Lista de obras - Roberto Furlan - Dominio Público Uruguay

2D immunomic approach for the study of IgG autoantibodies in the experimental model of multiple sclerosis

article

A Single Nucleotide ADA Genetic Variant Is Associated to Central Inflammation and Clinical Presentation in MS: Implications for Cladribine Treatment

scientific article published on 30 September 2020

A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers.

artículo científico publicado en 2016

A nitric oxide releasing derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis

artículo científico publicado en 2004

Abnormal NMDA receptor function exacerbates experimental autoimmune encephalomyelitis

artículo científico publicado en 2013

Abnormal activity of the Na/Ca exchanger enhances glutamate transmission in experimental autoimmune encephalomyelitis

artículo científico publicado en 2010

Absence of an intrathecal immune reaction to a helper-dependent adenoviral vector delivered into the cerebrospinal fluid of non-human primates.

artículo científico publicado en 2007

Absence of central nervous system pathology in severe combined immunodeficiency mice intraperitoneally injected with peripheral blood lymphocytes from multiple sclerosis patients

artículo científico publicado en 1994

Absence of oligoclonally restricted immunoglobulins in tears from multiple sclerosis patients

artículo científico publicado en 1993

Acid sphingomyelinase activity triggers microparticle release from glial cells

artículo científico publicado en 2009

Acid sphingomyelinase activity triggers microparticle release from glial cells

Activated macrophages release microvesicles containing polarized M1 or M2 mRNAs

artículo científico publicado en 2013

Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma

scientific article published on 01 July 2003

Administration of a monomeric CCL2 variant to EAE mice inhibits inflammatory cell recruitment and protects from demyelination and axonal loss

artículo científico publicado en 2009

Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica

artículo científico publicado en 2014

Alpha-lipoic acid is effective in prevention and treatment of experimental autoimmune encephalomyelitis.

artículo científico publicado en 2004

Altered miRNA expression in T regulatory cells in course of multiple sclerosis

artículo científico publicado en 2010

Animal models of multiple sclerosis

artículo científico publicado en 2009

Antiacquaporin 4 antibodies detection by different techniques in neuromyelitis optica patients.

artículo científico publicado en 2009

Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis.

artículo científico publicado en 2018

Beta endorphin concentrations in PBMC of patients with different clinical phenotypes of multiple sclerosis.

artículo científico publicado en 2003

Calcitonin gene-related peptide decreases IL-1beta, IL-6 as well as Ym1, Arg1, CD163 expression in a brain tissue context-dependent manner while ameliorating experimental autoimmune encephalomyelitis

article

Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis

artículo científico publicado en 2011

Cell-based remyelinating therapies in multiple sclerosis: evidence from experimental studies

artículo científico publicado en 2004

Cellular magnetic resonance with iron oxide nanoparticles: long-term persistence of SPIO signal in the CNS after transplanted cell death.

artículo científico publicado en 2014

Central nervous system delivery of interleukin 4 by a nonreplicative herpes simplex type 1 viral vector ameliorates autoimmune demyelination

scientific article published on 01 November 1998

Central nervous system gene therapy with interleukin-4 inhibits progression of ongoing relapsing-remitting autoimmune encephalomyelitis in Biozzi AB/H mice.

artículo científico publicado en 2001

Cerebrospinal Fluid Analysis in Immunoglobulin G4-related Hypertrophic Pachymeningitis

article

Cerebrospinal fluid detection of interleukin-1β in phase of remission predicts disease progression in multiple sclerosis

scientific article published on 18 February 2014

Characterization of immune cell subsets during the active phase of multiple sclerosis reveals disease and c-Jun N-terminal kinase pathway biomarkers.

artículo científico publicado en 2010

Classical and unconventional pathways of vesicular release in microglia

artículo científico

Clinical significance of the number of oligoclonal bands in patients with clinically isolated syndromes

artículo científico publicado en 2015

Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice

artículo científico publicado en 2015

Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study.

artículo científico publicado en 2015

Cxcl10 enhances blood cells migration in the sub-ventricular zone of mice affected by experimental autoimmune encephalomyelitis

artículo científico publicado en 2009

Cytokine therapy in immune-mediated demyelinating diseases of the central nervous system: a novel gene therapy approach

artículo científico publicado en 2000

Cytokines and immunity in multiple sclerosis: the dual signal hypothesis.

artículo científico publicado en 2000

Definition of non-responders: biological markers

scientific article published on September 2008

Delivery to the central nervous system of a nonreplicative herpes simplex type 1 vector engineered with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune encephalomyelitis

artículo científico publicado en 2001

Dendritic cells loaded with apoptotic oligodendrocytes as a source of myelin T-cell epitopes in multiple sclerosis

artículo científico publicado en 2008

Diagnostic value of IgG4 Indices in IgG4-related hypertrophic pachymeningitis

artículo científico publicado en 2013

Distinct Protein Expression Networks are Activated in Microglia Cells after Stimulation with IFN-γ and IL-4

artículo científico publicado en 2019

Early relapses after the first dose of natalizumab in active multiple sclerosis patients

artículo científico publicado en 2008

Effects of isoxazolo-pyridinone 7e, a potent activator of the Nurr1 signaling pathway, on experimental autoimmune encephalomyelitis in mice

artículo científico publicado en 2014

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

artículo científico publicado en 2016

Exercise attenuates the clinical, synaptic and dendritic abnormalities of experimental autoimmune encephalomyelitis.

artículo científico publicado en 2009

Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages

artículo científico publicado en 2015

Extracellular vesicles in Alzheimer's disease: friends or foes? Focus on aβ-vesicle interaction

artículo científico publicado en 2015

Fibroblast growth factor-II gene therapy reverts the clinical course and the pathological signs of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice.

artículo científico publicado en 2001

Free Light Chains and Intrathecal B Cells Activity in Multiple Sclerosis: A Prospective Study and Meta-Analysis.

artículo científico publicado en 2016

Gene therapy-mediated modulation of immune processes in the central nervous system

artículo científico publicado en 2003

Growth factors and synaptic plasticity in relapsing-remitting multiple sclerosis.

artículo científico publicado en 2014

HSV-1-mediated IL-1 receptor antagonist gene therapy ameliorates MOG(35-55)-induced experimental autoimmune encephalomyelitis in C57BL/6 mice.

artículo científico publicado en 2006

HTLV-I hu-SCID mouse in the study of HTLV-I neurotropism

artículo científico publicado en 1994

Highlights from the Seventh International Congress of the International Society of Neuroimmunology.

artículo científico publicado en 2005

Human T-cell lymphotropic virus type-I infection in the severe combined immunodeficiency mouse

artículo científico publicado en 1996

IL-17- and IFN-γ-secreting Foxp3+ T cells infiltrate the target tissue in experimental autoimmunity.

artículo científico publicado en 2010

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression.

artículo científico publicado en 2017

IL4 gene delivery to the CNS recruits regulatory T cells and induces clinical recovery in mouse models of multiple sclerosis.

artículo científico publicado en 2008

IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo

artículo científico publicado en 2016

Immunological patterns identifying disease course and evolution in multiple sclerosis patients

Impaired striatal GABA transmission in experimental autoimmune encephalomyelitis

article

In vivo fate analysis reveals the multipotent and self-renewal features of embryonic AspM expressing cells.

artículo científico publicado en 2011

Increased M1/decreased M2 signature and signs of Th1/Th2 shift in chronic patients with bipolar disorder, but not in those with schizophrenia

artículo científico publicado en 2014

Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis

artículo científico publicado en 2009

Interferon-β treatment in multiple sclerosis patients decreases the number of circulating T cells producing interferon-γ and interleukin-4

artículo científico publicado en 2000

Interleukin-1β Alters Hebbian Synaptic Plasticity in Multiple Sclerosis

scientific article published on 23 September 2020

Interleukin-1β causes synaptic hyperexcitability in multiple sclerosis

artículo científico publicado en 2012

Interleukin-1β promotes long-term potentiation in patients with multiple sclerosis.

artículo científico publicado en 2013

Interleukin-8 is associated with acute and persistent dysfunction after optic neuritis

artículo científico publicado en 2014

Involvement of calcitonin gene-related peptide and receptor component protein in experimental autoimmune encephalomyelitis

artículo científico publicado en 2014

KIR2DL2 inhibitory pathway enhances Th17 cytokine secretion by NK cells in response to herpesvirus infection in multiple sclerosis patients.

artículo científico publicado en 2016

Lab-on-Chip for Exosomes and Microvesicles Detection and Characterization

scholarly article by Maria Serena Chiriacò et al published 20 September 2018 in Sensors

Lentiviral-mediated administration of IL-25 in the CNS induces alternative activation of microglia

artículo científico publicado en 2012

Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM).

artículo científico publicado en 1999

Metallothioneins as dynamic markers for brain disease in lysosomal disorders

artículo científico publicado en 2014

Method for intracellular magnetic labeling of human mononuclear cells using approved iron contrast agents

scientific article published on 01 December 1999

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles.

scientific article published on 13 December 2013

Microglial microvesicle secretion and intercellular signaling.

artículo científico

Microvesicles: What is the Role in Multiple Sclerosis?

artículo científico

Microvesicles: novel biomarkers for neurological disorders

artículo científico publicado en 2012

Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis.

artículo científico publicado en 2013

Monoclonal Antibodies Conjugated with Superparamagnetic Iron Oxide Particles Allow Magnetic Resonance Imaging Detection of Lymphocytes in the Mouse Brain

scholarly article by Alessandro Luchetti et al published March 2012 in Molecular imaging : official journal of the Society for Molecular Imaging

Monocytes P2X7 purinergic receptor is modulated by glatiramer acetate in multiple sclerosis

scientific article published on 26 February 2012

Multifaceted aspects of inflammation in multiple sclerosis: the role of microglia.

artículo científico publicado en 2007

Mutational analysis identifies residues crucial for homodimerization of myeloid differentiation factor 88 (MyD88) and for its function in immune cells.

artículo científico publicado en 2013

Myeloid Extracellular Vesicles: Messengers from the Demented Brain

artículo científico publicado en 2016

Myeloid microvesicles are a marker and therapeutic target for neuroinflammation

artículo científico publicado en 2012

Myeloid microvesicles in cerebrospinal fluid are associated with myelin damage and neuronal loss in mild cognitive impairment and Alzheimer disease

NG2, a common denominator for neuroinflammation, blood-brain barrier alteration, and oligodendrocyte precursor response in EAE, plays a role in dendritic cell activation

artículo científico publicado en 2016

Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex

artículo científico publicado en 2014

Neuromyelitis optica: concepts in evolution

artículo científico publicado en 2010

Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism.

artículo científico publicado en 2005

Oral fingolimod rescues the functional deficits of synapses in experimental autoimmune encephalomyelitis

artículo científico publicado en 2012

Oxidative stress is differentially present in multiple sclerosis courses, early evident, and unrelated to treatment

artículo científico publicado en 2014

Pentraxin-3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease

artículo científico publicado en 2015

Potential role of IL-13 in neuroprotection and cortical excitability regulation in multiple sclerosis.

artículo científico publicado en 2011

Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis

artículo científico publicado en 2023

Proteomic identification of aldolase A as an autoantibody target in patients with atypical movement disorders

artículo científico publicado en 2012

Radiobinding assay for detecting autoantibodies to single epitopes

artículo científico publicado en 2008

Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation.

artículo científico publicado en 2010

Secondary progressive multiple sclerosis: current knowledge and future challenges

artículo científico publicado en 2006

Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies

artículo científico publicado en 2001

Subclinical central inflammation is risk for RIS and CIS conversion to MS

artículo científico publicado en 2015

Synapsin I deletion reduces neuronal damage and ameliorates clinical progression of experimental autoimmune encephalomyelitis.

artículo científico publicado en 2017

Synaptic plasticity and PDGF signaling defects underlie clinical progression in multiple sclerosis.

artículo científico publicado en 2013

T helper 9 cells induced by plasmacytoid dendritic cells regulate interleukin-17 in multiple sclerosis

artículo científico publicado en 2015

T regulatory cells are markers of disease activity in multiple sclerosis patients

artículo científico publicado en 2011

The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis

artículo científico publicado en 2007

The ependymal route to the CNS: an emerging gene-therapy approach for MS.

artículo científico publicado en 2001

The link between inflammation, synaptic transmission and neurodegeneration in multiple sclerosis.

artículo científico publicado en 2009

The therapeutic effect of mesenchymal stem cell transplantation in experimental autoimmune encephalomyelitis is mediated by peripheral and central mechanisms

artículo científico

The therapeutic use of gene therapy in inflammatory demyelinating diseases of the central nervous system

artículo científico publicado en 2003

Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

artículo científico publicado en 2017

Tumor necrosis factor is elevated in progressive multiple sclerosis and causes excitotoxic neurodegeneration

artículo científico publicado en 2013

Vaccination with amyloid-beta peptide induces autoimmune encephalomyelitis in C57/BL6 mice

artículo científico publicado en 2003

Vitamin D levels and risk of multiple sclerosis in patients with clinically isolated syndromes

artículo científico publicado en 2013

Lista de obras de Roberto Furlan

2D immunomic approach for the study of IgG autoantibodies in the experimental model of multiple sclerosis

A Single Nucleotide ADA Genetic Variant Is Associated to Central Inflammation and Clinical Presentation in MS: Implications for Cladribine Treatment

A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers.

A nitric oxide releasing derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis

Abnormal NMDA receptor function exacerbates experimental autoimmune encephalomyelitis

Abnormal activity of the Na/Ca exchanger enhances glutamate transmission in experimental autoimmune encephalomyelitis

Absence of an intrathecal immune reaction to a helper-dependent adenoviral vector delivered into the cerebrospinal fluid of non-human primates.

Absence of central nervous system pathology in severe combined immunodeficiency mice intraperitoneally injected with peripheral blood lymphocytes from multiple sclerosis patients

Absence of oligoclonally restricted immunoglobulins in tears from multiple sclerosis patients

Acid sphingomyelinase activity triggers microparticle release from glial cells

Acid sphingomyelinase activity triggers microparticle release from glial cells

Activated macrophages release microvesicles containing polarized M1 or M2 mRNAs

Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma

Administration of a monomeric CCL2 variant to EAE mice inhibits inflammatory cell recruitment and protects from demyelination and axonal loss

Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica

Alpha-lipoic acid is effective in prevention and treatment of experimental autoimmune encephalomyelitis.

Altered miRNA expression in T regulatory cells in course of multiple sclerosis

Animal models of multiple sclerosis

Antiacquaporin 4 antibodies detection by different techniques in neuromyelitis optica patients.

Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis.

Beta endorphin concentrations in PBMC of patients with different clinical phenotypes of multiple sclerosis.

Calcitonin gene-related peptide decreases IL-1beta, IL-6 as well as Ym1, Arg1, CD163 expression in a brain tissue context-dependent manner while ameliorating experimental autoimmune encephalomyelitis

Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis

Cell-based remyelinating therapies in multiple sclerosis: evidence from experimental studies

Cellular magnetic resonance with iron oxide nanoparticles: long-term persistence of SPIO signal in the CNS after transplanted cell death.

Central nervous system delivery of interleukin 4 by a nonreplicative herpes simplex type 1 viral vector ameliorates autoimmune demyelination

Central nervous system gene therapy with interleukin-4 inhibits progression of ongoing relapsing-remitting autoimmune encephalomyelitis in Biozzi AB/H mice.

Cerebrospinal Fluid Analysis in Immunoglobulin G4-related Hypertrophic Pachymeningitis

Cerebrospinal fluid detection of interleukin-1β in phase of remission predicts disease progression in multiple sclerosis

Characterization of immune cell subsets during the active phase of multiple sclerosis reveals disease and c-Jun N-terminal kinase pathway biomarkers.

Classical and unconventional pathways of vesicular release in microglia

Clinical significance of the number of oligoclonal bands in patients with clinically isolated syndromes

Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice

Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study.

Cxcl10 enhances blood cells migration in the sub-ventricular zone of mice affected by experimental autoimmune encephalomyelitis

Cytokine therapy in immune-mediated demyelinating diseases of the central nervous system: a novel gene therapy approach

Cytokines and immunity in multiple sclerosis: the dual signal hypothesis.

Definition of non-responders: biological markers

Delivery to the central nervous system of a nonreplicative herpes simplex type 1 vector engineered with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune encephalomyelitis

Dendritic cells loaded with apoptotic oligodendrocytes as a source of myelin T-cell epitopes in multiple sclerosis

Diagnostic value of IgG4 Indices in IgG4-related hypertrophic pachymeningitis

Distinct Protein Expression Networks are Activated in Microglia Cells after Stimulation with IFN-γ and IL-4

Early relapses after the first dose of natalizumab in active multiple sclerosis patients

Effects of isoxazolo-pyridinone 7e, a potent activator of the Nurr1 signaling pathway, on experimental autoimmune encephalomyelitis in mice

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

Exercise attenuates the clinical, synaptic and dendritic abnormalities of experimental autoimmune encephalomyelitis.

Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages

Extracellular vesicles in Alzheimer's disease: friends or foes? Focus on aβ-vesicle interaction

Fibroblast growth factor-II gene therapy reverts the clinical course and the pathological signs of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice.

Free Light Chains and Intrathecal B Cells Activity in Multiple Sclerosis: A Prospective Study and Meta-Analysis.

Gene therapy-mediated modulation of immune processes in the central nervous system

Growth factors and synaptic plasticity in relapsing-remitting multiple sclerosis.

HSV-1-mediated IL-1 receptor antagonist gene therapy ameliorates MOG(35-55)-induced experimental autoimmune encephalomyelitis in C57BL/6 mice.

HTLV-I hu-SCID mouse in the study of HTLV-I neurotropism

Highlights from the Seventh International Congress of the International Society of Neuroimmunology.

Human T-cell lymphotropic virus type-I infection in the severe combined immunodeficiency mouse

IL-17- and IFN-γ-secreting Foxp3+ T cells infiltrate the target tissue in experimental autoimmunity.

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression.

IL4 gene delivery to the CNS recruits regulatory T cells and induces clinical recovery in mouse models of multiple sclerosis.

IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo

Immunological patterns identifying disease course and evolution in multiple sclerosis patients

Impaired striatal GABA transmission in experimental autoimmune encephalomyelitis

In vivo fate analysis reveals the multipotent and self-renewal features of embryonic AspM expressing cells.

Increased M1/decreased M2 signature and signs of Th1/Th2 shift in chronic patients with bipolar disorder, but not in those with schizophrenia

Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis

Interferon-β treatment in multiple sclerosis patients decreases the number of circulating T cells producing interferon-γ and interleukin-4

Interleukin-1β Alters Hebbian Synaptic Plasticity in Multiple Sclerosis

Interleukin-1β causes synaptic hyperexcitability in multiple sclerosis

Interleukin-1β promotes long-term potentiation in patients with multiple sclerosis.

Interleukin-8 is associated with acute and persistent dysfunction after optic neuritis

Involvement of calcitonin gene-related peptide and receptor component protein in experimental autoimmune encephalomyelitis

KIR2DL2 inhibitory pathway enhances Th17 cytokine secretion by NK cells in response to herpesvirus infection in multiple sclerosis patients.

Lab-on-Chip for Exosomes and Microvesicles Detection and Characterization

Lentiviral-mediated administration of IL-25 in the CNS induces alternative activation of microglia

Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM).

Metallothioneins as dynamic markers for brain disease in lysosomal disorders

Method for intracellular magnetic labeling of human mononuclear cells using approved iron contrast agents

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles.

Microglial microvesicle secretion and intercellular signaling.