Lista de obras - Laura Pasqualucci - Dominio Público Uruguay

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

artículo científico publicado en 2007

AID is required for germinal center-derived lymphomagenesis

artículo científico publicado en 2007

Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma

artículo científico publicado en 2003

Aberrant somatic hypermutation in post-transplant lymphoproliferative disorders.

artículo científico publicado en 2004

Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma.

artículo científico publicado en 2006

Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma

artículo científico publicado en 2011

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression

artículo científico publicado en 2015

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

artículo científico publicado en 2011

Analysis of the coding genome of diffuse large B-cell lymphoma

artículo científico publicado en 2011

BCL-6 mutations are associated with immunoglobulin variable heavy chain mutations in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2000

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

artículo científico publicado en 1998

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

artículo científico publicado en 2009

BLIMP1 is a tumor suppressor gene frequently disrupted in activated B cell-like diffuse large B cell lymphoma

artículo científico publicado en 2010

BRAF mutations in hairy-cell leukemia

artículo científico publicado en 2011

Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

artículo científico publicado en 2006

Combined genetic inactivation of β2-Microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphoma

artículo científico publicado en 2011

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

artículo científico publicado en 2005

Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia

artículo científico publicado en 2012

Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.

artículo científico publicado en 2015

Emerging epigenetic-modulating therapies in lymphoma

artículo científico publicado en 2019

Expression of the AID protein in normal and neoplastic B cells

artículo científico publicado en 2004

Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT).

artículo científico publicado en 2003

Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015.

artículo científico publicado en 2017

Fractal-like distributions over the rational numbers in high-throughput biological and clinical data

artículo científico publicado en 2011

Genetic and phenotypic analysis of B-cell post-transplant lymphoproliferative disorders provides insights into disease biology

artículo científico publicado en 2008

Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas

artículo científico publicado en 2016

Genetic drivers of NF-κB deregulation in diffuse large B-cell lymphoma

artículo científico publicado en 2016

Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness

scientific article published on 18 February 2014

Genetics of diffuse large B cell lymphoma

artículo científico publicado en 2018

Genetics of follicular lymphoma transformation

artículo científico publicado en 2014

Genomic analysis of non-splenic marginal zone lymphomas (MZL) indicates similarities between nodal and extranodal MZL and supports their derivation from memory B-cells

artículo científico publicado en 2011

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

artículo científico publicado en 2001

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

artículo científico publicado en 2011

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

artículo científico publicado en 2006

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

artículo científico publicado en 2013

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

artículo científico publicado en 2012

MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis

artículo científico publicado en 2018

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma

artículo científico publicado en 2013

Molecular pathogenesis of germinal center-derived B cell lymphomas

artículo científico publicado en 2019

Molecular pathogenesis of non-Hodgkin's lymphoma: the role of Bcl-6

artículo científico publicado en 2003

MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples

artículo científico publicado en 2013

Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification

artículo científico publicado en 2006

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

artículo científico publicado en 2012

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma

artículo científico publicado en 2002

Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness

artículo científico publicado en 2011

On statistical modeling of sequencing noise in high depth data to assess tumor evolution

article by Raúl Rabadán et al published July 2018 in Journal of Statistical Physics

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

artículo científico publicado en 2005

SAVI: a statistical algorithm for variant frequency identification

artículo científico publicado en 2013

Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

artículo científico publicado en 2011

SnapShot: diffuse large B cell lymphoma

artículo científico publicado en 2014

Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity

artículo científico publicado en 2017

Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation

artículo científico publicado en 2009

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition

artículo científico publicado en 2017

The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma

artículo científico publicado en 2017

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development

artículo científico publicado en 2012

The genetic landscape of diffuse large B-cell lymphoma

artículo científico publicado en 2015

Towards patient-based cancer therapeutics

artículo científico publicado en 2010

Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia

artículo científico publicado en 2014

Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype

artículo científico publicado en 2011

Lista de obras de Laura Pasqualucci

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

AID is required for germinal center-derived lymphomagenesis

Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma

Aberrant somatic hypermutation in post-transplant lymphoproliferative disorders.

Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma.

Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

Analysis of the coding genome of diffuse large B-cell lymphoma

BCL-6 mutations are associated with immunoglobulin variable heavy chain mutations in B-cell chronic lymphocytic leukemia

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

BLIMP1 is a tumor suppressor gene frequently disrupted in activated B cell-like diffuse large B cell lymphoma

BRAF mutations in hairy-cell leukemia

Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

Combined genetic inactivation of β2-Microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphoma

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia

Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.

Emerging epigenetic-modulating therapies in lymphoma

Expression of the AID protein in normal and neoplastic B cells

Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT).

Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015.

Fractal-like distributions over the rational numbers in high-throughput biological and clinical data

Genetic and phenotypic analysis of B-cell post-transplant lymphoproliferative disorders provides insights into disease biology

Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas

Genetic drivers of NF-κB deregulation in diffuse large B-cell lymphoma

Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness

Genetics of diffuse large B cell lymphoma

Genetics of follicular lymphoma transformation

Genomic analysis of non-splenic marginal zone lymphomas (MZL) indicates similarities between nodal and extranodal MZL and supports their derivation from memory B-cells

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma

Molecular pathogenesis of germinal center-derived B cell lymphomas

Molecular pathogenesis of non-Hodgkin's lymphoma: the role of Bcl-6

MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples

Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma

Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness

On statistical modeling of sequencing noise in high depth data to assess tumor evolution

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

SAVI: a statistical algorithm for variant frequency identification

Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

SnapShot: diffuse large B cell lymphoma

Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity

Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition

The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development

The genetic landscape of diffuse large B-cell lymphoma

Towards patient-based cancer therapeutics

Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia

Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype