Lista de obras - John Whittaker - Dominio Público Uruguay

A Bayesian toolkit for genetic association studies

artículo científico publicado en 2006

A Likelihood Ratio Approach to Family-based Association Studies with Covariates

artículo científico publicado en 2006

A Novel Protective Prion Protein Variant that Colocalizes with Kuru Exposure

artículo científico publicado en 2009

A comparison of Bayesian and frequentist approaches to incorporating external information for the prediction of prostate cancer risk

artículo científico publicado en 2012

A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy

artículo científico publicado en 2013

A likelihood ratio test for detecting patterns of disease-marker association

artículo científico publicado en 1997

A multi-SNP locus-association method reveals a substantial fraction of the missing heritability

artículo científico publicado en 2012

A variance components factor model for genetic association studies: a Bayesian analysis.

artículo científico publicado en 2010

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

artículo científico publicado en 2016

Age of onset and death in inherited prion disease are heritable

artículo científico publicado en 2009

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

artículo científico publicado en 2012

An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism

artículo científico publicado en 2009

Analysis of multiple SNPs in a candidate gene or region

artículo científico publicado en 2008

Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction

artículo científico publicado en 2010

Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals

artículo científico publicado en 2013

Application of the Lasso to Expression Quantitative Trait Loci Mapping

Are reported preterm birth rates reliable? An analysis of interhospital differences in the calculation of the weeks of gestation at delivery and preterm birth rate

article

Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia

artículo científico publicado en 2006

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

artículo científico publicado en 2011

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

artículo científico publicado en 2014

Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis

artículo científico publicado en 2013

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

artículo científico publicado en 2014

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Bayesian fine-scale mapping of disease loci, by hidden Markov models.

artículo científico publicado en 2000

Bayesian graphical models for genomewide association studies

artículo científico publicado en 2006

Bayesian meta-analysis of genetic association studies with different sets of markers

scientific article published on April 2008

Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables

artículo científico publicado en 2010

Bayesian modelling of multivariate quantitative traits using seemingly unrelated regressions

artículo científico publicado en 2005

Bayesian semiparametric meta-analysis for genetic association studies

artículo científico publicado en 2011

Blood pressure loci identified with a gene-centric array

artículo científico publicado en 2011

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males

artículo científico publicado en 2011

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

artículo científico publicado en 2013

Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants

artículo científico publicado en 2010

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

artículo científico publicado en 2012

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

artículo científico publicado en 2011

Comparison of methods and sampling designs to test for association between rare variants and quantitative traits

artículo científico publicado en 2011

Comparison of statistical tests for association between rare variants and binary traits

artículo científico publicado en 2012

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype

artículo científico publicado en 2012

Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation

artículo científico publicado en 2012

Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe.

artículo científico publicado en 2012

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

artículo científico publicado en 2011

Epigenetic signatures of Silver-Russell syndrome.

artículo científico publicado en 2010

Estimation and testing of parent-of-origin effects for quantitative traits

artículo científico publicado en 2003

Ethanol Intake and Risk of Lung Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Evaluation of folate metabolism gene polymorphisms as risk factors for open and closed neural tube defects

article

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D

artículo científico publicado en 2012

Evidence for an Interaction Between Familial Liability and Prenatal Exposure to Infection in the Causation of Schizophrenia

article

Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus

artículo científico publicado en 2010

Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study

article

Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus

artículo científico publicado en 2008

Family-based association analysis with ordered categorical phenotypes, covariates and interactions

article

Fine mapping of disease genes via haplotype clustering.

artículo científico publicado en 2006

Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach

artículo científico publicado en 2008

Fine-scale mapping of disease loci via shattered coalescent modeling of genealogies.

artículo científico publicado en 2002

Finite-sample properties of family-based association tests.

artículo científico publicado en 1999

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

artículo científico publicado en 2018

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

artículo científico publicado en 2011

Fregene: simulation of realistic sequence-level data in populations and ascertained samples

artículo científico publicado en 2008

Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy

artículo científico publicado en 2007

Gene-Centric Analysis Identifies Variants Associated With Interleukin-6 Levels and Shared Pathways With Other Inflammation Markers

article

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip

artículo científico publicado en 2013

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

artículo científico publicado en 2009

Genetic association analysis of vitamin D pathway with obesity traits.

artículo científico publicado en 2013

Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966

artículo científico publicado en 2009

Genetic factors in the pathogenesis of cholangiocarcinoma

artículo científico publicado en 2011

Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores

artículo científico publicado en 2013

Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study

artículo científico publicado en 2009

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip

artículo científico publicado en 2011

Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals

artículo científico publicado en 2010

Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals

artículo científico publicado en 2007

Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP

scientific journal article

Genome-wide association study of major recurrent depression in the U.K. population

artículo científico publicado en 2010

Genome-wide significance for dense SNP and resequencing data

artículo científico publicado en 2008

HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer

artículo científico publicado en 2011

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

artículo científico publicado en 2014

High-Dose Vitamin D Supplements Are Not Associated with Linear Growth in a Large Finnish Cohort

artículo científico publicado en 2011

IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma

artículo científico publicado en 2015

Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk

artículo científico publicado en 2006

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies

artículo científico publicado en 2012

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.

artículo científico publicado en 2005

Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip

artículo científico publicado en 2012

Ischaemic stroke subtypes and their genetic basis: a comprehensive meta-analysis of small and large vessel stroke

artículo científico publicado en 2008

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

artículo científico publicado en 2012

Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials

artículo científico publicado en 2006

Little loss of information due to unknown phase for fine-scale linkage-disequilibrium mapping with single-nucleotide-polymorphism genotype data.

artículo científico publicado en 2004

Marker-Assisted Selection and Introgression

Marker-assisted selection using ridge regression

article

Maternal Hb during pregnancy and offspring's educational achievement: a prospective cohort study over 30 years

artículo científico publicado en 2010

Maternal and Fetal Characteristics Associated With Meconium-Stained Amniotic Fluid

article

Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight

artículo científico publicado en 2012

Mendelian Randomisation study of the influence of eGFR on coronary heart disease

artículo científico publicado en 2016

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

artículo científico publicado en 2011

Multilocus Bayesian meta-analysis of gene-disease associations

artículo científico publicado en 2009

Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity

artículo científico publicado en 2003

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

artículo científico publicado en 2019

Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability

artículo científico publicado en 2011

On the Structural Differences Between Markers and Genomic AC Microsatellites

scientific article published on 01 May 2005

Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes.

artículo científico publicado en 2011

Performance of genotype imputation for rare variants identified in exons and flanking regions of genes

artículo científico publicado en 2011

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

artículo científico publicado en 2016

Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus

artículo científico publicado en 2003

Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus

artículo científico publicado en 2007

Polymorphisms in Natural Killer Cell Receptor Protein 2D (NKG2D) as a Risk Factor for Cholangiocarcinoma

artículo científico publicado en 2018

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

artículo científico publicado en 2013

Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial

artículo científico publicado en 2012

Power comparisons of the transmission/disequilibrium test and sib-transmission/disequilibrium-test statistics.

artículo científico publicado en 1999

Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer.

artículo científico publicado en 2008

Predictive models of choroidal neovascularization and geographic atrophy incidence applied to clinical trial design

artículo científico publicado en 2012

Racial variation in the association between gestational age and perinatal mortality: prospective study

artículo científico publicado en 2007

Reed Elsevier and the arms trade revisited

artículo científico publicado en 2007

Refinement of variant selection for the LDL cholesterol genetic risk score in the diagnosis of the polygenic form of clinical familial hypercholesterolemia and replication in samples from 6 countries

artículo científico publicado en 2014

Review of factors that influence the abundance of ions produced in a tandem mass spectrometer and statistical methods for discovering these factors

artículo científico publicado en 2009

SNP selection for association studies: maximizing power across SNP choice and study size.

artículo científico publicado en 2005

SNP subset selection for genetic association studies.

artículo científico publicado en 2003

Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease

artículo científico publicado en 2009

Sequence-level population simulations over large genomic regions

artículo científico publicado en 2007

Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations ⬇️

artículo científico publicado el 24 de mayo de 2011

Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies

artículo científico publicado en 2008

Sixty-five common genetic variants and prediction of type 2 diabetes

artículo científico publicado en 2014

Statistical design and analysis of pharmacogenetic trials

article

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits

artículo científico publicado en 2014

The benefits of using genetic information to design prevention trials

artículo científico publicado en 2013

The clonal evolution of metastases from primary serous epithelial ovarian cancers

artículo científico publicado en 2009

The effect of family structure on linkage tests using allelic association.

artículo científico publicado en 1998

The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults

artículo científico publicado en 2008

The impact of targeting all elderly persons in England and Wales for yearly influenza vaccination: excess mortality due to pneumonia or influenza and time trend study

artículo científico publicado en 2013

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

artículo científico publicado en 2012

The role and interaction of imprinted genes in human fetal growth

artículo científico publicado en 2015

The structure of interrupted human AC microsatellites

artículo científico publicado en 2003

The support of human genetic evidence for approved drug indications

artículo científico publicado en 2015

The use of Meta-Analysis Risk Estimates for Candidate Genes in Combination to Predict Coronary Heart Disease Risk

article

Timing of Planned Cesarean Delivery by Racial Group

article

Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

artículo científico publicado en 2013

Using information from both parents when testing for association between marker and disease loci

artículo científico publicado en 1998

Using statistical models to identify factors that have a role in defining the abundance of ions produced by tandem MS.

artículo científico publicado en 2007

Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies

artículo científico publicado en 2011

Lista de obras de John Whittaker

A Bayesian toolkit for genetic association studies

A Likelihood Ratio Approach to Family-based Association Studies with Covariates

A Novel Protective Prion Protein Variant that Colocalizes with Kuru Exposure

A comparison of Bayesian and frequentist approaches to incorporating external information for the prediction of prostate cancer risk

A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy

A likelihood ratio test for detecting patterns of disease-marker association

A multi-SNP locus-association method reveals a substantial fraction of the missing heritability

A variance components factor model for genetic association studies: a Bayesian analysis.

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

Age of onset and death in inherited prion disease are heritable

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism

Analysis of multiple SNPs in a candidate gene or region

Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction

Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals

Application of the Lasso to Expression Quantitative Trait Loci Mapping

Are reported preterm birth rates reliable? An analysis of interhospital differences in the calculation of the weeks of gestation at delivery and preterm birth rate

Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Bayesian fine-scale mapping of disease loci, by hidden Markov models.

Bayesian graphical models for genomewide association studies

Bayesian meta-analysis of genetic association studies with different sets of markers

Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables

Bayesian modelling of multivariate quantitative traits using seemingly unrelated regressions

Bayesian semiparametric meta-analysis for genetic association studies

Blood pressure loci identified with a gene-centric array

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

Comparison of methods and sampling designs to test for association between rare variants and quantitative traits

Comparison of statistical tests for association between rare variants and binary traits

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype

Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation

Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe.

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

Epigenetic signatures of Silver-Russell syndrome.

Estimation and testing of parent-of-origin effects for quantitative traits

Ethanol Intake and Risk of Lung Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Evaluation of folate metabolism gene polymorphisms as risk factors for open and closed neural tube defects

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D

Evidence for an Interaction Between Familial Liability and Prenatal Exposure to Infection in the Causation of Schizophrenia

Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus

Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study

Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus

Family-based association analysis with ordered categorical phenotypes, covariates and interactions

Fine mapping of disease genes via haplotype clustering.

Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach

Fine-scale mapping of disease loci via shattered coalescent modeling of genealogies.

Finite-sample properties of family-based association tests.

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

Fregene: simulation of realistic sequence-level data in populations and ascertained samples

Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy

Gene-Centric Analysis Identifies Variants Associated With Interleukin-6 Levels and Shared Pathways With Other Inflammation Markers

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

Genetic association analysis of vitamin D pathway with obesity traits.

Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966

Genetic factors in the pathogenesis of cholangiocarcinoma

Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores

Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip

Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals

Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals

Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP

Genome-wide association study of major recurrent depression in the U.K. population

Genome-wide significance for dense SNP and resequencing data

HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

High-Dose Vitamin D Supplements Are Not Associated with Linear Growth in a Large Finnish Cohort

IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma

Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies