Lista de obras - Françoise Clerget-Darpoux

A gene for Meckel syndrome maps to chromosome 11q13.

artículo científico publicado en 1998

A new methodology for analysis of HLA-associated diseases?

artículo científico publicado en 1983

A systematic study of oligodendrocyte growth factors as candidates for genetic susceptibility to MS

artículo científico publicado en 1998

APOE promoter polymorphisms do not confer independent risk for Alzheimer's disease in a French population.

artículo científico publicado en 2000

About the use of APOE in Alzheimer's disease studies.

artículo científico publicado en 1998

Absence of the amyloid precursor protein gene mutation (APP717: Val->Ile) in 85 cases of early onset Alzheimer's disease.

artículo científico publicado en 1993

Allele variations in the OCA2 gene (pink-eyed-dilution locus) are associated with genetic susceptibility to melanoma

article

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

artículo científico publicado en 1996

An exclusion map covering the whole genome: a new challenge for genetic epidemiologists?

artículo científico publicado en 1993

An ordered subset approach to including covariates in the transmission disequilibrium test

artículo científico publicado en 2007

Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex

artículo científico publicado en 1997

Apolipoprotein E epsilon4 allele and familial aggregation of Alzheimer disease.

artículo científico publicado en 1998

Apolipoprotein E gene in frontotemporal dementia: an association study and meta-analysis

article

Application of the lod score method to detection of linkage between HLA and juvenile insulin-dependent diabetes.

artículo científico publicado en 1980

Are Linkage Analysis and the Collection of Family Data Dead? Prospects for Family Studies in the Age of Genome-Wide Association

article

Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?

scientific article published on 13 December 2006

Assessing the effect of multiple linkage tests in complex diseases.

artículo científico publicado en 1990

Association between a genetic trait and a marker: Discrimination between epistasis and gametic disequilibrium

scientific article published on 01 January 1985

Association between the extended tau haplotype and frontotemporal dementia

artículo científico publicado en 2002

Association in Multifactorial Traits: How to Deal with Rare Observations?

artículo científico publicado en 2004

Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA

artículo científico publicado en 2011

Bias of the estimated recombination fraction and lod score due to an association between a disease gene and a marker gene.

artículo científico publicado en 1982

Candidate gene region 2q33 in European families with coeliac disease

artículo científico publicado en 2004

Caution in the interpretation of MLS

artículo científico publicado en 1997

Chromosome 17q22–q24 and multiple sclerosis genetic susceptibility

article

Chromosome 21 scan in Down syndrome reveals DSCAM as a predisposing locus in Hirschsprung disease

artículo científico publicado en 2013

Comparing the power of linkage detection by the transmission disequilibrium test and the identity-by-descent test

article

Comparison of family based haplotype methods using intragenic SNPs in candidate genes

article

Conclusions of segregation analysis for family data generated under two-locus models.

artículo científico publicado en 1993

Consanguinity and the sib-pair method: an approach using identity by descent between and within individuals.

artículo científico publicado en 1996

Cytokines in genetic susceptibility to multiple sclerosis: a candidate gene approach. French Multiple Sclerosis Genetics Group.

artículo científico publicado en 2000

De novo presenilin 1 mutations are rare in clinically sporadic, early onset Alzheimer's disease cases. French Alzheimer's Disease Study Group.

artículo científico publicado en 1998

Detection and modeling of disease susceptibility locus effects: How much can be learned from contrast of populations?

artículo científico publicado en 1999

Detection of susceptibility loci by genome-wide linkage analysis

artículo científico publicado en 2005

Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis

artículo científico publicado en 2011

Discrimination between genetic models for insulin dependent diabetes mellitus

artículo científico publicado en 1986

Discussing gene-gene interaction: warning--translating equations to English may result in jabberwocky

artículo científico publicado en 2007

Développement embryonnaire précoce

artículo científico publicado en 2012

Estimation of the inbreeding coefficient through use of genomic data

artículo científico publicado en 2003

Evidence for Linkage Disequilibrium Between HLA-DRB1 Gene and Multiple Sclerosis

scientific article published in Science

Evidence for apolipoprotein E epsilon 4 association in early-onset Alzheimer's patients with late-onset relatives.

artículo científico publicado en 1995

Excess of maternal HLA-DR3 antigens in HLA DR3,4 positive Type 1 (insulin-dependent) diabetic patients

article

Existence of a genetic risk factor on chromosome 5q in Italian Coeliac Disease families

artículo científico publicado en 2001

Functional variants of POC5 identified in patients with idiopathic scoliosis

artículo científico publicado en 2015

Genealogical and genetic structure.

artículo científico publicado en 1983

Genetic analysis of multiple sclerosis in Europeans: French data

artículo científico publicado en 2003

Genetic interaction of CTLA-4 with HLA-DR15 in multiple sclerosis patients

artículo científico publicado en 2003

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

artículo científico publicado en 2011

Genetic study of transthyretin amyloid neuropathies: carrier risks among French and Portuguese families.

artículo científico publicado en 2003

Genetics of Alzheimer's disease

artículo científico publicado en 1996

Genome search in celiac disease.

artículo científico publicado en 1998

Génétique épidémiologique de la maladie cœliaque

artículo científico publicado en 2005

HLA related genetic risk for coeliac disease.

artículo científico publicado en 2007

HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease.

artículo científico publicado en 2004

HLA-DRB1*15 allele influences the later course of relapsing remitting multiple sclerosis

article

HLA-associated diseases: a new method for performing linkage analysis with other markers than HLA.

artículo científico publicado en 1984

Hereditary retinoblastoma: can balanced insertion entirely explain the differences of expressivity among families?

artículo científico publicado en 1990

Heterogeneity of marker allele frequencies hinders interpretation of linkage analysis: Illustration on chromosome 18 markers ⬇️

artículo científico publicado el 1 de enero de 1997

High risk genotypes for celiac disease

artículo científico publicado en 1994

Homogeneity of asthma genome scan results.

artículo científico publicado en 2001

IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients

artículo científico publicado en 2009

IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations.

artículo científico publicado en 2008

Identifying modifier genes of monogenic disease: strategies and difficulties.

artículo científico publicado en 2008

Impact of parental relationships in maximum lod score affected sib-pair method

artículo científico publicado en 2002

Improved use of SNP information to detect the role of genes.

artículo científico publicado en 2003

Indication of linkage and genetic heterogeneity for asthma and atopy on chromosomes 8p and 12q in 107 French EGEA families.

artículo científico publicado en 2003

Indication of linkage and genetic heterogeneity of asthma according to age at onset on chromosome 7q in 107 French EGEA families.

artículo científico publicado en 2001

Influence of HLA-DRB1 P4 binding pocket electric charge on rheumatoid arthritis (RA) susceptibility.

artículo científico publicado en 2003

Interactive effect of HLA and Gm and genetic heterogeneity tested in 79 rheumatoid arthritis families.

artículo científico publicado en 1991

Interactive effect of two candidate genes in a disease: extension of the marker-association-segregation chi(2) method.

artículo científico publicado en 1994

Intercellular adhesion molecule-1: a protective haplotype against multiple sclerosis.

artículo científico publicado en 2003

Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study

artículo científico publicado en 2003

Investigation of the HLA component involved in rheumatoid arthritis (RA) by using the marker association-segregation chi-square (MASC) method: rejection of the unifying-shared-epitope hypothesis ⬇️

artículo científico publicado el 1 de septiembre de 1993

Is a single mutation at the same locus responsible for all affected cases in a large Alzheimer pedigree (FAD4)?

artículo científico publicado en 1993

Is the saitohin gene involved in neurodegenerative diseases?

artículo científico publicado en 2002

Juvenile insulin-dependent diabetes: a possible susceptibility gene in interaction with HLA

article

Lack of Correlation Between Genotype and Phenotype in Celiac Disease ⬇️

artículo científico publicado el 1 de marzo de 1998

Letter to the Editor: No evidence for association between the EIF2B5 gene and multiple sclerosis in French families

article

Linkage and association study of the CTLA-4 region in coeliac disease for Italian and Tunisian populations.

artículo científico publicado en 1999

Linkage detection by the Affected-Pedigree-Member method: what is really tested?

artículo científico publicado en 1993

Linkage of familial breast cancer to chromosome 17q21 may not be restricted to early-onset disease ⬇️

artículo científico publicado el 1 de junio de 1992

Male and female differential reproductive rate could explain parental transmission asymmetry of mutation origin in Hirschsprung disease.

artículo científico publicado en 2012

Meta and pooled analysis of European coeliac disease data

artículo científico publicado en 2003

Modeling of HLA class II susceptibility to Type I diabetes reveals an effect associated with DPB1

article

Modeling the effect of PTPN22 in rheumatoid arthritis

artículo científico publicado en 2007

Modeling the effect of a genetic factor for a complex trait in a simulated population

artículo científico publicado en 2005

Modeling the effect of susceptibility factors (HLA and PTPN22) in rheumatoid arthritis

artículo científico publicado en 2011

Modeling the role of two susceptibility loci by the MASC method

scientific article published on 01 January 1995

Mutations in KIAA0586 Cause Lethal Ciliopathies Ranging from a Hydrolethalus Phenotype to Short-Rib Polydactyly Syndrome

artículo científico publicado en 2015

New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility

artículo científico publicado en 2005

New disease gene location and high genetic heterogeneity in idiopathic scoliosis.

artículo científico publicado en 2011

No effect of the alpha1-antichymotrypsin A allele in Alzheimer's disease

artículo científico publicado en 1997

No founder effect in three novel Alzheimer's disease families with APP 717 Val-->Ile mutation. Clerget-darpoux. French Alzheimer's Disease Study Group.

artículo científico publicado en 1996

On the choice of linkage statistics

artículo científico publicado en 2007

On the probability of identity states in permutable populations: reply to Cannings.

artículo científico publicado en 1998

Optimization of genome search strategies for homozygosity mapping: influence of marker spacing on power and threshold criteria for identification of candidate regions

artículo científico publicado en 1998

Overview of strategies for complex genetic diseases

artículo científico publicado en 1998

Où en sont les études génétiques de la SEP ?

artículo científico publicado en 2007

POINTER correctly estimates the transmission probabilities under the general transmission model in the case of incomplete selection ⬇️

artículo científico publicado el 1 de diciembre de 1992

Performance of linkage analysis under misclassification error when the genetic model is unknown

article

Performing genetic analysis with irregular traits

scientific article published on 01 January 1992

Phenotype of familial forms of early-onset Alzheimer's disease linked to chromosome 14. Clinical and neuropsychological characteristics of a large group

artículo científico publicado en 1995

Posterior probability of linkage and maximal lod score.

artículo científico publicado en 1995

Power of genome-wide association studies in the presence of interacting loci

artículo científico publicado en 2007

Power of the 2-locus TDT for testing the interaction of two susceptibility genes

artículo científico publicado en 2007

Progeny group size for evaluating natural service bulls using AI reference sires

artículo científico publicado en 1978

Properties of the transmission-disequilibrium test in the presence of inbreeding

article

Reply to Ott and Mérette.

artículo científico publicado en 1993

Revisiting the Polygenic Additive Liability Model through the Example of Diabetes Mellitus.

artículo científico publicado en 2015

Saturation of the 5q31-q33 Candidate Region for Coeliac Disease

artículo científico publicado en 2003

Search for multifactorial disease susceptibility genes in founder populations

artículo científico publicado en 2000

Season of birth and not vitamin D receptor promoter polymorphisms is a risk factor for multiple sclerosis.

artículo científico publicado en 2009

Segregation analysis in Alzheimer disease: no evidence for a major gene ⬇️

artículo científico publicado el 1 de marzo de 1992

Segregation analysis of Alzheimer pedigrees: rare Mendelian dominant mutation(s) explain a minority of early-onset cases. French Alzheimer Collaborative Group.

artículo científico publicado en 1996

Segregation analysis of the Jacobsen data

article

Segregation analysis of two genetic markers in IDDM families under two-locus models

artículo científico publicado en 1989

Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markers

article

Strategies based on marker information for the study of human diseases.

artículo científico publicado en 1992

Strategy for Detecting Susceptibility Genes with Weak or No Marginal Effect

article

Study of two ectopeptidases in the susceptibility to celiac disease: two newly identified polymorphisms of dipeptidylpeptidase IV.

artículo científico publicado en 2000

Susceptibility to coeliac disease in Tunisian children and GM immunoglobulin allotypes.

artículo científico publicado en 1999

Synergistic effect of two HLA heterodimers in the susceptibility to celiac disease in Tunisia ⬇️

artículo científico publicado el 1 de enero de 1997

Systematic search of susceptibility loci with methods using gametic disequilibrium

scientific article published on 01 January 1995

Testing parental imprinting in insulin-dependent diabetes mellitus by the marker-association-segregation-chi 2 method.

artículo científico publicado en 1995

The HLA component of type I diabetes.

artículo científico publicado en 2000

The Missing Heritability Paradigm: A Dramatic Resurgence of the GIGO Syndrome in Genetics

article

The ordered transmission disequilibrium test: detection of modifier genes

article

The triangle test statistic (TTS): a test of genetic homogeneity using departure from the triangle constraints in IBD distribution among affected sib-pairs

artículo científico publicado en 2000

Two-disease locus model: Sib pair method using information on both HLA and Gm

artículo científico publicado en 1986

Use of closely related affected individuals for the genetic study of complex diseases in founder populations.

artículo científico publicado en 2000

Use of haplotype information to test involvement of the LRP gene in Alzheimer's disease in the French population

article

Using affected sib-pairs to uncover rare disease variants

artículo científico publicado en 2012

Using genomic inbreeding coefficient estimates for homozygosity mapping of rare recessive traits: application to Taybi-Linder syndrome.

artículo científico publicado en 2006

Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4

article

Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis

artículo científico publicado en 2006

Variable Age at Onset in Insulin-Dependent Diabetes Mellitus, by the Marker-Association-Segregation-χ2 Method ⬇️

artículo científico publicado el 1 de julio de 1997

Will formal genetics become dispensable?

artículo científico publicado en 2013

[Genetic predisposition for multiple sclerosis]

artículo científico publicado en 2000

[Genetics of Alzheimer's disease]

scientific article published on 01 January 1998

[Interaction between HLA and Gm for susceptibility to insulin-dependent diabetes]

scientific article published on 01 January 1985

Lista de obras de Françoise Clerget-Darpoux

A gene for Meckel syndrome maps to chromosome 11q13.

A new methodology for analysis of HLA-associated diseases?

A systematic study of oligodendrocyte growth factors as candidates for genetic susceptibility to MS

APOE promoter polymorphisms do not confer independent risk for Alzheimer's disease in a French population.

About the use of APOE in Alzheimer's disease studies.

Absence of the amyloid precursor protein gene mutation (APP717: Val->Ile) in 85 cases of early onset Alzheimer's disease.

Allele variations in the OCA2 gene (pink-eyed-dilution locus) are associated with genetic susceptibility to melanoma

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

An exclusion map covering the whole genome: a new challenge for genetic epidemiologists?

An ordered subset approach to including covariates in the transmission disequilibrium test

Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex

Apolipoprotein E epsilon4 allele and familial aggregation of Alzheimer disease.

Apolipoprotein E gene in frontotemporal dementia: an association study and meta-analysis

Application of the lod score method to detection of linkage between HLA and juvenile insulin-dependent diabetes.

Are Linkage Analysis and the Collection of Family Data Dead? Prospects for Family Studies in the Age of Genome-Wide Association

Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?

Assessing the effect of multiple linkage tests in complex diseases.

Association between a genetic trait and a marker: Discrimination between epistasis and gametic disequilibrium

Association between the extended tau haplotype and frontotemporal dementia

Association in Multifactorial Traits: How to Deal with Rare Observations?

Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA

Bias of the estimated recombination fraction and lod score due to an association between a disease gene and a marker gene.

Candidate gene region 2q33 in European families with coeliac disease

Caution in the interpretation of MLS

Chromosome 17q22–q24 and multiple sclerosis genetic susceptibility

Chromosome 21 scan in Down syndrome reveals DSCAM as a predisposing locus in Hirschsprung disease

Comparing the power of linkage detection by the transmission disequilibrium test and the identity-by-descent test

Comparison of family based haplotype methods using intragenic SNPs in candidate genes

Conclusions of segregation analysis for family data generated under two-locus models.

Consanguinity and the sib-pair method: an approach using identity by descent between and within individuals.

Cytokines in genetic susceptibility to multiple sclerosis: a candidate gene approach. French Multiple Sclerosis Genetics Group.

De novo presenilin 1 mutations are rare in clinically sporadic, early onset Alzheimer's disease cases. French Alzheimer's Disease Study Group.

Detection and modeling of disease susceptibility locus effects: How much can be learned from contrast of populations?

Detection of susceptibility loci by genome-wide linkage analysis

Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis

Discrimination between genetic models for insulin dependent diabetes mellitus

Discussing gene-gene interaction: warning--translating equations to English may result in jabberwocky

Développement embryonnaire précoce

Estimation of the inbreeding coefficient through use of genomic data

Evidence for Linkage Disequilibrium Between HLA-DRB1 Gene and Multiple Sclerosis

Evidence for apolipoprotein E epsilon 4 association in early-onset Alzheimer's patients with late-onset relatives.

Excess of maternal HLA-DR3 antigens in HLA DR3,4 positive Type 1 (insulin-dependent) diabetic patients

Existence of a genetic risk factor on chromosome 5q in Italian Coeliac Disease families

Functional variants of POC5 identified in patients with idiopathic scoliosis

Genealogical and genetic structure.

Genetic analysis of multiple sclerosis in Europeans: French data

Genetic interaction of CTLA-4 with HLA-DR15 in multiple sclerosis patients

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Genetic study of transthyretin amyloid neuropathies: carrier risks among French and Portuguese families.

Genetics of Alzheimer's disease

Genome search in celiac disease.

Génétique épidémiologique de la maladie cœliaque

HLA related genetic risk for coeliac disease.

HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease.

HLA-DRB1*15 allele influences the later course of relapsing remitting multiple sclerosis

HLA-associated diseases: a new method for performing linkage analysis with other markers than HLA.

Hereditary retinoblastoma: can balanced insertion entirely explain the differences of expressivity among families?

Heterogeneity of marker allele frequencies hinders interpretation of linkage analysis: Illustration on chromosome 18 markers ⬇️

High risk genotypes for celiac disease

Homogeneity of asthma genome scan results.

IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients

IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations.

Identifying modifier genes of monogenic disease: strategies and difficulties.

Impact of parental relationships in maximum lod score affected sib-pair method

Improved use of SNP information to detect the role of genes.

Indication of linkage and genetic heterogeneity for asthma and atopy on chromosomes 8p and 12q in 107 French EGEA families.

Indication of linkage and genetic heterogeneity of asthma according to age at onset on chromosome 7q in 107 French EGEA families.

Influence of HLA-DRB1 P4 binding pocket electric charge on rheumatoid arthritis (RA) susceptibility.

Interactive effect of HLA and Gm and genetic heterogeneity tested in 79 rheumatoid arthritis families.

Interactive effect of two candidate genes in a disease: extension of the marker-association-segregation chi(2) method.

Intercellular adhesion molecule-1: a protective haplotype against multiple sclerosis.

Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study

Investigation of the HLA component involved in rheumatoid arthritis (RA) by using the marker association-segregation chi-square (MASC) method: rejection of the unifying-shared-epitope hypothesis ⬇️

Is a single mutation at the same locus responsible for all affected cases in a large Alzheimer pedigree (FAD4)?

Is the saitohin gene involved in neurodegenerative diseases?

Juvenile insulin-dependent diabetes: a possible susceptibility gene in interaction with HLA

Lack of Correlation Between Genotype and Phenotype in Celiac Disease ⬇️

Letter to the Editor: No evidence for association between the EIF2B5 gene and multiple sclerosis in French families

Linkage and association study of the CTLA-4 region in coeliac disease for Italian and Tunisian populations.