Lista de obras - Friedemann Kiefer - Dominio Público Uruguay

A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level

artículo científico publicado en 2015

A novel model for ectopic, chronic, intravital multiphoton imaging of bone marrow vasculature and architecture in split femurs

artículo científico publicado en 2015

A qualitative comparison of ten tissue clearing techniques

artículo científico publicado en 2017

Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.

artículo científico publicado en 2005

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death

artículo científico publicado en 2005

Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state

artículo científico publicado en 2012

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation

artículo científico publicado en 2017

B cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1

artículo científico publicado en 2001

CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules

scientific article published on 23 November 2011

Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes

artículo científico publicado en 2007

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB

scientific article published on 29 January 2001

Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2.

artículo científico publicado en 2015

Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function

artículo científico publicado en 2017

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

artículo científico publicado en 2021

Distinct roles of VE-cadherin for development and maintenance of specific lymph vessel beds

article

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

scientific journal article

Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.

artículo científico publicado en 1994

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

artículo científico publicado en 2015

Fusing VE-cadherin to α-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation

artículo científico publicado en 2014

Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection

artículo científico publicado en 1997

HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion

artículo científico publicado en 2010

HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion

artículo científico publicado en 2010

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

artículo científico publicado en 2000

Hematopoietic progenitor kinase 1 (HPK1) is required for LFA-1-mediated neutrophil recruitment during the acute inflammatory response

artículo científico publicado en 2013

Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response

artículo científico publicado en 2009

Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation

artículo científico publicado en 2009

Identification of a clonally expanding haematopoietic compartment in bone marrow

artículo científico publicado en 2012

Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse

artículo científico

Introductory remarks

scientific article published on 01 January 2014

Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.

artículo científico publicado en 2018

Maturation of Platelet Function During Murine Fetal Development In Vivo.

artículo científico publicado en 2017

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation

artículo científico publicado en 2012

Migration inhibition of mammary epithelial cells by Syk is blocked in the presence of DDR1 receptors

artículo científico publicado en 2011

Modulation of synaptic function through the α-neurexin-specific ligand neurexophilin-1.

artículo científico publicado en 2014

Multiple roles of lymphatic vessels in peripheral lymph node development

artículo científico publicado en 2018

Novel components of mammalian stress-activated protein kinase cascades

artículo científico publicado en 1997

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells

scholarly article

Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development

artículo científico publicado en 2015

Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures

artículo científico publicado en 2021

Receptor tyrosine kinase inhibitors: Are they real tumor killers?

artículo científico publicado en 2015

Regulation of developmental lymphangiogenesis by Syk(+) leukocytes

artículo científico publicado en 2010

SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1

artículo científico publicado en 1997

ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation

artículo científico publicado en 2001

Signal transduction and co-stimulatory pathways

artículo científico publicado en 2002

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

artículo científico publicado en 2011

Statistical Permutation-based Artery Mapping (SPAM): a novel approach to evaluate imaging signals in the vessel wall.

artículo científico publicado en 2017

Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms

artículo científico publicado en 2014

Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation

artículo científico publicado en 2006

Synergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.

artículo científico publicado en 2001

Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization

artículo científico publicado en 2015

The BAFFling function of Syk in B-cell homeostasis

artículo científico publicado en 2015

The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction

artículo científico publicado en 2016

The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10.

artículo científico publicado en 2018

The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis

artículo científico publicado en 2015

The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity

artículo científico publicado en 2003

The role of chemokines and their receptors in angiogenesis

artículo científico publicado en 2011

The role of fatty acid β-oxidation in lymphangiogenesis

artículo científico publicado en 2016

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy

artículo científico publicado en 2014

Tissue clearing may alter emission and absorption properties of common fluorophores

artículo científico publicado en 2022

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

artículo científico publicado en 2016

Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation

artículo científico publicado en 2017

VE-PTP controls blood vessel development by balancing Tie-2 activity

artículo científico publicado en 2009

VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations

artículo científico publicado en 2017

Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities

artículo científico publicado en 2021

Visualization of lymphatic vessel development, growth, and function

artículo científico

Lista de obras de Friedemann Kiefer

A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level

A novel model for ectopic, chronic, intravital multiphoton imaging of bone marrow vasculature and architecture in split femurs

A qualitative comparison of ten tissue clearing techniques

Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death

Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation

B cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1

CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules

Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB

Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2.

Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

Distinct roles of VE-cadherin for development and maintenance of specific lymph vessel beds

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

Fusing VE-cadherin to α-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation

Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection

HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion

HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

Hematopoietic progenitor kinase 1 (HPK1) is required for LFA-1-mediated neutrophil recruitment during the acute inflammatory response

Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response

Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation

Identification of a clonally expanding haematopoietic compartment in bone marrow

Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse

Introductory remarks

Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.

Maturation of Platelet Function During Murine Fetal Development In Vivo.

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation

Migration inhibition of mammary epithelial cells by Syk is blocked in the presence of DDR1 receptors

Modulation of synaptic function through the α-neurexin-specific ligand neurexophilin-1.

Multiple roles of lymphatic vessels in peripheral lymph node development

Novel components of mammalian stress-activated protein kinase cascades

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells

Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development

Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures

Receptor tyrosine kinase inhibitors: Are they real tumor killers?

Regulation of developmental lymphangiogenesis by Syk(+) leukocytes

SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1

ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation

Signal transduction and co-stimulatory pathways

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

Statistical Permutation-based Artery Mapping (SPAM): a novel approach to evaluate imaging signals in the vessel wall.

Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms

Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation

Synergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.

Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization

The BAFFling function of Syk in B-cell homeostasis

The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction

The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10.

The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis

The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity

The role of chemokines and their receptors in angiogenesis

The role of fatty acid β-oxidation in lymphangiogenesis

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy

Tissue clearing may alter emission and absorption properties of common fluorophores

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation

VE-PTP controls blood vessel development by balancing Tie-2 activity

VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations

Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities

Visualization of lymphatic vessel development, growth, and function