Lista de obras - Gemma Triola - Dominio Público Uruguay

A Highly Efficient Strategy for Modification of Proteins at the C Terminus

artículo científico publicado en 2010

ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds

artículo científico publicado en 2008

Activity-Based Imaging of Acid Ceramidase in Living Cells

scientific article published on 02 May 2019

Analogs of the dihydroceramide desaturase inhibitor GT11 modified at the amide function: synthesis and biological activities

artículo científico publicado en 2005

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

artículo científico publicado en 2011

Azide-tagged sphingolipids for the proteome-wide identification of C16-ceramide-binding proteins

artículo científico publicado en 2018

Bioorthogonal chemistry for site-specific labeling and surface immobilization of proteins

artículo científico publicado en 2011

Chemical biology of lipidated proteins

artículo científico publicado en 2012

Chemical-biological exploration of the limits of the Ras de- and repalmitoylating machinery

artículo científico publicado en 2012

Direct immobilization of oxyamine-modified proteins from cell lysates.

artículo científico publicado en 2012

Dissociation of the K-Ras4B/PDEδ Complex upon Contact with Lipid Membranes: Membrane Delivery Instead of Extraction

article

Efficient microwave-assisted synthesis of unsymmetrical disulfides

artículo científico publicado en 2010

Gibbs energy determinants of lipoprotein insertion into lipid membranes: the case study of Ras proteins

artículo científico publicado en 2013

High Affinity Immobilization of Proteins Using the CrAsH/TC Tag.

artículo científico publicado en 2016

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

artículo científico publicado en 2011

Identification of benzo[cd]indol-2(1H)-ones as novel Atg4B inhibitors via a structure-based virtual screening and a novel AlphaScreen assay

artículo científico publicado en 2019

Influence of the lipid anchor motif of N-ras on the interaction with lipid membranes: a surface plasmon resonance study

artículo científico publicado en 2010

Influence of the lipidation motif on the partitioning and association of N-Ras in model membrane subdomains

artículo científico publicado en 2009

Inhibition of Rab Prenylation

article published in 2011

Interaction of the human N-Ras protein with lipid raft model membranes of varying degrees of complexity

article

Membrane-mediated induction and sorting of K-Ras microdomain signaling platforms

artículo científico publicado en 2010

N-Ras forms dimers at POPC membranes

artículo científico publicado en 2012

One-Pot Dual-Labeling of a Protein by Two Chemoselective Reactions

scientific article published on 14 July 2011

Racemization-free synthesis of S-alkylated cysteines via thiol-ene reaction

artículo científico publicado en 2008

Revealing conformational substates of lipidated N-Ras protein by pressure modulation

artículo científico publicado en 2011

Rotational and Translational Dynamics of Ras Proteins upon Binding to Model Membrane Systems

article

Semisynthetic lipidated LC3 protein mediates membrane fusion

artículo científico publicado en 2013

Site-specific, reversible and fluorescent immobilization of proteins on CrAsH-modified surfaces for microarray analytics

artículo científico publicado en 2014

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

artículo científico publicado en 2013

Solid-Phase Synthesis of Lipidated Ras Peptides Employing the Ellman Sulfonamide Linker

Specificity of Lipoprotein Chaperones for the Characteristic Lipidated Structural Motifs of their Cognate Lipoproteins

scholarly article by Tom Mejuch published in October 2015

Specificity of the dihydroceramide desaturase inhibitor N-[(1R,2S)-2-hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl]octanamide (GT11) in primary cultured cerebellar neurons.

artículo científico publicado en 2004

Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEδ prenyl binding site

artículo científico publicado en 2014

Synthesis of cyclopropene analogues of ceramide and their effect on dihydroceramide desaturase

artículo científico publicado en 2003

Synthesis of lipidated peptides

artículo científico publicado en 2013

Synthesis of the Rheb and K-Ras4B GTPases

The Lipid Modifications of Ras that Sense Membrane Environments and Induce Local Enrichment

article

The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction

article

Visualizing association of lipidated signaling proteins in heterogeneous membranes--partitioning into subdomains, lipid sorting, interfacial adsorption, and protein association

artículo científico publicado en 2009

cis- versus trans-ceramides: effects of the double bond on conformation and H-bonding interactions

artículo científico publicado en 2009

Lista de obras de Gemma Triola

A Highly Efficient Strategy for Modification of Proteins at the C Terminus

ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds

Activity-Based Imaging of Acid Ceramidase in Living Cells

Analogs of the dihydroceramide desaturase inhibitor GT11 modified at the amide function: synthesis and biological activities

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

Azide-tagged sphingolipids for the proteome-wide identification of C16-ceramide-binding proteins

Bioorthogonal chemistry for site-specific labeling and surface immobilization of proteins

Chemical biology of lipidated proteins

Chemical-biological exploration of the limits of the Ras de- and repalmitoylating machinery

Direct immobilization of oxyamine-modified proteins from cell lysates.

Dissociation of the K-Ras4B/PDEδ Complex upon Contact with Lipid Membranes: Membrane Delivery Instead of Extraction

Efficient microwave-assisted synthesis of unsymmetrical disulfides

Gibbs energy determinants of lipoprotein insertion into lipid membranes: the case study of Ras proteins

High Affinity Immobilization of Proteins Using the CrAsH/TC Tag.

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

Identification of benzo[cd]indol-2(1H)-ones as novel Atg4B inhibitors via a structure-based virtual screening and a novel AlphaScreen assay

Influence of the lipid anchor motif of N-ras on the interaction with lipid membranes: a surface plasmon resonance study

Influence of the lipidation motif on the partitioning and association of N-Ras in model membrane subdomains

Inhibition of Rab Prenylation

Interaction of the human N-Ras protein with lipid raft model membranes of varying degrees of complexity

Membrane-mediated induction and sorting of K-Ras microdomain signaling platforms

N-Ras forms dimers at POPC membranes

One-Pot Dual-Labeling of a Protein by Two Chemoselective Reactions

Racemization-free synthesis of S-alkylated cysteines via thiol-ene reaction

Revealing conformational substates of lipidated N-Ras protein by pressure modulation

Rotational and Translational Dynamics of Ras Proteins upon Binding to Model Membrane Systems

Semisynthetic lipidated LC3 protein mediates membrane fusion

Site-specific, reversible and fluorescent immobilization of proteins on CrAsH-modified surfaces for microarray analytics

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

Solid-Phase Synthesis of Lipidated Ras Peptides Employing the Ellman Sulfonamide Linker

Specificity of Lipoprotein Chaperones for the Characteristic Lipidated Structural Motifs of their Cognate Lipoproteins

Specificity of the dihydroceramide desaturase inhibitor N-[(1R,2S)-2-hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl]octanamide (GT11) in primary cultured cerebellar neurons.

Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEδ prenyl binding site

Synthesis of cyclopropene analogues of ceramide and their effect on dihydroceramide desaturase

Synthesis of lipidated peptides

Synthesis of the Rheb and K-Ras4B GTPases

The Lipid Modifications of Ras that Sense Membrane Environments and Induce Local Enrichment

The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction

Visualizing association of lipidated signaling proteins in heterogeneous membranes--partitioning into subdomains, lipid sorting, interfacial adsorption, and protein association

cis- versus trans-ceramides: effects of the double bond on conformation and H-bonding interactions