Lista de obras - Kristaps Jaudzems - Dominio Público Uruguay

2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity

artículo científico publicado en 2018

A novel zinc-binding fold in the helicase interaction domain of the Bacillus subtilis DnaI helicase loader

artículo científico publicado en 2009

A spidroin-derived solubility tag enables controlled aggregation of a designed amyloid protein

artículo científico publicado en 2018

Azole-based non-peptidomimetic plasmepsin inhibitors

artículo científico publicado en 2018

Biomimetic composites with enhanced toughening using silk-inspired triblock proteins and aligned nanocellulose reinforcements

artículo científico publicado en 2019

Carbonic anhydrase generates CO2 and H+ that drive spider silk formation via opposite effects on the terminal domains

artículo científico publicado en 2014

Comparison of NMR and crystal structures for the proteins TM1112 and TM1367

artículo científico publicado en 2010

Comparison of NMR and crystal structures highlights conformational isomerism in protein active sites

artículo científico publicado en 2010

Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins.

artículo científico publicado en 2016

DNP NMR of Biomolecular Assemblies

Degree of Biomimicry of Artificial Spider Silk Spinning Assessed by NMR Spectroscopy

artículo científico publicado en 2017

Degree of Biomimicry of Artificial Spider Silk Spinning Assessed by NMR Spectroscopy

Discovery and structure-activity relationship studies of irreversible benzisothiazolinone-based inhibitors against Staphylococcus aureus sortase A transpeptidase

artículo científico publicado en 2014

Diversified Structural Basis of a Conserved Molecular Mechanism for pH-Dependent Dimerization in Spider Silk N-Terminal Domains

artículo científico publicado en 2015

Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies

artículo científico publicado en 2019

Dynamic Nuclear Polarization-Enhanced Biomolecular NMR Spectroscopy at High Magnetic Field with Fast Magic-Angle Spinning

artículo científico publicado en 2018

Efficient protein production inspired by how spiders make silk

artículo científico publicado en 2017

Exploiting Structural Dynamics To Design Open-Flap Inhibitors of Malarial Aspartic Proteases

scientific article published on 16 May 2019

Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV

artículo científico publicado en 2016

High-resolution proton-detected NMR of proteins at very fast MAS.

artículo científico publicado en 2015

Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism

artículo científico publicado en 2009

Is protein deuteration beneficial for proton detected solid-state NMR at and above 100 kHz magic-angle spinning?

artículo científico publicado en 2017

J-UNIO protocol used for NMR structure determination of the 206-residue protein NP_346487.1 from Streptococcus pneumoniae TIGR4.

artículo científico publicado en 2014

Lunasin is a redox sensitive intrinsically disordered peptide with two transiently populated α-helical regions

artículo científico publicado en 2016

N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors ⬇️

artículo científico publicado en 2018

NMR Spectroscopic Assignment of Backbone and Side-Chain Protons in Fully Protonated Proteins: Microcrystals, Sedimented Assemblies, and Amyloid Fibrils

artículo científico publicado en 2016

NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH 6.5

artículo científico publicado en 2010

NMR structure of the protein NP_247299.1: comparison with the crystal structure

artículo científico publicado en 2010

O-tert-Butyltyrosine, an NMR tag for high-molecular-weight systems and measurements of submicromolar ligand binding affinities.

artículo científico publicado en 2015

Out-and-back 13C-13C scalar transfers in protein resonance assignment by proton-detected solid-state NMR under ultra-fast MAS.

artículo científico publicado en 2013

Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D

artículo científico publicado en 2018

Plasmepsin Inhibitory Activity and Structure-Guided Optimization of a Potent Hydroxyethylamine-Based Antimalarial Hit

artículo científico publicado en 2014

Rapid proton-detected NMR assignment for proteins with fast magic angle spinning

artículo científico publicado en 2014

Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation

artículo científico publicado en 2014

Solution NMR structure of Borrelia burgdorferi outer surface lipoprotein BBP28, a member of the mlp protein family

scientific article published on 18 September 2020

Structural and Functional Analysis of BBA03, Borrelia burgdorferi Competitive Advantage Promoting Outer Surface Lipoprotein

artículo científico publicado en 2020

Structural and functional analysis of BB0689 from Borrelia burgdorferi, a member of the bacterial CAP superfamily

artículo científico publicado en 2015

Structural basis for 5'-end-specific recognition of single-stranded DNA by the R3H domain from human Sμbp-2

artículo científico publicado en 2012

Structural characterization of CspZ, a complement regulator factor H and FHL-1 binding protein from Borrelia burgdorferi

artículo científico publicado en 2014

Structural studies of amyloid-β peptides: Unlocking the mechanism of aggregation and the associated toxicity.

artículo científico publicado en 2017

Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages

artículo científico publicado en 2016

Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

artículo científico publicado en 2016

Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors

artículo científico publicado en 2015

Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization

artículo científico publicado en 2019

Transmissible amyloid

artículo científico publicado en 2016

pH-dependent dimerization of spider silk N-terminal domain requires relocation of a wedged tryptophan side chain

artículo científico publicado en 2012

Lista de obras de Kristaps Jaudzems

2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity

A novel zinc-binding fold in the helicase interaction domain of the Bacillus subtilis DnaI helicase loader

A spidroin-derived solubility tag enables controlled aggregation of a designed amyloid protein

Azole-based non-peptidomimetic plasmepsin inhibitors

Biomimetic composites with enhanced toughening using silk-inspired triblock proteins and aligned nanocellulose reinforcements

Carbonic anhydrase generates CO2 and H+ that drive spider silk formation via opposite effects on the terminal domains

Comparison of NMR and crystal structures for the proteins TM1112 and TM1367

Comparison of NMR and crystal structures highlights conformational isomerism in protein active sites

Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins.

DNP NMR of Biomolecular Assemblies

Degree of Biomimicry of Artificial Spider Silk Spinning Assessed by NMR Spectroscopy

Degree of Biomimicry of Artificial Spider Silk Spinning Assessed by NMR Spectroscopy

Discovery and structure-activity relationship studies of irreversible benzisothiazolinone-based inhibitors against Staphylococcus aureus sortase A transpeptidase

Diversified Structural Basis of a Conserved Molecular Mechanism for pH-Dependent Dimerization in Spider Silk N-Terminal Domains

Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies

Dynamic Nuclear Polarization-Enhanced Biomolecular NMR Spectroscopy at High Magnetic Field with Fast Magic-Angle Spinning

Efficient protein production inspired by how spiders make silk

Exploiting Structural Dynamics To Design Open-Flap Inhibitors of Malarial Aspartic Proteases

Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV

High-resolution proton-detected NMR of proteins at very fast MAS.

Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism

Is protein deuteration beneficial for proton detected solid-state NMR at and above 100 kHz magic-angle spinning?

J-UNIO protocol used for NMR structure determination of the 206-residue protein NP_346487.1 from Streptococcus pneumoniae TIGR4.

Lunasin is a redox sensitive intrinsically disordered peptide with two transiently populated α-helical regions

N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors ⬇️

NMR Spectroscopic Assignment of Backbone and Side-Chain Protons in Fully Protonated Proteins: Microcrystals, Sedimented Assemblies, and Amyloid Fibrils

NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH 6.5

NMR structure of the protein NP_247299.1: comparison with the crystal structure

O-tert-Butyltyrosine, an NMR tag for high-molecular-weight systems and measurements of submicromolar ligand binding affinities.

Out-and-back 13C-13C scalar transfers in protein resonance assignment by proton-detected solid-state NMR under ultra-fast MAS.

Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D

Plasmepsin Inhibitory Activity and Structure-Guided Optimization of a Potent Hydroxyethylamine-Based Antimalarial Hit

Rapid proton-detected NMR assignment for proteins with fast magic angle spinning

Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation

Solution NMR structure of Borrelia burgdorferi outer surface lipoprotein BBP28, a member of the mlp protein family

Structural and Functional Analysis of BBA03, Borrelia burgdorferi Competitive Advantage Promoting Outer Surface Lipoprotein

Structural and functional analysis of BB0689 from Borrelia burgdorferi, a member of the bacterial CAP superfamily

Structural basis for 5'-end-specific recognition of single-stranded DNA by the R3H domain from human Sμbp-2

Structural characterization of CspZ, a complement regulator factor H and FHL-1 binding protein from Borrelia burgdorferi

Structural studies of amyloid-β peptides: Unlocking the mechanism of aggregation and the associated toxicity.

Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages

Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors

Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization

Transmissible amyloid

pH-dependent dimerization of spider silk N-terminal domain requires relocation of a wedged tryptophan side chain