Lista de obras - Leigh Murphy - Dominio Público Uruguay

A bi-faceted role of estrogen receptor β in breast cancer

artículo científico publicado en 2013

A framework for biobank sustainability

artículo científico publicado en 2014

A phosphorylation code for oestrogen receptor-alpha predicts clinical outcome to endocrine therapy in breast cancer

artículo científico publicado en 2010

A point mutation in the human estrogen receptor gene is associated with the expression of an abnormal estrogen receptor mRNA containing a 69 novel nucleotide insertion

scientific article published on 01 June 1997

A practical tool for modeling biospecimen user fees

artículo científico publicado en 2014

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

artículo científico publicado en 2014

Altered expression of estrogen receptor-alpha variant messenger RNAs between adjacent normal breast and breast tumor tissues

artículo científico publicado en 2000

Altered expression of exon 6 deleted progesterone receptor variant mRNA between normal human breast and breast tumour tissues

artículo científico publicado en 1999

Analysis of human breast cancer nuclear proteins binding to the promoter elements of the c-myc gene

scientific article published on 01 March 1996

Antiestrogen action and growth factor regulation

artículo científico publicado en 1994

Assay development for the determination of phosphorylation stoichiometry using multiple reaction monitoring methods with and without phosphatase treatment: application to breast cancer signaling pathways

artículo científico publicado en 2010

Assessment of multiple different estrogen receptor-beta antibodies for their ability to immunoprecipitate under chromatin immunoprecipitation conditions

artículo científico publicado en 2006

C-myc gene chromatin of estrogen receptor positive and negative breast cancer cells

scientific article published on 01 February 1993

CARM1 is an important determinant of ERα-dependent breast cancer cell differentiation and proliferation in breast cancer cells

artículo científico publicado en 2011

Certification for biobanks: the program developed by the Canadian Tumour Repository Network (CTRNet).

artículo científico

Claudin 1 expression in basal-like breast cancer is related to patient age

artículo científico publicado en 2013

Claudins 1, 3, and 4 protein expression in ER negative breast cancer correlates with markers of the basal phenotype.

artículo científico publicado en 2009

Clinical significance of estrogen receptor phosphorylation ⬇️

artículo científico publicado el 19 de enero de 2011

Comparative evaluation of ERα and ERβ significance in breast cancer: state of the art

scientific article published on 01 May 2011

DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation

artículo científico publicado en 2021

Differential expression and comparative subcellular localization of estrogen receptor beta isoforms in virally transformed and normal cultured human lens epithelial cells

artículo científico publicado en 2005

Differential regulation of c-myc by progestins and antiestrogens in T-47D human breast cancer cells

artículo científico publicado en 1991

Differential regulation of estrogen receptors α and β by 4-(E)-{(4-hydroxyphenylimino)-methylbenzene,1,2-diol}, a novel resveratrol analog.

artículo científico publicado en 2014

Differential role of estrogen receptor beta in early versus metastatic non-small cell lung cancer

artículo científico publicado en 2012

ERβ splice variant expression in four large cohorts of human breast cancer patient tumors

artículo científico publicado en 2014

Effects of transforming growth factors and regulation of their mRNA levels in two human endometrial adenocarcinoma cell lines

scientific article published on 01 June 1992

Erratum: The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes

artículo científico publicado en 2016

Estrogen receptor alpha negative breast cancer patients: estrogen receptor beta as a therapeutic target

artículo científico publicado en 2007

Estrogen receptor alpha phosphorylated at tyrosine 537 is associated with poor clinical outcome in breast cancer patients treated with tamoxifen

artículo científico publicado en 2010

Estrogen receptor beta: mine is longer than yours?

scientific article published on 01 October 1998

Estrogen receptor variants and mutations.

artículo científico publicado en 1997

Estrogen receptor variants in human breast cancer

artículo científico publicado en 1990

Estrogen receptor variants in normal human mammary tissue

artículo científico publicado en 1996

Estrogen receptor-alpha mRNA variants in murine and human tissues

scientific article published on 01 December 1999

Estrogen receptor-alpha phosphorylated at Ser118 is present at the promoters of estrogen-regulated genes and is not altered due to HER-2 overexpression

artículo científico publicado en 2006

Estrogen receptor-beta mRNA variants in human and murine tissues

artículo científico publicado en 1998

Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer

artículo científico

Estrogen receptors inhibit Smad3 transcriptional activity through Ap-1 transcription factors

scientific article published on 28 July 2007

Estrogen regulates the association of intermediate filament proteins with nuclear DNA in human breast cancer cells.

artículo científico publicado en 1998

Estrogen regulation of nuclear matrix-intermediate filament proteins in human breast cancer cells

artículo científico publicado en 1996

Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis

artículo científico publicado en 2005

Expression of both estrogen receptor-beta 1 (ER-β1) and its co-regulator steroid receptor RNA activator protein (SRAP) are predictive for benefit from tamoxifen therapy in patients with estrogen receptor-alpha (ER-α)-negative early breast cancer (EB

artículo científico publicado en 2013

Expression of estrogen receptor-beta in human breast tumors

artículo científico publicado en 1997

Expression of insulin-like growth factor binding proteins by T-47D human breast cancer cells: regulation by progestins and antiestrogens

artículo científico publicado en 1994

Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours

artículo científico publicado en 2006

Expression of small breast epithelial mucin (SBEM) protein in tissue microarrays (TMAs) of primary invasive breast cancers

artículo científico publicado en 2008

High-affinity anti-oestrogen binding site distinct from the oestrogen receptor

scientific article published in Nature

Hormonal regulation of proliferation and transforming growth factors gene expression in human endometrial adenocarcinoma xenografts

scientific article published on 01 July 1994

Identification of new human coding steroid receptor RNA activator isoforms

artículo científico publicado en 2003

Identification of novel exon-deleted progesterone receptor variant mRNAs in human breast tissue

scientific article published on 01 November 1996

Immunohistochemical validation of multiple phospho-specific epitopes for estrogen receptor alpha (ERalpha) in tissue microarrays of ERalpha positive human breast carcinomas

artículo científico publicado en 2008

Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides

artículo científico publicado en 2009

Inducible upregulation of oestrogen receptor-beta1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells

artículo científico publicado en 2005

Influence of evolution in tumor biobanking on the interpretation of translational research.

artículo científico publicado en 2008

Inhibition of transcription selectively reduces the level of ubiquitinated histone H2B in chromatin

artículo científico publicado en 1994

Intermittent hypoxia induces proteasome-dependent down-regulation of estrogen receptor alpha in human breast carcinoma

artículo científico publicado en 2004

Intratumoural inflammation and endocrine resistance in breast cancer

artículo científico publicado en 2014

Is oestrogen receptor-beta a predictor of endocrine therapy responsiveness in human breast cancer?

artículo científico publicado en 2006

Lumican and decorin are differentially expressed in human breast carcinoma

artículo científico publicado en 2000

Mammaglobin, a potential marker of breast cancer nodal metastasis

artículo científico publicado en 1999

Measurement of the relative binding affinity of zearalenone, alpha-zearalenol and beta-zearalenol for uterine and oviduct estrogen receptors in swine, rats and chickens: an indicator of estrogenic potencies

artículo científico publicado en 1989

Mechanisms of growth inhibition by antiestrogens and progestins in human breast and endometrial cancer cells

artículo científico publicado el 1 de septiembre de 1992

Mechanisms of oestrogen antagonism by nonsteroidal antioestrogens

artículo científico publicado en 1982

Modifications in the aminoether side chain of clomiphene influence affinity for a specific antiestrogen binding site in MCF 7 cells cytosol

artículo científico publicado en 1981

New insights into estrogen receptor function in human breast cancer

artículo científico publicado en 2003

Novel mutations in the estrogen receptor messenger RNA in human breast cancers

artículo científico publicado en 1996

Oestradiol and progesterone: soluble receptor levels and metabolism in the uterus of the ovariectomized ewe.

artículo científico publicado en 1976

Oestrogen receptor-alpha variant mRNA expression in primary human breast tumours and matched lymph node metastases

artículo científico publicado en 1999

Oncostatin M suppresses oestrogen receptor-α expression and is associated with poor outcome in human breast cancer.

artículo científico publicado en 2012

Phospho-serine-118 estrogen receptor-alpha detection in human breast tumors in vivo

artículo científico publicado en 2004

Phospho-serine-118 estrogen receptor-alpha expression is associated with better disease outcome in women treated with tamoxifen

artículo científico publicado en 2004

Potential role of estrogen receptor alpha (ERalpha) phosphorylated at Serine118 in human breast cancer in vivo

artículo científico publicado en 2006

Preferential estrogen receptor β ligands reduce Bcl-2 expression in hormone-resistant breast cancer cells to increase autophagy.

artículo científico publicado en 2014

Progestin regulation of EGF-receptor mRNA accumulation in T-47D human breast cancer cells

artículo científico publicado en 1988

Psoriasin (S100A7)

artículo científico publicado en 1998

Putative functional characteristics of human estrogen receptor-beta isoforms

artículo científico publicado en 2003

RanBPM interacts with psoriasin in vitro and their expression correlates with specific clinical features in vivo in breast cancer

artículo científico publicado en 2002

Reactive oxygen species induce phosphorylation of serine 118 and 167 on estrogen receptor alpha

artículo científico publicado en 2008

Regulation of c-jun and jun-B by progestins in T-47D human breast cancer cells

artículo científico publicado en 1992

Regulation of transforming growth factor gene expression in human endometrial adenocarcinoma cells

artículo científico publicado en 1992

Relationship between mammaglobin expression and estrogen receptor status in breast tumors

artículo científico publicado en 2003

Relationship of coregulator and oestrogen receptor isoform expression to de novo tamoxifen resistance in human breast cancer

artículo científico publicado en 2002

Role of wild-type estrogen receptor-beta in mitochondrial cytoprotection of cultured normal male and female human lens epithelial cells

artículo científico publicado en 2008

S100 proteins and their influence on pro-survival pathways in cancer

artículo científico publicado en 2004

S100A7 (psoriasin) influences immune response genes in human breast cancer

artículo científico publicado en 2007

S100A7 and the progression of breast cancer

artículo científico publicado en 2004

Stabilisation of the cytoplasmic oestrogen receptor by molybdate

scientific article published on 01 April 1981

Steroid Receptor RNA Activator Protein (SRAP): a potential new prognostic marker for estrogen receptor-positive/node-negative/younger breast cancer patients

artículo científico publicado en 2009

Steroid receptor RNA activator protein (SRAP) expression as a prognostic factor in ER+ human breast tumors

artículo científico publicado en 2013

Steroid receptors in human breast tumorigenesis and breast cancer progression

artículo científico publicado en 2002

Targeted production of proprotein convertase PC1 enhances mammary development and tumorigenesis in transgenic mice

artículo científico publicado en 2009

Targeting the EGFR pathway for cancer therapy

artículo científico publicado en 2006

The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancer

artículo científico publicado en 2005

The effect of estradiol on a 25-hydroxycholecalciferol binding protein in the uterus of the mouse

artículo científico publicado en 1980

The kinome associated with estrogen receptor-positive status in human breast cancer

artículo científico publicado en 2014

The mechanistic target for rapamycin pathway is related to the phosphorylation score for estrogen receptor-α in human breast tumors in vivo

artículo científico publicado en 2014

The pathophysiological role of estrogen receptor variants in human breast cancer.

artículo científico publicado en 1998

The relevance of phosphorylated forms of estrogen receptor in human breast cancer in vivo

artículo científico publicado en 2009

The role of estrogen receptor-β in breast cancer

artículo científico

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes

artículo científico publicado en 2016

Lista de obras de Leigh Murphy

A bi-faceted role of estrogen receptor β in breast cancer

A framework for biobank sustainability

A phosphorylation code for oestrogen receptor-alpha predicts clinical outcome to endocrine therapy in breast cancer

A point mutation in the human estrogen receptor gene is associated with the expression of an abnormal estrogen receptor mRNA containing a 69 novel nucleotide insertion

A practical tool for modeling biospecimen user fees

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

Altered expression of estrogen receptor-alpha variant messenger RNAs between adjacent normal breast and breast tumor tissues

Altered expression of exon 6 deleted progesterone receptor variant mRNA between normal human breast and breast tumour tissues

Analysis of human breast cancer nuclear proteins binding to the promoter elements of the c-myc gene

Antiestrogen action and growth factor regulation

Assay development for the determination of phosphorylation stoichiometry using multiple reaction monitoring methods with and without phosphatase treatment: application to breast cancer signaling pathways

Assessment of multiple different estrogen receptor-beta antibodies for their ability to immunoprecipitate under chromatin immunoprecipitation conditions

C-myc gene chromatin of estrogen receptor positive and negative breast cancer cells

CARM1 is an important determinant of ERα-dependent breast cancer cell differentiation and proliferation in breast cancer cells

Certification for biobanks: the program developed by the Canadian Tumour Repository Network (CTRNet).

Claudin 1 expression in basal-like breast cancer is related to patient age

Claudins 1, 3, and 4 protein expression in ER negative breast cancer correlates with markers of the basal phenotype.

Clinical significance of estrogen receptor phosphorylation ⬇️

Comparative evaluation of ERα and ERβ significance in breast cancer: state of the art

DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation

Differential expression and comparative subcellular localization of estrogen receptor beta isoforms in virally transformed and normal cultured human lens epithelial cells

Differential regulation of c-myc by progestins and antiestrogens in T-47D human breast cancer cells

Differential regulation of estrogen receptors α and β by 4-(E)-{(4-hydroxyphenylimino)-methylbenzene,1,2-diol}, a novel resveratrol analog.

Differential role of estrogen receptor beta in early versus metastatic non-small cell lung cancer

ERβ splice variant expression in four large cohorts of human breast cancer patient tumors

Effects of transforming growth factors and regulation of their mRNA levels in two human endometrial adenocarcinoma cell lines

Erratum: The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes

Estrogen receptor alpha negative breast cancer patients: estrogen receptor beta as a therapeutic target

Estrogen receptor alpha phosphorylated at tyrosine 537 is associated with poor clinical outcome in breast cancer patients treated with tamoxifen

Estrogen receptor beta: mine is longer than yours?

Estrogen receptor variants and mutations.

Estrogen receptor variants in human breast cancer

Estrogen receptor variants in normal human mammary tissue

Estrogen receptor-alpha mRNA variants in murine and human tissues

Estrogen receptor-alpha phosphorylated at Ser118 is present at the promoters of estrogen-regulated genes and is not altered due to HER-2 overexpression

Estrogen receptor-beta mRNA variants in human and murine tissues

Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer

Estrogen receptors inhibit Smad3 transcriptional activity through Ap-1 transcription factors

Estrogen regulates the association of intermediate filament proteins with nuclear DNA in human breast cancer cells.

Estrogen regulation of nuclear matrix-intermediate filament proteins in human breast cancer cells

Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis

Expression of both estrogen receptor-beta 1 (ER-β1) and its co-regulator steroid receptor RNA activator protein (SRAP) are predictive for benefit from tamoxifen therapy in patients with estrogen receptor-alpha (ER-α)-negative early breast cancer (EB

Expression of estrogen receptor-beta in human breast tumors

Expression of insulin-like growth factor binding proteins by T-47D human breast cancer cells: regulation by progestins and antiestrogens

Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours

Expression of small breast epithelial mucin (SBEM) protein in tissue microarrays (TMAs) of primary invasive breast cancers

High-affinity anti-oestrogen binding site distinct from the oestrogen receptor

Hormonal regulation of proliferation and transforming growth factors gene expression in human endometrial adenocarcinoma xenografts

Identification of new human coding steroid receptor RNA activator isoforms

Identification of novel exon-deleted progesterone receptor variant mRNAs in human breast tissue

Immunohistochemical validation of multiple phospho-specific epitopes for estrogen receptor alpha (ERalpha) in tissue microarrays of ERalpha positive human breast carcinomas

Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides

Inducible upregulation of oestrogen receptor-beta1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells

Influence of evolution in tumor biobanking on the interpretation of translational research.

Inhibition of transcription selectively reduces the level of ubiquitinated histone H2B in chromatin

Intermittent hypoxia induces proteasome-dependent down-regulation of estrogen receptor alpha in human breast carcinoma

Intratumoural inflammation and endocrine resistance in breast cancer

Is oestrogen receptor-beta a predictor of endocrine therapy responsiveness in human breast cancer?

Lumican and decorin are differentially expressed in human breast carcinoma

Mammaglobin, a potential marker of breast cancer nodal metastasis

Measurement of the relative binding affinity of zearalenone, alpha-zearalenol and beta-zearalenol for uterine and oviduct estrogen receptors in swine, rats and chickens: an indicator of estrogenic potencies

Mechanisms of growth inhibition by antiestrogens and progestins in human breast and endometrial cancer cells

Mechanisms of oestrogen antagonism by nonsteroidal antioestrogens

Modifications in the aminoether side chain of clomiphene influence affinity for a specific antiestrogen binding site in MCF 7 cells cytosol

New insights into estrogen receptor function in human breast cancer

Novel mutations in the estrogen receptor messenger RNA in human breast cancers

Oestradiol and progesterone: soluble receptor levels and metabolism in the uterus of the ovariectomized ewe.

Oestrogen receptor-alpha variant mRNA expression in primary human breast tumours and matched lymph node metastases

Oncostatin M suppresses oestrogen receptor-α expression and is associated with poor outcome in human breast cancer.

Phospho-serine-118 estrogen receptor-alpha detection in human breast tumors in vivo

Phospho-serine-118 estrogen receptor-alpha expression is associated with better disease outcome in women treated with tamoxifen

Potential role of estrogen receptor alpha (ERalpha) phosphorylated at Serine118 in human breast cancer in vivo

Preferential estrogen receptor β ligands reduce Bcl-2 expression in hormone-resistant breast cancer cells to increase autophagy.

Progestin regulation of EGF-receptor mRNA accumulation in T-47D human breast cancer cells

Psoriasin (S100A7)

Putative functional characteristics of human estrogen receptor-beta isoforms

RanBPM interacts with psoriasin in vitro and their expression correlates with specific clinical features in vivo in breast cancer

Reactive oxygen species induce phosphorylation of serine 118 and 167 on estrogen receptor alpha

Regulation of c-jun and jun-B by progestins in T-47D human breast cancer cells