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Lista de obras de Alexander Dobrovic

"Cancer 2015": A Prospective, Population-Based Cancer Cohort-Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic

artículo científico publicado en 2015

A HindIII RFLP for the HPRT pseudogene on chromosome 3 (HPRTP1).

artículo científico publicado en 1987

A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma

artículo científico publicado en 2014

A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer

artículo científico publicado en 2013

A frequent HindIII RFLP on chromosome 3p21-25 detected by a genomic erbA beta sequence

artículo científico publicado en 1988

A high-throughput protocol for mutation scanning of the BRCA1 and BRCA2 genes

artículo científico publicado en 2011

A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting

scientific article published on 08 October 2009

A multiplex endpoint RT-PCR assay for quality assessment of RNA extracted from formalin-fixed paraffin-embedded tissues

artículo científico publicado en 2010

A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma

artículo científico publicado en 2013

A new approach to primer design for the control of PCR bias in methylation studies

artículo científico publicado en 2008

A novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancer

artículo científico publicado en 2005

A rapid and reliable PCR method for genotyping the ABO blood group

article published in 1993

A rapid and reliable PCR method for genotyping the ABO blood group. II: A2 and O2 alleles

scientific article published on 01 January 1996

A rare translocation (4;11)(q21;p14–15) in an acute lymphoblastic leukemia expressing T-cell and myeloid markers

artículo científico publicado en 1991

A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma

article

A simple, rapid, and sensitive method for the detection of the JAK2 V617F mutation

artículo científico publicado en 2007

Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer

artículo científico publicado en 2011

An optimised direct lysis method for gene expression studies on low cell numbers

artículo científico publicado en 2015

Analysing DNA methylation using bisulphite pyrosequencing

artículo científico publicado en 2011

Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast

artículo científico publicado en 2015

Assessing Gene-Specific Methylation Using HRM-Based Analysis

article

Assessing alternative base substitutions at primer CpG sites to optimise unbiased PCR amplification of methylated sequences

artículo científico publicado en 2017

Assessing combined methylation-sensitive high resolution melting and pyrosequencing for the analysis of heterogeneous DNA methylation

artículo científico publicado en 2011

Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.

artículo científico publicado en 2015

Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumour

artículo científico publicado en 2015

Associations between the IASLC/ATS/ERS lung adenocarcinoma classification and EGFR and KRAS mutations

artículo científico publicado en 2015

BRAF inhibitor-driven tumor proliferation in a KRAS-mutated colon carcinoma is not overcome by MEK1/2 inhibition.

artículo científico publicado en 2013

BRAF/NRAS wild-type melanomas have a high mutation load correlating with histologic and molecular signatures of UV damage

artículo científico publicado en 2013

BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group

artículo científico publicado en 2012

BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype

artículo científico publicado en 2008

Bioinformatics pipelines for targeted resequencing and whole-exome sequencing of human and mouse genomes: a virtual appliance approach for instant deployment

artículo científico publicado en 2014

Characterization of a <i>RAD51C</i>-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance

artículo científico publicado en 2021

Characterization of a KRAB family zinc finger gene, ZNF195, mapping to chromosome band 11p15.5

artículo científico publicado en 1997

Characterization of a novel tumorigenic esophageal adenocarcinoma cell line: OANC1.

artículo científico publicado en 2014

Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma

artículo científico publicado en 2014

Clinical outcome and pathological features associated with NRAS mutation in cutaneous melanoma

artículo científico publicado en 2011

Clinical responses observed with imatinib or sorafenib in melanoma patients expressing mutations in KIT

artículo científico publicado en 2010

Closed-tube PCR methods for locus-specific DNA methylation analysis

artículo científico publicado en 2011

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies

artículo científico publicado en 2016

Clustered somatic mutations are frequent in transcription factor binding sites in melanoma and other cutaneous malignancies

article

Clustering of 1p36 breakpoints distal to 1p36.2 in hematological malignancies

artículo científico publicado en 2001

Comparison of 3 Methodologies for Genotyping of Small Deletion and Insertion Polymorphisms

artículo científico publicado en 2016

Complete molecular response of e6a2 BCR-ABL-positive acute myeloid leukemia to imatinib then dasatinib

artículo científico publicado en 2007

Constitutional methylation of the BRCA1 promoter is specifically associated with BRCA1 mutation-associated pathology in early-onset breast cancer

artículo científico publicado en 2010

Copy number analysis of ductal carcinoma in situ with and without recurrence

artículo científico publicado en 2015

DNA Methylation Profiling of Breast Cancer Cell Lines along the Epithelial Mesenchymal Spectrum-Implications for the Choice of Circulating Tumour DNA Methylation Markers

artículo científico publicado en 2018

DNA ligase-based strategy for quantifying heterogeneous DNA methylation without sequencing.

artículo científico publicado en 2014

DNA methylation analysis of the HIF-1α prolyl hydroxylase domain genes PHD1, PHD2, PHD3 and the factor inhibiting HIF gene FIH in invasive breast carcinomas

artículo científico publicado en 2010

DNA methylation and genetic inactivation at thymidine kinase locus: Two different mechanisms for silencing autosomal genes

article

DNA methylation biomarkers in cancer: progress towards clinical implementation

artículo científico publicado en 2012

DNA methylation in ductal carcinoma in situ of the breast

artículo científico publicado en 2013

DNA methylation of the ABO promoter underlies loss of ABO allelic expression in a significant proportion of leukemic patients

artículo científico publicado en 2009

DNA methylation profiling of breast cancer cell lines along the epithelial mesenchymal spectrum - implications for the choice of circulating tumour DNA methylation markers

article published in 2017

DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast

DNA methylation, epimutations and cancer predisposition

artículo científico publicado en 2008

DNA repair gene inactivation in non-Hodgkin's lymphoma

article

Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders

artículo científico

Detection of MGMT promoter methylation in normal individuals is strongly associated with the T allele of the rs16906252 MGMT promoter single nucleotide polymorphism

artículo científico publicado en 2009

Detection of NPM1 exon 12 mutations and FLT3 - internal tandem duplications by high resolution melting analysis in normal karyotype acute myeloid leukemia

artículo científico publicado en 2008

Detection of circulating tumor cells in colorectal cancer by immunobead-PCR is a sensitive prognostic marker for relapse of disease

artículo científico publicado en 1995

Detection of the molecular abnormality in chronic myeloid leukemia by use of the polymerase chain reaction

artículo científico publicado en 1988

Detection of the transforming AKT1 mutation E17K in non-small cell lung cancer by high resolution melting

artículo científico publicado en 2008

Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome

artículo científico publicado en 2014

Digital PCR of Genomic Rearrangements for Monitoring Circulating Tumour DNA.

artículo científico publicado en 2016

Direct genotyping of single nucleotide polymorphisms in methyl metabolism genes using probe-free high-resolution melting analysis

artículo científico publicado en 2008

Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma

artículo científico publicado en 2006

Docetaxel plus cetuximab as second-line treatment for docetaxel-refractory oesophagogastric cancer: the AGITG ATTAX2 trial

artículo científico publicado en 2013

Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil- DNA glycosylase

artículo científico publicado en 2012

Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer

artículo científico publicado en 2012

EGFR gene copy number alterations are not a useful screening tool for predicting EGFR mutation status in lung adenocarcinoma

artículo científico publicado en 2014

Erratum

artículo científico publicado en 1994

Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat

artículo científico publicado en 2015

Fc-γ Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer.

artículo científico publicado en 2016

Fusion of the NUP98 gene with the LEDGF/p52 gene defines a recurrent acute myeloid leukemia translocation

artículo científico publicado en 2001

GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly

GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly.

artículo científico publicado en 2017

Gene mapping in marsupials and monotremes. II. Assignments to the X chromosome of dasyurid marsupials

article

Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas

artículo científico publicado en 2016

Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver

artículo científico publicado en 2014

Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis.

artículo científico publicado en 2016

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

artículo científico publicado en 2010

Heterozygosity for the common perforin mutation, p.A91V, impairs the cytotoxicity of primary natural killer cells from healthy individuals

High frequency of germline TP53 mutations in a prospective adult-onset sarcoma cohort

artículo científico publicado en 2013

High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies

artículo científico publicado en 2008

High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer.

artículo científico publicado en 2006

High resolution melting for mutation scanning of TP53 exons 5-8

artículo científico publicado en 2007

High-Resolution Assessment of Copy Number Variation

Identification of circulating tumour cells in early stage breast cancer patients using multi marker immunobead RT-PCR

artículo científico publicado en 2009

Immunobead-PCR: a technique for the detection of circulating tumor cells using immunomagnetic beads and the polymerase chain reaction

artículo científico publicado en 1993

Imprinting and loss of ABO antigens in leukemia

artículo científico publicado en 1993

In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.

artículo científico publicado en 2008

In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.

artículo científico publicado en 2009

Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer

artículo científico publicado en 2007

Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer.

artículo científico publicado en 2011

Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors

artículo científico publicado en 2013

Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome

artículo científico publicado en 2011

KIT immunohistochemistry and mutation status in gastrointestinal stromal tumours (GISTs) evaluated for treatment with imatinib.

artículo científico publicado en 2006

Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies

artículo científico publicado en 2009

Localization of the human growth arrest-specific gene (GAS1) to chromosome bands 9q21.3-q22, a region frequently deleted in myeloid malignancies

artículo científico publicado en 1993

Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines

artículo científico publicado en 2014

Loss of heterozygosity in a gene coding for a thyroid hormone receptor in lung cancers

artículo científico publicado en 1989

Loss of red cell A, B, and H antigens is frequent in myeloid malignancies

article

Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine.

artículo científico publicado en 2014

Mapping of the chromosome 11 breakpoint of the t(4;11)(q21;p14–15) translocation

scientific article published on 01 September 1993

Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status i

artículo científico publicado en 2012

Melting curve assays for DNA methylation analysis

artículo científico publicado en 2009

MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing

artículo científico publicado en 2016

Methylation analysis of formalin-fixed, paraffin-embedded sections using a nontoxic DNA extraction protocol

article

Methylation of the BRCA1 gene in sporadic breast cancer ⬇️

artículo científico publicado el 15 de agosto de 1997

Methylation profiling of ductal carcinoma in situ and its relationship to histopathological features

artículo científico publicado en 2014

Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes

artículo científico publicado en 2012

Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation

artículo científico publicado en 2007

Methylation-sensitive high-resolution melting

Methylation-sensitive, single-strand conformation analysis (MS-SSCA): A rapid method to screen for and analyze methylation

artículo científico publicado en 1999

Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value.

artículo científico

Molecular analysis of the Philadelphia chromosome

artículo científico publicado en 1991

Molecular detection of blood-borne epithelial cells in colorectal cancer patients and in patients with benign bowel disease

artículo científico publicado en 2000

Molecular detection of residual lymphoma cells in peripheral blood stem cell harvests and following autologous transplantation

scientific article published on 01 January 1993

Monitoring response to therapy in melanoma by quantifying circulating tumour DNA with droplet digital PCR for BRAF and NRAS mutations.

artículo científico publicado en 2015

Multicenter randomized, open-label phase II trial of sequential erlotinib and gemcitabine compared with gemcitabine monotherapy as first-line therapy in elderly or ECOG PS two patients with advanced NSCLC.

artículo científico publicado en 2014

Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations

artículo científico publicado en 2014

Mutations in KIT occur at low frequency in melanomas arising from anatomical sites associated with chronic and intermittent sun exposure

artículo científico publicado en 2010

Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers

artículo científico publicado en 2006

Negative selection of chronic lymphocytic leukaemia cells using a bifunctional rosette-based antibody cocktail

artículo científico publicado en 2008

No evidence for DNA methylation of the ATM promoter CpG island in chronic lymphocytic leukemia

artículo científico publicado en 2012

No evidence for DNA methylation of von Hippel-Lindau ubiquitin ligase complex genes in breast cancer

artículo científico publicado en 2010

No evidence for PALB2 methylation in high-grade serous ovarian cancer

artículo científico publicado en 2013

No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer

artículo científico publicado en 2009

Nonequivalent gene expression and copy number alterations in high-grade serous ovarian cancers with BRCA1 and BRCA2 mutations

artículo científico publicado en 2013

Nuclear HIF1A expression is strongly prognostic in sporadic but not familial male breast cancer

artículo científico publicado en 2014

Optimisation of the RT-PCR detection of immunomagnetically enriched carcinoma cells

artículo científico publicado en 2002

PIK3CA mutations are frequently observed in BRCAX but not BRCA2-associated male breast cancer

artículo científico publicado en 2013

Pathological response of gastrointestinal stromal tumour to imatinib treatment correlates with tumourKITmutational status in individual tumour clones

article

Polyclonal Resistance in Gastrointestinal Stromal Tumor Treated with Sequential Kinase Inhibitors

Prevalence and natural history of ALK positive non-small-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors

artículo científico publicado en 2014

Probe-Free Digital PCR Quantitative Methodology to Measure Donor-Specific Cell-Free DNA after Solid-Organ Transplantation

artículo científico publicado en 2017

Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma

artículo científico publicado en 2000

Publisher Correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma

artículo científico publicado en 2020

Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome

artículo científico publicado en 2014

Quantitative threefold allele-specific PCR (QuanTAS-PCR) for highly sensitive JAK2 V617F mutant allele detection

artículo científico publicado en 2013

Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene

artículo científico publicado en 2008

Rapid detection of FLT3 exon 20 tyrosine kinase domain mutations in patients with acute myeloid leukemia by high-resolution melting analysis

artículo científico publicado en 2012

Rapid detection of carriers with BRCA1 and BRCA2 mutations using high resolution melting analysis

artículos científicos

Rapid detection of methylation change at H19 in human imprinting disorders using methylation-sensitive high-resolution melting

article by Tomasz K. Wojdacz et al published October 2008 in Human Mutation

Rarity of AKT1 and AKT3 E17K mutations in squamous cell carcinoma of lung

artículo científico publicado en 2010

Recurrent coiled-coil motifs in NUP98 fusion partners provide a clue to leukemogenesis

artículo científico publicado en 2002

Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer

artículo científico publicado en 2017

Reducing Sequence Artifacts in Amplicon-Based Massively Parallel Sequencing of Formalin-Fixed Paraffin-Embedded DNA by Enzymatic Depletion of Uracil-Containing Templates

artículo científico publicado en 2013

Relationship between M-BCR breakpoint position in blast crisis and length of chronic phase in chronic myeloid leukemia

artículo científico publicado en 1992

Role of p53 in the progression of gastric cancer

artículo científico publicado en 2014

SCL gene in human tumors.

artículo científico publicado en 1992

Screening for and analysis of methylation differences using methylation-sensitive single-strand conformation analysis

article

Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf

artículo científico publicado en 2009

Sensitive Melting Analysis after Real Time- Methylation Specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection

artículo científico publicado en 2008

Sensitive detection of KIT D816V in patients with mastocytosis

artículo científico publicado en 2006

Sensitive quantification of somatic mutations using molecular inversion probes

artículo científico publicado en 2011

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing

artículo científico publicado en 2014

Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization

artículo científico publicado en 2014

Significance of molecular marker-positive cells after autologous peripheral-blood stem-cell transplantation for non-Hodgkin's lymphoma

artículo científico publicado en 1995

Somatic mutations, acetylator status, and prognosis in colorectal cancer

artículo científico publicado en 1998

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours

artículo científico publicado en 2013

Temporal changes of EGFR mutations and T790M levels in tumour and plasma DNA following AZD9291 treatment.

artículo científico publicado en 2016

The (4;11)(q21;p15) translocation fuses the NUP98 and RAP1GDS1 genes and is recurrent in T-cell acute lymphocytic leukemia

artículo científico publicado en 1999

The clinical relevance of pathologic subtypes in metastatic lung adenocarcinoma

artículo científico publicado en 2014

The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression

artículo científico publicado en 2011

The fusion partner specifies the oncogenic potential of NUP98 fusion proteins

scientific article published on 21 September 2013

The implications of heterogeneous DNA methylation for the accurate quantification of methylation

artículo científico publicado en 2010

The role of BRAF mutations in primary melanoma growth rate and survival

artículo científico publicado en 2015

The significance of oncogene amplification in primary breast cancer

artículo científico publicado en 1989

Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer

artículo científico publicado en 2000

Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers.

artículo científico publicado en 2012

Validation of a primer optimisation matrix to improve the performance of reverse transcription - quantitative real-time PCR assays

artículo científico publicado en 2009

Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer

artículo científico publicado en 2002

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma

artículo científico publicado en 2015

Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

artículo científico publicado en 2009

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