Lista de obras - Winfried Barchet - Dominio Público Uruguay

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.

artículo científico publicado en 2015

A human in vitro whole blood assay to predict the systemic cytokine response to therapeutic oligonucleotides including siRNA

artículo científico publicado en 2013

Accessing the therapeutic potential of immunostimulatory nucleic acids

scientific article published on 30 July 2008

Accumulation of ALDH1-positive cells after neoadjuvant chemotherapy predicts treatment resistance and prognosticates poor outcome in ovarian cancer.

artículo científico publicado en 2015

Activation of Endothelial Toll-Like Receptor 3 Impairs Endothelial Function

Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus.

artículo científico publicado en 2009

Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection

artículo científico publicado en 1998

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

artículo científico publicado en 2014

Approaching the RNA ligand for RIG-I?

artículo científico publicado en 2009

Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation.

artículo científico publicado en 2009

Beyond double-stranded RNA-type I IFN induction by 3pRNA and other viral nucleic acids

artículo científico publicado en 2007

Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA.

artículo científico publicado en 2014

Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation.

artículo científico publicado en 2005

Cutting Edge: Murine Vascular Endothelium Activates and Induces the Generation of Allogeneic CD4+25+Foxp3+ Regulatory T Cells

scientific article published on 01 November 2005

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

artículo científico publicado en 2013

Delivery with polycations extends the immunostimulant Ribomunyl® into a potent antiviral Toll-like receptor 7/8 agonist

article published in 2011

Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways

artículo científico publicado en 2005

Development and function of murine B220+CD11c+NK1.1+ cells identify them as a subset of NK cells

artículo científico publicado en 2007

Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo

artículo científico publicado en 2000

Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice

artículo científico publicado en 2011

Donor cell persistence and activation-induced unresponsiveness of peripheral CD8+ T cells

artículo científico publicado en 2000

Endothelial RIG-I activation impairs endothelial function

artículo científico publicado en 2012

Enhanced skin expression of melanoma differentiation-associated gene 5 (MDA5) in dermatomyositis and related autoimmune diseases.

artículo científico publicado en 2011

Exonuclease TREX1 also Has a Sweet Tooth.

artículo científico publicado en 2015

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

artículo científico publicado en 2003

Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA.

artículo científico publicado en 2009

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

artículo científico publicado en 2013

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

artículo científico publicado en 2004

Human plasmacytoid dendritic cells support Th17 cell effector function in response to TLR7 ligation

artículo científico publicado en 2009

Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells.

artículo científico publicado en 2011

MDA-5 activation by cytoplasmic double-stranded RNA impairs endothelial function and aggravates atherosclerosis

artículo científico publicado en 2016

Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist

scientific article published on 11 September 2013

Monocyte-Mediated Inhibition of TLR9-Dependent IFN- Induction in Plasmacytoid Dendritic Cells Questions Bacterial DNA as the Active Ingredient of Bacterial Lysates

artículo científico publicado en 2010

Nitrosative stress: a hallmark of the junctional inflammation in cutaneous lupus erythematosus

Nucleic acid adjuvants: toward an educated vaccine

artículo científico

Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing

artículo científico publicado en 2013

PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons

artículo científico publicado en 2006

Paracoccus yeeii sp. nov. (formerly CDC group EO-2), a novel bacterial species associated with human infection

artículo científico publicado en 2003

Plasmacytoid dendritic cells--virus experts of innate immunity

artículo científico publicado en 2005

Plasmacytoid dendritic cells: in search of their niche in immune responses

artículo científico publicado en 2005

Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease

artículo científico publicado en 2010

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

artículo científico publicado en 2012

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells

artículo científico publicado en 2013

RNA recognition via TLR7 and TLR8.

artículo científico publicado en 2008

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

artículo científico publicado en 2009

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

artículo científico publicado en 2009

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

artículo científico publicado en 2011

Selective and direct activation of human neutrophils but not eosinophils by Toll-like receptor 8.

artículo científico publicado en 2009

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

artículo científico publicado en 2015

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

artículo científico publicado en 2013

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

article

Targeted activation of RNA helicase retinoic acid-inducible gene-I induces proimmunogenic apoptosis of human ovarian cancer cells

artículo científico publicado en 2010

Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

artículo científico publicado en 2002

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections

artículo científico publicado en 2015

The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM

artículo científico publicado en 2005

Translating nucleic acid-sensing pathways into therapies

artículo científico

Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo

artículo científico publicado en 2002

cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites

artículo científico publicado en 2016

Lista de obras de Winfried Barchet

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.

A human in vitro whole blood assay to predict the systemic cytokine response to therapeutic oligonucleotides including siRNA

Accessing the therapeutic potential of immunostimulatory nucleic acids

Accumulation of ALDH1-positive cells after neoadjuvant chemotherapy predicts treatment resistance and prognosticates poor outcome in ovarian cancer.

Activation of Endothelial Toll-Like Receptor 3 Impairs Endothelial Function

Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus.

Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

Approaching the RNA ligand for RIG-I?

Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation.

Beyond double-stranded RNA-type I IFN induction by 3pRNA and other viral nucleic acids

Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA.

Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation.

Cutting Edge: Murine Vascular Endothelium Activates and Induces the Generation of Allogeneic CD4+25+Foxp3+ Regulatory T Cells

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Delivery with polycations extends the immunostimulant Ribomunyl® into a potent antiviral Toll-like receptor 7/8 agonist

Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways

Development and function of murine B220+CD11c+NK1.1+ cells identify them as a subset of NK cells

Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo

Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice

Donor cell persistence and activation-induced unresponsiveness of peripheral CD8+ T cells

Endothelial RIG-I activation impairs endothelial function

Enhanced skin expression of melanoma differentiation-associated gene 5 (MDA5) in dermatomyositis and related autoimmune diseases.

Exonuclease TREX1 also Has a Sweet Tooth.

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA.

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

Human plasmacytoid dendritic cells support Th17 cell effector function in response to TLR7 ligation

Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells.

MDA-5 activation by cytoplasmic double-stranded RNA impairs endothelial function and aggravates atherosclerosis

Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist

Monocyte-Mediated Inhibition of TLR9-Dependent IFN- Induction in Plasmacytoid Dendritic Cells Questions Bacterial DNA as the Active Ingredient of Bacterial Lysates

Nitrosative stress: a hallmark of the junctional inflammation in cutaneous lupus erythematosus

Nucleic acid adjuvants: toward an educated vaccine

Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing

PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons

Paracoccus yeeii sp. nov. (formerly CDC group EO-2), a novel bacterial species associated with human infection

Plasmacytoid dendritic cells--virus experts of innate immunity

Plasmacytoid dendritic cells: in search of their niche in immune responses

Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells

RNA recognition via TLR7 and TLR8.

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

Selective and direct activation of human neutrophils but not eosinophils by Toll-like receptor 8.

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

Targeted activation of RNA helicase retinoic acid-inducible gene-I induces proimmunogenic apoptosis of human ovarian cancer cells

Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections

The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM

Translating nucleic acid-sensing pathways into therapies

Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo

cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites