Lista de obras - Gosia Trynka - Dominio Público Uruguay

A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells

scientific article published on 13 May 2020

A genetic perspective on coeliac disease

artículo científico publicado en 2010

A genetic variant in the region of MMP-9 is associated with serum levels and progression of joint damage in rheumatoid arthritis

artículo científico publicado en 2013

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease

scientific journal article

Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease

artículo científico publicado en 2009

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

artículo científico publicado en 2016

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

artículo científico publicado en 2012

Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases

scientific article published on 23 September 2019

Chromatin marks identify critical cell types for fine mapping complex trait variants

artículo científico publicado en 2012

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling

artículo científico publicado en 2009

Common and different genetic background for rheumatoid arthritis and coeliac disease

artículo científico publicado en 2009

Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.

artículo científico publicado en 2015

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

artículo científico publicado en 2012

Complex nature of SNP genotype effects on gene expression in primary human leucocytes

artículo científico publicado en 2009

Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity

artículo científico publicado en 2015

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

artículo científico publicado en 2011

Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays

artículo científico publicado en 2008

Disentangling effects of colocalizing genomic annotations to functionally prioritize non-coding variants within complex trait loci

Enhancers looping to target genes

artículo científico publicado en 2017

Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection

artículo científico publicado en 2010

Exome sequencing in a family segregating for celiac disease

artículo científico publicado en 2011

Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

artículo científico publicado en 2015

Functional studies of GWAS variants are gaining momentum

artículo científico publicado en 2020

Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.

artículo científico publicado en 2008

Genetics of rheumatoid arthritis contributes to biology and drug discovery

artículo científico publicado en 2013

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

artículo científico publicado en 2013

Genomic profiling of T cell activation reveals dependency of memory T cells on CD28 costimulation

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation

artículo científico publicado en 2020

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

artículo científico publicado en 2012

ImmunoChip study implicates antigen presentation to T cells in narcolepsy

artículo científico publicado en 2013

Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease

artículo científico publicado en 2019

Immunogenomic approaches to understand the function of immune disease variants

artículo científico publicado en 2017

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

scientific journal article

Multiple common variants for celiac disease influencing immune gene expression

artículo científico publicado en 2010

Newly identified genetic risk variants for celiac disease related to the immune response

artículo científico publicado en 2008

Potential celiac patients: a model of celiac disease pathogenesis.

artículo científico publicado en 2011

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

artículo científico publicado en 2011

Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells

artículo científico publicado en 2014

Robust temporal map of human in vitro myelopoiesis using single-cell genomics

scientific article published on 24 May 2022

Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

scientific article published on 14 April 2020

Six new coeliac disease loci replicated in an Italian population confirm association with coeliac disease.

artículo científico publicado en 2008

The single-cell eQTLGen consortium

artículo científico publicado en 2020

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

artículo científico publicado en 2011

Variants in neuropeptide Y receptor 1 and 5 are associated with nutrient-specific food intake and are under recent selection in Europeans.

artículo científico publicado en 2009

Lista de obras de Gosia Trynka

A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells

A genetic perspective on coeliac disease

A genetic variant in the region of MMP-9 is associated with serum levels and progression of joint damage in rheumatoid arthritis

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease

Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases

Chromatin marks identify critical cell types for fine mapping complex trait variants

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling

Common and different genetic background for rheumatoid arthritis and coeliac disease

Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Complex nature of SNP genotype effects on gene expression in primary human leucocytes

Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays

Disentangling effects of colocalizing genomic annotations to functionally prioritize non-coding variants within complex trait loci

Enhancers looping to target genes

Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection

Exome sequencing in a family segregating for celiac disease

Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

Functional studies of GWAS variants are gaining momentum

Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

Genomic profiling of T cell activation reveals dependency of memory T cells on CD28 costimulation

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

ImmunoChip study implicates antigen presentation to T cells in narcolepsy

Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease

Immunogenomic approaches to understand the function of immune disease variants

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

Multiple common variants for celiac disease influencing immune gene expression

Newly identified genetic risk variants for celiac disease related to the immune response

Potential celiac patients: a model of celiac disease pathogenesis.

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells

Robust temporal map of human in vitro myelopoiesis using single-cell genomics

Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

Six new coeliac disease loci replicated in an Italian population confirm association with coeliac disease.

The single-cell eQTLGen consortium

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

Variants in neuropeptide Y receptor 1 and 5 are associated with nutrient-specific food intake and are under recent selection in Europeans.