Lista de obras - Darrick Carter - Dominio Público Uruguay

A Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines

artículo científico publicado en 2017

A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7

artículo científico publicado en 2014

A structure-function approach to optimizing TLR4 ligands for human vaccines

artículo científico publicado en 2016

A synthetic TLR4 agonist formulated in an emulsion enhances humoral and Type 1 cellular immune responses against GMZ2--a GLURP-MSP3 fusion protein malaria vaccine candidate

artículo científico publicado en 2011

Accounting for adjuvant-induced artifacts in the characterization of vaccine formulations by polyacrylamide gel electrophoresis

artículo científico publicado en 2017

Adjuvants for malaria vaccines

artículo científico publicado en 2009

Alga-produced malaria transmission-blocking vaccine candidate Pfs25 formulated with a human use-compatible potent adjuvant induces high-affinity antibodies that block Plasmodium falciparum infection of mosquitoes

artículo científico publicado en 2015

An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

artículo científico publicado en 2020

Biased cellular locations of tandem repeat antigens in African trypanosomes

artículo científico publicado en 2011

Chemical deglycosylation can induce methylation, succinimide formation, and isomerization

artículo científico publicado en 2001

Chitin microneedles for an easy-to-use tuberculosis skin test

artículo científico publicado en 2013

Clinical adjuvant combinations stimulate potent B-cell responses in vitro by activating dermal dendritic cells

artículo científico publicado en 2013

Coadministration of epithelial junction opener JO-1 improves the efficacy and safety of chemotherapeutic drugs

artículo científico publicado en 2012

Combinations of TLR4 and TLR7/8 Adjuvants Administered via the ID or IN Routes Generate Different Vaccine Antigen-specific Immune Outcomes in Minipigs

Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study

artículo científico publicado en 2016

Comparison of multiple adjuvants on the stability and immunogenicity of a clade C HIV-1 gp140 trimer

artículo científico publicado en 2014

Correlates of GLA family adjuvants' activities

artículo científico publicado en 2018

Crithidia fasciculata: isolation, sequencing, and expression of the hypoxanthine-guanine phosphoribosyltransferase gene

artículo científico publicado en 1996

Cross-species protection: Schistosoma mansoni Sm-p80 vaccine confers protection against Schistosoma haematobium in hamsters and baboons

scientific article published on 04 January 2014

Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop

artículo científico publicado en 1996

Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.

artículo científico publicado en 1998

Detection of mammaglobin in the sera of patients with breast cancer.

artículo científico publicado en 2002

Determination of Β-isomerized aspartic acid as the corresponding alcohol

artículo científico publicado en 1994

Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant

artículo científico publicado en 2011

Development of a high density hemagglutinin protein microarray to determine the breadth of influenza antibody responses

artículo científico publicado en 2013

Development of a schistosomiasis vaccine

artículo científico publicado en 2015

Differential localization of alternatively spliced hypoxanthine-xanthine-guanine phosphoribosyltransferase isoforms in Toxoplasma gondii

artículo científico publicado en 2005

E-104 Design and Development of Adjuvants for HIV Vaccines

article

E114 Rational Design and Clinical Development of New Adjuvants

article

Effective Combination Adjuvants Engage Both TLR and Inflammasome Pathways To Promote Potent Adaptive Immune Responses

article

Emulsion-based vaccine adjuvants

Epithelial Junction Opener Improves Oncolytic Adenovirus Therapy in Mouse Tumor Models

artículo científico publicado en 2016

Exploring the protein landscape in ramachandran space: it's not just psi-phi

artículo científico publicado en 2009

Expression and purification of immunologically reactive DPPD, a recombinant Mycobacterium tuberculosis skin test antigen, using Mycobacterium smegmatis and Escherichia coli host cells

artículo científico publicado en 2004

Expression, purification, and characterization of uracil phosphoribosyltransferase from Toxoplasma gondii.

artículo científico publicado en 1997

Flexgrepps--flexible greedy peptide pool search: computation of near-optimal sets of degenerate polypeptides for antigenic screening

artículo científico publicado en 2012

Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 agonist, promotes potent systemic and mucosal responses to intranasal immunization with HIVgp140.

artículo científico publicado en 2012

Glucopyranosyl lipid A adjuvant significantly enhances HIV specific T and B cell responses elicited by a DNA-MVA-protein vaccine regimen

artículo científico publicado en 2014

IL-18 and Subcapsular Lymph Node Macrophages are Essential for Enhanced B Cell Responses with TLR4 Agonist Adjuvants.

artículo científico publicado en 2016

Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis

artículo científico publicado en 2002

Immunological dominance of Trypanosoma cruzi tandem repeat proteins

artículo científico publicado en 2008

Innovations in emulsion technology

article

Insight toward early diagnosis of leprosy through analysis of the developing antibody responses of Mycobacterium leprae-infected armadillos.

artículo científico publicado en 2010

Intracellular Signaling and Desmoglein 2 Shedding Triggered by Human Adenoviruses Ad3, Ad14, and Ad14P1.

artículo científico publicado en 2015

Localization and Targeting of the Leishmania donovani Hypoxanthine-Guanine Phosphoribosyltransferase to the Glycosome

artículo científico publicado en 1998

Longevity of Sm-p80-specific antibody responses following vaccination with Sm-p80 vaccine in mice and baboons and transplacental transfer of Sm-p80-specific antibodies in a baboon

artículo científico publicado en 2014

Mammaglobin: a candidate diagnostic marker for breast cancer

artículo científico publicado en 2004

Molecular and biochemical studies on the hypoxanthine-guanine phosphoribosyltransferases of the pathogenic haemoflagellates

artículo científico publicado en 1997

Multi-epitope proteins for improved serological detection of Trypanosoma cruzi infection and Chagas Disease.

artículo científico publicado en 2015

Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance

artículo científico publicado en 1997

Optimized subunit vaccine protects against experimental leishmaniasis

scientific article published on 26 September 2009

Physicochemical structure of a polyacrylic acid stabilized nanoparticle alum (nanoalum) adjuvant governs TH1 differentiation of CD4+ T cells

scientific article published on 13 January 2020

Preclinical safety and efficacy studies with an affinity-enhanced epithelial junction opener and PEGylated liposomal doxorubicin

artículo científico publicado en 2015

Preclinical safety, pharmacokinetics, pharmacodynamics, and biodistribution studies with Ad35K++ protein: a novel rituximab cotherapeutic

artículo científico publicado en 2016

Protein engineering to target complement evasion in cancer

artículo científico publicado en 2013

Protein nanovaccine confers robust immunity against Toxoplasma

artículo científico publicado en 2017

Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer

artículo científico publicado en 2002

Rational design and evaluation of a multiepitope chimeric fusion protein with the potential for leprosy diagnosis

artículo científico publicado en 2009

Recombinant Ad35 adenoviral proteins as potent modulators of human T cell activation

artículo científico publicado en 2014

Recombinant expression, purification, and characterization of Toxoplasma gondii adenosine kinase

article

Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice

artículo científico publicado en 2016

Role of adjuvants in modeling the immune response

artículo científico publicado en 2010

Selection of antigens and development of prototype tests for point-of-care leprosy diagnosis.

artículo científico publicado en 2008

Sensitivity of undifferentiated, high-TCR density CD8+ cells to methylene groups appended to tumor antigen determines their differentiation or death

artículo científico publicado en 2005

Sequence-Based Computational Approaches to Vaccine Discovery and Design

article published in 2012

Serological characterizations of tandem repeat proteins for detection of African trypanosome infection in cattle.

artículo científico publicado en 2011

Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons

artículo científico publicado en 2017

Specific IgG antibody responses may be used to monitor leprosy treatment efficacy and as recurrence prognostic markers

article

Squalene emulsion potentiates the adjuvant activity of the TLR4 agonist, GLA, via inflammatory caspases, IL-18, and IFN-γ.

artículo científico publicado en 2014

Structure-based Design of JOC-x, a Conjugatable Tumor Tight Junction Opener to Enhance Cancer Therapy

artículo científico publicado en 2019

Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen

artículo científico publicado en 2016

TLR4 and TLR7/8 Adjuvant Combinations Generate Different Vaccine Antigen-Specific Immune Outcomes in Minipigs when Administered via the ID or IN Routes

artículo científico publicado en 2016

Targeting TLRs expands the antibody repertoire in response to a malaria vaccine

artículo científico publicado en 2011

The adjuvant GLA-AF enhances human intradermal vaccine responses

article

The science of vaccine adjuvants: advances in TLR4 ligand adjuvants

artículo científico publicado en 2016

Transient removal of CD46 is safe and increases B-cell depletion by rituximab in CD46 transgenic mice and macaques

artículo científico publicado en 2012

Trapping succinimides in aged polypeptides by chemical reduction

artículo científico publicado en 1994

Upregulated expression of B-cell antigen family tandem repeat proteins by Leishmania amastigotes

artículo científico publicado en 2010

Use of ProteinChip array surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to identify thymosin beta-4, a differentially secreted protein from lymphoblastoid cell lines

artículo científico publicado en 2003

Use of an Sm-p80-based therapeutic vaccine to kill established adult schistosome parasites in chronically infected baboons

artículo científico publicado en 2014

Vaccine adjuvant activity of emulsified oils from species of the Pinaceae family

artículo científico publicado en 2019

Lista de obras de Darrick Carter

A Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines

A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7

A structure-function approach to optimizing TLR4 ligands for human vaccines

A synthetic TLR4 agonist formulated in an emulsion enhances humoral and Type 1 cellular immune responses against GMZ2--a GLURP-MSP3 fusion protein malaria vaccine candidate

Accounting for adjuvant-induced artifacts in the characterization of vaccine formulations by polyacrylamide gel electrophoresis

Adjuvants for malaria vaccines

Alga-produced malaria transmission-blocking vaccine candidate Pfs25 formulated with a human use-compatible potent adjuvant induces high-affinity antibodies that block Plasmodium falciparum infection of mosquitoes

An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

Biased cellular locations of tandem repeat antigens in African trypanosomes

Chemical deglycosylation can induce methylation, succinimide formation, and isomerization

Chitin microneedles for an easy-to-use tuberculosis skin test

Clinical adjuvant combinations stimulate potent B-cell responses in vitro by activating dermal dendritic cells

Coadministration of epithelial junction opener JO-1 improves the efficacy and safety of chemotherapeutic drugs

Combinations of TLR4 and TLR7/8 Adjuvants Administered via the ID or IN Routes Generate Different Vaccine Antigen-specific Immune Outcomes in Minipigs

Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study

Comparison of multiple adjuvants on the stability and immunogenicity of a clade C HIV-1 gp140 trimer

Correlates of GLA family adjuvants' activities

Crithidia fasciculata: isolation, sequencing, and expression of the hypoxanthine-guanine phosphoribosyltransferase gene

Cross-species protection: Schistosoma mansoni Sm-p80 vaccine confers protection against Schistosoma haematobium in hamsters and baboons

Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop

Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.

Detection of mammaglobin in the sera of patients with breast cancer.

Determination of Β-isomerized aspartic acid as the corresponding alcohol

Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant

Development of a high density hemagglutinin protein microarray to determine the breadth of influenza antibody responses

Development of a schistosomiasis vaccine

Differential localization of alternatively spliced hypoxanthine-xanthine-guanine phosphoribosyltransferase isoforms in Toxoplasma gondii

E-104 Design and Development of Adjuvants for HIV Vaccines

E114 Rational Design and Clinical Development of New Adjuvants

Effective Combination Adjuvants Engage Both TLR and Inflammasome Pathways To Promote Potent Adaptive Immune Responses

Emulsion-based vaccine adjuvants

Epithelial Junction Opener Improves Oncolytic Adenovirus Therapy in Mouse Tumor Models

Exploring the protein landscape in ramachandran space: it's not just psi-phi

Expression and purification of immunologically reactive DPPD, a recombinant Mycobacterium tuberculosis skin test antigen, using Mycobacterium smegmatis and Escherichia coli host cells

Expression, purification, and characterization of uracil phosphoribosyltransferase from Toxoplasma gondii.

Flexgrepps--flexible greedy peptide pool search: computation of near-optimal sets of degenerate polypeptides for antigenic screening

Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 agonist, promotes potent systemic and mucosal responses to intranasal immunization with HIVgp140.

Glucopyranosyl lipid A adjuvant significantly enhances HIV specific T and B cell responses elicited by a DNA-MVA-protein vaccine regimen

IL-18 and Subcapsular Lymph Node Macrophages are Essential for Enhanced B Cell Responses with TLR4 Agonist Adjuvants.

Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis

Immunological dominance of Trypanosoma cruzi tandem repeat proteins

Innovations in emulsion technology

Insight toward early diagnosis of leprosy through analysis of the developing antibody responses of Mycobacterium leprae-infected armadillos.

Intracellular Signaling and Desmoglein 2 Shedding Triggered by Human Adenoviruses Ad3, Ad14, and Ad14P1.

Localization and Targeting of the Leishmania donovani Hypoxanthine-Guanine Phosphoribosyltransferase to the Glycosome

Longevity of Sm-p80-specific antibody responses following vaccination with Sm-p80 vaccine in mice and baboons and transplacental transfer of Sm-p80-specific antibodies in a baboon

Mammaglobin: a candidate diagnostic marker for breast cancer

Molecular and biochemical studies on the hypoxanthine-guanine phosphoribosyltransferases of the pathogenic haemoflagellates

Multi-epitope proteins for improved serological detection of Trypanosoma cruzi infection and Chagas Disease.

Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance

Optimized subunit vaccine protects against experimental leishmaniasis

Physicochemical structure of a polyacrylic acid stabilized nanoparticle alum (nanoalum) adjuvant governs TH1 differentiation of CD4+ T cells

Preclinical safety and efficacy studies with an affinity-enhanced epithelial junction opener and PEGylated liposomal doxorubicin

Preclinical safety, pharmacokinetics, pharmacodynamics, and biodistribution studies with Ad35K++ protein: a novel rituximab cotherapeutic

Protein engineering to target complement evasion in cancer

Protein nanovaccine confers robust immunity against Toxoplasma

Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer

Rational design and evaluation of a multiepitope chimeric fusion protein with the potential for leprosy diagnosis

Recombinant Ad35 adenoviral proteins as potent modulators of human T cell activation

Recombinant expression, purification, and characterization of Toxoplasma gondii adenosine kinase

Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice

Role of adjuvants in modeling the immune response

Selection of antigens and development of prototype tests for point-of-care leprosy diagnosis.

Sensitivity of undifferentiated, high-TCR density CD8+ cells to methylene groups appended to tumor antigen determines their differentiation or death

Sequence-Based Computational Approaches to Vaccine Discovery and Design

Serological characterizations of tandem repeat proteins for detection of African trypanosome infection in cattle.

Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons

Specific IgG antibody responses may be used to monitor leprosy treatment efficacy and as recurrence prognostic markers

Squalene emulsion potentiates the adjuvant activity of the TLR4 agonist, GLA, via inflammatory caspases, IL-18, and IFN-γ.

Structure-based Design of JOC-x, a Conjugatable Tumor Tight Junction Opener to Enhance Cancer Therapy

Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen

TLR4 and TLR7/8 Adjuvant Combinations Generate Different Vaccine Antigen-Specific Immune Outcomes in Minipigs when Administered via the ID or IN Routes

Targeting TLRs expands the antibody repertoire in response to a malaria vaccine

The adjuvant GLA-AF enhances human intradermal vaccine responses

The science of vaccine adjuvants: advances in TLR4 ligand adjuvants

Transient removal of CD46 is safe and increases B-cell depletion by rituximab in CD46 transgenic mice and macaques

Trapping succinimides in aged polypeptides by chemical reduction

Upregulated expression of B-cell antigen family tandem repeat proteins by Leishmania amastigotes

Use of ProteinChip array surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to identify thymosin beta-4, a differentially secreted protein from lymphoblastoid cell lines