Lista de obras - Tony Ng - Dominio Público Uruguay

3D super-resolution imaging with blinking quantum dots

artículo científico publicado en 2013

A Phase III Study of Recombinant Human Interferon Gamma to Prevent Opportunistic Infections in Advanced HIV Disease

article

A cellular assay using metal-modified fluorescence lifetime analysis for high-content screening of protein internalization

A cellular screening assay using analysis of metal-modified fluorescence lifetime

artículo científico publicado en 2010

A dark yellow fluorescent protein (YFP)-based Resonance Energy-Accepting Chromoprotein (REACh) for Förster resonance energy transfer with GFP.

artículo científico publicado en 2006

A facile route to CdTe nanoparticles and their use in bio-labelling

A high speed multifocal multiphoton fluorescence lifetime imaging microscope for live-cell FRET imaging

artículo científico publicado en 2015

A high-content screening platform utilizing polarization anisotropy and FLIM microscopy

A multi-functional imaging approach to high-content protein interaction screening ⬇️

artículo científico publicado en 2012

A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility

artículo científico publicado en 2002

A role for the pseudokinase HER3 in the acquired resistance against EGFR- and HER2-directed targeted therapy

artículo científico publicado en 2014

A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse

artículo científico publicado en 2011

A whole-body dual-modality radionuclide optical strategy for preclinical imaging of metastasis and heterogeneous treatment response in different microenvironments.

artículo científico publicado en 2014

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

artículo científico publicado en 2018

Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42

artículo científico publicado en 2007

Adhesion co-receptor expression and intracellular signalling in HIV disease: implications for immunotherapy

article

An active Src kinase-beta-actin association is linked to actin dynamics at the periphery of colon cancer cells

artículo científico publicado en 2007

An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis

artículo científico publicado en 2009

Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer

artículo científico publicado en 2014

Apoptin interacts with and regulates the activity of protein kinase C beta in cancer cells

artículo científico publicado en 2015

Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma

artículo científico publicado en 2017

Associations of C-Reactive Protein, Granulocytes and Granulocyte-to-Lymphocyte Ratio with Mortality from Breast Cancer in Non-Institutionalized American Women

artículo científico publicado en 2016

BRCA1 mutations and luminal-basal transformation

artículo científico publicado en 2012

Breast cancer-associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells

artículo científico publicado en 2020

C2c: turning cancer into chronic disease

scientific article (publication date: 2014)

Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration

artículo científico publicado en 2010

Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment

artículo científico publicado en 2016

DART: Denoising Algorithm based on Relevance network Topology improves molecular pathway activity inference

artículo científico publicado en 2011

DESENSITIZATION OF THE INFLAMMATORY RESPONSE IN HUMANS

artículo científico publicado en 1997

Deep-tissue multiphoton fluorescence lifetime microscopy for intravital imaging of protein-protein interactions

article published in 2009

Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice.

artículo científico publicado en 2015

Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor

artículo científico publicado en 2017

Differential activation of the PI 3-kinase effectors AKT/PKB and p70 S6 kinase by compound 48/80 is mediated by PKCalpha

artículo científico publicado en 2006

Direct Response Analysis in cellular signalling networks

artículo científico publicado en 2012

Effect of phosphorylation on EGFR dimer stability probed by single-molecule dynamics and FRET/FLIM.

artículo científico publicado en 2015

Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility

artículo científico publicado en 2001

Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells

artículo científico publicado en 2016

Fluorescence axial nanotomography with plasmonics

artículo científico publicado en 2015

Fluorescence lifetime endoscopy using TCSPC for the measurement of FRET in live cells

artículo científico publicado en 2010

From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-alpha kinase activity

artículo científico publicado en 2009

Functional implications of assigned, assumed and assembled PKC structures

artículo científico publicado en 2014

Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study

artículo científico publicado en 2017

HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status

scientific article published on 13 July 2016

How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology

artículo científico publicado en 2011

INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted magnetic resonance imaging for the prediction and characterization of prostate cancer

artículo científico publicado en 2016

Imaging proteins in vivo using fluorescence lifetime microscopy

artículo científico publicado en 2007

Imaging tumour heterogeneity of the consequences of a PKCα-substrate interaction in breast cancer patients

artículo científico publicado en 2014

In Vivo Imaging of Pro- and Antitumoral Cellular Components of the Tumor Microenvironment

artículo científico publicado en 2017

Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.

artículo científico publicado en 2018

Integrating receptor signal inputs that influence small Rho GTPase activation dynamics at the immunological synapse

artículo científico publicado en 2009

Integrin signalling defects in T-lymphocytes in systemic lupus erythematosus

scientific article published on 01 January 1999

Integrin-protein kinase C relationships

artículo científico publicado en 2003

Integrin-specific signaling pathways controlling focal adhesion formation and cell migration.

artículo científico publicado en 2003

Interaction of fascin and protein kinase Calpha: a novel intersection in cell adhesion and motility

artículo científico publicado en 2003

Intracellular coupling of adhesion receptors: molecular proximity measurements

artículo científico publicado en 2002

Intraperitoneal rituximab: an effective measure to control recurrent abdominal ascites due to non-Hodgkin's lymphoma.

artículo científico publicado en 2002

Investigating the association between allergen-specific immunoglobulin E, cancer risk and survival

artículo científico publicado en 2016

Kinase-mediated quasi-dimers of EGFR

artículo científico publicado en 2010

LESSON OF THE MONTH – Catastrophic Arterial Thromboembolism Associated with Factor V Leiden

scientific article published on 01 May 2000

Lipid chain geometry of C14 glycerol-based lipids: effect on lipoplex structure and transfection

artículo científico publicado en 2010

Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons

artículo científico publicado en 2001

Lipopolyplex ternary delivery systems incorporating C14 glycerol-based lipids

artículo científico publicado en 2011

MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition

artículo científico publicado en 2017

Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis

artículo científico publicado en 2018

Memory effects in biochemical networks as the natural counterpart of extrinsic noise

artículo científico publicado en 2014

Multifocal multiphoton microscopy with adaptive optical correction

article

Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions

artículo científico publicado en 2004

NMR metabolomics of MTLn3E breast cancer cells identifies a role for CXCR4 in lipid and choline regulation.

artículo científico publicado en 2012

Non-Caseating Granulomata Associated with Hypocellular Myelodysplastic Syndrome

artículo científico publicado en 2000

Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans

artículo científico publicado en 2022

PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic

artículo científico publicado en 1999

Plasmon-Assisted Super-Resolution Axial Distance Sensitivity in Fluorescence Cell Imaging

Precision medicine for prostate cancer

artículo científico publicado en 2014

Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1, and Akt

artículo científico publicado en 2010

Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution Microscopy

artículo científico publicado en 2016

Profiling the immune stromal interface in breast cancer and its potential for clinical impact

artículo científico publicado en 2012

Quantification of HER family receptors in breast cancer

artículo científico publicado en 2015

RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers

artículo científico publicado en 2017

Radiation therapy and the innate immune response: clinical implications for immunotherapy approaches

artículo científico publicado en 2020

Regulation of protein tyrosine phosphatase 1B by sumoylation

artículo científico publicado en 2007

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets

artículo científico publicado en 2011

Scanning total internal reflection fluorescence imaging

article

Serum lactate dehydrogenase and survival following cancer diagnosis

artículo científico publicado en 2015

Serum leptin, C-reactive protein, and cancer mortality in the NHANES III

artículo científico publicado en 2015

Silencing of EphA3 through a cis interaction with ephrinA5.

artículo científico publicado en 2006

Single molecule FRET using the FRET pair DRONPA/PhotoActivable mCherry

Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis.

artículo científico publicado en 2002

Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells

artículo científico publicado en 2005

Stabilized integrin-targeting ternary LPD (lipopolyplex) vectors for gene delivery designed to disassemble within the target cell

artículo científico publicado en 2009

Steady-state acceptor fluorescence anisotropy imaging under evanescent excitation for visualisation of FRET at the plasma membrane

artículo científico publicado en 2014

T Cell Costimulation by Derivatives of Benzoic Acid

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility

artículo científico publicado en 2014

The Gray Institute open microscopes applied to radiobiology and protein interaction studies

scholarly article published 12 March 2014

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

artículo científico publicado en 2009

The challenges of integrating molecular imaging into the optimization of cancer therapy.

artículo científico publicado en 2011

The potential of optical proteomic technologies to individualize prognosis and guide rational treatment for cancer patients

artículo científico publicado en 2009

The use of molecular imaging combined with genomic techniques to understand the heterogeneity in cancer metastasis

artículo científico publicado en 2014

Time-correlated single-photon counting fluorescence lifetime confocal imaging of decayed and sound dental structures with a white-light supercontinuum source.

artículo científico publicado en 2007

Time-domain microfluidic fluorescence lifetime flow cytometry for high-throughput Förster resonance energy transfer screening

artículo científico publicado en 2014

Time-lapse FRET microscopy using fluorescence anisotropy

artículo científico publicado en 2010

Toward operative in vivo fluorescence imaging of the c-Met proto-oncogene for personalization of therapy in ovarian cancer.

artículo científico publicado en 2014

Two-photon 3D FIONA of individual quantum dots in an aqueous environment

artículo científico publicado en 2011

Using adaptive optics for deep in-vivo multiphoton FLIM

Visualisation of signalling in immune cells

artículo científico publicado en 2010

Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment

artículo científico publicado en 2017

[18F]tetrafluoroborate-PET/CT enables sensitive tumor and metastasis in vivo imaging in a sodium iodide symporter-expressing tumor model

artículo científico publicado en 2017

c-Met PET Imaging Detects Early-Stage Locoregional Recurrence of Basal-Like Breast Cancer.

artículo científico publicado en 2015

satFRET: estimation of Förster resonance energy transfer by acceptor saturation

artículo científico publicado en 2008

Lista de obras de Tony Ng

3D super-resolution imaging with blinking quantum dots

A Phase III Study of Recombinant Human Interferon Gamma to Prevent Opportunistic Infections in Advanced HIV Disease

A cellular assay using metal-modified fluorescence lifetime analysis for high-content screening of protein internalization

A cellular screening assay using analysis of metal-modified fluorescence lifetime

A dark yellow fluorescent protein (YFP)-based Resonance Energy-Accepting Chromoprotein (REACh) for Förster resonance energy transfer with GFP.

A facile route to CdTe nanoparticles and their use in bio-labelling

A high speed multifocal multiphoton fluorescence lifetime imaging microscope for live-cell FRET imaging

A high-content screening platform utilizing polarization anisotropy and FLIM microscopy

A multi-functional imaging approach to high-content protein interaction screening ⬇️

A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility

A role for the pseudokinase HER3 in the acquired resistance against EGFR- and HER2-directed targeted therapy

A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse

A whole-body dual-modality radionuclide optical strategy for preclinical imaging of metastasis and heterogeneous treatment response in different microenvironments.

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42

Adhesion co-receptor expression and intracellular signalling in HIV disease: implications for immunotherapy

An active Src kinase-beta-actin association is linked to actin dynamics at the periphery of colon cancer cells

An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis

Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer

Apoptin interacts with and regulates the activity of protein kinase C beta in cancer cells

Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma

Associations of C-Reactive Protein, Granulocytes and Granulocyte-to-Lymphocyte Ratio with Mortality from Breast Cancer in Non-Institutionalized American Women

BRCA1 mutations and luminal-basal transformation

Breast cancer-associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells

C2c: turning cancer into chronic disease

Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration

Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment

DART: Denoising Algorithm based on Relevance network Topology improves molecular pathway activity inference

DESENSITIZATION OF THE INFLAMMATORY RESPONSE IN HUMANS

Deep-tissue multiphoton fluorescence lifetime microscopy for intravital imaging of protein-protein interactions

Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice.

Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor

Differential activation of the PI 3-kinase effectors AKT/PKB and p70 S6 kinase by compound 48/80 is mediated by PKCalpha

Direct Response Analysis in cellular signalling networks

Effect of phosphorylation on EGFR dimer stability probed by single-molecule dynamics and FRET/FLIM.

Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility

Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells

Fluorescence axial nanotomography with plasmonics

Fluorescence lifetime endoscopy using TCSPC for the measurement of FRET in live cells

From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-alpha kinase activity

Functional implications of assigned, assumed and assembled PKC structures

Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study

HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status

How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology

INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted magnetic resonance imaging for the prediction and characterization of prostate cancer

Imaging proteins in vivo using fluorescence lifetime microscopy

Imaging tumour heterogeneity of the consequences of a PKCα-substrate interaction in breast cancer patients

In Vivo Imaging of Pro- and Antitumoral Cellular Components of the Tumor Microenvironment

Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.

Integrating receptor signal inputs that influence small Rho GTPase activation dynamics at the immunological synapse

Integrin signalling defects in T-lymphocytes in systemic lupus erythematosus

Integrin-protein kinase C relationships

Integrin-specific signaling pathways controlling focal adhesion formation and cell migration.

Interaction of fascin and protein kinase Calpha: a novel intersection in cell adhesion and motility

Intracellular coupling of adhesion receptors: molecular proximity measurements

Intraperitoneal rituximab: an effective measure to control recurrent abdominal ascites due to non-Hodgkin's lymphoma.

Investigating the association between allergen-specific immunoglobulin E, cancer risk and survival

Kinase-mediated quasi-dimers of EGFR

LESSON OF THE MONTH – Catastrophic Arterial Thromboembolism Associated with Factor V Leiden

Lipid chain geometry of C14 glycerol-based lipids: effect on lipoplex structure and transfection

Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons

Lipopolyplex ternary delivery systems incorporating C14 glycerol-based lipids

MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition

Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis

Memory effects in biochemical networks as the natural counterpart of extrinsic noise

Multifocal multiphoton microscopy with adaptive optical correction

Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions

NMR metabolomics of MTLn3E breast cancer cells identifies a role for CXCR4 in lipid and choline regulation.

Non-Caseating Granulomata Associated with Hypocellular Myelodysplastic Syndrome

Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans

PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic

Plasmon-Assisted Super-Resolution Axial Distance Sensitivity in Fluorescence Cell Imaging

Precision medicine for prostate cancer

Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1, and Akt

Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution Microscopy

Profiling the immune stromal interface in breast cancer and its potential for clinical impact

Quantification of HER family receptors in breast cancer

RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers

Radiation therapy and the innate immune response: clinical implications for immunotherapy approaches