Lista de obras - Thomas Arnesen - Dominio Público Uruguay

(Hyper)tension release by N-terminal acetylation

artículo científico publicado en 2015

<i>NAA10</i> p.(D10G) and <i>NAA10</i> p.(L11R) Variants Hamper Formation of the NatA N-Terminal Acetyltransferase Complex

scientific article published on 26 November 2020

A Role for Human N-alpha Acetyltransferase 30 (Naa30) in Maintaining Mitochondrial Integrity

artículo científico publicado en 2016

A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant

artículo científico publicado en 2014

A novel NAA10 p.(R83H) variant with impaired acetyltransferase activity identified in two boys with ID and microcephaly

artículo científico publicado en 2019

A novel NAA10 variant with impaired acetyltransferase activity causes developmental delay, intellectual disability, and hypertrophic cardiomyopathy

artículo científico publicado en 2018

A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1)

artículo científico publicado en 2009

A novel type of deletion in the CDKN2A gene identified in a melanoma-prone family

artículo científico publicado en 2006

A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates

artículo científico publicado en 2009

Actin polymerization and cell motility are affected by NAA80-mediated posttranslational N-terminal acetylation of actin

artículo científico publicado en 2018

Actin's N-terminal acetyltransferase uncovered

artículo científico publicado en 2018

An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity

scientific journal article

Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects

artículo científico publicado en 2014

Bioinformatics analysis of a Saccharomyces cerevisiae N-terminal proteome provides evidence of alternative translation initiation and post-translational N-terminal acetylation

artículo científico publicado en 2011

Characterization of Evolutionarily Conserved NatC and NatA-N-Terminal Acetyltransferase Complexes

artículo científico publicado en 2019

Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase

artículo científico publicado en 2006

Classification and phylogeny for the annotation of novel eukaryotic GNAT acetyltransferases

artículo científico publicado en 2020

Clinical Characteristics and Long-Term Outcome of Primary Aldosteronism in a Norwegian Population

artículo científico publicado en 2017

Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex

artículo científico publicado en 2006

Co-translational, Post-translational, and Non-catalytic Roles of N-Terminal Acetyltransferases

scientific article published on 13 March 2019

Complementary somatic mutations of KCNJ5, ATP1A1, and ATP2B3 in sporadic aldosterone producing adrenal adenomas.

artículo científico publicado en 2014

Composition and biological significance of the human Nα-terminal acetyltransferases

artículo científico publicado en 2009

Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation

scientific journal article

DTNB-Based Quantification of In Vitro Enzymatic N-Terminal Acetyltransferase Activity

artículo científico publicado en 2017

De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females

artículo científico publicado en 2015

Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1 localization

artículo científico publicado en 2017

Depletion of the human Nα-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition

artículo científico publicado en 2010

Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors

artículo científico publicado en 2013

Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis

artículo científico publicado en 2015

Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice

artículo científico publicado en 2024

Expanding the Phenotype Associated with NAA10-Related N-Terminal Acetylation Deficiency

artículo científico publicado en 2016

Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms

artículo científico publicado en 2005

First Things First: Vital Protein Marks by N-Terminal Acetyltransferases

artículo científico publicado en 2016

HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain

artículo científico publicado en 2005

HPLC-based quantification of in vitro N-terminal acetylation

artículo científico publicado en 2013

Holding it together: Naa60 at the Golgi

artículo científico publicado en 2015

Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity

artículo científico publicado en 2009

Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study

artículo científico publicado en 2012

Identification and characterization of the human ARD1-NATH protein acetyltransferase complex

artículo científico publicado en 2005

Identification of an alternatively spliced nuclear isoform of human N-terminal acetyltransferase Naa30.

artículo científico publicado en 2017

Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression

artículo científico publicado en 2008

In-gel N-acetylation for the quantification of the degree of protein in vivo N-terminal acetylation

artículo científico publicado en 2013

Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex

artículo científico publicado en 2006

Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha

artículo científico publicado en 2005

Investigating the functionality of a ribosome-binding mutant of NAA15 using Saccharomyces cerevisiae.

artículo científico publicado en 2018

Involvement of N-acetyltransferase human in the cytotoxic activity of 5-fluorouracil

artículo científico publicado en 2009

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization

artículo científico publicado en 2009

Massively parallel sequencing identifies a previously unrecognized X-linked disorder resulting in lethality in male infants owing to amino-terminal acetyltransferase deficiency.

artículo científico publicado en 2011

Mechanism of actin N-terminal acetylation

artículo científico publicado en 2020

Microscopy-based Saccharomyces cerevisiae complementation model reveals functional conservation and redundancy of N-terminal acetyltransferases

artículo científico publicado en 2016

Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

artículo científico publicado en 2013

Molecular determinants of the N-terminal acetyltransferase Naa60 anchoring to the Golgi membrane.

artículo científico publicado en 2017

Molecular, cellular, and physiological significance of N-terminal acetylation.

artículo científico

N-terminal Acetylation Levels Are Maintained During Acetyl-CoA Deficiency in

scientific article published on 27 August 2018

N-terminal acetylation by NatC is not a general determinant for substrate subcellular localization in Saccharomyces cerevisiae

artículo científico publicado en 2013

N-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus

artículo científico publicado en 2020

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

artículo científico publicado en 2012

N-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases

artículo científico publicado en 2015

N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects

artículo científico publicado en 2015

NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant - a case report.

artículo científico publicado en 2018

NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment

artículo científico publicado en 2015

NAA80 is actin's N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility

artículo científico publicado en 2018

Naa10 in development and disease.

artículo científico publicado en 2015

Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion

artículo científico publicado en 2016

NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation

artículo científico publicado en 2011

Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway

artículo científico publicado en 2013

PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin

artículo científico publicado en 2020

Protein N-terminal acetylation: NAT 2007-2008 Symposia

artículo científico publicado en 2009

Protein N-terminal acetyltransferases act as N-terminal propionyltransferases in vitro and in vivo

artículo científico publicado en 2013

Protein N-terminal acetyltransferases in cancer

artículo científico publicado en 2012

Protein N-terminal acetyltransferases: when the start matters

artículo científico publicado en 2012

Protein alpha-N-acetylation studied by N-terminomics

artículo científico publicado en 2011

Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase

artículo científico publicado en 2011

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

artículo científico publicado en 2009

Specificity and versatility of substrate binding sites in four catalytic domains of human N-terminal acetyltransferases

artículo científico publicado en 2012

Spotlight on protein N-terminal acetylation

scientific article published on 27 July 2018

Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.

artículo científico publicado en 2018

Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation

artículo científico publicado en 2011

The N-terminal acetyltransferase Naa10 is essential for zebrafish development

artículo científico publicado en 2015

The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation

artículo científico publicado en 2010

The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4

artículo científico publicado en 2011

The protein Nalpha-terminal acetyltransferase hNaa10p (hArd1) is phosphorylated in HEK293 cells

artículo científico publicado en 2009

The protein acetyltransferase ARD1: a novel cancer drug target?

artículo científico publicado en 2008

The world of protein acetylation

artículo científico publicado en 2016

Towards a Functional Understanding of Protein N-Terminal Acetylation ⬇️

artículo científico publicado el 31 de mayo de 2011

Truncating Variants in NAA15 Are Associated with Variable Levels of Intellectual Disability, Autism Spectrum Disorder, and Congenital Anomalies.

artículo científico publicado en 2018

Using VAAST to Identify an X-linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency.

artículo científico publicado en 2011

Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency

artículo científico publicado en 2011

[14C]-Acetyl-Coenzyme A-Based In Vitro N-Terminal Acetylation Assay.

artículo científico publicado en 2017

Lista de obras de Thomas Arnesen

(Hyper)tension release by N-terminal acetylation

<i>NAA10</i> p.(D10G) and <i>NAA10</i> p.(L11R) Variants Hamper Formation of the NatA N-Terminal Acetyltransferase Complex

A Role for Human N-alpha Acetyltransferase 30 (Naa30) in Maintaining Mitochondrial Integrity

A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant

A novel NAA10 p.(R83H) variant with impaired acetyltransferase activity identified in two boys with ID and microcephaly

A novel NAA10 variant with impaired acetyltransferase activity causes developmental delay, intellectual disability, and hypertrophic cardiomyopathy

A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1)

A novel type of deletion in the CDKN2A gene identified in a melanoma-prone family

A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates

Actin polymerization and cell motility are affected by NAA80-mediated posttranslational N-terminal acetylation of actin

Actin's N-terminal acetyltransferase uncovered

An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity

Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects

Bioinformatics analysis of a Saccharomyces cerevisiae N-terminal proteome provides evidence of alternative translation initiation and post-translational N-terminal acetylation

Characterization of Evolutionarily Conserved NatC and NatA-N-Terminal Acetyltransferase Complexes

Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase

Classification and phylogeny for the annotation of novel eukaryotic GNAT acetyltransferases

Clinical Characteristics and Long-Term Outcome of Primary Aldosteronism in a Norwegian Population

Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex

Co-translational, Post-translational, and Non-catalytic Roles of N-Terminal Acetyltransferases

Complementary somatic mutations of KCNJ5, ATP1A1, and ATP2B3 in sporadic aldosterone producing adrenal adenomas.

Composition and biological significance of the human Nα-terminal acetyltransferases

Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation

DTNB-Based Quantification of In Vitro Enzymatic N-Terminal Acetyltransferase Activity

De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females

Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1 localization

Depletion of the human Nα-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition

Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors

Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis

Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice

Expanding the Phenotype Associated with NAA10-Related N-Terminal Acetylation Deficiency

Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms

First Things First: Vital Protein Marks by N-Terminal Acetyltransferases

HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain

HPLC-based quantification of in vitro N-terminal acetylation

Holding it together: Naa60 at the Golgi

Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity

Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study

Identification and characterization of the human ARD1-NATH protein acetyltransferase complex

Identification of an alternatively spliced nuclear isoform of human N-terminal acetyltransferase Naa30.

Identification of the human N(alpha)-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression

In-gel N-acetylation for the quantification of the degree of protein in vivo N-terminal acetylation

Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex

Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha

Investigating the functionality of a ribosome-binding mutant of NAA15 using Saccharomyces cerevisiae.

Involvement of N-acetyltransferase human in the cytotoxic activity of 5-fluorouracil

Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization

Massively parallel sequencing identifies a previously unrecognized X-linked disorder resulting in lethality in male infants owing to amino-terminal acetyltransferase deficiency.

Mechanism of actin N-terminal acetylation

Microscopy-based Saccharomyces cerevisiae complementation model reveals functional conservation and redundancy of N-terminal acetyltransferases

Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

Molecular determinants of the N-terminal acetyltransferase Naa60 anchoring to the Golgi membrane.

Molecular, cellular, and physiological significance of N-terminal acetylation.

N-terminal Acetylation Levels Are Maintained During Acetyl-CoA Deficiency in

N-terminal acetylation by NatC is not a general determinant for substrate subcellular localization in Saccharomyces cerevisiae

N-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

N-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases

N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects

NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant - a case report.

NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment

NAA80 is actin's N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility

Naa10 in development and disease.

Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion

NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation

Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway

PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin

Protein N-terminal acetylation: NAT 2007-2008 Symposia

Protein N-terminal acetyltransferases act as N-terminal propionyltransferases in vitro and in vivo

Protein N-terminal acetyltransferases in cancer

Protein N-terminal acetyltransferases: when the start matters

Protein alpha-N-acetylation studied by N-terminomics

Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

Specificity and versatility of substrate binding sites in four catalytic domains of human N-terminal acetyltransferases

Spotlight on protein N-terminal acetylation

Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.

Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation

The N-terminal acetyltransferase Naa10 is essential for zebrafish development