Lista de obras - Genta Ito - Dominio Público Uruguay

Analysis of the adrenal gland is useful for evaluating pathology of the peripheral autonomic nervous system in lewy body disease

artículo científico publicado en 2007

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

artículo científico publicado en 2007

Differential effects of familial parkinson mutations in LRRK2 revealed by a systematic analysis of autophosphorylation

artículo científico publicado en 2013

Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor

artículo científico publicado en 2015

Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease

artículo científico publicado en 2007

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease

artículo científico publicado en 2007

Identification of the autophosphorylation sites of LRRK2.

artículo científico publicado en 2009

LRRK2 in Parkinson's disease and dementia with Lewy bodies

artículo científico publicado en 2006

Lack of correlation between the kinase activity of LRRK2 harboring kinase-modifying mutations and its phosphorylation at Ser910, 935, and Ser955.

artículo científico publicado en 2014

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

artículo científico publicado en 2008

Lewy body pathology involves cutaneous nerves

artículo científico publicado en 2008

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

scientific article published on 29 July 2016

Phosphorylation of α-synuclein protein at Ser-129 reduces neuronal dysfunction by lowering its membrane binding property in Caenorhabditis elegans

artículo científico publicado en 2012

Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form

artículo científico publicado en 2012

Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1.

artículo científico publicado en 2005

Structural Characterization of LRRK2 Inhibitors

artículo científico publicado en 2015

Lista de obras de Genta Ito

Analysis of the adrenal gland is useful for evaluating pathology of the peripheral autonomic nervous system in lewy body disease

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

Differential effects of familial parkinson mutations in LRRK2 revealed by a systematic analysis of autophosphorylation

Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor

Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease

Identification of the autophosphorylation sites of LRRK2.

LRRK2 in Parkinson's disease and dementia with Lewy bodies

Lack of correlation between the kinase activity of LRRK2 harboring kinase-modifying mutations and its phosphorylation at Ser910, 935, and Ser955.

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

Lewy body pathology involves cutaneous nerves

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

Phosphorylation of α-synuclein protein at Ser-129 reduces neuronal dysfunction by lowering its membrane binding property in Caenorhabditis elegans

Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form

Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1.

Structural Characterization of LRRK2 Inhibitors