012

Genetics of risk factors for melanoma: an adult twin study of nevi and freckles.

artículo científico publicado en 2000

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up

artículo científico publicado en 2015

Genetics of the human face: Identification of large-effect single gene variants

artículo científico publicado en 2018

Genetics, the Big Five, and the tendency to be self-employed

scientific article published on 01 November 2010

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans

artículo científico publicado en 2013

Genome-Wide Association Shows that Pigmentation Genes Play a Role in Skin Aging

artículo científico publicado en 2017

Genome-Wide Association Studies Identify Multiple Genetic Loci Influencing Eyebrow Color Variation in Europeans

artículo científico publicado en 2019

Genome-Wide Association Study Identifies Two Novel Loci Associated with Female Stress and Urgency Urinary Incontinence

artículo científico publicado en 2021

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

artículo científico publicado en 2016

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

scientific article published on 27 February 2020

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

artículo científico publicado en 2018

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

artículo científico publicado en 2016

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

artículo científico publicado en 2014

Genome-wide association analyses based on whole-genome sequencing in Sardinia provide insights into regulation of hemoglobin levels

artículo científico publicado en 2015

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

artículo científico publicado en 2013

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

artículo científico publicado en 2013

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

artículo científico publicado en 2022

Genome-wide association analysis identifies multiple loci related to resting heart rate

artículo científico publicado en 2010

Genome-wide association analysis identifies six new loci associated with forced vital capacity

artículo científico publicado en 2014

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

artículo científico publicado en 2011

Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits

scientific journal article

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis

artículo científico publicado en 2014

Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand

artículo científico

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

scientific journal article

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

artículo científico publicado en 2011

Genome-wide association identifies ATOH7 as a major gene determining human optic disc size

artículo científico publicado en 2010

Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology

artículo científico publicado en 2010

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

artículo científico publicado en 2018

Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis

scientific journal article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

artículo científico publicado en 2012

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

artículo científico publicado en 2014

Genome-wide association study identifies 48 common genetic variants associated with handedness

artículo científico publicado en 2020

Genome-wide association study identifies 74 loci associated with educational attainment

artículo científico publicado en 2016

Genome-wide association study identifies eight loci associated with blood pressure

artículo científico publicado en 2009

Genome-wide association study identifies five loci associated with lung function

artículo científico publicado en 2010

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

artículo científico publicado en 2008

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

artículo científico publicado en 2011

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

artículo científico publicado en 2018

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

artículo científico publicado en 2015

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.

artículo científico publicado en 2014

Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

artículo científico publicado en 2010

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi

artículo científico publicado en 2009

Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort

artículo científico publicado en 2014

Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.

artículo científico publicado en 2018

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

artículo científico publicado en 2018

Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02

artículo científico publicado en 2019

Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation

artículo científico publicado en 2017

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

artículo científico publicado en 2013

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

artículo científico publicado en 2010

Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior

artículo científico publicado en 2016

Genome-wide association study of hoarding traits

artículo científico publicado en 2010

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

artículo científico publicado en 2016

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

article

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

artículo científico publicado en 2018

Genome-wide association study of smoking initiation and current smoking

artículo científico publicado en 2009

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk

artículo científico publicado en 2011

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density

artículo científico publicado en 2016

Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes

artículo científico publicado en 2015

Genome-wide average DNA methylation is determined in utero

artículo científico publicado en 2018

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

artículo científico publicado en 2012

Genome-wide linkage scan for athlete status in 700 British female DZ twin pairs

artículo científico publicado en 2007

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

artículo científico publicado en 2013

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

artículo científico publicado en 2012

Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne

artículo científico publicado en 2018

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide meta-analysis of common variant differences between men and women

artículo científico publicado en 2012

Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

artículo científico publicado en 2012

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus

artículo científico publicado en 2018

Genome-wide methylation analysis of a large population sample shows neurological pathways involvement in chronic widespread musculoskeletal pain

artículo científico publicado en 2017

Genome-wide scan for blood pressure suggests linkage to chromosome 11, and replication of loci on 16, 17, and 22.

artículo científico publicado en 2004

Genome-wide scan for prospective memory suggests linkage to chromosome 12q22.

artículo científico publicado en 2005

Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

artículo científico publicado en 2020

Genome-wide search for nevus density shows linkage to two melanoma loci on chromosome 9 and identifies a new QTL on 5q31 in an adult twin cohort

article by Mario Falchi et al published 23 August 2006 in Human Molecular Genetics

Genomewide linkage scan of hand osteoarthritis in female twin pairs showing replication of quantitative trait loci on chromosomes 2 and 19

artículo científico publicado en 2006

Genomic Insights into Adaptations of Trimethylamine-Utilizing Methanogens to Diverse Habitats, Including the Human Gut

scientific article published in 2021

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

artículo científico publicado en 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

artículo científico publicado en 2017

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

artículo científico publicado en 2021

Genomics and metabolomics of muscular mass in a community-based sample of UK females

artículo científico publicado en 2015

Geo-social gradients in predicted COVID-19 prevalence and severity in Great Britain: results from 2,266,235 users of the COVID-19 Symptoms Tracker app

artículo científico publicado en 2020

Geo-social gradients in predicted COVID-19 prevalence in Great Britain: results from 1 960 242 users of the COVID-19 Symptoms Study app

artículo científico publicado en 2020

Geographical structure and differential natural selection among North European populations

scientific article published on 05 March 2009

Geometric measurements of the proximal femur in UK women: Secular increase between the late 1950s and early 1990s

artículo científico publicado en 1996

Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux

artículo científico publicado en 2013

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements.

artículo científico publicado en 2013

Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements

artículo científico publicado en 2013

Global genetic architecture of an erythroid quantitative trait locus, HMIP-2

artículo científico publicado en 2014

Global variability of the human IgG glycome

artículo científico publicado en 2020

Glycaemic variability, assessed with continuous glucose monitors, is associated with diet, lifestyle and health in people without diabetes.

Glycans are a novel biomarker of chronological and biological ages

artículo científico publicado en 2013

Glycosylation Profile of IgG in Moderate Kidney Dysfunction

artículo científico publicado en 2015

Glycosylation Profile of Immunoglobulin G Is Cross-Sectionally Associated With Cardiovascular Disease Risk Score and Subclinical Atherosclerosis in Two Independent Cohorts.

artículo científico publicado en 2018

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases

artículo científico publicado en 2020

Glycosylation of immunoglobulin g: role of genetic and epigenetic influences

artículo científico publicado en 2013

Gradient Boosting as a SNP Filter: an Evaluation Using Simulated and Hair Morphology Data.

artículo científico publicado en 2013

Gut microbial diversity is associated with lower arterial stiffness in women.

artículo científico publicado en 2018

Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain

artículo científico publicado en 2017

Gut microbiota associations with common diseases and prescription medications in a population-based cohort

artículo científico publicado en 2018

Gut-Microbiota-Metabolite Axis in Early Renal Function Decline

artículo científico publicado en 2015

HLA Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut Microbiome

artículo científico publicado en 2019

HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome: Supplementary Information

scholarly article published 11 January 2019

Habitual flavonoid intakes are positively associated with bone mineral density in women

artículo científico publicado en 2012

Haplotypes of the low-density lipoprotein receptor-related protein 5 (LRP5) gene: Are they a risk factor in osteoarthritis?

article

Happy families: a twin study of humour

artículo científico publicado en 2000

HbA(1c) levels are genetically determined even in type 1 diabetes: evidence from healthy and diabetic twins

artículo científico publicado en 2001

HbA2levels in normal adults are influenced by two distinct genetic mechanisms

artículo científico publicado en 2012

Health-related quality of life in osteoporosis clinical trials. The Osteoporosis Quality of Life Study Group

artículo científico publicado en 1993

Hearing ability with age in northern European women: a new web-based approach to genetic studies

artículo científico publicado en 2012

Height and bone mineral density are associated with naevus count supporting the importance of growth in melanoma susceptibility

artículo científico publicado en 2015

Hemodynamic Mechanism of the Age-Related Increase in Pulse Pressure in Women

artículo científico publicado en 2019

Hereditary factors in basal cell carcinoma of the skin: a population-based cohort study in twins

artículo científico publicado en 2000

Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: evidence from UK twins

artículo científico publicado en 2013

Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping

artículo científico publicado en 2017

Heritability of DNA-damage-induced apoptosis and its relationship with age in lymphocytes from female twins

artículo científico publicado en 2006

Heritability of QT interval: how much is explained by genes for resting heart rate?

artículo científico publicado en 2007

Heritability of Raynaud's phenomenon and vascular responsiveness to cold: A study of adult female twins

artículo científico publicado en 2007

Heritability of adult body height: a comparative study of twin cohorts in eight countries

artículo científico publicado en 2003

Heritability of central systolic pressure augmentation: a twin study

artículo científico publicado en 2000

Heritability of clot formation, morphology, and lysis: the EuroCLOT study

artículo científico publicado en 2007

Heritability of insulin sensitivity and lipid profile depend on BMI: evidence for gene-obesity interaction

artículo científico publicado en 2009

Heritability of intraocular pressure: a classical twin study

artículo científico publicado en 2008

Heritability of macular pigment: a twin study

artículo científico publicado en 2005

Heritability of objectively assessed daily physical activity and sedentary behavior

artículo científico publicado en 2013

Heritability of responses to painful stimuli in women: a classical twin study

artículo científico publicado en 2007

Heritability of serum TSH, free T4 and free T3 concentrations: a study of a large UK twin cohort

artículo científico publicado en 2007

Heritability of strabismus: genetic influence is specific to eso-deviation and independent of refractive error

artículo científico publicado en 2012

Heritability of the second to fourth digit ratio (2d:4d): A twin study

artículo científico publicado en 2006

Heritable components of the human fecal microbiome are associated with visceral fat.

artículo científico publicado en 2016

Heritable components of the human fecal microbiome are associated with visceral fat.

artículo científico publicado en 2017

High intake of vegetables is linked to lower white blood cell profile and the effect is mediated by the gut microbiome

Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma

artículo científico publicado en 2016

Higher anthocyanin intake is associated with lower arterial stiffness and central blood pressure in women

artículo científico publicado en 2012

Higher dietary flavonoid intakes are associated with lower objectively measured body composition in women: evidence from discordant monozygotic twins

scientific article published on 18 January 2017

Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women

artículo científico publicado en 2007

Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome

artículo científico publicado en 2017

Homocysteine levels and leukocyte telomere length.

artículo científico publicado en 2008

Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women.

artículo científico publicado en 2010

Host genetic variation impacts microbiome composition across human body sites

artículo científico publicado en 2015

How people wake up is associated with previous night's sleep together with physical activity and food intake

artículo científico publicado en 2022

How serious is knee osteoarthritis?

artículo científico publicado el 1 de octubre de 1992

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

artículo científico publicado en 2010

Human genetics shape the gut microbiome.

artículo científico publicado en 2014

Human metabolic individuality in biomedical and pharmaceutical research

artículo científico publicado en 2011

Human metabolic profiles are stably controlled by genetic and environmental variation

artículo científico publicado en 2011

Human postprandial responses to food and potential for precision nutrition

artículo científico publicado en 2020

Human serum metabolic profiles are age dependent

artículo científico publicado en 2012

Human telomere biology: pitfalls of moving from the laboratory to epidemiology

artículo científico publicado en 2006

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Hypermethylation in the ZBTB20 gene is associated with major depressive disorder

artículo científico publicado en 2014

IRF4 variants have age-specific effects on nevus count and predispose to melanoma

artículo científico publicado en 2010

Identical twins carry a persistent epigenetic signature of early genome programming

artículo científico publicado en 2021

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Identification and replication of three novel myopia common susceptibility gene loci on chromosome 3q26 using linkage and linkage disequilibrium mapping

artículo científico publicado en 2008

Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility

artículo científico publicado en 2016

Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study

artículo científico publicado en 2008

Identification of QTLs for serum lipid levels in a female sib-pair cohort: a novel application to improve the power of two-locus linkage analysis

article

Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis

artículo científico publicado en 2008

Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

artículo científico publicado en 2011

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

artículo científico publicado el 3 de julio de 2012

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

artículo científico publicado en 2014

Identification of novel loci associated with hip shape: a meta-analysis of genome-wide association studies

Identification of optimal symptom combinations to trigger diagnostic work-up of suspected COVID-19 cases: analysis from a community-based, prospective, observational cohort

scientific article published on 01 December 2020

Identification of quantitative trait loci for fibrin clot phenotypes: the EuroCLOT study

artículo científico publicado en 2009

Identification of seven loci affecting mean telomere length and their association with disease

artículo científico publicado en 2013

IgA1 Glycosylation Is Heritable in Healthy Twins

artículo científico publicado en 2016

IgG glycosylation and DNA methylation are interconnected with smoking

artículo científico publicado en 2017

Illness duration and symptom profile in a large cohort of symptomatic UK school-aged children tested for SARS-CoV-2

artículo científico publicado en 2021

Imaging of pelvic fracture in a patient with psoriatic arthritis

artículo científico publicado en 1999

Immune Trait Shifts in Association With Tobacco Smoking: A Study in Healthy Women

scientific article published in 2021

Immunoglobulin G glycosylation and clinical outcome in rheumatoid arthritis during pregnancy.

artículo científico

Impact of COVID-19 on health behaviours and body weight: A prospective observational study in a cohort of 1.1 million UK and US individuals

artículo científico publicado en 2021

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Implementation of the simplified stochastic model of ageing for longitudinal osteoarthritis data assessment

artículo científico publicado en 2012

Improved Cardiometabolic Health Using a Personalised Nutrition Approach: The ZOE METHOD Study

Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation

artículo científico publicado en 2013

Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity

artículo científico publicado en 1994

Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study

artículo científico publicado en 1999

Increased levels of urinary collagen crosslinks in females with rheumatoid arthritis

artículo científico publicado en 1993

Increased rates of previous hysterectomy and gynaecological operations in women with osteoarthritis

artículo científico publicado en 1988

Increased wave reflection rather than central arterial stiffness is the main determinant of raised pulse pressure in women and relates to mismatch in arterial dimensions: a twin study

artículo científico publicado en 2009

Independent genetic factors determine the amount and distribution of fat in women after the menopause

artículo científico publicado en 1997

Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis

artículo científico publicado en 2014

Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS.

artículo científico publicado en 2017

Inference of the genetic architecture underlying BMI and height with the use of 20,240 sibling pairs

artículo científico publicado en 2013

Inflammation-induced cartilage degradation in female rodents. Protective role of sex hormones

artículo científico publicado en 1993

Influence of Current and Past Hormone Replacement Therapy on Bone Mineral Density: A Study of Discordant Postmenopausal Twins

scientific article published on 01 January 1999

Influence of acquired obesity on coronary vessel wall late gadolinium enhancement in discordant monozygote twins.

artículo científico publicado en 2016

Influence of oral contraception on the occurrence of rheumatoid arthritis in female sibs

artículo científico publicado en 1990

Influence of vitamin D receptor genotype on bone mineral density in postmenopausal women: a twin study in Britain

artículo científico publicado en 1995

Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes

artículo científico publicado en 2011

Innate and adaptive immune traits are differentially affected by genetic and environmental factors

artículo científico publicado en 2017

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

artículo científico publicado en 2010

Insights into the genetics of osteoporosis from recent genome-wide association studies

artículo científico publicado el 26 de agosto de 2011

Intakes of anthocyanins and flavones are associated with biomarkers of insulin resistance and inflammation in women

artículo científico publicado en 2013

Integrated multiomics approach identifies calcium and integrin-binding protein-2 as a novel gene for pulse wave velocity

artículo científico publicado en 2015

Integrating Metagenomic Information into Personalized Nutrition Tools: The PREDICT I Study (P20-005-19)

Integration of 'omics' data in aging research: from biomarkers to systems biology

artículo científico publicado en 2015

Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs

artículo científico publicado en 2016

Interaction between allelic variations in vitamin D receptor and retinoid X receptor genes on metabolic traits

artículo científico publicado en 2014

Interaction between two quantitative trait loci affects fetal haemoglobin expression

artículo científico publicado en 2005

Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults

artículo científico publicado en 2007

Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study

artículo científico publicado en 2009

Interplay between the human gut microbiome and host metabolism

scientific article published on 03 October 2019

Interpreting the results of a segregation analysis of generalized radiographic osteoarthritis: comment on the article by Felson et al

artículo científico publicado en 1999

Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids

artículo científico publicado en 2014

Intervertebral T-Score Differences in Younger and Older Women

artículo científico publicado el 19 de junio de 2012

Intrauterine, environmental, and genetic influences in the relationship between birth weight and lipids in a female twin cohort

artículo científico publicado en 2006

Intrinsic and extrinsic risk factors for sagging eyelids

artículo científico publicado en 2014

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

artículo científico publicado en 2016

Investigating the Epigenetic Discrimination of Identical Twins Using Buccal Swabs, Saliva, and Cigarette Butts in the Forensic Setting.

artículo científico publicado en 2018

Investigation of linkage on chromosome 2q and hand and knee osteoarthritis

artículo científico publicado en 2002

Is hormone replacement therapy protective for hand and knee osteoarthritis in women?: The Chingford study

artículo científico publicado el 1 de julio de 1997

Is low birth weight an antecedent of CKD in later life? A systematic review of observational studies

artículo científico publicado en 2009

Is poor pregnancy outcome a risk factor in rheumatoid arthritis?

artículo científico publicado en 1990

Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity?

artículo científico publicado en 2007

Ischemic stroke is associated with the ABO locus: the EuroCLOT study

artículo científico publicado en 2013

Joint Linkage and Association of Six Single-Nucleotide Polymorphisms in the Factor XIII-A Subunit Gene Point to V34L As the Main Functional Locus

article

KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern

artículo científico publicado en 2019

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

artículo científico publicado en 2016

Kellgren & Lawrence grade 1 osteophytes in the knee--doubtful or definite?

scientific article published on 01 February 2003

Keratan sulphate in rheumatoid arthritis, osteoarthritis, and inflammatory diseases

artículo científico publicado el 1 de octubre de 1992

Ketogenic diet and ketone bodies enhance the anticancer effects of PD1 blockade

artículo científico publicado en 2020

Key predictors of attending hospital with COVID19: An association study from the COVID Symptom Tracker App in 2,618,948 individuals

artículo científico publicado en 2020

Kicking Back Cognitive Ageing: Leg Power Predicts Cognitive Ageing after Ten Years in Older Female Twins

artículo científico publicado en 2015

Kin recognition signals in adult faces.

artículo científico publicado en 2008

Klotho gene polymorphisms associated with bone density of aged postmenopausal women

scientific article published on 01 October 2002

Knowledge barriers in the symptomatic-COVID-19 testing programme in the UK: an observational study

artículo científico publicado en 2021

Lack of association between leukocyte telomere length and genetic variants in two ageing-related candidate genes

artículo científico publicado en 2007

Lack of heritability of circulating leptin concentration in humans after adjustment for body size and adiposity using a physiological approach

scientific article published on 01 November 2001

Large Inter-individual Variation in Postprandial Lipemia Following a Mixed Meal in over 1000 Twins and Singletons from the UK and US: The PREDICT I Study (OR19-06-19)

artículo científico publicado en 2019

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

artículo científico publicado en 2012

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis

article

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations

artículo científico publicado en 2011

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

artículo científico publicado en 2015

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

artículo científico publicado en 2017

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

artículo científico publicado en 2009

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditions

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

artículo científico publicado en 2018

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

artículo científico publicado en 2015

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis

artículo científico publicado en 2010

Leukocyte telomere length is associated with cognitive performance in healthy women

artículo científico publicado en 2008

Level of an advanced glycated end product is genetically determined: a study of normal twins

artículo científico publicado en 2003

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

artículo científico publicado en 2018

Linkage and Association for Bone Mineral Density and Heel Ultrasound Measurements with a Simple Tandem Repeat Polymorphism near the Osteocalcin Gene in Female Dizygotic Twins

article

Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort

artículo científico publicado en 2006

Linkage of genes to total lean body mass in normal women

artículo científico publicado en 2007

Linkage to the FOXC2 region of chromosome 16 for varicose veins in otherwise healthy, unselected sibling pairs

artículo científico publicado en 2005

Lipidomics profiling and risk of cardiovascular disease in the prospective population-based Bruneck study

artículo científico publicado en 2014

Loci at chromosomes 13, 19 and 20 influence age at natural menopause

artículo científico publicado en 2009

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

artículo científico publicado en 2009

Long term conservation of human metabolic phenotypes and link to heritability

artículo científico publicado en 2014

Longitudinal evaluation of sexual function in a cohort of pre- and postmenopausal women

artículo científico publicado en 2015

Longitudinal study of variation in body mass index in middle-aged UK females

artículo científico publicado en 2011

Loss of smell and taste in combination with other symptoms is a strong predictor of COVID-19 infection

artículo científico publicado en 2020

Low back and common widespread pain share common genetic determinants

artículo científico publicado en 2014

Low copy number of the salivary amylase gene predisposes to obesity.

artículo científico publicado en 2014

Low free testosterone levels in rheumatoid arthritis

artículo científico publicado en 1988

Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease

scientific article published on 01 April 1997

Lower limbs composition and radiographic knee osteoarthritis (RKOA) in Chingford sample--a longitudinal study

artículo científico publicado en 2012

Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study

artículo científico publicado en 2011

Lumbar disc disease shows linkage to chromosome 19 overlapping with a QTL for hand OA.

artículo científico publicado en 2007

Machine learning integration of multimodal data identifies key features of blood pressure regulation

artículo científico publicado en 2022

Male-pattern baldness susceptibility locus at 20p11.

artículo científico publicado en 2008

Managing clinically significant findings in research: the UK10K example

artículo científico publicado en 2014

Mapping cis- and trans-regulatory effects across multiple tissues in twins

artículo científico publicado en 2012

Mapping genetic loci that determine leukocyte telomere length in a large sample of unselected female sibling pairs

artículo científico publicado en 2006

Markers of bone metabolism in postmenopausal women with rheumatoid arthritis. Effects of corticosteroids and hormone replacement therapy

scientific article published on 01 July 1995

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

artículo científico publicado en 2019

Meal-induced inflammation: postprandial insights from the Personalised REsponses to DIetary Composition Trial (PREDICT) study in 1000 participants

Measurement of structural progression in osteoarthritis of the hip: the Barcelona consensus group.

artículo científico publicado en 2004

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

artículo científico publicado en 2013

Menopause is associated with postprandial metabolism, metabolic health and lifestyle: The ZOE PREDICT study

artículo científico publicado en 2022

Menopause modifies the association of leukocyte telomere length with insulin resistance and inflammation

artículo científico publicado en 2005

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

artículo científico publicado en 2012

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance

artículo científico publicado en 2014

Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness

artículo científico publicado en 2017

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

artículo científico publicado en 2009

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

artículo científico publicado en 2016

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

artículo científico publicado en 2015

Meta-analysis of epigenome-wide association studies of cognitive abilities

artículo científico publicado en 2018

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

artículo científico publicado en 2009

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

artículo científico publicado en 2010

Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair

artículo científico publicado en 2017

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

artículo científico publicado en 2014

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

artículo científico publicado en 2013

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

artículo científico publicado en 2012

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

artículo científico publicado en 2011

Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size

artículo científico publicado en 2009

Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass

artículo científico publicado en 2007

Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm

artículo científico publicado en 2013

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women

artículo científico publicado en 2013

Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.

artículo científico publicado en 2018

Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect

artículo científico publicado en 2013

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

Metabolites of milk intake: a metabolomic approach in UK twins with findings replicated in two European cohorts.

artículo científico publicado en 2016

Metabolomic Pathways to Osteoporosis in Middle-Aged Women: A Genome-Metabolome-Wide Mendelian Randomization Study

artículo científico publicado en 2017

Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain.

artículo científico publicado en 2017

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate

artículo científico publicado en 2015

Metabolomic markers reveal novel pathways of ageing and early development in human populations

scientific article published on 08 July 2013

Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns

artículo científico publicado en 2019

Metabolomic profiling to dissect the role of visceral fat in cardiometabolic health

artículo científico publicado en 2016

Metabolomic signatures of low birthweight: Pathways to insulin resistance and oxidative stress

artículo científico publicado en 2018

Metabolomic study of carotid-femoral pulse-wave velocity in women

artículo científico publicado en 2015

Metabolomics profiling reveals novel markers for leukocyte telomere length.

artículo científico publicado en 2016

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

scientific article published on 12 August 2019

Meta‐Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

artículo científico publicado en 2019

Methodologic issues in clinical trials for prevention or risk reduction in osteoarthritis

artículo científico publicado en 2011

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals

Migraine and Antiphospholipid Antibodies: No Association Found in Migraine-Discordant Monozygotic Twins

artículo científico publicado en 2008

Mitochondrial DNA heteroplasmy in diabetes and normal adults: role of acquired and inherited mutational patterns in twins.

artículo científico publicado en 2012

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies

artículo científico publicado en 2017

Mixing omics: combining genetics and metabolomics to study rheumatic diseases

artículo científico publicado en 2017

Modeling with measured genotypes: effects of the vitamin D receptor gene, age, and latent genetic and environmental factors on bone mineral density

artículo científico publicado en 2004

Moderate Alcohol Consumption, Dietary Fat Composition, and Abdominal Obesity in Women: Evidence for Gene-Environment Interaction

artículo científico publicado el 1 de noviembre de 2003

Moderate alcohol consumption, estrogen replacement therapy, and physical activity are associated with increased insulin sensitivity: is abdominal adiposity the mediator?

artículo científico publicado en 2003

Modest effects of dietary supplements during the COVID-19 pandemic: insights from 445 850 users of the COVID-19 Symptom Study app

artículo científico publicado en 2021

Modulation of genetic associations with serum urate levels by body-mass-index in humans

artículo científico publicado en 2015

Molecular pathways associated with blood pressure and hexadecanedioate levels

artículo científico publicado en 2017

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

artículo científico publicado en 2015

Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci

artículo científico publicado en 2009

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

artículo científico publicado en 2013

Multimodality imaging of subclinical aortic atherosclerosis: relation of aortic stiffness to calcification and plaque in female twins.

artículo científico publicado en 2013

Multiple loci are associated with white blood cell phenotypes

artículo científico publicado en 2011

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

artículo científico publicado en 2009

Multisite Quantitative Ultrasound: Colles’ Fracture Discrimination in Postmenopausal Women

artículo científico publicado en 2002

Multisite quantitative ultrasound: precision, age- and menopause-related changes, fracture discrimination, and T-score equivalence with dual-energy X-ray absorptiometry.

artículo científico publicado en 2001

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

artículo científico publicado en 2017

Natural history and risk factors for bone loss in postmenopausal Caucasian women: a 15-year follow-up population-based study

artículo científico publicado en 2008

Natural history of naevi: a two-wave study

artículo científico publicado en 2020

Network-based metabolite ratios for an improved functional characterization of genome-wide association study results

Neuropathic features of joint pain: a community-based study

artículo científico publicado en 2013

Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo.

artículo científico publicado en 2007

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

scientific article published on 29 July 2019

New gene functions in megakaryopoiesis and platelet formation

artículo científico publicado en 2011

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

artículo científico publicado en 2016

No clear genetic influences on the association between dyslexia and anxiety in a population-based sample of female twins

artículo científico publicado en 2009

No correlation between childhood maltreatment and telomere length

artículo científico publicado en 2010

No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls

artículo científico publicado en 2012

Nonadditive Effects of Genes in Human Metabolomics

artículo científico publicado en 2015

Normal variations in personality are associated with coital orgasmic infrequency in heterosexual women: a population-based study

artículo científico publicado en 2008

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis

artículo científico publicado en 2016

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

artículo científico publicado en 2014

Novel association suggests multiple independent QTLs within chromosome 5q21-33 region control variation in total humans IgE levels

artículo científico publicado en 2003

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

artículo científico publicado en 2010

Novel genes for QTc interval. How much heritability is explained, and how much is left to find?

artículo científico publicado en 2010

Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses

artículo científico publicado en 2014

Novel genetic loci affecting facial shape variation in humans

artículo científico publicado en 2019

Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects

artículo científico publicado en 2012

Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study

artículo científico publicado en 2014

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia.

artículo científico publicado en 2007

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

artículo científico publicado en 2018

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Novel regional age-associated DNA methylation changes within human common disease-associated loci

artículo científico publicado en 2016

O57 Des variations du nombre de copies au niveau d’un CNV fréquent contribuent très fortement au risque d’obésité

artículo científico publicado en 2012

OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis.

artículo científico publicado en 2009

Obesity accelerates epigenetic aging of human liver

artículo científico publicado en 2014

Obesity is Associated with Genetic Variants That Alter Dopamine Availability

artículo científico publicado en 2006

Obesity is an important determinant of baseline serum C-reactive protein concentration in monozygotic twins, independent of genetic influences

artículo científico publicado en 2004

Obesity reveals an association between blood pressure and the G-protein beta3-subunit gene: a study of female dizygotic twins

artículo científico publicado en 2004

Obesity, cigarette smoking, and telomere length in women

artículo científico publicado en 2005

Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci

artículo científico publicado en 2018

Oestrogens, bones and systemic lupus erythematosus

artículo científico publicado en 1993

Offspring's leukocyte telomere length, paternal age, and telomere elongation in sperm

artículo científico publicado en 2008

Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women.

artículo científico publicado en 2017

Omics technologies and the study of human ageing

artículo científico publicado en 2013

Optimal symptom combinations to aid COVID-19 case identification: Analysis from a community-based, prospective, observational cohort

artículo científico publicado en 2021

Oral contraceptives and rheumatoid arthritis. Bias in observational studies of cause-effect relationships

scientific article published on 01 January 1987

Oral statins and increased bone-mineral density in postmenopausal women

artículo científico publicado en 2000

Osteoarthritis

Osteoarthritis: new insights. Part 1: the disease and its risk factors.

artículo científico publicado en 2000

Osteophytes, enthesophytes, and high bone mass: a bone-forming triad with potential relevance in osteoarthritis

artículo científico publicado en 2014

Osteoporosis in rheumatoid arthritis

scientific article published on 01 June 1995

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene.

artículo científico publicado en 2017

Pain reporting at different body sites is explained by a single underlying genetic factor

artículo científico publicado en 2010

Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women

artículo científico publicado en 2015

Parametric model-based statistics for possible genotyping errors and sample stratification in sibling-pair SNP data

artículo científico publicado en 2010

Parathyroid hormone(1-84) treatment of postmenopausal women with low bone mass receiving hormone replacement therapy

artículo científico publicado en 2008

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

artículo científico publicado en 2014

Parental mortality and rheumatoid arthritis

artículo científico publicado el 1 de enero de 1988

Paternal age and telomere length in twins: the germ stem cell selection paradigm

artículo científico publicado en 2015

Pathway based factor analysis of gene expression data produces highly heritable phenotypes that associate with age

article

Pathway-based factor analysis of gene expression data produces highly heritable phenotypes that associate with age.

artículo científico publicado en 2015

Patients who have had fractures of the distal forearm do not lose bone as expected

artículo científico publicado en 1996

Patterns of joint involvement in osteoarthritis of the hand: the Chingford Study

scientific article published on 01 August 1995

Personalised REsponses to DIetary Composition Trial (PREDICT): an intervention study to determine inter-individual differences in postprandial response to foods

Phenotypic and genetic relations between the HEXACO dimensions and trait emotional intelligence

artículo científico publicado en 2010

Phosphatidylinositol 3-kinase p85alpha regulatory subunit gene PIK3R1 haplotype is associated with body fat and serum leptin in a female twin population

artículo científico publicado en 2006

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

artículo científico publicado en 2011

Physical activity reduces genetic susceptibility to increased central systolic pressure augmentation: a study of female twins.

artículo científico publicado en 2003

Pigmentation and vitamin D metabolism in Caucasians: low vitamin D serum levels in fair skin types in the UK

artículo científico publicado en 2009

Plasma adiponectin concentrations are associated with body composition and plant-based dietary factors in female twins

artículo científico publicado en 2008

Plasma protein N-glycome composition associates with postprandial lipaemic response

Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes

artículo científico publicado en 2015

Polymorphisms in ALOX12, but not ALOX15, Are Significantly Associated With BMD in Postmenopausal Women

artículo científico publicado en 2007

Polymorphisms of the vitamin D receptor gene do not predict quantitative ultrasound of the calcaneus or hip axis length

artículo científico publicado en 1996

Polymorphisms of the vitamin D receptor, infant growth, and adult bone mass

artículo científico publicado en 1997

Population genetic differentiation of height and body mass index across Europe

artículo científico publicado en 2015

Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation

artículo científico publicado en 2015

Positive Association Between Vitamin D Serum Levels and Naevus Counts

artículo científico publicado en 2016

Post-vaccination SARS-CoV-2 infection: risk factors and illness profile in a prospective, observational community-based case-control study

artículo científico publicado en 2021

Postprandial glycaemic dips predict appetite and energy intake in healthy individuals

Predicting Incident Radiographic Knee Osteoarthritis in Middle-Aged Women Within Four Years: The Importance of Knee-Level Prognostic Factors

artículo científico publicado en 2020

Predicting Personal Metabolic Responses to Food Using Multi-omics Machine Learning in over 1000 Twins and Singletons from the UK and US: The PREDICT I Study (OR31-01-19)

scholarly article by Sarah Berry et al published 13 June 2019 in CURRENT DEVELOPMENTS IN NUTRITION

Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker

artículo científico publicado en 2017

Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues

artículo científico publicado en 2017

Predicting causal variants affecting expression using whole genome sequence and RNA-seq from multiple human tissues

scholarly article published 21 November 2016

Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements

artículo científico publicado en 2015

Predicting the Risk of Fracture at Any Site in the Skeleton: Are All Bone Mineral Density Measurement Sites Equally Effective?

artículo científico publicado en 2005

Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors

artículo científico publicado en 2013

Prediction of high naevus count in a healthy U.K. population to estimate melanoma risk.

artículo científico publicado en 2015

Pregnancy and Rheumatoid Arthritis: An Overview

artículo científico publicado el 1 de octubre de 1992

Prevalence of premature ovarian failure in monozygotic and dizygotic twins

artículo científico publicado en 2006

Prevalence of radiographic hip osteoarthritis is increased in high bone mass

artículo científico publicado en 2014

Prevalence of reported knee pain over twelve years in a community-based cohort.

artículo científico publicado en 2011

Prevalence of rheumatoid arthritis and rheumatoid factor in women: evidence for a secular decline

artículo científico publicado en 1993

Prevalence of vertebral fracture in women and the relationship with bone density and symptoms: the Chingford Study

scientific article published on 01 July 1993

Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk

article

Progression of Central Pulse Pressure Over 1 Decade of Aging and its Reversal by Nitroglycerin

artículo científico publicado el 31 de enero de 2012

Progression of lumbar disc degeneration over a decade: a heritability study

artículo científico publicado en 2011

Proopiomelanocortin gene variants are associated with serum leptin and body fat in a normal female population

artículo científico publicado en 2005

Protective effect of androgens against inflammation induced cartilage degradation in male rodents

artículo científico publicado en 1993

Protein tyrosine phosphatase-1B gene PTPN1: selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population

artículo científico publicado en 2005

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Proton pump inhibitors alter the composition of the gut microbiota

artículo científico publicado en 2016

Publisher Correction: Building an international consortium for tracking coronavirus health status

artículo científico publicado en 2020

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

artículo científico publicado en 2019

Publisher Correction: Human postprandial responses to food and potential for precision nutrition

artículo científico publicado en 2020

Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

QT interval in twins

artículo científico publicado en 2000

Quantifying additional COVID-19 symptoms will save lives

scientific article published on 04 June 2020

Quantifying the degree of sharing of genetic and non-genetic causes of gene expression variability across four tissues

article

Quantitative genetics of circulating Dickkopf-related protein 1 (DKK1) in community-based sample of UK twins

artículo científico publicado en 2016

Quantitative linkage analysis for pancreatic B-cell function and insulin resistance in a large twin cohort

artículo científico publicado en 2008

Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control

artículo científico publicado en 2009

Quantitative trait loci for bone lengths on chromosome 5 using dual energy X-Ray absorptiometry imaging in the Twins UK cohort

artículo científico publicado en 2008

Quantitative trait locus on chromosome 8q influences the switch from fetal to adult hemoglobin.

artículo científico publicado en 2004

Quantitative variability of 342 plasma proteins in a human twin population

artículo científico publicado en 2015

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

artículo científico publicado en 2023

Race, ethnicity, community-level socioeconomic factors, and risk of COVID-19 in the United States and the United Kingdom

artículo científico publicado en 2021

Radiographic assessment of osteoarthritis in population studies: whither Kellgren and Lawrence?

artículo científico publicado en 1993

Radiographic criteria for epidemiologic studies of osteoarthritis

artículo científico publicado en 1995

Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts

artículo científico publicado en 2008

Radiographic progression of lumbar spine disc degeneration is influenced by variation at inflammatory genes: a candidate SNP association study in the Chingford cohort

artículo científico publicado en 2005

Radiological progression of osteoarthritis: an 11 year follow up study of the knee

artículo científico publicado el 1 de octubre de 1992

Randomised, controlled trial of avocado–soybean unsaponifiable (Piascledine) effect on structure modification in hip osteoarthritis: the ERADIAS study

artículo científico publicado el 23 de enero de 2013

Rapid implementation of mobile technology for real-time epidemiology of COVID-19

scientific article published on 05 May 2020

Rapid implementation of mobile technology for real-time epidemiology of COVID-19

artículo científico publicado en 2020

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Re: Age of death of parents for patients with RA.

artículo científico publicado en 1990

Real-time tracking of self-reported symptoms to predict potential COVID-19

scientific article published on 11 May 2020

Recent advances in the genetics of osteoporosis.

artículo científico publicado en 2006

Recent and Lifelong Sexual Dysfunction in a Female UK Population Sample: Prevalence and Risk Factors

artículo científico publicado el 15 de junio de 2011

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium

artículo científico publicado en 2010

Recommendations for the registration of drugs used in the treatment of osteoarthritis: an update on biochemical markers

artículo científico publicado en 2001

Red Wine Consumption Associated With Increased Gut Microbiota α-Diversity in 3 Independent Cohorts

scientific article published on 28 August 2019

Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration

artículo científico publicado en 2006

Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study

artículo científico publicado en 2006

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

artículo científico publicado en 2018

Relation between Heberden’s nodes and distal interphalangeal joint osteophytes and their role as markers of generalised disease

artículo científico publicado el 1 de abril de 1998

Relation between insulin-like growth factor-I concentrations, osteoarthritis, bone density, and fractures in the general population: the Chingford study

artículo científico publicado en 1996

Relation of arterial stiffness to left ventricular structure and function in healthy women

artículo científico publicado en 2018

Relation of birth weight, body mass index, and change in size from birth to adulthood to insulin resistance in a female twin cohort

artículo científico publicado en 2007

Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate

artículo científico publicado en 2007

Relationship between dry eye symptoms and pain sensitivity.

artículo científico publicado en 2013

Relationship between genome and epigenome--challenges and requirements for future research

artículo científico publicado en 2014

Repeated measures of intraocular pressure result in higher heritability and greater power in genetic linkage studies

artículo científico publicado en 2009

Replication of psychometric properties of the FSFI and validation of a modified version (FSFI-LL) assessing lifelong sexual function in an unselected sample of females.

artículo científico publicado en 2010

Reply

Reproducibility and sensitivity to change of various methods to measure joint space width in osteoarthritis of the hip: a double reading of three different radiographic views taken with a three-year interval

artículo científico publicado en 2005

Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women.

artículo científico publicado en 2006

Research gaps and opportunities in precision nutrition: an NIH workshop report

artículo científico publicado en 2022

Response to: The Microbiome: A Biological Mechanism Underpinning the Social Gradient of Musculoskeletal Conditions

artículo científico publicado en 2016

Returns to Education: Evidence from U.K. Twins

article

Rheumatoid arthritis, diabetes, and schizophrenia

scientific article published on 01 January 1990

Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthri

artículo científico publicado en 2006

Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study

artículo científico publicado en 2022

Risk factors for osteoarthritis in the tibiofemoral and patellofemoral joints of the knee

scientific article published on 01 June 1997

Risk factors for osteoarthritis: genetics

artículo científico publicado en 2004

Risk factors for progression of lumbar spine disc degeneration: the Chingford Study

artículo científico publicado en 2003

Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study

artículo científico publicado en 2020

Risk of COVID-19 among frontline healthcare workers and the general community: a prospective cohort study

scientific article published on 05 May 2020

Risk of Premature Ovarian Failure in Twins

article published in 2005

Risk of Wrist Fracture in Women Is Heritable and Is Influenced by Genes That Are Largely Independent of Those Influencing BMD

article

Risk of Wrist Fracture in Women Is Heritable and Is Influenced by Genes That Are Largely Independent of Those Influencing BMD

artículo científico publicado en 2004

Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2

artículo científico publicado en 2022

Risk of osteoarthritis associated with long-term weight-bearing sports: a radiologic survey of the hips and knees in female ex-athletes and population controls

artículo científico publicado en 1996

Risk of vertebral fracture in women with rheumatoid arthritis

artículo científico publicado en 1993

Robust, reproducible clinical patterns in hospitalised patients with COVID-19

artículo científico publicado en 2020

Role and evolution of therapeutic options

artículo científico publicado en 1996

Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain

artículo científico publicado en 2010

Role of the gut microbiome for cancer patients receiving immunotherapy: Dietary and treatment implications

artículo científico publicado en 2020

Role of the gut microbiota in nutrition and health.

artículo científico publicado en 2018

SARS-CoV-2 (COVID-19) infection in pregnant women: characterization of symptoms and syndromes predictive of disease and severity through real-time, remote participatory epidemiology

artículo científico publicado en 2020

SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women

artículo científico publicado en 2007

SMAD3 is associated with the total burden of radiographic osteoarthritis: the Chingford study

artículo científico publicado en 2014

SNPs associated withHHIPexpression have differential effects on lung function in males and females

Safety and efficacy of the cathepsin K inhibitor ONO-5334 in postmenopausal osteoporosis: the OCEAN study

artículo científico publicado en 2011

Safety of hormone replacement therapy (HRT) in systemic lupus erythematosus (SLE)

artículo científico publicado en 1994

Salt-inducible kinase 3, SIK3, is a new gene associated with hearing

artículo científico publicado en 2014

Same genetic components underlie different measures of sweet taste preference

artículo científico publicado en 2007

Schmorl's nodes: common, highly heritable, and related to lumbar disc disease.

artículo científico publicado en 2007

Self-Reported Symptoms of COVID-19, Including Symptoms Most Predictive of SARS-CoV-2 Infection, Are Heritable

artículo científico publicado en 2020

Self-reported symptoms of covid-19 including symptoms most predictive of SARS-CoV-2 infection, are heritable

artículo científico publicado en 2020

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

artículo científico publicado en 2010

Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

artículo científico publicado en 2014

Serum Lipid Levels and Risk Of Hand Osteoarthritis: The Chingford Prospective Cohort Study

artículo científico publicado en 2017

Serum adiponectin and bone mineral density in women

artículo científico publicado en 2007

Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis

artículo científico publicado en 2010

Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women.

artículo científico publicado en 2016

Serum concentrations of sex hormone binding globulin in lung cancer

Serum creatinine and fat-free mass (lean body mass)

artículo científico publicado en 2000

Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes

artículo científico publicado en 2020

Session 1: Epidemiology and genetics of hand osteoarthritis

article

Seventy-five genetic loci influencing the human red blood cell

artículo científico publicado en 2012

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

artículo científico publicado en 2014

Sex and ethnic differences in the association ofASPN,CALM1,COL2A1,COMP, andFRZB with genetic susceptibility to osteoarthritis of the knee

article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome.

artículo científico publicado en 2016

Should healthy people take a vitamin D supplement in winter months?

artículo científico publicado en 2016

Sibship size does not increase the risk of developing rheumatoid arthritis

artículo científico publicado en 1992

Signatures of early frailty in the gut microbiota

artículo científico publicado en 2016

Significant differences in UK and US female bone density reference ranges.

artículo científico publicado en 2010

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases

artículo científico publicado en 2012

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

artículo científico publicado en 2015

Size at birth, adult intestinal calcium absorption and 1,25(OH)(2) vitamin D.

artículo científico publicado en 2002

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

artículo científico publicado en 2018

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

Snack quality and snack timing are associated with cardiometabolic blood markers: the ZOE PREDICT study

artículo científico publicado en 2023

Socioeconomic Status and the Gut Microbiome: A TwinsUK Cohort Study

artículo científico publicado en 2019

Somatic point mutations occurring early in development: a monozygotic twin study.

artículo científico publicado en 2013

Spiking of the tibial tubercles--a radiological feature of osteoarthritis?

artículo científico publicado en 1996

Statins as modulators of bone formation

artículo científico publicado en 2002

Steroid osteoporosis

scientific article published on 01 August 1993

Strain-Level Analysis of Bifidobacterium spp. from Gut Microbiomes of Adults with Differing Lactase Persistence Genotypes

artículo científico publicado en 2020

Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia

artículo científico publicado en 2008

Structural, psychological, and genetic influences on low back and neck pain: A study of adult female twins

scientific article published on 01 April 2004

Subclinical deformities of the hip are significant predictors of radiographic osteoarthritis and joint replacement in women. A 20 year longitudinal cohort study.

artículo científico publicado en 2014

Symptom clusters in COVID-19: A potential clinical prediction tool from the COVID Symptom Study app

artículo científico publicado en 2021

Symptom clusters in Covid19: A potential clinical prediction tool from the COVID Symptom study app

artículo científico publicado en 2020

Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts

artículo científico publicado en 2021

TUB is a candidate gene for late-onset obesity in women

artículo científico publicado en 2007

Targeted metabolomics profiles are strongly correlated with nutritional patterns in women

artículo científico publicado en 2012

Telomere length in circulating leukocytes is associated with lung function and disease.

artículo científico publicado en 2013

Telomere length in leukocytes correlates with bone mineral density and is shorter in women with osteoporosis

artículo científico publicado en 2007

Telomeres and the natural lifespan limit in humans

artículo científico publicado en 2017

Ten Hour Time-Restricted Eating (TRE) Is Associated with Improvements in Energy, Mood, Hunger and Weight in Free-Living Settings: The ZOE BIG IF Study

The 7Q31 locus, containing WNT16, is associated with bone mineral density, osteoporotic fracture and bone strength

The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits

artículo científico publicado en 2015

The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins

artículo científico publicado en 2019

The COronavirus Pandemic Epidemiology (COPE) Consortium: A Call to Action

scientific article published on 05 May 2020

The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium

artículo científico publicado en 2015

The Contribution of Genes to Osteoarthritis

article

The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males

artículo científico publicado en 2013

The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance

artículo científico publicado en 2010

The Genetic Architecture of Gene Expression in Peripheral Blood

artículo científico publicado en 2016

The Genetic Architecture of Gene Expression in Peripheral Blood

artículo científico publicado en 2017

The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans

artículo científico publicado en 2007

The Heritability of Corneal Hysteresis and Ocular Pulse Amplitude

scientific article published on 24 April 2008

The Identification of Hereditary and Environmental Determinants of Frailty in a Cohort of UK Twins

artículo científico publicado en 2016

The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis

artículo científico publicado en 2011

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Microbiome and Musculoskeletal Conditions of Aging: A Review of Evidence for Impact and Potential Therapeutics

artículo científico publicado en 2015

The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study

artículo científico publicado en 2016

The SH2B gene is associated with serum leptin and body fat in normal female twins.

artículo científico publicado en 2007

The St. Thomas' UK Adult Twin Registry

artículo científico publicado en 2002

The St. Thomas' UK Adult Twin Registry

scholarly article by Tim D. Spector & Alex J. MacGregor published October 2002 in Twin Research and Human Genetics

The Three-Factor Eating Questionnaire, body mass index, and responses to sweet and salty fatty foods: a twin study of genetic and environmental associations

artículo científico publicado en 2008

The UK Adult Twin Registry (TwinsUK Resource)

artículo científico publicado en 2012

The UK Adult Twin Registry (TwinsUK)

article by Tim Spector & Frances M. K. Williams published 1 December 2006 in CrossRef Listing of Deleted DOIs

The Urinary Tract Microbiome in Older Women Exhibits Host Genetic and Environmental Influences

artículo científico publicado en 2020

The additive effect of individual genes in predicting risk of knee osteoarthritis

artículo científico publicado en 2007

The age-dependency of genetic and environmental influences on serum cytokine levels: a twin study

artículo científico publicado en 2012

The architecture of gene regulatory variation across multiple human tissues: the MuTHER study

artículo científico publicado en 2011

The assessment of vertebral deformity: a method for use in population studies and clinical trials

scientific article published on 01 May 1993

The association between hip morphology parameters and nineteen-year risk of end-stage osteoarthritis of the hip: a nested case-control study

artículo científico publicado en 2011

The association between low birth weight, childhood recollections of parental response to illness, and irritable bowel syndrome: a twin study

artículo científico publicado en 2020

The association between osteoarthritis and osteoporotic fracture: the Chingford Study

artículo científico publicado en 1996

The association of body mass index and osteoarthritis of the knee joint: an examination of genetic and environmental influences

artículo científico publicado en 2003

The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting

artículo científico publicado en 2001

The clinical relevance of genetic susceptibility to osteoarthritis

scientific article published on February 2010

The contribution of genes to osteoarthritis

artículo científico publicado en 2008

The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments?

artículo científico publicado en 2013

The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study

artículo científico publicado en 2013

The effect of genome-wide association scan quality control on imputation outcome for common variants

artículo científico publicado en 2011

The effect of moderate alcohol consumption on bone mineral density: a study of female twins.

artículo científico publicado en 2004

The effect of rheumatoid arthritis and steroid therapy on bone density in postmenopausal women

scientific article published on 01 November 1993

The effect of weight-bearing exercise on bone mineral density: a study of female ex-elite athletes and the general population

artículo científico publicado en 1996

The effects of 10 weeks military training on heel ultrasound and bone turnover

artículo científico publicado en 1999

The effects of social status on biological aging as measured by white-blood-cell telomere length

artículo científico publicado en 2006

The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis

artículo científico publicado en 2004

The etiological relationship between anxiety sensitivity, sexual distress, and female sexual dysfunction is partly genetically moderated.

artículo científico publicado en 2012

The fecal metabolome as a functional readout of the gut microbiome

article

The first "classical" twin study? Analysis of refractive error using monozygotic and dizygotic twins published in 1922

scientific article published on 01 June 2005

The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation

artículo científico publicado en 2012

The genetic and environmental structure of the covariation among the symptoms of insomnia, fatigue, and depression in adult females.

artículo científico publicado en 2012

The genetic architecture of the human immune system: a bioresource for autoimmunity and disease pathogenesis

artículo científico publicado en 2015

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetic contribution to carpal tunnel syndrome in women: a twin study

artículo científico publicado en 2002

The genetic contribution to hip joint morphometry and relationship to hip cartilage thickness

artículo científico publicado en 2001

The genetic contribution to radiographic hip osteoarthritis in women: results of a classic twin study

artículo científico publicado en 2000

The genetic epidemiology of joint hypermobility: A population study of female twins

artículo científico publicado en 2004

The genetic epidemiology of osteoarthritis

scientific article published on March 2010

The genetic influence on radiographic osteoarthritis is site specific at the hand, hip and knee

scientific article published on 19 January 2009

The genetics and epidemiology of female sexual dysfunction: a review.

artículo científico publicado en 2008

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The genetics of coronary heart disease: the contribution of twin studies

artículo científico publicado en 2003

The genetics of haemostasis: a twin study

scientific article published on 01 January 2001

The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation

artículo científico publicado en 2021

The gut microbiome, health and personalised nutrition

artículo científico publicado en 2022

The heritability of age-related cortical cataract: the twin eye study.

artículo científico publicado en 2001

The heritability of bone mineral density, ultrasound of the calcaneus and hip axis length: a study of postmenopausal twins

artículo científico publicado en 1996

The heritability of macular response to supplemental lutein and zeaxanthin: a classic twin study

artículo científico publicado en 2012

The heritability of optic disc parameters: a classic twin study

scientific article published on 01 January 2008

The heritability of plasma homocysteine, and the influence of genetic variation in the homocysteine methylation pathway

artículo científico publicado en 2007

The heritability of polymorphic light eruption

artículo científico publicado en 2000

The heritable determinants of cartilage oligomeric matrix protein

artículo científico publicado en 2006

The human gut and groundwater harbor non-photosynthetic bacteria belonging to a new candidate phylum sibling to Cyanobacteria

artículo científico publicado en 2013

The incidence and characteristics of accelerated knee osteoarthritis among women: the Chingford cohort

scientific article published on 31 January 2020

The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in women.

artículo científico publicado en 2002

The inheritance of peripapillary atrophy

artículo científico publicado en 2007

The interaction of genes and smoking on forced expiratory volume: a classic twin study

artículo científico publicado en 2007

The molecular genetic architecture of self-employment

artículo científico publicado en 2013

The narrow-sense and common single nucleotide polymorphism heritability of early repolarization

The natural history of radiographic knee osteoarthritis: a fourteen-year population-based cohort study.

artículo científico publicado en 2012

The pill, parity, and rheumatoid arthritis

article

The pleasure principle

artículo científico publicado en 2007

The power of genetic diversity in genome-wide association studies of lipids

The prebiotic effects of omega-3 fatty acid supplementation: A six-week randomised intervention trial

artículo científico publicado en 2021

The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue

artículo científico publicado en 2013

The progression of radiological hand osteoarthritis over ten years: a clinical follow-up study

artículo científico publicado en 1994

The rate of nonallelic homologous recombination in males is highly variable, correlated between monozygotic twins and independent of age

artículo científico publicado en 2014

The relation between insulin resistance and hemostasis: pleiotropic genes and common environment

artículo científico publicado en 2003

The relation between progressive osteoarthritis of the knee and long term progression of osteoarthritis of the hand, hip, and lumbar spine

artículo científico publicado en 2005

The relationship between DXA-based and anthropometric measures of visceral fat and morbidity in women

artículo científico publicado en 2013

The relationship between osteoarthritis and osteoporosis in the general population: the Chingford Study

artículo científico publicado en 1994

The relationship between retinal arteriolar and venular calibers is genetically mediated, and each is associated with risk of cardiovascular disease

artículo científico publicado en 2011

The relationship between same-sex sexual experience, sexual distress, and female sexual dysfunction.

artículo científico publicado en 2011

The relationship of bone density and fracture to incident and progressive radiographic osteoarthritis of the knee: the Chingford Study

artículo científico publicado en 2002

The relationship of joint hypermobility, bone mineral density, and osteoarthritis in the general population: the Chingford Study.

artículo científico publicado en 2003

The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study

artículo científico publicado en 1993

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

artículo científico publicado en 2013

The role of bone metabolism in osteoarthritis

artículo científico publicado en 2003

The role of heredity in determining central retinal thickness.

artículo científico publicado en 2007

The role of pregnancy in the course and aetiology of rheumatoid arthritis

artículo científico publicado en 1992

The role of serum TGF-beta isoforms as potential markers of osteoporosis

scientific article published on 01 January 1999

The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes

artículo científico publicado en 2012

The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits

artículo científico publicado en 2011

The use of radiographs in assessing the severity of knee osteoarthritis

artículo científico publicado en 1991

The use of the twin model to investigate the genetics and epigenetics of skin diseases with genomic, transcriptomic and methylation data

artículo científico publicado el 14 de enero de 2012

The virome in adult monozygotic twins with concordant or discordant gut microbiomes

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

artículo científico publicado en 2010

Tim Spector: Butter or margarine? Food religion challenged

artículo científico publicado en 2019

Time-dependent genetic effects on gene expression implicate aging processes

artículo científico publicado en 2017

Tobacco smoking and oestrogen replacement are associated with lower total and central fat in monozygotic twins

artículo científico publicado el 1 de febrero de 1998

Traduction française des recommandations de l’Osteoarthritis Research Society International (OARSI) sur la prise en charge de la gonarthrose et de la coxarthrose

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

scientific article published on 21 December 2018

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

artículo científico publicado en 2009

Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets

Twin studies advance the understanding of gene-environment interplay in human nutrigenomics

artículo científico publicado en 2014

Twins and the genetic architecture of osteoarthritis

artículo científico publicado en 1999

Twins. Novel uses to study complex traits and genetic diseases.

artículo científico publicado en 2000

Twins: A cloning experience

artículo científico publicado en 2006

TwinsUK: The UK Adult Twin Registry Update

artículo científico publicado en 2019

Two candidate genes for low platelet count identified in an Asian Indian kindred by genome-wide linkage analysis: glycoprotein IX and thrombopoietin

artículo científico publicado en 2006

Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota

artículo científico publicado en 2018

UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.

artículo científico publicado en 2015

UNCOVERING ASSOCIATIONS BETWEEN BLOOD PRESSURE PHENOTYPES AND IMMUNE TRAITS IN TWINSUK

artículo científico publicado en 2021

Understanding coronary artery disease using twin studies

artículo científico publicado en 2012

Untangling the relationship between diet and visceral fat mass through blood metabolomics and gut microbiome profiling

artículo científico publicado en 2017

Urinary collagen crosslinks reflect the radiographic severity of knee osteoarthritis

artículo científico publicado en 1992

Use of dietary indices to control for diet in human gut microbiota studies

artículo científico publicado en 2018

Use of thermographic criteria to identify Raynaud's phenomenon in a population setting.

artículo científico publicado en 2003

Uses of the Twins UK genetic database

scientific article published on 01 November 2007

Using epigenome-wide association scans of DNA methylation in age-related complex human traits

artículo científico

Using epigenomic studies in monozygotic twins to improve our understanding of cancer.

artículo científico publicado en 2014

Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study

artículo científico publicado en 2021

Validation of statistical shape modelling to predict hip osteoarthritis in females: data from two prospective cohort studies (Cohort Hip and Cohort Knee and Chingford).

artículo científico publicado en 2015

Validity of continuous glucose monitoring for categorizing glycemic responses to diet: implications for use in personalized nutrition

artículo científico publicado en 2022

Variance components models for physical activity with age as modifier: a comparative twin study in seven countries

artículo científico publicado en 2011

Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model.

artículo científico publicado en 2011

Variants associated with expression have sex-differential effects on lung function

artículo científico publicado en 2020

Variants close to NTRK2 gene are associated with birth weight in female twins

artículo científico publicado en 2014

Variants in MTNR1B influence fasting glucose levels

artículo científico publicado en 2008

Variation and Heritability in Hair Diameter and Curvature in an Australian Twin Sample

artículo científico publicado en 2016

Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women.

artículo científico publicado en 2009

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease

artículo científico publicado en 2021

Variations in genome-wide gene expression in identical twins - a study of primary osteoblast-like culture from female twins discordant for osteoporosis

artículo científico publicado en 2004

Virome Diversity Correlates with Intestinal Microbiome Diversity in Adult Monozygotic Twins

scientific article published on 01 February 2019

Vitamin D receptor genotype and bone mineral density: Authors’ reply

artículo científico publicado en 1995

Vitamin-D-receptor-gene polymorphism and bone loss

artículo científico publicado en 1995

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

artículo científico publicado en 2012

What happens to patients with rheumatoid arthritis? The long-term outcome of treatment

artículo científico publicado en 1988

What should we hope to achieve when treating rheumatoid arthritis?

artículo científico publicado en 1989

When is a replication not a replication? Or how to spot a good genetic association study

scientific article published on 01 April 2006

Where Did I Leave My Keys? A Twin Study of Self-Reported Memory Ratings Using the Multifactorial Memory Questionnaire

scientific article published on 01 April 2005

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

artículo científico publicado en 2014

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

artículo científico publicado en 2017

Whole-genome sequence-based analysis of thyroid function.

artículo científico publicado en 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

artículo científico publicado en 2015

Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

artículo científico publicado en 2017

Widespread smell testing for COVID-19 has limited application - Authors' reply

artículo científico publicado en 2020

Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome

artículo científico publicado en 2022

Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project

artículo científico publicado en 2015

[Radiological evaluation of osteoarthritis]

scientific article published on 01 December 1996

cMYB is involved in the regulation of fetal hemoglobin production in adults.

artículo científico publicado en 2006