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Lista de obras de Marc Diederich

2,5-Dimethyl-celecoxib inhibits cell cycle progression and induces apoptosis in human leukemia cells

artículo científico publicado en 2015

4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer

artículo científico publicado en 2015

4α-Methylated steroids with cytotoxic activity from the soft coral Litophyton mollis

artículo científico publicado en 2016

5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia

artículo científico publicado en 2014

A LIM domain protein from tobacco involved in actin-bundling and histone gene transcription.

artículo científico publicado en 2012

A Survey of Marine Natural Compounds and Their Derivatives with Anti-cancer Activity Reported in 2012.

artículo científico

A beginner's guide to NF-kappaB signaling pathways

artículo científico publicado en 2004

A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death.

artículo científico publicado en 2013

A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2010.

artículo científico publicado en 2011

A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2011.

artículo científico publicado en 2013

About canonical, non-canonical and immunogenic cell death: Basic mechanisms and translational applications: A meeting report of the International Cell Death Society

artículo científico publicado en 2018

An introduction to the molecular mechanisms of apoptosis

artículo científico publicado en 2003

Anemia in cancer

artículo científico publicado en 2010

Antagonistic role of natural compounds in mTOR-mediated metabolic reprogramming

artículo científico publicado en 2014

Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways.

artículo científico publicado en 2017

Anti-inflammatory and anticancer drugs from nature

artículo científico

Anti-inflammatory, pro-apoptotic, and anti-proliferative effects of a methanolic neem (Azadirachta indica) leaf extract are mediated via modulation of the nuclear factor-κB pathway.

artículo científico publicado en 2010

Anti-proliferative potential of curcumin in androgen-dependent prostate cancer cells occurs through modulation of the Wingless signaling pathway

artículo científico publicado en 2011

Anti-proliferative, Cytotoxic and NF-ĸB Inhibitory Properties of Spiro(Lactone-Cyclohexanone) Compounds in Human Leukemia

artículo científico publicado en 2017

Anticancer and Immunogenic Properties of Cardiac Glycosides

artículo científico publicado en 2017

Anticancer bioactivity of compounds from medicinal plants used in European medieval traditions.

artículo científico publicado en 2013

Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity

artículo científico publicado en 2013

Anticancer potential of naturally occurring immunoepigenetic modulators: A promising avenue?

scientific article published on 06 March 2019

Antioxidant and anti-proliferative properties of lycopene

artículo científico publicado en 2011

Antiproliferative and proapoptotic activities of 4-hydroxybenzoic acid-based inhibitors of histone deacetylases

artículo científico publicado en 2013

Antiproliferative effect of natural tetrasulfides in human breast cancer cells is mediated through the inhibition of the cell division cycle 25 phosphatases

artículo científico publicado en 2011

Assembling the puzzle of anti-cancer mechanisms triggered by cardiac glycosides

artículo científico publicado en 2012

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

artículo científico publicado en 2018

Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic cardiac glycoside UNBS1450 in acute myeloid leukemia.

artículo científico publicado en 2016

Bioactive Bromotyrosine Derivatives from the Pacific Marine Sponge <i>Suberea clavata</i> (Pulitzer-Finali, 1982)

artículo científico

Bioactive diterpene derivatives from the marine sponge Spongionella sp.

artículo científico publicado en 2009

Biotinylation enhances the anticancer effects of 15d‑PGJ2 against breast cancer cells.

artículo científico publicado en 2018

Bis(4-hydroxy-2H-chromen-2-one): synthesis and effects on leukemic cell lines proliferation and NF-κB regulation.

artículo científico publicado en 2014

Breakthrough in tracking tumor erythropoietin receptor expression

artículo científico publicado en 2012

COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells

artículo científico publicado en 2011

Cancer-type-specific crosstalk between autophagy, necroptosis and apoptosis as a pharmacological target

artículo científico publicado en 2015

Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.

artículo científico publicado en 2018

Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials.

artículo científico publicado en 2013

Cardiac glycosides: From molecular targets to immunogenic cell death.

artículo científico publicado en 2016

Celecoxib prevents curcumin-induced apoptosis in a hematopoietic cancer cell model.

artículo científico publicado en 2014

Cell cycle arrest in early mitosis and induction of caspase-dependent apoptosis in U937 cells by diallyltetrasulfide (Al2S4).

artículo científico publicado en 2009

Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma.

artículo científico publicado en 2015

Chemopreventive and therapeutic effects of curcumin

artículo científico publicado en 2004

Chemopreventive potential of curcumin in prostate cancer

artículo científico publicado en 2009

Chromatin-modifying agents in anti-cancer therapy

artículo científico

Coffee provides a natural multitarget pharmacopeia against the hallmarks of cancer

artículo científico publicado en 2015

Conference Scene: Omic Technologies in Human Disease: Extending the Network of Epigenetic Control ⬇️

artículo científico publicado el 1 de octubre de 2011

Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells.

artículo científico publicado en 2011

Curcumin as a regulator of epigenetic events

artículo científico publicado en 2013

Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells

artículo científico publicado en 2006

Curcumin stability and its effect on glutathione S-transferase P1-1 mRNA expression in K562 cells

artículo científico publicado en 2004

Curcumin-induced cell death in two leukemia cell lines: K562 and Jurkat

artículo científico publicado en 2003

Curcumin―The Paradigm of a Multi-Target Natural Compound with Applications in Cancer Prevention and Treatment ⬇️

artículo científico publicado el 21 de enero de 2010

Cytostatic hydroxycoumarin OT52 induces ER/Golgi stress and STAT3 inhibition triggering non-canonical cell death and synergy with BH3 mimetics in lung cancer.

artículo científico publicado en 2017

Cytotoxic, Antiproliferative and Pro-Apoptotic Effects of 5-Hydroxyl-6,7,3',4',5'-Pentamethoxyflavone Isolated from Lantana ukambensis

artículo científico publicado en 2015

DNA damage response: the emerging role of c-Abl as a regulatory switch?

artículo científico publicado en 2011

DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs

artículo científico publicado en 2012

Decrypting the labyrinth of inflammatory cell signaling pathways: Editorial to the meeting "Inflammation 2010".

artículo científico publicado en 2010

Dermacozines, a new phenazine family from deep-sea dermacocci isolated from a Mariana Trench sediment.

artículo científico publicado en 2010

Development of a matrix-assisted laser desorption/ionization-mass spectrometry screening test to evidence reversible and irreversible inhibitors of CDC25 phosphatases

artículo científico publicado en 2012

Diallylpolysulfides induce growth arrest and apoptosis.

artículo científico publicado en 2010

Dietary chalcones with chemopreventive and chemotherapeutic potential

artículo científico publicado en 2011

Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory network

artículo científico publicado en 2012

Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.

artículo científico publicado en 2017

Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells

artículo científico publicado en 2016

Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450

artículo científico publicado en 2015

Editorial: Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis

artículo científico publicado en 2019

Effect of chemopreventive agents on glutathione S-transferase P1-1 gene expression mechanisms via activating protein 1 and nuclear factor kappaB inhibition

artículo científico publicado en 2004

Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells

artículo científico publicado en 2009

Effect of curcumin treatment on protein phosphorylation in K562 cells

artículo científico publicado en 2007

Effects of Natural Products on Mcl-1 Expression and Function

artículo científico

Embellicines A and B: Absolute Configuration and NF-κB Transcriptional Inhibitory Activity

artículo científico publicado en 2013

Energy restriction mimetic agents to target cancer cells: comparison between 2-deoxyglucose and thiazolidinediones.

artículo científico

Epigenetic alterations as a universal feature of cancer hallmarks and a promising target for personalized treatments

artículo científico

Epigenetic mechanisms underlying the therapeutic effects of HDAC inhibitors in chronic myeloid leukemia

scientific article published on 07 November 2019

Epigenetic modulators from "The Big Blue": a treasure to fight against cancer

artículo científico

Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells

artículo científico publicado en 2013

Epigenetics Offer New Horizons for Colorectal Cancer Prevention ⬇️

artículo científico publicado el 14 de enero de 2012

Epigenomics of leukemia: from mechanisms to therapeutic applications

artículo científico publicado en 2011

Epipolythiodiketopiperazines from the Marine Derived Fungus Dichotomomyces cejpii with NF-κB Inhibitory Potential ⬇️

artículo científico publicado en 2015

Erythropoietin, erythropoiesis and beyond

artículo científico publicado en 2011

Eurycomanone and eurycomanol from Eurycoma longifolia Jack as regulators of signaling pathways involved in proliferation, cell death and inflammation.

artículo científico publicado en 2014

Expression of glutathione S-transferase P1-1 in differentiating K562: role of GATA-1.

artículo científico publicado en 2003

Expression of glutathione S-transferase P1-1 in leukemic cells is regulated by inducible AP-1 binding

artículo científico publicado en 2004

Flavonoid glycosides from Olax mannii: Structure elucidation and effect on the nuclear factor kappa B pathway

artículo científico publicado en 2015

From nature to bedside: pro-survival and cell death mechanisms as therapeutic targets in cancer treatment.

artículo científico publicado en 2014

GTP-mediated differentiation of the human K562 cell line: transient overexpression of GATA-1 and stabilization of the gamma-globin mRNA.

artículo científico publicado en 2000

Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. Evidence for a ubiquitous gamma-glutamyltransferase polypeptide in human tissues

artículo científico publicado en 1992

Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?

artículo científico publicado en 2016

Gene expression profiling related to anti-inflammatory properties of curcumin in K562 leukemia cells

artículo científico publicado en 2009

Gold from the sea: marine compounds as inhibitors of the hallmarks of cancer

scientific article published on March 2011

Goniolandrene A and B from Goniothalamus macrophyllus

artículo científico publicado en 2013

HDAC6-an Emerging Target Against Chronic Myeloid Leukemia?

artículo científico publicado en 2020

Heteronemin, a spongean sesterterpene, inhibits TNF alpha-induced NF-kappa B activation through proteasome inhibition and induces apoptotic cell death

artículo científico publicado en 2010

Histone deacetylase 6 in health and disease

artículo científico publicado en 2015

Histone deacetylase modulators provided by Mother Nature

artículo científico publicado en 2012

Human telomerase reverse transcriptase depletion potentiates the growth-inhibitory activity of imatinib in chronic myeloid leukemia stem cells

scientific article published on 14 November 2019

Hybrid curcumin compounds: a new strategy for cancer treatment.

artículo científico publicado en 2014

Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release

scientific article published on 08 September 2018

Identification and re-addressing of a transcriptionally permissive locus in the porcine genome

artículo científico publicado en 2015

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

scientific article published on 06 May 2019

Identification of differentially expressed proteins in curcumin-treated prostate cancer cell lines

artículo científico publicado en 2012

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

artículo científico publicado en 2013

Increased glutathione S-transferase P1-1 expression by mRNA stabilization in hemin-induced differentiation of K562 cells

artículo científico publicado en 2004

Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition

artículo científico publicado en 2003

Induction of heat shock response by curcumin in human leukemia cells

artículo científico publicado en 2009

Inflammation: novel arrows for an ancient target

artículo científico publicado en 2010

Inhibition of TNFalpha-induced activation of nuclear factor kappaB by kava (Piper methysticum) derivatives

artículo científico publicado en 2006

Inhibitory effect of St. John׳s Wort oil macerates on TNFα-induced NF-κB activation and their fatty acid composition

artículo científico publicado en 2014

Integrated cellular pathology--systems biology of human diseases

scientific article published on 16 June 2011

Integrated cellular pathology-systems biology of human diseases

artículo científico publicado en 2012

Intracellular prooxidant activity of melatonin induces a survival pathway involving NF-kappaB activation.

artículo científico publicado en 2009

Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics

scientific article published on 06 January 2019

Kinase-independent inhibition of cyclophosphamide-induced pathways protects the ovarian reserve and prolongs fertility

scientific article published on 27 September 2019

Linking anemia to inflammation and cancer: the crucial role of TNFalpha

artículo científico publicado en 2009

Live longer, drink (poly)phenols!

artículo científico publicado en 2012

Localization of a regulatory region on the 5'-untranslated region of human hepatoma HepG2 gamma-glutamyltransferase mRNA and response to dexamethasone and antisense oligonucleotide treatment

artículo científico publicado en 1994

Long and short non-coding RNAs as regulators of hematopoietic differentiation

artículo científico publicado en 2013

Long live the cell death!

artículo científico publicado en 2008

Magnetic fields promote a pro-survival non-capacitative Ca2+ entry via phospholipase C signaling

artículo científico publicado en 2010

Marine natural products as targeted modulators of the transcription factor NF-kappaB.

artículo científico publicado en 2007

Marine natural products targeting phospholipases A2.

artículo científico publicado en 2010

Melatonin antagonizes the intrinsic pathway of apoptosis via mitochondrial targeting of Bcl-2.

artículo científico publicado en 2008

Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid

artículo científico publicado en 2015

Melatonin: a pleiotropic molecule regulating inflammation

artículo científico publicado en 2010

Metabolism 2014--alterations of metabolic pathways as therapeutic targets

artículo científico publicado en 2014

Metabolism and cancer: old and new players

artículo científico publicado en 2013

Metabolomic Tools to Assess the Chemistry and Bioactivity of Endophytic Aspergillus Strain

artículo científico publicado en 2017

Methylenedioxy flavonoids: assessment of cytotoxic and anti-cancer potential in human leukemia cells.

artículo científico publicado en 2014

MicroRNAs in cancer management and their modulation by dietary agents

artículo científico

Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells

scientific article published on 03 August 2008

Modulation of poly(ADP-ribosylation) in apoptotic cells

artículo científico publicado en 2004

Modulatory roles of glycolytic enzymes in cell death

artículo científico publicado en 2014

Molecular and therapeutic potential and toxicity of valproic acid

artículo científico publicado en 2010

Multistep and multitask Bax activation

artículo científico publicado en 2010

NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorum.

artículo científico publicado en 2010

NF-κB-Inhibiting Naphthopyrones from the Fijian EchinodermComanthus parvicirrus

article

Natural Compound Histone Deacetylase Inhibitors (HDACi): Synergy with Inflammatory Signaling Pathway Modulators and Clinical Applications in Cancer

artículo científico publicado en 2016

Natural and Synthetic Flavonoids: Structure-Activity Relationship and Chemotherapeutic Potential for the Treatment of Leukemia

artículo científico

Natural chalcones as dual inhibitors of HDACs and NF-κB.

artículo científico publicado en 2012

Natural compound inducers of immunogenic cell death

artículo científico publicado en 2019

Natural compounds and pharmaceuticals reprogram leukemia cell differentiation pathways

artículo científico

Natural compounds as inflammation inhibitors.

artículo científico publicado en 2011

Natural compounds as regulators of the cancer cell metabolism

artículo científico publicado en 2013

Natural dimers of coumarin, chalcones, and resveratrol and the link between structure and pharmacology

artículo científico publicado en 2019

Natural modulators of the hallmarks of immunogenic cell death

artículo científico publicado en 2019

Natural products target the hallmarks of chronic diseases

artículo científico publicado en 2020

Natural scaffolds in anticancer therapy and precision medicine

scientific article published on 03 May 2018

New nodulopeptins from Nodularia spumigena KAC 66

Non-canonical programmed cell death mechanisms triggered by natural compounds.

artículo científico publicado en 2016

Novel Pharmaceutical Approaches by Natural Compound-Derived Epigenetic Regulators: Epigenetic Readers, Writers and Erasers as Therapeutic Targets

artículo científico publicado en 2016

Novel antibodies against receptors, protein kinase inhibitors, and siRNA, targeting both signal transduction and gene expression, will certainly lead to the therapeutic approaches that will be developed and used in this new century. Preface

scientific article published on 01 August 2009

Novel inhibitors of human histone deacetylases: design, synthesis and bioactivity of 3-alkenoylcoumarines

artículo científico publicado en 2014

Novel job opportunities in cell death!

artículo científico publicado en 2008

OMICS, a multidisciplinary friendship

artículo científico publicado en 2012

Oxidation-dependent maturation and survival of explanted blood monocytes via Bcl-2 up-regulation

artículo científico publicado en 2008

Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?

artículo científico

Oxidative upregulation of Bcl-2 in healthy lymphocytes.

artículo científico publicado en 2006

Oxidative, multistep activation of the noncanonical NF-kappaB pathway via disulfide Bcl-3/p50 complex

artículo científico publicado en 2008

P53 and Sirt1: routes of metabolism and genome stability

artículo científico

PPARγ-inactive Δ2-troglitazone independently triggers ER stress and apoptosis in breast cancer cells

artículo científico publicado en 2013

Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress

artículo científico publicado en 2013

Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)

artículo científico publicado en 2019

Perspectives in Medicinal Chemistry: DNA Methylation and Demethylation Mechanisms as Therapeutic Targets?

artículo científico publicado en 2016

Petromurin C Induces Protective Autophagy and Apoptosis in FLT3-ITD-Positive AML: Synergy with Gilteritinib

artículo científico publicado en 2020

Phorbol ester regulation of the human gamma-glutamyltransferase gene promoter

artículo científico publicado en 2004

Phorbol ester responsiveness of the glutathione S-transferase P1 gene promoter involves an inducible c-jun binding in human K562 leukemia cells

artículo científico publicado en 2001

Plant-derived epigenetic modulators for cancer treatment and prevention

artículo científico

Plumbagin modulates leukemia cell redox status.

artículo científico publicado en 2014

Polyphenol tri-vanillic ester 13c inhibits P-JAK2V617F and Bcr-Abl oncokinase expression in correlation with STAT3/STAT5 inactivation and apoptosis induction in human leukemia cells

artículo científico publicado en 2013

Potential of the dietary antioxidants resveratrol and curcumin in prevention and treatment of hematologic malignancies.

artículo científico publicado en 2010

Power from the garden: plant compounds as inhibitors of the hallmarks of cancer

artículo científico

Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts

scientific article published on 26 June 2018

Pro-apoptotic and immunostimulatory tetrahydroxanthone dimers from the endophytic fungus Phomopsis longicolla.

artículo científico publicado en 2013

Pro-inflammatory cytokine-mediated anemia: regarding molecular mechanisms of erythropoiesis

artículo científico publicado en 2009

Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity

artículo científico publicado en 2014

Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum

artículo científico publicado en 2013

Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation

artículo científico publicado en 2011

ROS-independent JNK activation and multisite phosphorylation of Bcl-2 link diallyl tetrasulfide-induced mitotic arrest to apoptosis.

artículo científico publicado en 2012

Radicicol-mediated inhibition of Bcr-Abl in K562 cells induced p38-MAPK dependent erythroid differentiation and PU.1 down-regulation

artículo científico publicado en 2008

Redox biology of regulated cell death in cancer: A focus on necroptosis and ferroptosis

scientific article published on 10 January 2019

Redox regulation: natural compound as regulators of inflammation signaling

artículo científico publicado en 2012

Regulation of epigenetic traits of the glutathione S-transferase P1 gene: from detoxification toward cancer prevention and diagnosis

artículo científico publicado en 2014

Regulation of glutathione S-transferase P1-1 gene expression by NF-kappaB in tumor necrosis factor alpha-treated K562 leukemia cells

artículo científico publicado en 2004

Regulation of transcription of the glutathione S-transferase P1 gene by methylation of the minimal promoter in human leukemia cells

artículo científico publicado en 2001

Reply to: Cisplatin-induced primordial follicle oocyte killing and loss of fertility are not prevented by imatinib.

artículo científico publicado en 2012

Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines

artículo científico publicado en 2011

Role of Histone Acetylation in Cell Cycle Regulation

artículo científico

Roles of Apoptosis and Cellular Senescence in Cancer and Aging

artículo científico publicado en 2015

Selective antimicrobial activity associated with sulfur nanoparticles.

artículo científico publicado en 2011

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.

artículo científico publicado en 2013

Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells

artículo científico publicado en 2014

Sequential phases of Ca2+ alterations in pre-apoptotic cells.

artículo científico publicado en 2007

Signal Transducers and Activators of Transcription (STAT) Regulatory Networks in Marine Organisms: From Physiological Observations towards Marine Drug Discovery

artículo científico publicado en 2015

Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription.

artículo científico publicado en 2010

Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells ⬇️

artículo científico publicado en 2018

Stress-induced cellular responses in immunogenic cell death: implications for cancer immunotherapy.

artículo científico publicado en 2018

Styryl-lactone goniothalamin inhibits TNF-α-induced NF-κB activation.

artículo científico publicado en 2013

Subapoptogenic oxidative stress strongly increases the activity of the glycolytic key enzyme glyceraldehyde 3-phosphate dehydrogenase.

artículo científico publicado en 2009

Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy

artículo científico publicado en 2010

Synergistic AML Cell Death Induction by Marine Cytotoxin (+)-1(), 6(), 1'(), 6'(), 11(), 17()-Fistularin-3 and Bcl-2 Inhibitor Venetoclax

scientific article published on 19 December 2018

Synthesis and bioactivity of novel amino-pyrazolopyridines

artículo científico publicado en 2014

Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin

artículo científico publicado en 2010

Synthesis and selective anticancer activity of organochalcogen based redox catalysts

artículo científico publicado en 2010

Synthetic polysulfane derivatives induce cell cycle arrest and apoptotic cell death in human hematopoietic cancer cells.

artículo científico publicado en 2013

Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities.

artículo científico publicado en 2015

Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy.

artículo científico publicado en 2010

Targeting the wingless signaling pathway with natural compounds as chemopreventive or chemotherapeutic agents.

artículo científico publicado en 2012

Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia

artículo científico publicado en 2020

The 5' untranslated region of the human γ-glutamyl transferase mRNA contains a tissue-specific active translational enhancer

scientific article published on 01 October 1993

The DNA hypomethylating agent, 5-aza-2'-deoxycytidine, enhances tumor cell invasion through a transcription-dependent modulation of MMP-1 expression in human fibrosarcoma cells.

artículo científico publicado en 2013

The Eighth Central European Conference "Chemistry towards Biology": Snapshot

artículo científico publicado en 2016

The Forty-Sixth Euro Congress on Drug Synthesis and Analysis: Snapshot †.

artículo científico publicado en 2017

The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition

artículo científico publicado en 2018

The aromatic ketone 4'-hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition

artículo científico publicado en 2011

The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer.

artículo científico publicado en 2017

The dual role of calcium as messenger and stressor in cell damage, death, and survival.

artículo científico publicado en 2010

The inhibition of TNF-alpha-induced NF-kappaB activation by marine natural products

artículo científico publicado en 2009

The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies.

artículo científico publicado en 2010

Traditional West African pharmacopeia, plants and derived compounds for cancer therapy

artículo científico

Transcriptional and post-transcriptional regulation of glutathione S-transferase P1 expression during butyric acid-induced differentiation of K562 cells

artículo científico publicado en 2005

Translational role of natural coumarins and their derivatives as anticancer agents

scientific article published on 29 May 2019

Tubulin-binding anticancer polysulfides induce cell death via mitotic arrest and autophagic interference in colorectal cancer.

artículo científico publicado en 2017

Tumor necrosis factor alpha induces gamma-glutamyltransferase expression via nuclear factor-kappaB in cooperation with Sp1.

artículo científico publicado en 2008

Tumor necrosis factor alpha inhibits aclacinomycin A-induced erythroid differentiation of K562 cells via GATA-1.

artículo científico publicado en 2005

Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation

artículo científico publicado en 2008

Tumor necrosis factor α-mediated inhibition of erythropoiesis involves GATA-1/GATA-2 balance impairment and PU.1 over-expression

artículo científico publicado en 2011

UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death ⬇️

scientific article published on 06 February 2009

UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells

artículo científico publicado en 2010

Valproic acid perturbs hematopoietic homeostasis by inhibition of erythroid differentiation and activation of the myelo-monocytic pathway

artículo científico publicado en 2010

Valproic acid regulates erythro-megakaryocytic differentiation through the modulation of transcription factors and microRNA regulatory micro-networks

artículo científico publicado en 2014

Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer

artículo científico publicado en 2013

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

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