Lista de obras - Patrick M. Nolan - Dominio Público Uruguay

A comparison of physiological and behavioural parameters in C57BL/6J mice undergoing food or water restriction regimes

artículo científico publicado en 2006

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

artículo científico publicado en 2014

A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice

artículo científico publicado en 2009

A twin and molecular genetics study of sleep paralysis and associated factors

artículo científico publicado en 2015

Acquisition of a brief behavioral experience in the presence of neuron-specific and D2-CAM/N-CAM-specific antisera

artículo científico publicado en 1987

Acquisition of a brief behavioural experience in the rat is inhibited by the brain-specific monoclonal antibody, F3-87-8.

artículo científico publicado en 1987

Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System

artículo científico publicado en 2016

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

artículo científico publicado en 2015

Assessing mouse behaviour throughout the light/dark cycle using automated in-cage analysis tools

artículo científico publicado en 2017

Clocks go forward: progress in the molecular genetic analysis of rhythmic behaviour

artículo científico publicado en 2009

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

artículo científico publicado en 2012

Cognitive assessment of mice strains heterozygous for cell-adhesion genes reveals strain-specific alterations in timing

artículo científico publicado en 2014

Defining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse model

artículo científico publicado en 2007

Dibutyryl cyclic AMP stimulates expression of ependymin mRNA and the synthesis and release of the protein into the culture medium by neuroblastoma cells (NB2a/d1).

artículo científico publicado en 1992

Differential roles for cryptochromes in the mammalian retinal clock

artículo científico publicado en 2018

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

artículo científico publicado en 2017

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

artículo científico publicado en 2005

Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.

artículo científico publicado en 2013

Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features

artículo científico publicado en 2014

ENU mutagenesis in the mouse: application to human genetic disease

artículo científico publicado en 2002

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.

artículo científico publicado en 2016

Early motor deficits in mouse disease models are reliably uncovered using an automated home-cage wheel-running system: a cross-laboratory validation.

artículo científico publicado en 2014

Forward genetics identifies a novel sleep mutant with sleep state inertia and REM sleep deficits

artículo científico publicado en 2020

Gene-environment interactions differentially affect mouse strain behavioral parameters

artículo científico publicado en 2006

Generation of mouse mutants as tools in dissecting the molecular clock

artículo científico publicado en 2012

Genetic and molecular analysis of the central and peripheral circadian clockwork of mice

artículo científico publicado en 2007

Genetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep

artículo científico publicado en 2014

Hippocampal NCAM180 transiently increases sialylation during the acquisition and consolidation of a passive avoidance response in the adult rat.

artículo científico publicado en 1992

Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits

artículo científico publicado en 2008

Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.

artículo científico publicado en 2000

Inducible Knockout of Mouse Zfhx3 Emphasizes Its Key Role in Setting the Pace and Amplitude of the Adult Circadian Clock

artículo científico publicado en 2017

Informatics for mutagenesis: the design of mutabase--a distributed data recording system for animal husbandry, mutagenesis, and phenotypic analysis

artículo científico publicado en 2000

KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility

artículo científico publicado en 2012

Learning-induced change in neural activity during acquisition and consolidation of a passive avoidance response in the rat.

artículo científico publicado en 1990

Loss of disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities

artículo científico publicado en 2019

Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light

artículo científico publicado en 2016

Meta-analysis of transcriptomic datasets identifies genes enriched in the mammalian circadian pacemaker.

artículo científico publicado en 2017

Mouse mutagenesis-systematic studies of mammalian gene function

artículo científico publicado en 1998

Mutagenesis and behavioral screening for altered circadian activity identifies the mouse mutant, Wheels

scientific article published on 01 December 1995

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

artículo científico publicado en 2003

Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse

artículo científico publicado en 2002

Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans

artículo científico publicado en 2007

Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland

scientific journal article

N-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders

artículo científico publicado en 2003

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

artículo científico publicado en 2016

Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2.

artículo científico publicado en 2007

Novel phenotypes identified by plasma biochemical screening in the mouse

artículo científico publicado en 2002

Overexpression of Fto leads to increased food intake and results in obesity

artículo científico publicado en 2010

Phenotyping first-generation genome editing mutants: a new standard?

artículo científico publicado en 2017

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures

artículo científico publicado en 2014

Random mutagenesis screen for dominant behavioral mutations in mice

artículo científico

Reaching and grasping phenotypes in the mouse (Mus musculus): a characterization of inbred strains and mutant lines

scientific article published on 15 June 2007

Reciprocal interactions between circadian clocks and aging

artículo científico publicado en 2016

Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours

artículo científico publicado en 2012

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

artículo científico publicado en 2008

Replication of Genome-Wide Association Studies (GWAS) loci for sleep in the British G1219 cohort

artículo científico publicado en 2013

Running endurance abnormality in mdx mice

artículo científico publicado en 2002

Screening for novel ENU-induced rhythm, entrainment and activity mutants.

artículo científico publicado en 2004

Sleep-like behavior and 24-h rhythm disruption in the Tc1 mouse model of Down syndrome

artículo científico publicado en 2015

Soluble rat brain sialidase does not influence intracellular glycosylation of Golgi sialyltransferase or its constitutive glycoproteins

scientific article published on 01 June 1988

Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo

artículo científico publicado en 2011

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

scientific journal article

The Wheels mutation in the mouse causes vascular, hindbrain, and inner ear defects

artículo científico publicado en 2001

The Zfhx3-Mediated Axis Regulates Sleep and Interval Timing in Mice

artículo científico publicado en 2016

The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis

artículo científico publicado en 2017

The guanine nucleotide exchange factor, Spata13, influences social behaviour and nocturnal activity

scientific article published on 24 April 2019

The role of mutagenesis in defining genes in behaviour

artículo científico publicado en 2006

Three novel pigmentation mutants generated by genome-wide random ENU mutagenesis in the mouse

artículo científico publicado en 2004

Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders

artículo científico publicado en 2004

Tuning the period of the mammalian circadian clock: additive and independent effects of CK1εTau and Fbxl3Afh mutations on mouse circadian behavior and molecular pacemaking.

artículo científico publicado en 2011

When clocks go bad: neurobehavioural consequences of disrupted circadian timing

artículo científico publicado en 2008

Lista de obras de Patrick M. Nolan

A comparison of physiological and behavioural parameters in C57BL/6J mice undergoing food or water restriction regimes

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice

A twin and molecular genetics study of sleep paralysis and associated factors

Acquisition of a brief behavioral experience in the presence of neuron-specific and D2-CAM/N-CAM-specific antisera

Acquisition of a brief behavioural experience in the rat is inhibited by the brain-specific monoclonal antibody, F3-87-8.

Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

Assessing mouse behaviour throughout the light/dark cycle using automated in-cage analysis tools

Clocks go forward: progress in the molecular genetic analysis of rhythmic behaviour

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

Cognitive assessment of mice strains heterozygous for cell-adhesion genes reveals strain-specific alterations in timing

Defining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse model

Dibutyryl cyclic AMP stimulates expression of ependymin mRNA and the synthesis and release of the protein into the culture medium by neuroblastoma cells (NB2a/d1).

Differential roles for cryptochromes in the mammalian retinal clock

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.

Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features

ENU mutagenesis in the mouse: application to human genetic disease

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.

Early motor deficits in mouse disease models are reliably uncovered using an automated home-cage wheel-running system: a cross-laboratory validation.

Forward genetics identifies a novel sleep mutant with sleep state inertia and REM sleep deficits

Gene-environment interactions differentially affect mouse strain behavioral parameters

Generation of mouse mutants as tools in dissecting the molecular clock

Genetic and molecular analysis of the central and peripheral circadian clockwork of mice

Genetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep

Hippocampal NCAM180 transiently increases sialylation during the acquisition and consolidation of a passive avoidance response in the adult rat.

Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits

Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.

Inducible Knockout of Mouse Zfhx3 Emphasizes Its Key Role in Setting the Pace and Amplitude of the Adult Circadian Clock

Informatics for mutagenesis: the design of mutabase--a distributed data recording system for animal husbandry, mutagenesis, and phenotypic analysis

KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility

Learning-induced change in neural activity during acquisition and consolidation of a passive avoidance response in the rat.

Loss of disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities

Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light

Meta-analysis of transcriptomic datasets identifies genes enriched in the mammalian circadian pacemaker.

Mouse mutagenesis-systematic studies of mammalian gene function

Mutagenesis and behavioral screening for altered circadian activity identifies the mouse mutant, Wheels

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse

Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans

Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland

N-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2.

Novel phenotypes identified by plasma biochemical screening in the mouse

Overexpression of Fto leads to increased food intake and results in obesity

Phenotyping first-generation genome editing mutants: a new standard?

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures

Random mutagenesis screen for dominant behavioral mutations in mice

Reaching and grasping phenotypes in the mouse (Mus musculus): a characterization of inbred strains and mutant lines

Reciprocal interactions between circadian clocks and aging

Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

Replication of Genome-Wide Association Studies (GWAS) loci for sleep in the British G1219 cohort

Running endurance abnormality in mdx mice

Screening for novel ENU-induced rhythm, entrainment and activity mutants.

Sleep-like behavior and 24-h rhythm disruption in the Tc1 mouse model of Down syndrome

Soluble rat brain sialidase does not influence intracellular glycosylation of Golgi sialyltransferase or its constitutive glycoproteins

Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

The Wheels mutation in the mouse causes vascular, hindbrain, and inner ear defects

The Zfhx3-Mediated Axis Regulates Sleep and Interval Timing in Mice

The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis

The guanine nucleotide exchange factor, Spata13, influences social behaviour and nocturnal activity

The role of mutagenesis in defining genes in behaviour

Three novel pigmentation mutants generated by genome-wide random ENU mutagenesis in the mouse

Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders

Tuning the period of the mammalian circadian clock: additive and independent effects of CK1εTau and Fbxl3Afh mutations on mouse circadian behavior and molecular pacemaking.

When clocks go bad: neurobehavioural consequences of disrupted circadian timing