Lista de obras - Laura Zaccaro - Dominio Público Uruguay

A Combined NMR and Computational Approach to Determine the RGDechi-hCit-αv β3 Integrin Recognition Mode in Isolated Cell Membranes

artículo científico publicado en 2015

A Novel Type of Zinc Finger DNA Binding Domain in theAgrobacteriumtumefaciensTranscriptional Regulator Ros†

artículo científico publicado en 2006

A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 β-like: from in silico identification to experimental evidence

artículo científico publicado en 2017

A new nerve growth factor-mimetic peptide active on neuropathic pain in rats

artículo científico publicado en 2008

A synthetic peptide reproducing the mitochondrial targeting motif of AKAP121: a conformational study

artículo científico publicado en 2004

AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress

artículo científico publicado en 2010

BB14, a Nerve Growth Factor (NGF)-like peptide shown to be effective in reducing reactive astrogliosis and restoring synaptic homeostasis in a rat model of peripheral nerve injury

artículo científico publicado en 2011

Chemical Modification for Proteolytic Stabilization of the Selective αvβ3 Integrin RGDechi Peptide: in Vitro and in Vivo Activities on Malignant Melanoma Cells.

artículo científico publicado en 2017

Conformational features of human melanin-concentrating hormone: an NMR and computational analysis

artículo científico publicado en 2003

Cullin3-BTB interface: a novel target for stapled peptides

artículo científico publicado en 2015

Deciphering the zinc coordination properties of the prokaryotic zinc finger domain: The solution structure characterization of Ros87 H42A functional mutant

artículo científico publicado en 2013

Design, synthesis and characterization of a peptide able to bind proteins of the KCTD family: implications for KCTD-cullin 3 recognition

artículo científico publicado en 2011

Evaluation of the anti-angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit

artículo científico publicado en 2011

Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting.

artículo científico publicado en 2012

Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5).

artículo científico publicado en 2009

Insights into the anticancer properties of the first antimicrobial peptide from Archaea.

artículo científico publicado en 2017

Mixed conformation in C?,?-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-Ome and Bz-Dph-Dph-Gly-Ome

artículo científico publicado en 1994

NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging.

artículo científico publicado en 2017

NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein

artículo científico publicado en 2003

Novel and Selective αvβ3Receptor Peptide Antagonist: Design, Synthesis, and Biological Behavior

artículo científico publicado en 2006

On-Bead Peptoid Dimerization Induced by Incorporation of Glycosylated Bridging Units in Submonomer Solid-Phase Approach to Glycopeptoids

scientific article published on 31 May 2019

Peptides for tumour therapy and diagnosis: current status and future directions.

scientific article published on January 2009

RGDechi-hCit: αvβ3 selective pro-apoptotic peptide as potential carrier for drug delivery into melanoma metastatic cells

artículo científico publicado en 2014

Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor.

artículo científico publicado en 2010

Selective Targeting of αvβ5 Integrin in HepG2 Cell Line by RGDechi15D Peptide

scientific article published on 19 September 2020

Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers.

artículo científico publicado en 2010

Straightforward entry to S-glycosylated fmoc-amino acids and their application to solid phase synthesis of glycopeptides and glycopeptidomimetics.

artículo científico publicado en 2015

Structural Zn(II) Implies a Switch from Fully Cooperative to Partly Downhill Folding in Highly Homologous Proteins

artículo científico publicado en 2013

Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitin

artículo científico publicado en 2014

Substitution of the Native Zn(II) with Cd(II), Co(II) and Ni(II) Changes the Downhill Unfolding Mechanism of Ros87 to a Completely Different Scenario

artículo científico publicado en 2020

Synthetic peptides mimicking the interleukin-6/gp 130 interaction: a two-helix bundle system. Design and conformational studies

scientific article published on 01 February 2003

TRPV1 modulators: structure-activity relationships using a rational combinatorial approach.

artículo científico publicado en 2011

The (unusual) aspartic acid in the metal coordination sphere of the prokaryotic zinc finger domain

artículo científico publicado en 2016

The prokaryotic Cys2His2 zinc-finger adopts a novel fold as revealed by the NMR structure of Agrobacterium tumefaciens Ros DNA-binding domain

artículo científico publicado en 2007

Therapeutic Potential of a Novel αβ₃ Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type

scientific article published on 24 January 2019

Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys₂ His₂ zinc finger induces structural rearrangements of typical DNA base determinant positions

artículo científico publicado en 2011

Zinc to cadmium replacement in the prokaryotic zinc-finger domain.

artículo científico

[99mTc][Tc(N)PNP43]-labeled RGD peptides as new probes for a selective detection of αvβ3 Integrin: synthesis, structure-activity and pharmacokinetic studies

scientific article published on 17 October 2018

Lista de obras de Laura Zaccaro

A Combined NMR and Computational Approach to Determine the RGDechi-hCit-αv β3 Integrin Recognition Mode in Isolated Cell Membranes

A Novel Type of Zinc Finger DNA Binding Domain in theAgrobacteriumtumefaciensTranscriptional Regulator Ros†

A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 β-like: from in silico identification to experimental evidence

A new nerve growth factor-mimetic peptide active on neuropathic pain in rats

A synthetic peptide reproducing the mitochondrial targeting motif of AKAP121: a conformational study

AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress

BB14, a Nerve Growth Factor (NGF)-like peptide shown to be effective in reducing reactive astrogliosis and restoring synaptic homeostasis in a rat model of peripheral nerve injury

Chemical Modification for Proteolytic Stabilization of the Selective αvβ3 Integrin RGDechi Peptide: in Vitro and in Vivo Activities on Malignant Melanoma Cells.

Conformational features of human melanin-concentrating hormone: an NMR and computational analysis

Cullin3-BTB interface: a novel target for stapled peptides

Deciphering the zinc coordination properties of the prokaryotic zinc finger domain: The solution structure characterization of Ros87 H42A functional mutant

Design, synthesis and characterization of a peptide able to bind proteins of the KCTD family: implications for KCTD-cullin 3 recognition

Evaluation of the anti-angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit

Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting.

Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5).

Insights into the anticancer properties of the first antimicrobial peptide from Archaea.

Mixed conformation in C?,?-disubstituted tripeptides: X-ray crystal structures of Z-Aib-Dph-Gly-Ome and Bz-Dph-Dph-Gly-Ome

NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging.

NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein

Novel and Selective αvβ3Receptor Peptide Antagonist: Design, Synthesis, and Biological Behavior

On-Bead Peptoid Dimerization Induced by Incorporation of Glycosylated Bridging Units in Submonomer Solid-Phase Approach to Glycopeptoids

Peptides for tumour therapy and diagnosis: current status and future directions.

RGDechi-hCit: αvβ3 selective pro-apoptotic peptide as potential carrier for drug delivery into melanoma metastatic cells

Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor.

Selective Targeting of αvβ5 Integrin in HepG2 Cell Line by RGDechi15D Peptide

Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers.

Straightforward entry to S-glycosylated fmoc-amino acids and their application to solid phase synthesis of glycopeptides and glycopeptidomimetics.

Structural Zn(II) Implies a Switch from Fully Cooperative to Partly Downhill Folding in Highly Homologous Proteins

Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitin

Substitution of the Native Zn(II) with Cd(II), Co(II) and Ni(II) Changes the Downhill Unfolding Mechanism of Ros87 to a Completely Different Scenario

Synthetic peptides mimicking the interleukin-6/gp 130 interaction: a two-helix bundle system. Design and conformational studies

TRPV1 modulators: structure-activity relationships using a rational combinatorial approach.

The (unusual) aspartic acid in the metal coordination sphere of the prokaryotic zinc finger domain

The prokaryotic Cys2His2 zinc-finger adopts a novel fold as revealed by the NMR structure of Agrobacterium tumefaciens Ros DNA-binding domain

Therapeutic Potential of a Novel αβ₃ Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type

Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys₂ His₂ zinc finger induces structural rearrangements of typical DNA base determinant positions

Zinc to cadmium replacement in the prokaryotic zinc-finger domain.

[99mTc][Tc(N)PNP43]-labeled RGD peptides as new probes for a selective detection of αvβ3 Integrin: synthesis, structure-activity and pharmacokinetic studies