Lista de obras - Jean-Jacques Letesson - Dominio Público Uruguay

3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum.

artículo científico publicado en 2018

A Brucella abortus cstA mutant is defective for association with endoplasmic reticulum exit sites and displays altered trafficking in HeLa cells

artículo científico publicado en 2012

A quorum-sensing regulator controls expression of both the type IV secretion system and the flagellar apparatus of Brucella melitensis

artículo científico publicado en 2005

Allergic Asthma Favors Growth in the Lungs of Infected Mice

artículo científico publicado en 2018

An RpoH-like heat shock sigma factor is involved in stress response and virulence in Brucella melitensis 16M

artículo científico publicado en 2006

Analysis of the antigen-specific IFN-γ producing T-cell subsets in cattle experimentally infected with Mycobacterium bovis

artículo científico publicado en 2002

Brucella Genital Tropism: What's on the Menu

artículo científico publicado en 2017

Brucella abortus Cell Cycle and Infection Are Coordinated

artículo científico publicado en 2015

Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains

artículo científico publicado en 2016

Brucella abortus depends on pyruvate phosphate dikinase and malic enzyme but not on Fbp and GlpX fructose-1,6-bisphosphatases for full virulence in laboratory models.

artículo científico publicado en 2014

Brucella melitensis 16M produces a mannan and other extracellular matrix components typical of a biofilm

artículo científico publicado en 2010

Brucella melitensis MucR, an orthologue of Sinorhizobium meliloti MucR, is involved in resistance to oxidative, detergent, and saline stresses and cell envelope modifications.

artículo científico publicado en 2012

Brucella melitensis invades murine erythrocytes during infection

artículo científico publicado en 2014

Brucella pathogenesis, genes identified from random large-scale screens

artículo científico publicado en 2004

Brucella, nitrogen and virulence.

artículo científico publicado en 2014

Brucellosis at the animal/ecosystem/human interface at the beginning of the 21st century.

scientific article published on 14 May 2011

Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export

artículo científico publicado en 2008

BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions

artículo científico publicado en 2013

Chronic Brucella Infection Induces Selective and Persistent Interferon Gamma-Dependent Alterations of Marginal Zone Macrophages in the Spleen.

artículo científico publicado en 2017

Cloning and sequence analysis of a newly identified Brucella abortus gene and serological evaluation of the 17-kilodalton antigen that it encodes ⬇️

artículo científico publicado el 1 de mayo de 1995

Comparison between ‘IgY technology’ from chickens and ‘IgG technology’ from mice for production of tailor-made antibodies

Convergent evolution of zoonotic Brucella species toward the selective use of the pentose phosphate pathway

artículo científico publicado en 2020

Correlations between carbon metabolism and virulence in bacteria

scientific article published on 02 June 2009

Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice

artículo científico publicado en 2012

CtrA controls cell division and outer membrane composition of the pathogen Brucella abortus

artículo científico publicado en 2016

DNA immunization with plasmids encoding fusion and nucleocapsid proteins of bovine respiratory syncytial virus induces a strong cell-mediated immunity and protects calves against challenge.

artículo científico publicado en 2007

DNA polymorphism analysis of Brucella lipopolysaccharide genes reveals marked differences in O-polysaccharide biosynthetic genes between smooth and rough Brucella species and novel species-specific markers

artículo científico publicado en 2009

Design and implementation of a database for Brucella melitensis genome annotation.

artículo científico

Documenting the absence of brucellosis in cattle, goats and dogs in a "One Health" interface in the Mnisi community, Limpopo, South Africa

artículo científico publicado en 2017

Effect of omp10 or omp19 deletion on Brucella abortus outer membrane properties and virulence in mice

artículo científico publicado en 2002

Erythritol Availability in Bovine, Murine and Human Models Highlights a Potential Role for the Host Aldose Reductase during Brucella Infection

artículo científico publicado en 2017

Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella

artículo científico publicado en 2014

Field performance of six Mycobacterium avium subsp. paratuberculosis antigens in a 20h interferon gamma release assay in Belgium

artículo científico publicado en 2017

First synthesis of 3- O -methyl-scyllo-inosamine, a natural product which favors the Rhizobium–Leguminosae symbiosis

From the discovery of the Malta fever's agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis.

artículo científico publicado en 2005

Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen Brucella melitensis

artículo científico publicado en 2010

Functional, molecular and structural characterisation of five anti-Brucella LPS mAb.

artículo científico publicado en 2004

G1-arrested newborn cells are the predominant infectious form of the pathogen Brucella abortus

artículo científico publicado en 2014

Gateway-based destination vectors for functional analyses of bacterial ORFeomes: application to the Min system in Brucella abortus

artículo científico publicado en 2006

Generation of the Brucella melitensis ORFeome version 1.1.

artículo científico publicado en 2004

Global analysis of quorum sensing targets in the intracellular pathogen Brucella melitensis 16 M

artículo científico publicado en 2010

How to substantiate eradication of bovine brucellosis when aspecific serological reactions occur in the course of brucellosis testing.

artículo científico publicado en 2002

Humoral immunity and CD4+ Th1 cells are both necessary for a fully protective immune response upon secondary infection with Brucella melitensis

artículo científico publicado en 2014

Identification of Immune Effectors Essential to the Control of Primary and Secondary Intranasal Infection with Brucella melitensis in Mice.

artículo científico publicado en 2016

Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2.

artículo científico publicado en 2011

Identification of a quorum-sensing signal molecule in the facultative intracellular pathogen Brucella melitensis

artículo científico publicado en 2002

Identification of the essential Brucella melitensis porin Omp2b as a suppressor of Bax-induced cell death in yeast in a genome-wide screening

artículo científico publicado en 2010

Identification of the perosamine synthetase gene of Brucella melitensis 16M and involvement of lipopolysaccharide O side chain in Brucella survival in mice and in macrophages. ⬇️

artículo científico publicado en 1998

Immunogenicity and protective efficacy of DNA vaccines encoding MAP0586c and MAP4308c of Mycobacterium avium subsp. paratuberculosis secretome

article

Immunogenicity of eight Mycobacterium avium subsp. paratuberculosis specific antigens in DNA vaccinated and Map infected mice

artículo científico publicado en 2011

Immunological response of mice to the bovine respiratory syncytial virus fusion glycoprotein expressed in recombinant baculovirus infected insect cells ⬇️

artículo científico publicado el 1 de enero de 1996

In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice

artículo científico publicado en 2015

In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice

artículo científico publicado en 2012

Innate immune recognition of flagellin limits systemic persistence of Brucella

artículo científico publicado en 2013

Mitochondria: a target for bacteria

artículo científico publicado en 2015

Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria.

artículo científico publicado en 2018

Morphological analysis of the sheathed flagellum of Brucella melitensis

artículo científico publicado en 2010

Morphological and functional asymmetry in α-proteobacteria

artículo científico publicado en 2004

Mutations of the quorum sensing-dependent regulator VjbR lead to drastic surface modifications in Brucella melitensis

artículo científico publicado en 2007

MyD88-Dependent Activation of B220-CD11b+LY-6C+ Dendritic Cells during Brucella melitensis Infection

artículo científico publicado en 2007

NnrA is required for full virulence and regulates several Brucella melitensis denitrification genes

artículo científico publicado en 2006

On the link between cell cycle and infection of the Alphaproteobacterium Brucella abortus

artículo científico publicado en 2014

Overproduced Brucella abortus PdhS-mCherry forms soluble aggregates in Escherichia coli, partially associating with mobile foci of IbpA-YFP.

artículo científico publicado en 2010

PdhS, an old-pole-localized histidine kinase, recruits the fumarase FumC in Brucella abortus

artículo científico publicado en 2010

Plasticity of a transcriptional regulation network among alpha-proteobacteria is supported by the identification of CtrA targets in Brucella abortus

artículo científico publicado en 2002

Protective killed Ehrlichia ruminantium vaccine elicits IFN-gamma responses by CD4+ and CD8+ T lymphocytes in goats

artículo científico publicado en 2004

Quorum sensing and self-quorum quenching in the intracellular pathogen Brucellamelitensis

artículo científico publicado en 2013

Replication of Brucella abortus and Brucella melitensis in fibroblasts does not require Atg5-dependent macroautophagy

artículo científico publicado en 2014

Role of FlbT in flagellin production in Brucella melitensis

artículo científico publicado en 2011

Rough mutants defective in core and O-polysaccharide synthesis and export induce antibodies reacting in an indirect ELISA with smooth lipopolysaccharide and are less effective than Rev 1 vaccine against Brucella melitensis infection of sheep.

artículo científico publicado en 2009

Route of Infection Strongly Impacts the Host-Pathogen Relationship

artículo científico publicado en 2019

RpoE1, an extracytoplasmic function sigma factor, is a repressor of the flagellar system in Brucella melitensis

scientific article published on 27 January 2011

Small GTPases andBrucellaentry into the endoplasmic reticulum

artículo científico publicado en 2012

Streptococcal products and leukocyte activities ⬇️

artículo científico publicado el 15 de febrero de 1992

Structural analysis of Brucella abortus RicA substitutions that do not impair interaction with human Rab2 GTPase

artículo científico publicado en 2012

Systematic targeted mutagenesis of Brucella melitensis 16M reveals a major role for GntR regulators in the control of virulence

artículo científico publicado en 2005

The Brucella pathogens are polarized bacteria

artículo científico

The Fast-Growing Brucella suis Biovar 5 Depends on Phosphoenolpyruvate Carboxykinase and Pyruvate Phosphate Dikinase but Not on Fbp and GlpX Fructose-1,6-Bisphosphatases or Isocitrate Lyase for Full Virulence in Laboratory Models.

artículo científico publicado en 2018

The Omp85 protein of Neisseria meningitidis is required for lipid export to the outer membrane

artículo científico publicado en 2003

The Ton system, an ABC transporter, and a universally conserved GTPase are involved in iron utilization by Brucella melitensis 16M.

artículo científico publicado en 2004

The alkylation response protein AidB is localized at the new poles and constriction sites in Brucella abortus

artículo científico publicado en 2011

The asymmetric distribution of the essential histidine kinase PdhS indicates a differentiation event in Brucella abortus

artículo científico publicado en 2007

The genome sequence of the facultative intracellular pathogen Brucella melitensis

artículo científico publicado en 2001

The histidine kinase PdhS controls cell cycle progression of the pathogenic alphaproteobacterium Brucella abortus

artículo científico publicado en 2012

The stringent response mediator Rsh is required for Brucella melitensis and Brucella suis virulence, and for expression of the type IV secretion system virB

article

The two-component system PrlS/PrlR of Brucella melitensis is required for persistence in mice and appears to respond to ionic strength.

artículo científico publicado en 2012

Transposon Sequencing of Brucella abortus Uncovers Essential Genes for Growth In Vitro and Inside Macrophages

artículo científico publicado en 2018

Trypanosoma Infection Favors Brucella Elimination via IL-12/IFNγ-Dependent Pathways.

artículo científico publicado en 2017

Vaccination of calves using the BRSV nucleocapsid protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects the lungs against BRSV replication and pathology

scientific article published on 21 July 2008

Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection

artículo científico publicado en 2017

Yersinia enterocolitica as a vehicle for a naked DNA vaccine encoding Brucella abortus bacterioferritin or P39 antigen

artículo científico publicado en 2002

Lista de obras de Jean-Jacques Letesson

3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum.

A Brucella abortus cstA mutant is defective for association with endoplasmic reticulum exit sites and displays altered trafficking in HeLa cells

A quorum-sensing regulator controls expression of both the type IV secretion system and the flagellar apparatus of Brucella melitensis

Allergic Asthma Favors Growth in the Lungs of Infected Mice

An RpoH-like heat shock sigma factor is involved in stress response and virulence in Brucella melitensis 16M

Analysis of the antigen-specific IFN-γ producing T-cell subsets in cattle experimentally infected with Mycobacterium bovis

Brucella Genital Tropism: What's on the Menu

Brucella abortus Cell Cycle and Infection Are Coordinated

Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains

Brucella abortus depends on pyruvate phosphate dikinase and malic enzyme but not on Fbp and GlpX fructose-1,6-bisphosphatases for full virulence in laboratory models.

Brucella melitensis 16M produces a mannan and other extracellular matrix components typical of a biofilm

Brucella melitensis MucR, an orthologue of Sinorhizobium meliloti MucR, is involved in resistance to oxidative, detergent, and saline stresses and cell envelope modifications.

Brucella melitensis invades murine erythrocytes during infection

Brucella pathogenesis, genes identified from random large-scale screens

Brucella, nitrogen and virulence.

Brucellosis at the animal/ecosystem/human interface at the beginning of the 21st century.

Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export

BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions

Chronic Brucella Infection Induces Selective and Persistent Interferon Gamma-Dependent Alterations of Marginal Zone Macrophages in the Spleen.

Cloning and sequence analysis of a newly identified Brucella abortus gene and serological evaluation of the 17-kilodalton antigen that it encodes ⬇️

Comparison between ‘IgY technology’ from chickens and ‘IgG technology’ from mice for production of tailor-made antibodies

Convergent evolution of zoonotic Brucella species toward the selective use of the pentose phosphate pathway

Correlations between carbon metabolism and virulence in bacteria

Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice

CtrA controls cell division and outer membrane composition of the pathogen Brucella abortus

DNA immunization with plasmids encoding fusion and nucleocapsid proteins of bovine respiratory syncytial virus induces a strong cell-mediated immunity and protects calves against challenge.

DNA polymorphism analysis of Brucella lipopolysaccharide genes reveals marked differences in O-polysaccharide biosynthetic genes between smooth and rough Brucella species and novel species-specific markers

Design and implementation of a database for Brucella melitensis genome annotation.

Documenting the absence of brucellosis in cattle, goats and dogs in a "One Health" interface in the Mnisi community, Limpopo, South Africa

Effect of omp10 or omp19 deletion on Brucella abortus outer membrane properties and virulence in mice

Erythritol Availability in Bovine, Murine and Human Models Highlights a Potential Role for the Host Aldose Reductase during Brucella Infection

Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella

Field performance of six Mycobacterium avium subsp. paratuberculosis antigens in a 20h interferon gamma release assay in Belgium

First synthesis of 3- O -methyl-scyllo-inosamine, a natural product which favors the Rhizobium–Leguminosae symbiosis

From the discovery of the Malta fever's agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis.

Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen Brucella melitensis

Functional, molecular and structural characterisation of five anti-Brucella LPS mAb.

G1-arrested newborn cells are the predominant infectious form of the pathogen Brucella abortus

Gateway-based destination vectors for functional analyses of bacterial ORFeomes: application to the Min system in Brucella abortus

Generation of the Brucella melitensis ORFeome version 1.1.

Global analysis of quorum sensing targets in the intracellular pathogen Brucella melitensis 16 M

How to substantiate eradication of bovine brucellosis when aspecific serological reactions occur in the course of brucellosis testing.

Humoral immunity and CD4+ Th1 cells are both necessary for a fully protective immune response upon secondary infection with Brucella melitensis

Identification of Immune Effectors Essential to the Control of Primary and Secondary Intranasal Infection with Brucella melitensis in Mice.

Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2.

Identification of a quorum-sensing signal molecule in the facultative intracellular pathogen Brucella melitensis

Identification of the essential Brucella melitensis porin Omp2b as a suppressor of Bax-induced cell death in yeast in a genome-wide screening

Identification of the perosamine synthetase gene of Brucella melitensis 16M and involvement of lipopolysaccharide O side chain in Brucella survival in mice and in macrophages. ⬇️

Immunogenicity and protective efficacy of DNA vaccines encoding MAP0586c and MAP4308c of Mycobacterium avium subsp. paratuberculosis secretome

Immunogenicity of eight Mycobacterium avium subsp. paratuberculosis specific antigens in DNA vaccinated and Map infected mice

Immunological response of mice to the bovine respiratory syncytial virus fusion glycoprotein expressed in recombinant baculovirus infected insect cells ⬇️

In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice

In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice

Innate immune recognition of flagellin limits systemic persistence of Brucella

Mitochondria: a target for bacteria

Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria.

Morphological analysis of the sheathed flagellum of Brucella melitensis

Morphological and functional asymmetry in α-proteobacteria

Mutations of the quorum sensing-dependent regulator VjbR lead to drastic surface modifications in Brucella melitensis

MyD88-Dependent Activation of B220-CD11b+LY-6C+ Dendritic Cells during Brucella melitensis Infection

NnrA is required for full virulence and regulates several Brucella melitensis denitrification genes

On the link between cell cycle and infection of the Alphaproteobacterium Brucella abortus

Overproduced Brucella abortus PdhS-mCherry forms soluble aggregates in Escherichia coli, partially associating with mobile foci of IbpA-YFP.

PdhS, an old-pole-localized histidine kinase, recruits the fumarase FumC in Brucella abortus

Plasticity of a transcriptional regulation network among alpha-proteobacteria is supported by the identification of CtrA targets in Brucella abortus

Protective killed Ehrlichia ruminantium vaccine elicits IFN-gamma responses by CD4+ and CD8+ T lymphocytes in goats

Quorum sensing and self-quorum quenching in the intracellular pathogen Brucellamelitensis

Replication of Brucella abortus and Brucella melitensis in fibroblasts does not require Atg5-dependent macroautophagy

Role of FlbT in flagellin production in Brucella melitensis

Rough mutants defective in core and O-polysaccharide synthesis and export induce antibodies reacting in an indirect ELISA with smooth lipopolysaccharide and are less effective than Rev 1 vaccine against Brucella melitensis infection of sheep.

Route of Infection Strongly Impacts the Host-Pathogen Relationship

RpoE1, an extracytoplasmic function sigma factor, is a repressor of the flagellar system in Brucella melitensis

Small GTPases andBrucellaentry into the endoplasmic reticulum

Streptococcal products and leukocyte activities ⬇️

Structural analysis of Brucella abortus RicA substitutions that do not impair interaction with human Rab2 GTPase

Systematic targeted mutagenesis of Brucella melitensis 16M reveals a major role for GntR regulators in the control of virulence

The Brucella pathogens are polarized bacteria

The Fast-Growing Brucella suis Biovar 5 Depends on Phosphoenolpyruvate Carboxykinase and Pyruvate Phosphate Dikinase but Not on Fbp and GlpX Fructose-1,6-Bisphosphatases or Isocitrate Lyase for Full Virulence in Laboratory Models.

The Omp85 protein of Neisseria meningitidis is required for lipid export to the outer membrane