Lista de obras - Stephen A. Duncan - Dominio Público Uruguay

A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia.

artículo científico publicado en 2017

A Screen Using iPSC-Derived Hepatocytes Reveals NAD as a Potential Treatment for mtDNA Depletion Syndrome

artículo científico publicado en 2018

A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells

artículo científico publicado en 2012

A small-molecule screen reveals that HSP90β promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover

artículo científico publicado en 2017

A threshold of GATA4 and GATA6 expression is required for cardiovascular development

artículo científico publicado en 2006

ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion

artículo científico publicado en 2017

Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells

artículo científico publicado en 2014

BMPs on the road to hepatogenesis

artículo científico publicado en 2001

Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

article

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart

scientific journal article

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart.

artículo científico publicado en 2008

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart.

artículo científico publicado en 2008

Chromatin remodeling is restricted by transient GATA6 binding during iPSC differentiation to definitive endoderm

artículo científico publicado en 2022

Comparison of cardiomyogenic potential among human ESC and iPSC lines.

artículo científico publicado en 2012

Conserved enhancer in the serum response factor promoter controls expression during early coronary vasculogenesis

artículo científico publicado en 2004

Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum

artículo científico publicado en 2010

Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells

artículo científico publicado en 2015

Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells

artículo científico publicado en 2008

Development of the mammalian liver and ventral pancreas is dependent on GATA4.

artículo científico publicado en 2007

Differentiation of hepatocytes from pluripotent stem cells

artículo científico publicado en 2013

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

scientific journal article

Disruption of the MacMARCKS gene prevents cranial neural tube closure and results in anencephaly

artículo científico publicado en 1996

ER stress controls iron metabolism through induction of hepcidin

artículo científico publicado en 2009

Embryonic development of the liver

artículo científico publicado en 2005

Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice

artículo científico publicado en 2012

Engineering liver tissue from induced pluripotent stem cells: a first step in generating new organs for transplantation?

artículo científico publicado en 2013

Epicardial GATA factors regulate early coronary vascular plexus formation

scientific article published on 28 December 2013

Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development

artículo científico publicado en 2006

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst

artículo científico publicado en 1994

FGF2 mediates hepatic progenitor cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1.

artículo científico publicado en 2015

Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells

artículo científico publicado en 2010

GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice

artículo científico publicado en 2011

GATA4 is essential for formation of the proepicardium and regulates cardiogenesis

scientific journal article

GATA4 is essential for jejunal function in mice

artículo científico publicado en 2008

GATA6 is essential for endoderm formation from human pluripotent stem cells

artículo científico publicado en 2017

Gene targeting in the mouse: advances in introduction of transgenes into the genome by homologous recombination

artículo científico publicado en 2002

Generation of a conditionally null allele ofhnf4?

article

Generation of embryos directly from embryonic stem cells by tetraploid embryo complementation reveals a role for GATA factors in organogenesis

artículo científico publicado en 2005

Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors

artículo científico publicado en 2010

Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells

artículo científico publicado en 2015

Generation of mice harbouring a conditional loss-of-function allele of Gata6.

artículo científico publicado en 2006

Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation

artículo científico publicado en 2001

HNF4: A central regulator of hepatocyte differentiation and function

scientific article published on 01 June 2003

HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human iPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II

article

HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells

artículo científico publicado en 2011

Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice

artículo científico publicado en 2009

Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis

artículo científico publicado en 2003

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon

artículo científico publicado en 2006

Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H

artículo científico publicado en 2008

Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

artículo científico publicado en 2006

Hepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies

artículo científico publicado en 2012

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

artículo científico publicado en 2010

Identification and characterization of an extracellular envelope glycoprotein affecting vaccinia virus egress

artículo científico publicado en 1992

Identification of small molecules for human hepatocyte expansion and iPS differentiation

artículo científico publicado en 2013

Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice

artículo científico publicado en 1999

Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells.

artículo científico publicado en 2006

In situ hybridization with 33P-labeled RNA probes for determination of cellular expression patterns of liver transcription factors in mouse embryos

artículo científico publicado en 1998

Induction of cardiomyogenesis in human embryonic stem cells by human embryonic stem cell-derived definitive endoderm

artículo científico publicado en 2011

Isoflurane preconditioning elicits competent endogenous mechanisms of protection from oxidative stress in cardiomyocytes derived from human embryonic stem cells

artículo científico publicado en 2010

JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia

scientific article published on 17 September 2012

Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells

artículo científico publicado en 2007

Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.

artículo científico publicado en 2017

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci

artículo científico publicado en 2017

Light chain 1 of microtubule-associated protein 1B can negatively regulate the action of Pes1

scientific journal article

Liver Capsule: Multipotent stem cells and their lineage restriction to hepatocytes

artículo científico publicado en 2016

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

artículo científico publicado en 2008

Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.

artículo científico publicado en 2010

Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.

artículo científico publicado en 2000

Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes

artículo científico publicado en 2016

Mechanisms controlling early development of the liver

artículo científico publicado en 2003

Modeling Inborn Errors of Hepatic Metabolism Using Induced Pluripotent Stem Cells

artículo científico publicado en 2017

Modeling hepatitis C virus infection using human induced pluripotent stem cells

artículo científico publicado en 2012

N-glycoprotein surfaceome of human induced pluripotent stem cell derived hepatic endoderm.

artículo científico publicado en 2016

Organogenesis and development of the liver

artículo científico publicado en 2010

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

artículo científico publicado en 2012

Pescadillo is essential for nucleolar assembly, ribosome biogenesis, and mammalian cell proliferation

scientific journal article

Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors

artículo científico publicado en 2004

Protocol for directed differentiation of human pluripotent stem cells toward a hepatocyte fate

artículo científico publicado en 2013

Regulation of a transcription factor network required for differentiation and metabolism

artículo científico publicado en 1998

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis

scientific journal article

Robert H. Costa.

artículo científico publicado en 2006

STAT signaling is active during early mammalian development

artículo científico publicado en 1997

Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner

artículo científico publicado en 2014

The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion

artículo científico publicado en 2005

The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARα and HNF4α in the Liver

artículo científico publicado en 2010

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism ⬇️

artículo científico publicado el 25 de noviembre de 1997

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

artículo científico publicado en 2003

The pancreas and its heartless beginnings

The transcription factor GATA-6 regulates pathological cardiac hypertrophy

scientific journal article

The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism

artículo científico publicado en 2011

The use of human pluripotent stem cells for modelling liver development and disease

article

The vaccinia virus A4OR gene product is a nonstructural, type II membrane glycoprotein that is expressed at the cell surface

artículo científico publicado en 1999

Transcriptional control of hepatocyte differentiation

artículo científico publicado en 2010

Transcriptional regulation of liver development

artículo científico publicado en 2000

Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter

artículo científico publicado en 2006

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery

artículo científico publicado en 2018

Vaccinia DNA ligase complements Saccharomyces cerevisiae cdc9, localizes in cytoplasmic factories and affects virulence and virus sensitivity to DNA damaging agents

artículo científico publicado en 1991

Vaccinia virus gene SalF5R is non-essential for virus replication in vitro and in vivo

artículo científico publicado en 1992

iPSC-Derived Hepatocytes as a Platform for Disease Modeling and Drug Discovery

scientific article published on 15 November 2019

Lista de obras de Stephen A. Duncan

A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia.

A Screen Using iPSC-Derived Hepatocytes Reveals NAD as a Potential Treatment for mtDNA Depletion Syndrome

A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells

A small-molecule screen reveals that HSP90β promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover

A threshold of GATA4 and GATA6 expression is required for cardiovascular development

ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion

Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells

BMPs on the road to hepatogenesis

Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart.

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart.

Chromatin remodeling is restricted by transient GATA6 binding during iPSC differentiation to definitive endoderm

Comparison of cardiomyogenic potential among human ESC and iPSC lines.

Conserved enhancer in the serum response factor promoter controls expression during early coronary vasculogenesis

Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum

Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells

Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells

Development of the mammalian liver and ventral pancreas is dependent on GATA4.

Differentiation of hepatocytes from pluripotent stem cells

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

Disruption of the MacMARCKS gene prevents cranial neural tube closure and results in anencephaly

ER stress controls iron metabolism through induction of hepcidin

Embryonic development of the liver

Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice

Engineering liver tissue from induced pluripotent stem cells: a first step in generating new organs for transplantation?

Epicardial GATA factors regulate early coronary vascular plexus formation

Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst

FGF2 mediates hepatic progenitor cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1.

Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells

GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice

GATA4 is essential for formation of the proepicardium and regulates cardiogenesis

GATA4 is essential for jejunal function in mice

GATA6 is essential for endoderm formation from human pluripotent stem cells

Gene targeting in the mouse: advances in introduction of transgenes into the genome by homologous recombination

Generation of a conditionally null allele ofhnf4?

Generation of embryos directly from embryonic stem cells by tetraploid embryo complementation reveals a role for GATA factors in organogenesis

Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors

Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells

Generation of mice harbouring a conditional loss-of-function allele of Gata6.

Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation

HNF4: A central regulator of hepatocyte differentiation and function

HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human iPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II

HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells

Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice

Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon

Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H

Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

Hepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

Identification and characterization of an extracellular envelope glycoprotein affecting vaccinia virus egress

Identification of small molecules for human hepatocyte expansion and iPS differentiation

Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice

Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells.

In situ hybridization with 33P-labeled RNA probes for determination of cellular expression patterns of liver transcription factors in mouse embryos

Induction of cardiomyogenesis in human embryonic stem cells by human embryonic stem cell-derived definitive endoderm

Isoflurane preconditioning elicits competent endogenous mechanisms of protection from oxidative stress in cardiomyocytes derived from human embryonic stem cells

JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia

Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells

Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci

Light chain 1 of microtubule-associated protein 1B can negatively regulate the action of Pes1

Liver Capsule: Multipotent stem cells and their lineage restriction to hepatocytes

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.

Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.

Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes

Mechanisms controlling early development of the liver

Modeling Inborn Errors of Hepatic Metabolism Using Induced Pluripotent Stem Cells

Modeling hepatitis C virus infection using human induced pluripotent stem cells

N-glycoprotein surfaceome of human induced pluripotent stem cell derived hepatic endoderm.

Organogenesis and development of the liver

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

Pescadillo is essential for nucleolar assembly, ribosome biogenesis, and mammalian cell proliferation

Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors

Protocol for directed differentiation of human pluripotent stem cells toward a hepatocyte fate

Regulation of a transcription factor network required for differentiation and metabolism