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Lista de obras de Timothy Stinear

1,2,4-Oxadiazole antimicrobials act synergistically with daptomycin and display rapid kill kinetics against MDR Enterococcus faecium.

artículo científico publicado en 2018

A Genomic Approach to Resolving Relapse versus Reinfection among Four Cases of Buruli Ulcer.

artículo científico publicado en 2015

A diagnostic PCR assay for the detection of an Australian epidemic strain of Pseudomonas aeruginosa

artículo científico publicado en 2010

A glimpse into the past and predictions for the future: the molecular evolution of the tuberculosis agent

artículo científico publicado en 2014

A major role for mammals in the ecology of Mycobacterium ulcerans.

artículo científico publicado en 2010

A nanomechanical study of the effects of colistin on the Klebsiella pneumoniae AJ218 capsule.

artículo científico publicado en 2016

A novel mycolactone from a clinical isolate of Mycobacterium ulcerans provides evidence for additional toxin heterogeneity as a result of specific changes in the modular polyketide synthase

artículo científico publicado en 2005

A novel mycolactone toxin obtained by biosynthetic engineering

artículo científico publicado en 2007

A supervised statistical learning approach for accurate Legionella pneumophila source attribution during outbreaks.

artículo científico publicado en 2017

A sustained hospital outbreak of vancomycin-resistant Enterococcus faecium bacteremia due to emergence of vanB E. faecium sequence type 203.

artículo científico publicado en 2010

Accessible Platform for High-Throughput COVID-19 Molecular Diagnostics and Genome Sequencing Using a Repurposed 3D Printer for RNA Extraction

artículo científico publicado en 2021

Adaptive change inferred from genomic population analysis of the ST93 epidemic clone of community-associated methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2014

Analysis of Rhizonin Biosynthesis Reveals Origin of Pharmacophoric Furylalanine Moieties in Diverse Cyclopeptides

artículo científico publicado en 2023

Analysis of a Novel pncA Mutation for Susceptibility to Pyrazinamide Therapy.

artículo científico publicado en 2018

Analysis of the Mycobacterium ulcerans genome sequence reveals new loci for variable number tandem repeats (VNTR) typing

artículo científico publicado en 2007

Analysis of the small RNA transcriptional response in multidrug-resistant Staphylococcus aureus after antimicrobial exposure

artículo científico publicado en 2013

Analysis of the vaccine potential of plasmid DNA encoding nine mycolactone polyketide synthase domains in Mycobacterium ulcerans infected mice

artículo científico publicado en 2014

Aquatic plants stimulate the growth of and biofilm formation by Mycobacterium ulcerans in axenic culture and harbor these bacteria in the environment

artículo científico publicado en 2004

Bacterial membrane vesicles transport their DNA cargo into host cells.

artículo científico publicado en 2017

Biosynthesis and Ether-Bridge Formation in Nargenicin Macrolides

artículo científico publicado en 2019

Burkholderia lata Infections from Intrinsically Contaminated Chlorhexidine Mouthwash, Australia, 2016

article

Buruli ulcer (M. ulcerans infection): new insights, new hope for disease control

artículo científico publicado en 2005

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

artículo científico publicado en 2009

Buruli ulcers in a Spanish aid worker after a stay in Peru

artículo científico publicado en 2018

Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment

artículo científico publicado en 2019

Changes in protein abundance are observed in bacterial isolates from a natural host

artículo científico publicado en 2015

Comment on: Benchmarking of methods for identification of antimicrobial resistance genes in bacterial whole genome data.

artículo científico publicado en 2016

Common evolutionary origin for the unstable virulence plasmid pMUM found in geographically diverse strains of Mycobacterium ulcerans

artículo científico publicado en 2005

Comparative Transcriptomic and Functional Assessments of Linezolid-Responsive Small RNA Genes in Staphylococcus aureus

artículo científico publicado en 2020

Comparative analysis of the complete genome of an epidemic hospital sequence type 203 clone of vancomycin-resistant Enterococcus faecium

artículo científico publicado en 2013

Comparative genetic analysis of Mycobacterium ulcerans and Mycobacterium marinum reveals evidence of recent divergence

artículo científico publicado en 2000

Comparative genomics shows Mycobacterium ulcerans migration and expansion has preceded the rise of Buruli ulcer in south-eastern Australia.

artículo científico publicado en 2018

Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages.

artículo científico publicado en 2015

Complete genome sequence of Staphylococcus aureus strain JKD6008, an ST239 clone of methicillin-resistant Staphylococcus aureus with intermediate-level vancomycin resistance

artículo científico publicado en 2010

Complete genome sequence of Staphylococcus aureus strain JKD6159, a unique Australian clone of ST93-IV community methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2010

Complete genome sequence of the frog pathogen Mycobacterium ulcerans ecovar Liflandii

artículo científico publicado en 2012

Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)

artículo científico publicado en 2018

Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis

artículo científico publicado en 2008

Convergent Evolution Driven by Rifampin Exacerbates the Global Burden of Drug-Resistant Staphylococcus aureus.

artículo científico publicado en 2018

Convergent adaptation in the dominant global hospital clone ST239 of methicillin-resistant Staphylococcus aureus.

artículo científico publicado en 2015

Correction: Buruli Ulcer (M. ulcerans Infection): New Insights, New Hope for Disease Control

artículo científico publicado en 2005

Correction: Whole Genome Comparisons Suggest Random Distribution of Mycobacterium ulcerans Genotypes in a Buruli Ulcer Endemic Region of Ghana

artículo científico publicado en 2015

Correspondence: Spontaneous secondary mutations confound analysis of the essential two-component system WalKR in Staphylococcus aureus

artículo científico publicado en 2017

Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones

artículo científico publicado en 2008

Decreased vancomycin susceptibility in Staphylococcus aureus caused by IS256 tempering of WalKR expression

artículo científico publicado en 2013

Detection of Mycobacterium ulcerans in environmental samples during an outbreak of ulcerative disease ⬇️

artículo científico publicado el 1 de octubre de 1997

Development and application of two multiplex real-time PCR assays for the detection of Mycobacterium ulcerans in clinical and environmental samples

artículo científico publicado en 2007

Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia

artículo científico publicado en 2008

Dual Gene Expression Analysis Identifies Factors Associated with Staphylococcus aureus Virulence in Diabetic Mice

artículo científico publicado en 2019

Emergence of a ribotype 244 strain of Clostridium difficile associated with severe disease and related to the epidemic ribotype 027 strain

artículo científico publicado en 2014

Emergence of endemic MLST non-typeable vancomycin-resistant Enterococcus faecium

artículo científico publicado en 2016

Emergence of multidrug resistance in locally-acquired human infections with Salmonella Typhimurium in Australia owing to a new clade harbouring blaCTX-M-9.

artículo científico publicado en 2017

Enterococcal vanB resistance locus in anaerobic bacteria in human faeces

artículo científico publicado en 2001

Evaluation of VNTR typing for the identification of Mycobacterium ulcerans in environmental samples from Victoria, Australia

artículo científico publicado en 2008

Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR

artículo científico publicado en 2011

Evolution of two distinct phylogenetic lineages of the emerging human pathogen Mycobacterium ulcerans

artículo científico publicado en 2007

Evolution of virulence in Enterococcus faecium, a hospital-adapted opportunistic pathogen.

artículo científico publicado en 2017

Evolutionary origins of the emergent ST796 clone of vancomycin resistant Enterococcus faecium.

artículo científico publicado en 2017

Exposure Risk for Infection and Lack of Human-to-Human Transmission of Mycobacterium ulcerans Disease, Australia

artículo científico publicado en 2017

First isolation of Mycobacterium ulcerans from an aquatic environment: the end of a 60-year search?

artículo científico publicado en 2008

Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans

artículo científico publicado en 2005

Functional analysis of the first complete genome sequence of a multidrug resistant sequence type 2 Staphylococcus epidermidis.

artículo científico publicado en 2016

Functional genomics of Staphylococcus aureus

artículo científico publicado en 2013

Genome Mining Reveals Endopyrroles from a Nonribosomal Peptide Assembly Line Triggered in Fungal-Bacterial Symbiosis

scientific article published on 22 July 2019

Genome Mining and Heterologous Expression Reveal Two Distinct Families of Lasso Peptides Highly Conserved in Endofungal Bacteria

artículo científico publicado en 2019

Genome comparisons provide insights into the role of secondary metabolites in the pathogenic phase of the Photorhabdus life cycle

artículo científico publicado en 2016

Genomewide Profiling of the Enterococcus faecalis Transcriptional Response to Teixobactin Reveals CroRS as an Essential Regulator of Antimicrobial Tolerance

artículo científico publicado en 2019

Genomic Insights into a Sustained National Outbreak of Yersinia pseudotuberculosis.

artículo científico publicado en 2016

Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana

artículo científico publicado en 2017

Genomic analysis of multi-resistant associated with neonatal sepsis

artículo científico publicado en 2018

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

artículo científico publicado en 2013

Genomic analysis of teicoplanin resistance emerging during treatment of vanB vancomycin-resistant Enterococcus faecium infections in solid organ transplant recipients including donor-derived cases.

artículo científico publicado en 2013

Genomic analysis reveals a point mutation in the two-component sensor gene graS that leads to intermediate vancomycin resistance in clinical Staphylococcus aureus

artículo científico publicado en 2008

Genomic epidemiology and antimicrobial resistance of Neisseria gonorrhoeae in New Zealand.

artículo científico publicado en 2017

Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia

artículo científico publicado en 2018

Genomic insights to control the emergence of vancomycin-resistant enterococci

artículo científico publicado en 2013

Genomic investigation of Staphylococcus aureus recovered from Gambian women and newborns following an oral dose of intra-partum azithromycin

scientific article published on 01 November 2019

Genomics for Molecular Epidemiology and Detecting Transmission of Carbapenemase-Producing Enterobacterales in Victoria, Australia, 2012 to 2016

scientific article published on 26 August 2019

Genomics of vancomycin-resistant Enterococcus faecium

scientific article published on 22 July 2019

Genomics-Driven Discovery of NO-Donating Diazeniumdiolate Siderophores in Diverse Plant-Associated Bacteria ⬇️

scientific article published on 05 August 2019

Genomics‐Driven Discovery of NO‐Donating Diazeniumdiolate Siderophores in Diverse Plant‐Associated Bacteria

artículo científico publicado en 2019

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans ⬇️

artículo científico publicado en 2004

Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia

scientific article published on 21 August 2020

Global spread of three multidrug-resistant lineages of Staphylococcus epidermidis

artículo científico publicado en 2018

Human blood MAIT cell subsets defined using MR1 tetramers.

artículo científico publicado en 2018

Hyperexpression of α-hemolysin explains enhanced virulence of sequence type 93 community-associated methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2014

IFN-γ and IL-5 whole blood response directed against mycolactone polyketide synthase domains in patients with infection

scientific article published on 31 July 2018

Identification and Mobilization of a Cryptic Antibiotic Biosynthesis Gene Locus from a Human-Pathogenic Nocardia Isolate

artículo científico publicado en 2019

Identification of Mycobacterium ulcerans in the environment from regions in Southeast Australia in which it is endemic with sequence capture-PCR.

artículo científico publicado en 2000

Identification of the Mycobacterium ulcerans protein MUL_3720 as a promising target for the development of a diagnostic test for Buruli ulcer

artículo científico publicado en 2015

In Vivo Imaging of Bioluminescent Mycobacterium ulcerans: A Tool to Refine the Murine Buruli Ulcer Tail Model

scientific article published on 01 December 2019

In silico serotyping of E. coli from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.

artículo científico publicado en 2016

In-vitro activity of avermectins against Mycobacterium ulcerans

artículo científico publicado en 2015

Increasing tolerance of hospital Enterococcus faecium to handwash alcohols

artículo científico publicado en 2018

Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis

artículo científico publicado en 2008

Investigating the Role of Free-living Amoebae as a Reservoir for Mycobacterium ulcerans

artículo científico publicado en 2014

Isolates with low-level vancomycin resistance associated with persistent methicillin-resistant Staphylococcus aureus bacteremia

artículo científico publicado en 2006

Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria

scientific article published on 15 August 2016

Lack of insertional-deletional polymorphism in a collection of mycobacterium ulcerans isolates from Ghanaian buruli ulcer patients

artículo científico publicado en 2009

Leprosy in red squirrels.

artículo científico publicado en 2016

Low incidence of recurrent Buruli ulcers in treated Australian patients living in an endemic region

artículo científico publicado en 2018

Low-Cost, Open-Source Device for High-Performance Fluorescence Detection of Isothermal Nucleic Acid Amplification Reactions

artículo científico publicado en 2021

Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease.

artículo científico publicado en 2015

Methicillin Resistant Staphylococcus aureus Transmission in a Ghanaian Burn Unit: The Importance of Active Surveillance in Resource-Limited Settings.

artículo científico publicado en 2017

Microbe-Metabolite Associations Linked to the Rebounding Murine Gut Microbiome Postcolonization with Vancomycin-Resistant Enterococcus faecium

artículo científico publicado en 2020

Mining Symbionts of a Spider-Transmitted Fungus Illuminates Uncharted Biosynthetic Pathways to Cytotoxic Benzolactones ⬇️

artículo científico publicado en 2020

Mining Symbionts of a Spider‐Transmitted Fungus Illuminates Uncharted Biosynthetic Pathways to Cytotoxic Benzolactones

artículo científico publicado en 2020

Mining the Methylome Reveals Extensive Diversity in Staphylococcus epidermidis Restriction Modification

artículo científico publicado en 2019

Molecular epidemiology of enterococcal bacteremia in Australia

artículo científico publicado en 2014

Multiple Introductions and Recent Spread of the Emerging Human Pathogen Mycobacterium ulcerans across Africa ⬇️

artículo científico publicado en 2017

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.

artículo científico publicado en 2014

Mycobacterium chimaera Spread from Heating and Cooling Units in Heart Surgery.

artículo científico publicado en 2017

Mycobacterium ulcerans DNA not detected in faecal samples from Buruli ulcer patients: results of a pilot study

artículo científico publicado en 2011

Mycobacterium ulcerans Population Genomics To Inform on the Spread of Buruli Ulcer across Central Africa

artículo científico publicado en 2019

Mycobacterium ulcerans and other mycolactone-producing mycobacteria should be considered a single species

artículo científico publicado en 2010

Mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer.

artículo científico publicado en 2017

Mycolactones and Mycobacterium ulcerans disease

artículo científico publicado en 2003

Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria

artículo científico publicado en 2008

NGMASTER:in silico multi-antigen sequence typing for Neisseria gonorrhoeae.

artículo científico publicado en 2016

Natural product diversity associated with the nematode symbionts Photorhabdus and Xenorhabdus

artículo científico publicado en 2017

Niche-specific genome degradation and convergent evolution shaping Staphylococcus aureus adaptation during severe infections

artículo científico publicado en 2022

On the origin of mycobacterium ulcerans, the causative agent of buruli ulcer

artículo científico publicado en 2012

Optimising genomic approaches for identifying vancomycin-resistant Enterococcus faecium transmission in healthcare settings

artículo científico publicado en 2022

Outbreak investigation using high-throughput genome sequencing within a diagnostic microbiology laboratory

artículo científico publicado en 2013

Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants

artículo científico publicado en 2009

Population genetics and the evolution of virulence in Staphylococcus aureus

artículo científico

Population genomics provides insights into the evolution and adaptation to humans of the waterborne pathogen Mycobacterium kansasii

artículo científico publicado en 2021

Possible healthcare-associated transmission as a cause of secondary infection and population structure of Staphylococcus aureus isolates from two wound treatment centres in Ghana

scientific article published on 12 July 2016

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering

artículo científico publicado en 2020

Prospective Whole-Genome Sequencing Enhances National Surveillance of Listeria monocytogenes.

artículo científico publicado en 2015

Proteomic characterization of a natural host-pathogen interaction: repertoire of in vivo expressed bacterial and host surface-associated proteins.

artículo científico publicado en 2014

Rapid Emergence and Evolution of Staphylococcus aureus Clones Harboring fusC-Containing Staphylococcal Cassette Chromosome Elements.

artículo científico publicado en 2016

Rapid and sensitive detection of mycobacterium ulcerans by use of a loop-mediated isothermal amplification test

artículo científico publicado en 2012

Reconstruction of the Genomes of Drug-Resistant Pathogens for Outbreak Investigation through Metagenomic Sequencing

scientific article published on 16 January 2019

Reduced vancomycin susceptibility in Staphylococcus aureus, including vancomycin-intermediate and heterogeneous vancomycin-intermediate strains: resistance mechanisms, laboratory detection, and clinical implications

artículo científico publicado en 2010

Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer

artículo científico publicado en 2007

Regulation of mycolactone, the Mycobacterium ulcerans toxin, depends on nutrient source

artículo científico publicado en 2013

Regulation of the 18 kDa heat shock protein in Mycobacterium ulcerans: an alpha-crystallin orthologue that promotes biofilm formation

artículo científico publicado en 2010

Remodelling of pSK1 Family Plasmids and Enhanced Chlorhexidine Tolerance in a Dominant Hospital Lineage of Methicillin-Resistant Staphylococcus aureus

scientific article published on 25 April 2019

Reply to "Internet-based solutions for analysis of next-generation sequence data"

artículo científico publicado en 2013

Serological evaluation of Mycobacterium ulcerans antigens identified by comparative genomics

artículo científico publicado en 2010

Sharing Is Caring: International Sharing of Data Enhances Genomic Surveillance of Listeria monocytogenes.

artículo científico publicado en 2016

Single nucleotide polymorphism typing of mycobacterium ulcerans reveals focal transmission of buruli ulcer in a highly endemic region of Ghana

artículo científico publicado en 2010

Snapshot fecal survey of domestic animals in rural Ghana for Mycobacterium ulcerans

artículo científico publicado en 2016

Staphylococcus aureus induces cell-surface expression of immune stimulatory NKG2D ligands on human monocytes

scientific article published on 30 June 2020

Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66.

artículo científico publicado en 2017

Subtractive hybridization reveals a type I polyketide synthase locus specific to Mycobacterium ulcerans

artículo científico publicado en 2003

Symbiosis, virulence and natural-product biosynthesis in entomopathogenic bacteria are regulated by a small RNA

artículo científico publicado en 2020

Target-Specific Assay for Rapid and Quantitative Detection of Mycobacterium chimaera DNA.

artículo científico publicado en 2017

The First Isolation and Whole Genome Sequencing of Murray Valley Encephalitis Virus from Cerebrospinal Fluid of a Patient with Encephalitis.

artículo científico publicado en 2018

The RpoB H₄₈₁Y rifampicin resistance mutation and an active stringent response reduce virulence and increase resistance to innate immune responses in Staphylococcus aureus

artículo científico publicado en 2012

The cell wall-associated mycolactone polyketide synthases are necessary but not sufficient for mycolactone biosynthesis ⬇️

artículo científico publicado en 2013

The changing landscape of vancomycin-resistant Enterococcus faecium in Australia: a population-level genomic study

article

The evolution of vancomycin intermediate Staphylococcus aureus (VISA) and heterogenous-VISA.

artículo científico publicado en 2013

The genome, evolution and diversity of Mycobacterium ulcerans

artículo científico

The lipoprotein LpqW is essential for the mannosylation of periplasmic glycolipids in Corynebacteria.

artículo científico publicado en 2012

The molecular epidemiology of the highly virulent ST93 Australian community Staphylococcus aureus strain

artículo científico publicado en 2012

The ΦBT1 large serine recombinase catalyzes DNA integration at pseudo-attB sites in the genus Nocardia.

artículo científico publicado en 2018

Topical Antibiotic Use Coselects for the Carriage of Mobile Genetic Elements Conferring Resistance to Unrelated Antimicrobials in Staphylococcus aureus.

artículo científico publicado en 2017

Tracking the COVID-19 pandemic in Australia using genomics

scientific article published on 17 May 2020

Tracking the COVID-19 pandemic in Australia using genomics

artículo científico publicado en 2020

Transfer, stable maintenance and expression of the mycolactone polyketide megasynthase mls genes in a recombination-impaired Mycobacterium marinum

artículo científico publicado en 2009

Translating genomics into practice for real-time surveillance and response to carbapenemase-producing Enterobacteriaceae: evidence from a complex multi-institutional KPC outbreak.

artículo científico publicado en 2018

Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection

artículo científico publicado en 2010

Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infections

artículo científico publicado en 2019

Use of bacterial whole-genome sequencing to understand and improve the management of invasive Staphylococcus aureus infections

artículo científico publicado en 2016

Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model

scientific article published on 20 February 2020

Validation of a single-step, single-tube reverse transcription-loop-mediated isothermal amplification assay for rapid detection of SARS-CoV-2 RNA

scientific article published on 30 April 2020

Vancomycin-intermediate Staphylococcus aureus isolates are attenuated for virulence when compared with susceptible progenitors.

artículo científico publicado en 2017

Vancomycin-resistant Enterococcus faecium sequence type 796 - rapid international dissemination of a new epidemic clone.

artículo científico publicado en 2018

Whole Genome Comparisons Suggest Random Distribution of Mycobacterium ulcerans Genotypes in a Buruli Ulcer Endemic Region of Ghana

artículo científico publicado en 2015

Whole-genome sequencing reveals transmission of gonococcal antibiotic resistance among men who have sex with men: an observational study

artículo científico publicado en 2017

YycH and YycI Regulate Expression of Staphylococcus aureus Autolysins by Activation of WalRK Phosphorylation

artículo científico publicado en 2020

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

scientific article published on 11 July 2019

pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

artículo científico publicado en 2016

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