Lista de obras - Christopher J. Lengner - Dominio Público Uruguay

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

artículo científico publicado en 2008

A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

artículo científico publicado en 2014

Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton

artículo científico publicado en 2002

An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis.

artículo científico publicado en 2003

Analysis of in vivo gene expression using epitope-tagged proteins

artículo científico publicado en 2004

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

artículo científico publicado en 2005

Chromatin immunoprecipitation

scientific article published on 01 January 2004

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function

artículo científico publicado en 2015

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

artículo científico publicado en 2010

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

Direct cell reprogramming is a stochastic process amenable to acceleration

artículo científico publicado en 2009

Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency

artículo científico publicado en 2008

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation

scientific article published on 01 November 2019

Dll1<sup>+</sup> quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway

artículo científico publicado en 2021

Electromagnetic fields mediate efficient cell reprogramming into a pluripotent state

artículo científico publicado en 2014

Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Dyskeratosis Congenita

artículo científico publicado en 2016

Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain

artículo científico publicado en 2008

Functional integration of dopaminergic neurons directly converted from mouse fibroblasts

artículo científico publicado en 2011

GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells

artículo científico publicado en 2022

Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts

artículo científico publicado en 2016

Homogeneous generation of iDA neurons with high similarity to bona fide DA neurons using a drug inducible system

artículo científico publicado en 2015

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

artículo científico publicado en 2010

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

scientific article published on 01 January 2004

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

artículo científico publicado en 2004

In situ immunofluorescence analysis: immunofluorescence microscopy

scientific article published on 01 January 2004

LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3

artículo científico publicado en 2023

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

artículo científico publicado en 2016

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

scholarly article by Jacob Hanna et al published August 2015 in Cell Stem Cell

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

scholarly article by Jacob Hanna et al published May 2015 in Cell Stem Cell

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

Metastable pluripotent states in NOD-mouse-derived ESCs

artículo científico publicado en 2009

Mouse Label-Retaining Cells Are Molecularly and Functionally Distinct From Reserve Intestinal Stem Cells

artículo científico publicado en 2016

Msi RNA-binding proteins control reserve intestinal stem cell quiescence.

artículo científico publicado en 2016

Multiphasic and Dynamic Changes in Alternative Splicing during Induction of Pluripotency Are Coordinated by Numerous RNA-Binding Proteins

artículo científico publicado en 2016

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

artículo científico publicado en 2014

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

artículo científico publicado en 2014

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

artículo científico publicado en 2010

Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program

artículo científico publicado en 2015

Networks and hubs for the transcriptional control of osteoblastogenesis.

artículo científico publicado en 2006

Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation

scientific journal article

Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis.

artículo científico publicado en 2016

Oct4 expression is not required for mouse somatic stem cell self-renewal

artículo científico publicado en 2007

Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish

artículo científico publicado en 2013

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

artículo científico publicado en 2006

Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22.

artículo científico publicado en 2015

Primary mouse embryonic fibroblasts: A model of mesenchymal cartilage formation

article

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

artículo científico publicado en 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

scientific article published on 01 January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

artículo científico publicado en 2004

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

artículo científico publicado en 2004

Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

artículo científico publicado en 2011

Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

artículo científico publicado en 2011

Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation

artículo científico publicado en 2011

Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation

artículo científico publicado en 2006

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

artículo científico publicado en 2008

Single-cell analysis of proxy reporter allele-marked epithelial cells establishes intestinal stem cell hierarchy

artículo científico publicado en 2014

The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins

artículo científico publicado en 2015

Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.

artículo científico publicado en 2015

Transgenic mice with defined combinations of drug-inducible reprogramming factors

artículo científico publicado en 2009

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium

artículo científico publicado en 2016

iPS cell technology in regenerative medicine

artículo científico publicado en 2010

Lista de obras de Christopher J. Lengner

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton

An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis.

Analysis of in vivo gene expression using epitope-tagged proteins

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

Chromatin immunoprecipitation

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

Direct cell reprogramming is a stochastic process amenable to acceleration

Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation

Dll1<sup>+</sup> quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway

Electromagnetic fields mediate efficient cell reprogramming into a pluripotent state

Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Dyskeratosis Congenita

Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain

Functional integration of dopaminergic neurons directly converted from mouse fibroblasts

GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells

Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts

Homogeneous generation of iDA neurons with high similarity to bona fide DA neurons using a drug inducible system

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

In situ immunofluorescence analysis: immunofluorescence microscopy

LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

Metastable pluripotent states in NOD-mouse-derived ESCs

Mouse Label-Retaining Cells Are Molecularly and Functionally Distinct From Reserve Intestinal Stem Cells

Msi RNA-binding proteins control reserve intestinal stem cell quiescence.

Multiphasic and Dynamic Changes in Alternative Splicing during Induction of Pluripotency Are Coordinated by Numerous RNA-Binding Proteins

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program

Networks and hubs for the transcriptional control of osteoblastogenesis.

Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation

Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis.

Oct4 expression is not required for mouse somatic stem cell self-renewal

Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22.

Primary mouse embryonic fibroblasts: A model of mesenchymal cartilage formation

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation

Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

Single-cell analysis of proxy reporter allele-marked epithelial cells establishes intestinal stem cell hierarchy

The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins

Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.

Transgenic mice with defined combinations of drug-inducible reprogramming factors

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium

iPS cell technology in regenerative medicine