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Lista de obras de Wei Chen

A human snoRNA with microRNA-like functions

artículo científico publicado en 2008

A novel X-linked recessive mental retardation syndrome comprising macrocephaly and ciliary dysfunction is allelic to oral-facial-digital type I syndrome

artículo científico publicado en 2006

A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation

artículo científico publicado en 2012

Altered histone acetylation is associated with age-dependent memory impairment in mice.

artículo científico publicado en 2010

An Integrated Understanding of the Molecular Mechanisms How Adipose Tissue Metabolism Affects Long-Term Body Weight Maintenance

artículo científico publicado en 2018

Array CGH identifies reciprocal 16p13.1 duplications and deletions that predispose to autism and/or mental retardation

artículo científico publicado en 2007

Breakpoint analysis of balanced chromosome rearrangements by next-generation paired-end sequencing

artículo científico publicado en 2009

CASB: a concanavalin A-based sample barcoding strategy for single-cell sequencing

artículo científico publicado en 2021

CGHPRO -- a comprehensive data analysis tool for array CGH.

artículo científico publicado en 2005

CIGAR-seq, a CRISPR/Cas-based method for unbiased screening of novel mRNA modification regulators

scientific article published on 01 November 2020

Characterization of a 5.3 Mb deletion in 15q14 by comparative genomic hybridization using a whole genome "tiling path" BAC array in a girl with heart defect, cleft palate, and developmental delay.

artículo científico publicado en 2007

Characterization of interstitial Xp duplications in two families by tiling path array CGH

Comparative analysis of transposable element vector systems in human cells

artículo científico publicado en 2010

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

artículo científico publicado en 2008

Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells

artículo científico publicado en 2011

Comprehensive survey of human brain microRNA by deep sequencing

artículo científico publicado en 2010

De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics

artículo científico publicado en 2011

Deciphering the porcine intestinal microRNA transcriptome

artículo científico publicado en 2010

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

artículo científico publicado en 2011

Discovering microRNAs from deep sequencing data using miRDeep

artículo científico publicado en 2008

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.

artículo científico publicado en 2012

Estimating accuracy of RNA-Seq and microarrays with proteomics

artículo científico publicado en 2009

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques

artículo científico publicado en 2012

Full-length transcriptome reconstruction reveals a large diversity of RNA and protein isoforms in rat hippocampus

scientific article published on 01 November 2019

Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells.

artículo científico publicado en 2012

Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel

artículo científico publicado en 2010

Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation.

artículo científico publicado en 2016

Global quantification of mammalian gene expression control

artículo científico publicado en 2011

High frequency of submicroscopic genomic aberrations detected by tiling path array comparative genome hybridisation in patients with isolated congenital heart disease.

artículo científico publicado en 2008

Homozygosity mapping in consanguineous families reveals extreme heterogeneity of non-syndromic autosomal recessive mental retardation and identifies 8 novel gene loci.

artículo científico publicado en 2006

Hybridisation-based resequencing of 17 X-linked intellectual disability genes in 135 patients reveals novel mutations in ATRX, SLC6A8 and PQBP1.

artículo científico publicado en 2011

Impact of low copy repeats on the generation of balanced and unbalanced chromosomal aberrations in mental retardation.

artículo científico publicado en 2006

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

scientific article published on 17 February 2020

Integrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells

artículo científico publicado en 2012

Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT

artículo científico publicado en 2020

Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq

artículo científico publicado en 2010

Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression

artículo científico publicado en 2009

Mapping translocation breakpoints by next-generation sequencing

artículo científico publicado en 2008

MicroRNA expression and regulation in human, chimpanzee, and macaque brains

artículo científico publicado en 2011

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain

artículo científico publicado en 2010

MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates

artículo científico publicado en 2011

Mutation screening of brain-expressed X-chromosomal miRNA genes in 464 patients with nonsyndromic X-linked mental retardation

artículo científico publicado en 2006

Next generation sequencing in a family with autosomal recessive Kahrizi syndrome (OMIM 612713) reveals a homozygous frameshift mutation in SRD5A3

artículo científico publicado en 2010

Pan-tissue analysis of allelic alternative polyadenylation suggests widespread functional regulation

artículo científico publicado en 2020

Pervasive isoform-specific translational regulation via alternative transcription start sites in mammals.

artículo científico publicado en 2016

Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells

artículo científico publicado en 2012

Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains

artículo científico publicado en 2012

Retargeting transposon insertions by the adeno-associated virus Rep protein.

artículo científico publicado en 2012

ST3GAL3 mutations impair the development of higher cognitive functions.

artículo científico publicado en 2011

Sequence features associated with microRNA strand selection in humans and flies

artículo científico publicado en 2009

The IκB kinase complex is a regulator of mRNA stability

scientific article published on 22 November 2018

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant

scientific article published on 04 December 2019

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.

artículo científico publicado en 2010

Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP.

artículo científico publicado en 2010

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

artículo científico publicado en 2011

Widespread expression of piRNA-like molecules in somatic tissues

artículo científico publicado en 2011

Widespread splicing changes in human brain development and aging

artículo científico publicado en 2013

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

artículo científico publicado en 2011