Lista de obras - Alejandro Giorgetti - Dominio Público Uruguay

A Candidate Ion-Retaining State in the Inward-Facing Conformation of Sodium/Galactose Symporter: Clues from Atomistic Simulations.

artículo científico publicado en 2013

A Multimodal Approach for Protein Remote Homology Detection.

artículo científico publicado en 2015

A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications

artículo científico publicado en 2014

A homology model of the pore region of HCN channels.

artículo científico publicado en 2005

Advanced computational methods in molecular medicine

artículo científico publicado en 2012

Agonist Binding to Chemosensory Receptors: A Systematic Bioinformatics Analysis

artículo científico publicado en 2017

Apparent Mineralocorticoid Excess by a Novel Mutation and Epigenetic Modulation by HSD11B2 Promoter Methylation

artículo científico publicado en 2015

Automatic procedure for using models of proteins in molecular replacement.

artículo científico publicado en 2007

Bioinformatics Applications in Life Sciences and Technologies

artículo científico publicado en 2016

Characterization of C-S Lyase from C. diphtheriae: a possible target for new antimicrobial drugs

artículo científico publicado en 2013

Chemosensorial G-proteins-coupled receptors: a perspective from computational methods

artículo científico

Computational molecular biology approaches to ligand-target interactions.

artículo científico publicado en 2009

Conserved charged amino acids are key determinants for fatty acid binding proteins (FABPs)-membrane interactions. A multi-methodological computational approach.

artículo científico publicado en 2017

Dual binding mode of "bitter sugars" to their human bitter taste receptor target.

artículo científico publicado en 2019

Dynamic characterization and substrate binding of cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase-an enzyme used in bioremediation

artículo científico publicado en 2014

Effect of the Heteroaromatic Antenna on the Binding of Chiral Eu(III) Complexes to Bovine Serum Albumin

scientific article published on 10 August 2020

Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T.

artículo científico publicado en 2016

Evaluating the usefulness of protein structure models for molecular replacement.

artículo científico publicado en 2005

Evidence for a Transient Additional Ligand Binding Site in the TAS2R46 Bitter Taste Receptor

artículo científico publicado en 2015

GOMoDo: A GPCRs online modeling and docking webserver

artículo científico publicado en 2013

Genetic and bioinformatics analysis of four novel GCK missense variants detected in Caucasian families with GCK-MODY phenotype.

artículo científico publicado en 2014

Genome-wide Membrane Protein Structure Prediction.

artículo científico publicado en 2013

Genome-wide characterisation and expression profile of the grapevine ATL ubiquitin ligase family reveal biotic and abiotic stress-responsive and development-related members.

artículo científico publicado en 2016

Hybrid molecular mechanics/coarse-grained simulations for structural prediction of G-protein coupled receptor/ligand complexes

artículo científico publicado en 2012

Identification of aldolase and ferredoxin reductase within the dbt operon of Burkholderia fungorum DBT1.

artículo científico publicado en 2013

Identification of novel mutations in hemochromatosis genes by targeted next generation sequencing in Italian patients with unexplained iron overload.

artículo científico publicado en 2016

Impact of Cholesterol on the Stability of Monomeric and Dimeric Forms of the Translocator Protein TSPO: A Molecular Simulation Study

scientific article published on 19 September 2020

Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor

artículo científico publicado en 2010

Locking CNGA1 channels in the open and closed state.

artículo científico publicado en 2006

Loss of the JAK2 intramolecular auto-inhibition mechanism is predicted by structural modelling of a novel exon 12 insertion mutation in a case of idiopathic erythrocytosis

artículo científico publicado en 2008

Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules

artículo científico publicado en 2014

Metal binding affinity and structural properties of calmodulin-like protein 14 from Arabidopsis thaliana

artículo científico publicado en 2016

Modelling and molecular dynamics of the interaction between the E3 ubiquitin ligase Itch and the E2 UbcH7.

artículo científico publicado en 2008

Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays

artículo científico publicado en 2016

Multi-scale simulations of membrane proteins: The case of bitter taste receptors

Mutation analysis of violaxanthin de-epoxidase identifies substrate-binding sites and residues involved in catalysis

artículo científico publicado en 2010

NMR Constraints Analyser: a web-server for the graphical analysis of NMR experimental constraints.

artículo científico publicado en 2010

Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of oriens-lacunosum moleculare interneurons.

artículo científico publicado en 2010

Orthosteric and benzodiazepine cavities of the α1β2γ2 GABAA receptor: Insights from experimentally-validated in silico methods.

artículo científico publicado en 2018

Predicting ligand binding poses for low-resolution membrane protein models: Perspectives from multiscale simulations

artículo científico publicado en 2018

Protein Aggregation and Molecular Crowding: Perspectives From Multiscale Simulations

artículo científico publicado en 2016

Residues in the Distal Heme Pocket of Arabidopsis Non-Symbiotic Hemoglobins: Implication for Nitrite Reductase Activity

artículo científico publicado en 2016

Role of Extracellular Loops and Membrane Lipids for Ligand Recognition in the Neuronal Adenosine Receptor Type 2A: An Enhanced Sampling Simulation Study

artículo científico publicado en 2018

Role of active-site residues Tyr55 and Tyr114 in catalysis and substrate specificity of Corynebacterium diphtheriae C-S lyase

artículo científico publicado en 2014

Site-directed enzymatic PEGylation of the human granulocyte colony-stimulating factor

artículo científico publicado en 2009

Structural Prediction of the Dimeric Form of the Mammalian Translocator Membrane Protein TSPO: A Key Target for Brain Diagnostics

scholarly article by Juan Zeng published in August 2018

Structural Requirements for Cooperativity in Ileal Bile Acid-binding Proteins

artículo científico publicado en 2011

Structural basis of gating of CNG channels

artículo científico publicado en 2005

Structural heterogeneity of the μ-opioid receptor's conformational ensemble in the apo state

artículo científico publicado en 2017

Structural modeling of G-protein coupled receptors: An overview on automatic web-servers

artículo científico publicado en 2016

Structural predictions of neurobiologically relevant G-protein coupled receptors and intrinsically disordered proteins

artículo científico

Structure/function relationships of phospholipases C Beta.

artículo científico publicado en 2013

The assessment of methods for protein structure prediction.

artículo científico publicado en 2008

The evaluation of protein structure prediction results.

artículo científico publicado en 2007

The implications of alternative splicing in the ENCODE protein complement

artículo científico publicado en 2007

Transient Interactions of a Cytosolic Protein with Macromolecular and Vesicular Cosolutes: Unspecific and Specific Effects.

artículo científico publicado en 2015

Unifying view of mechanical and functional hotspots across class A GPCRs.

artículo científico publicado en 2017

pyGOMoDo: GPCRs modeling and docking with python

artículo científico publicado en 2023

Lista de obras de Alejandro Giorgetti

A Candidate Ion-Retaining State in the Inward-Facing Conformation of Sodium/Galactose Symporter: Clues from Atomistic Simulations.

A Multimodal Approach for Protein Remote Homology Detection.

A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications

A homology model of the pore region of HCN channels.

Advanced computational methods in molecular medicine

Agonist Binding to Chemosensory Receptors: A Systematic Bioinformatics Analysis

Apparent Mineralocorticoid Excess by a Novel Mutation and Epigenetic Modulation by HSD11B2 Promoter Methylation

Automatic procedure for using models of proteins in molecular replacement.

Bioinformatics Applications in Life Sciences and Technologies

Characterization of C-S Lyase from C. diphtheriae: a possible target for new antimicrobial drugs

Chemosensorial G-proteins-coupled receptors: a perspective from computational methods

Computational molecular biology approaches to ligand-target interactions.

Conserved charged amino acids are key determinants for fatty acid binding proteins (FABPs)-membrane interactions. A multi-methodological computational approach.

Dual binding mode of "bitter sugars" to their human bitter taste receptor target.

Dynamic characterization and substrate binding of cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase-an enzyme used in bioremediation

Effect of the Heteroaromatic Antenna on the Binding of Chiral Eu(III) Complexes to Bovine Serum Albumin

Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T.

Evaluating the usefulness of protein structure models for molecular replacement.

Evidence for a Transient Additional Ligand Binding Site in the TAS2R46 Bitter Taste Receptor

GOMoDo: A GPCRs online modeling and docking webserver

Genetic and bioinformatics analysis of four novel GCK missense variants detected in Caucasian families with GCK-MODY phenotype.

Genome-wide Membrane Protein Structure Prediction.

Genome-wide characterisation and expression profile of the grapevine ATL ubiquitin ligase family reveal biotic and abiotic stress-responsive and development-related members.

Hybrid molecular mechanics/coarse-grained simulations for structural prediction of G-protein coupled receptor/ligand complexes

Identification of aldolase and ferredoxin reductase within the dbt operon of Burkholderia fungorum DBT1.

Identification of novel mutations in hemochromatosis genes by targeted next generation sequencing in Italian patients with unexplained iron overload.

Impact of Cholesterol on the Stability of Monomeric and Dimeric Forms of the Translocator Protein TSPO: A Molecular Simulation Study

Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor

Locking CNGA1 channels in the open and closed state.

Loss of the JAK2 intramolecular auto-inhibition mechanism is predicted by structural modelling of a novel exon 12 insertion mutation in a case of idiopathic erythrocytosis

Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules

Metal binding affinity and structural properties of calmodulin-like protein 14 from Arabidopsis thaliana

Modelling and molecular dynamics of the interaction between the E3 ubiquitin ligase Itch and the E2 UbcH7.

Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays

Multi-scale simulations of membrane proteins: The case of bitter taste receptors

Mutation analysis of violaxanthin de-epoxidase identifies substrate-binding sites and residues involved in catalysis

NMR Constraints Analyser: a web-server for the graphical analysis of NMR experimental constraints.

Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of oriens-lacunosum moleculare interneurons.

Orthosteric and benzodiazepine cavities of the α1β2γ2 GABAA receptor: Insights from experimentally-validated in silico methods.

Predicting ligand binding poses for low-resolution membrane protein models: Perspectives from multiscale simulations

Protein Aggregation and Molecular Crowding: Perspectives From Multiscale Simulations

Residues in the Distal Heme Pocket of Arabidopsis Non-Symbiotic Hemoglobins: Implication for Nitrite Reductase Activity

Role of Extracellular Loops and Membrane Lipids for Ligand Recognition in the Neuronal Adenosine Receptor Type 2A: An Enhanced Sampling Simulation Study

Role of active-site residues Tyr55 and Tyr114 in catalysis and substrate specificity of Corynebacterium diphtheriae C-S lyase

Site-directed enzymatic PEGylation of the human granulocyte colony-stimulating factor

Structural Prediction of the Dimeric Form of the Mammalian Translocator Membrane Protein TSPO: A Key Target for Brain Diagnostics

Structural Requirements for Cooperativity in Ileal Bile Acid-binding Proteins

Structural basis of gating of CNG channels

Structural heterogeneity of the μ-opioid receptor's conformational ensemble in the apo state

Structural modeling of G-protein coupled receptors: An overview on automatic web-servers

Structural predictions of neurobiologically relevant G-protein coupled receptors and intrinsically disordered proteins

Structure/function relationships of phospholipases C Beta.

The assessment of methods for protein structure prediction.

The evaluation of protein structure prediction results.

The implications of alternative splicing in the ENCODE protein complement

Transient Interactions of a Cytosolic Protein with Macromolecular and Vesicular Cosolutes: Unspecific and Specific Effects.

Unifying view of mechanical and functional hotspots across class A GPCRs.

pyGOMoDo: GPCRs modeling and docking with python