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Lista de obras de Pierre Fenaux

17p Deletion in acute myeloid leukemia and myelodysplastic syndrome. Analysis of breakpoints and deleted segments by fluorescence in situ

artículo científico publicado en 1998

A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS

artículo científico publicado el 16 de febrero de 2011

A G polymorphism in the CRBN gene acts as a biomarker of response to treatment with lenalidomide in low/int-1 risk MDS without del(5q).

artículo científico publicado en 2013

A controlled study of recombinant human granulocyte colony-stimulating factor in elderly patients after treatment for acute myelogenous leukemia. AML Cooperative Study Group

artículo científico publicado en 1995

A cost-effectiveness analysis of using azacitidine vs. decitabine in treating patients with myelodysplastic syndromes

artículo científico publicado en 2011

A decade of progress in myelodysplastic syndrome with chromosome 5q deletion

artículo científico publicado en 2018

A landscape of germline mutations in a cohort of inherited bone marrow failure patients

artículo científico publicado en 2017

A multicenter phase 2 study of the farnesyltransferase inhibitor tipifarnib in intermediate- to high-risk myelodysplastic syndrome

artículo científico publicado en 2007

A multivariate analysis of the relationship between response and survival among patients with higher-risk myelodysplastic syndromes treated within azacitidine or conventional care regimens in the randomized AZA-001 trial

artículo científico publicado en 2013

A new case of dic(9;12)(p13;p11) in acute lymphocytic leukemia

scientific article published on 01 October 1989

A new variant t(6;15;17)(q25;q22;q21) in acute promyelocytic leukemia: fluorescence in situ hybridization confirmation.

artículo científico

A non-randomised dose-escalating phase II study of thalidomide for the treatment of patients with low-risk myelodysplastic syndromes: the Thal-SMD-2000 trial of the Groupe Français des Myélodysplasies

artículo científico publicado en 2005

A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts

artículo científico publicado en 2008

A phase 1b/2b multicenter study of oral panobinostat plus azacitidine in adults with MDS, CMML or AML with ⩽30% blasts.

artículo científico publicado en 2017

A phase 2 study of the oral farnesyltransferase inhibitor tipifarnib in patients with refractory or relapsed acute myeloid leukemia.

artículo científico publicado en 2007

A phase 3 randomized, placebo-controlled study assessing the efficacy and safety of epoetin-α in anemic patients with low-risk MDS

scientific article published on 30 March 2018

A phase I/II trial of Erlotinib in higher risk myelodysplastic syndromes and acute myeloid leukemia after azacitidine failure

artículo científico publicado en 2014

A phase II study of guadecitabine in higher-risk myelodysplastic syndrome and low blast count acute myeloid leukemia after azacitidine failure

artículo científico publicado en 2019

A phase II study of intensive chemotherapy with fludarabine, cytarabine, and mitoxantrone in P glycoprotein-negative high-risk myelodysplastic syndromes

artículo científico publicado en 2004

A phase II study of the efficacy and safety of an intensified schedule of azacitidine in intermediate-2 and high risk patients with myelodysplastic syndromes: a study by the Groupe Francophone des myelodysplasies (GFM)

scholarly article by Lionel Ades et al published 31 October 2018 in Haematologica

A phase II trial of induction and consolidation therapy of acute myeloid leukemia with weekly oral idarubicin alone in poor risk elderly patients

artículo científico publicado en 1999

A prospective study of autologous bone marrow or peripheral blood stem cell transplantation after intensive chemotherapy in myelodysplastic syndromes

artículo científico publicado en 1999

A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group

artículo científico publicado en 1999

A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q

artículo científico publicado en 2011

A randomized phase II trial of azacitidine +/- epoetin-β in lower-risk myelodysplastic syndromes resistant to erythropoietic stimulating agents

artículo científico

A randomized trial comparing vinblastine in slow infusion and by bolus i.v. injection in idiopathic thrombocytopenic purpura: a report on 42 patients

artículo científico publicado en 1994

A randomized trial of amsacrine and rubidazone in 39 patients with acute promyelocytic leukemia

artículo científico publicado el 1 de septiembre de 1991

A randomized trial of hydroxyurea versus VP16 in adult chronic myelomonocytic leukemia. Groupe Français des Myélodysplasies and European CMML Group

artículo científico publicado en 1996

A randomized, double-blind, placebo-controlled study with pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) as an adjunct to chemotherapy for adults with de novo acute myeloid leukemia

article

A white blood cell index as the main prognostic factor in t(8;21) acute myeloid leukemia (AML): a survey of 161 cases from the French AML Intergroup

artículo científico publicado en 2002

ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia

artículo científico publicado en 2008

Absence of BCR-ABL rearrangement (with m-bcr breakpoint) in chronic myelomonocytic leukemia

scientific article published on 01 October 1994

Absence of amplification of MDM2 gene, a regulator of p53 function, in myelodysplastic syndromes

artículo científico publicado en 1993

Absence of germline mutations of exons 5 to 8 of the P53 gene in 26 breast cancer families from the north of France

artículo científico publicado en 1993

Absence of rearrangement of proto-oncogene MET in 88 cases of myelodysplastic syndromes (MDS).

artículo científico publicado en 1989

Absence of rearrangement of the neurofibromatosis 1 (NF1) gene in myelodysplastic syndromes and acute myeloid leukemia

scientific article published on 01 May 1994

Absence of somatic mutations within the Runt domain of AML2/RUNX3 in acute myeloid leukaemia

scientific article published on 01 August 2003

Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia

artículo científico publicado en 2019

Accessory spleen in recurrent chronic immune thrombocytopenic purpura

artículo científico publicado el 1 de noviembre de 1992

Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML.

artículo científico publicado en 2017

Achievement of red blood cell transfusion independence in red blood cell transfusion-dependent patients with lower-risk non-del(5q) myelodysplastic syndromes correlates with serum erythropoietin levels

scientific article published on 17 February 2020

Acquired idiopathic sideroblastic anemia. Apropos of 39 cases

artículo científico publicado en 1989

Acquired trisomy 21 and distinct clonal evolution in acute megakaryoblastic leukaemia in young monozygotic twins

scientific article published on 01 September 2002

Activation of cytotoxic T-cell receptor gammadelta T lymphocytes in response to specific stimulation in myelodysplastic syndromes.

artículo científico publicado en 2008

Acute Promyelocytic Leukemia in Children: a Report on Eleven Cases

artículo científico publicado en 1990

Acute colonic pseudo-obstruction (Ogilvie's syndrome) during induction treatment with chemotherapy and all-trans-retinoic acid for acute promyelocytic leukemia

artículo científico publicado en 1995

Acute lymphocytic leukemia with 9p anomalies. A report of four additional cases and review of the literature

artículo científico publicado en 1988

Acute monocytic leukaemia in adults: treatment and prognosis in 99 cases

artículo científico publicado en 1990

Acute monocytic leukemia with (8;22)(p11;q13) translocation. Involvement of 8p11 as in classical t(8;16)(p11;p13)

artículo científico publicado en 1992

Acute myeloblastic leukemia (AML) with inv (16)(p13;q22) and the rare I type CBFbeta-MYH11 transcript: report of two new cases

artículo científico publicado en 2002

Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: high proportion of cases with 17p deletion.

artículo científico publicado en 1998

Acute promyelocytic leukemia: biology and treatment

artículo científico publicado en 1997

Addition of suberoylanilide hydroxamic acid (Vorinostat) to azacitidine for patients with higher risk myelodysplastic syndromes and azacitidine failure: a phase II add-on study from the Groupe Francophone des Myelodysplasies

artículo científico publicado en 2016

Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial

Additional prognostic impact of the percentage of erythroid cells in the bone marrow of patients with myelodysplastic syndromes

scientific article published on 28 December 2018

Aggressive chemotherapy in adult primary myelodysplastic syndromes. A report on 29 cases

artículo científico publicado en 1988

All trans retinoic acid in acute promyelocytic leukemia

scientific article published on 01 January 1991

All trans retinoic acid treatment for patients with acute promyelocytic leukemia.

artículo científico publicado en 1992

All-trans retinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia

artículo científico publicado en 2001

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results

artículo científico publicado en 1990

All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship.

artículo científico publicado en 1990

All-trans retinoic acid in adult chronic myelomonocytic leukemia: results of a pilot study.

artículo científico publicado en 1996

All-trans retinoic acid pharmacokinetics and bioavailability in acute promyelocytic leukemia: intracellular concentrations and biologic response relationship.

artículo científico publicado en 1995

All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia.

artículo científico publicado en 1995

All-transretinoic acid followed by intensive chemotherapy gives a high complete remission rate and may prolong remissions in newly diagnosed acute promyelocytic leukemia: a pilot study on 26 cases

artículo científico publicado el 1 de noviembre de 1992

Allogeneic bone marrow transplantation in patients with follicular lymphoma: a single center study

scientific article published on 01 August 2002

Allogeneic hematopoietic cell transplantation following the use of hypomethylating agents among patients with relapsed or refractory AML: Findings from an international retrospective study.

artículo científico publicado en 2018

Allogeneic hematopoietic cell transplantation in patients age 60-70 years with de novo high-risk myelodysplastic syndrome or secondary acute myelogenous leukemia: comparison with patients lacking donors who received azacitidine

artículo científico publicado en 2012

Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel

artículo científico publicado en 2017

Allogeneic stem cell transplantation for chronic myelomonocytic leukemia: a report from the Societe Francaise de Greffe de Moelle et de Therapie Cellulaire

artículo científico publicado en 2013

Allogeneic stem cell transplantation in second rather than first complete remission in selected patients with good-risk acute myeloid leukemia.

artículo científico publicado en 2005

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

artículo científico publicado en 2009

An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms.

artículo científico publicado en 2015

An exploratory phase 2 study of investigational Aurora A kinase inhibitor alisertib (MLN8237) in acute myelogenous leukemia and myelodysplastic syndromes

artículo científico publicado en 2014

An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults

artículo científico publicado en 2015

An international data set for CMML validates prognostic scoring systems and demonstrates a need for novel prognostication strategies.

artículo científico publicado en 2015

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia

artículo científico publicado en 2016

Analysis of p16 gene deletion and point mutation in breast carcinoma

artículo científico publicado en 1995

Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface

article

Androgen therapy in myelodysplastic syndromes with thrombocytopenia: a report on 20 cases

artículo científico publicado en 1994

Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia

artículo científico publicado en 2011

Are PU.1 mutations frequent genetic events in acute myeloid leukemia (AML)?

artículo científico publicado en 2002

Are myelodysplastic syndromes and acute myeloid leukaemia occurring during the course of lymphoma always therapy related?

artículo científico publicado en 2016

Are somatic mutations predictive of response to erythropoiesis stimulating agents in lower risk myelodysplastic syndromes?

artículo científico publicado en 2016

Arsenic trioxide in patients with myelodysplastic syndromes: a phase II multicenter study

scientific article published on 01 May 2006

Arsenic trioxide in the treatment of acute promyelocytic leukemia. A review of current evidence

artículo científico publicado en 2005

Arsenic trioxide is required in the treatment of newly diagnosed acute promyelocytic leukemia. Analysis of a randomized trial (APL 2006) by the French Belgian Swiss APL group

article

Arsenic trioxide-based therapy of relapsed acute promyelocytic leukemia: registry results from the European LeukemiaNet

artículo científico publicado en 2015

Aseptic muscular abscesses associated with myelodysplastic syndrome

scientific article published on 01 November 2014

Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study.

artículo científico publicado en 2018

Association between health literacy, communication and psychological distress among myelodysplastic syndromes patients

scientific article published on 05 September 2018

Association between myelodysplastic syndromes and inflammatory bowel diseases. Report of seven new cases and review of the literature

artículo científico publicado en 1997

Association of myelodysplastic syndrome and relapsing polychondritis: further evidence.

artículo científico publicado en 1995

Auer rods and differentiation in acute promyelocytic leukemia

Autoantibodies in myelodysplastic syndromes and chronic myelomonocytic leukemia

artículo científico publicado en 2019

Autoimmune and inflammatory diseases associated with chronic myelomonocytic leukemia: A series of 26 cases and literature review

artículo científico publicado en 2016

Autoimmune manifestations associated with myelodysplastic syndromes

scientific article published on 08 August 2018

Autologous and allogeneic stem-cell transplantation as salvage treatment of acute promyelocytic leukemia initially treated with all-trans-retinoic acid: a retrospective analysis of the European acute promyelocytic leukemia group

artículo científico publicado en 2004

Autologous bone marrow transplantation with marrow purged by mafosfamide in seven patients with myelodysplastic syndromes in transformation (AML-MDS): a pilot study

artículo científico publicado en 1993

Autologous or allogeneic stem cell transplantation as post-remission therapy in refractory or relapsed acute myeloid leukemia after highly intensive chemotherapy

artículo científico publicado en 2005

Autologous stem-cell transplantation for non-Hodgkin's lymphomas: the role of graft purging and radiotherapy posttransplantation--results of a retrospective analysis on 120 patients autografted in a single institution.

artículo científico publicado en 1998

Awareness of acute myeloid leukaemia risk induced by diagnosis of a myelodysplastic syndrome

artículo científico publicado en 2016

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

scientific article published on 01 August 2020

Azacitidine for the treatment of relapsed and refractory AML in older patients.

artículo científico publicado en 2014

Azacitidine frontline therapy for unfit acute myeloid leukemia patients: clinical use and outcome prediction

artículo científico publicado en 2014

Azacitidine improves outcome in higher-risk MDS patients with chromosome 7 abnormalities: a retrospective comparison of GESMD and GFM registries.

artículo científico publicado en 2018

Azacitidine in adult patients with acute myeloid leukemia

artículo científico

Azacitidine in patients older than 80 years with acute myeloid leukaemia or myelodysplastic syndromes: a report on 115 patients

scientific article published on 11 May 2020

Azacitidine in the treatment of therapy related myelodysplastic syndrome and acute myeloid leukemia (tMDS/AML): a report on 54 patients by the Groupe Francophone Des Myelodysplasies (GFM).

artículo científico publicado en 2013

Azacitidine in untreated acute myeloid leukemia: a report on 149 patients

artículo científico publicado en 2014

Azacitidine prolongs overall survival and reduces infections and hospitalizations in patients with WHO-defined acute myeloid leukaemia compared with conventional care regimens: an update

artículo científico publicado en 2008

Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia

artículo científico publicado en 2009

Azacitidine treatment for patients with myelodysplastic syndrome and acute myeloid leukemia with chromosome 3q abnormalities

artículo científico publicado en 2015

Azacitidine with or without eltrombopag for first-line treatment of intermediate- or high-risk MDS with thrombocytopenia

scholarly article by Michael Dickinson et al published 10 October 2018 in Blood

Azacytidine and erlotinib exert synergistic effects against acute myeloid leukemia

artículo científico publicado en 2012

B-cell chronic lymphocytic leukemia: present status and future directions. French Cooperative Group on CLL.

artículo científico publicado en 1991

BCL-2 and Mutant NRAS Interact Physically and Functionally in a Mouse Model of Progressive Myelodysplasia

artículo científico publicado en 2007

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

scientific article published on 13 August 2013

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

artículo científico publicado en 2017

Biologics in myelodysplastic syndrome-related systemic inflammatory and autoimmune diseases: French multicenter retrospective study of 29 patients

artículo científico

Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia

scientific article published on 20 March 2019

Biology and treatment of acute promyelocytic leukemia.

artículo científico publicado en 1996

Bone marrow hypocellularity does not affect tolerance or efficacy of azacitidine in patients with higher-risk myelodysplastic syndromes

artículo científico publicado en 2014

Bortezomib combined with low-dose cytarabine in Intermediate-2 and high risk myelodysplastic syndromes. A phase I/II Study by the GFM.

artículo científico publicado en 2012

Burkitt cell acute leukaemia (L3 ALL) in adults: a report of 18 cases

artículo científico publicado en 1989

Burkitt's acute lymphocytic leukemia (L3ALL) in adults

artículo científico publicado en 2001

CEBPA point mutations in hematological malignancies

artículo científico publicado en 2005

CSNK1A1 mutations and gene expression analysis in myelodysplastic syndromes with del(5q).

artículo científico publicado en 2015

Can the revised IPSS predict response to erythropoietic-stimulating agents in patients with classical IPSS low or intermediate-1 MDS?

artículo científico publicado en 2013

Cardiac failure in patients treated with azacitidine, a pyrimidine analogue: Case reports and disproportionality analyses in Vigibase

artículo científico publicado en 2020

Cardiac iron overload assessed by T2* magnetic resonance imaging and cardiac function in regularly transfused myelodysplastic syndrome patients

artículo científico publicado en 2013

Cardiac iron overload assessed by T2* magnetic resonance imaging and cardiac function in regularly transfused myelodysplastic syndrome patients, the GFM experience: response to Bowen et al.

artículo científico publicado en 2013

Challenges of phase III trial design for novel treatments in diseases with no standard treatment: the AZA-001 myelodysplasia study model.

artículo científico publicado en 2013

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia

artículo científico publicado en 2015

Characteristics and outcome of myelodysplastic syndromes (MDS) with isolated 20q deletion: a report on 62 cases

scientific article published on 10 March 2011

Chronic and subacute myelomonocytic leukaemia in the adult: a report of 60 cases with special reference to prognostic factors

artículo científico publicado en 1987

Chronic myelogenous leukemia with t(9;22) and t(8;11): a new chromosome anomaly.

artículo científico publicado en 1987

Chronic myeloid leukemia with unusual variant Ph translocation (22;22)(q11;q13). Two cases with chimeric BCR-ABL transcripts

scientific article published on 01 September 1990

Chronic myelomonocytic leukemia: from biology to therapy

artículo científico publicado en 1997

Chronic myelomonocytic leukemia: myelodysplastic or myeloproliferative?

artículo científico publicado en 2013

Cigarette smoking, alcohol drinking, and risk of lymphoid neoplasms: results of a French case-control study

artículo científico publicado en 2008

Classification of myeloproliferative disorders in the JAK2 era: is there a role for red cell mass?

artículo científico publicado en 2007

Clinical Benefit-Risk Profile of Lenalidomide in Patients With Lower-risk Myelodysplastic Syndromes Without del(5q): Results of a Phase III Trial

scientific article published on 21 December 2018

Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study.

artículo científico publicado en 2017

Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q).

artículo científico publicado en 2017

Clinical course of essential thrombocythemia in 147 cases

artículo científico publicado en 1990

Clinical effectiveness and safety of erythropoietin-stimulating agents for the treatment of low- and intermediate-1-risk myelodysplastic syndrome: a systematic literature review

artículo científico publicado en 2018

Clonal architecture of chronic myelomonocytic leukemias

artículo científico publicado en 2013

Clonal dominance is an adverse prognostic factor in acute myeloid leukemia treated with intensive chemotherapy

artículo científico publicado en 2020

Combination of vorinostat and low dose cytarabine for patients with azacitidine-refractory/relapsed high risk myelodysplastic syndromes

artículo científico publicado en 2013

Combined immunophenotyping and in situ hybridization (FICTION): a rapid method to study cell lineage involvement in myelodysplastic syndromes

scientific article published on 01 July 1995

Comparison of TP53 mutations screening by functional assay of separated allele in yeast and next-generation sequencing in myelodysplastic syndromes

artículo científico publicado en 2015

Comparison of high-dose cytarabine and timed-sequential chemotherapy as consolidation for younger adults with AML in first remission: the ALFA-9802 study

artículo científico publicado en 2011

Congenital diserythropoietic anemia type I. Report on monozygotic twins with associated hemochromatosis and short stature

scientific article published on 01 October 1990

Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes

artículo científico publicado en 2011

Cooperating gene mutations in acute myeloid leukemia: a review of the literature.

artículo científico publicado en 2008

Cooperation of activating Ras/rtk signal transduction pathway mutations and inactivating myeloid differentiation gene mutations in M0 AML: a study of 45 patients

artículo científico publicado en 2006

Correction for Cassinat et al., "New Role for Granulocyte Colony-Stimulating Factor-Induced Extracellular Signal-Regulated Kinase 1/2 in Histone Modification and Retinoic Acid Receptor α Recruitment to Gene Promoters: Relevance to Acute Promyelocyti

artículo científico publicado en 2017

Cutaneous granulocytic sarcoma arising at the site of radiotherapy for breast carcinoma

scientific article published on 01 May 2001

Cutaneous sclerosis, aplastic anemia, and antithymocyte globulin

scientific article published on 01 April 1989

Cytogenetic abnormalities in Tunisian de novo myelodysplastic syndrome: a comparison with other populations

artículo científico publicado en 2008

Cytogenetic analysis has strong independent prognostic value in de novo myelodysplastic syndromes and can be incorporated in a new scoring system: a report on 408 cases

artículo científico publicado en 1993

Cytogenetic and molecular remission in a case of acute myeloid leukaemia(AML) with inversion of chromosome 16 (Inv(16)) and Philadelphia chromosome (Ph)

scientific article published on 01 November 1992

Cytogenetic follow-up by karyotyping and fluorescence in situ hybridization: implications for monitoring patients with myelodysplastic syndrome and deletion 5q treated with lenalidomide

artículo científico publicado el 25 de noviembre de 2010

Cytogenetic studies and their prognostic significance in agnogenic myeloid metaplasia: a report on 47 cases

artículo científico publicado el 1 de septiembre de 1988

Cytogenetic studies in 30 patients with Burkitt's lymphoma or L3 acute lymphoblastic leukemia with special reference to additional chromosome abnormalities

scientific article published on 01 January 1989

Cytogenetics and their prognostic value in childhood and adult acute lymphoblastic leukemia (ALL) excluding L3

artículo científico publicado en 1989

Cytogenetics and their prognostic value in de novo acute myeloid leukaemia: a report on 283 cases

scientific article published on 01 September 1989

Cytogenetics are a predictive factor of response to low dose Ara-C in acute myelogenous leukemia (AML) in the elderly

artículo científico publicado en 1990

Cytogenetics of myelodysplastic syndromes

artículo científico publicado en 1996

Cytological and ultrastructural assessment of free crystals or precipitates associated with pseudoleukocytosis and pseudothrombocytosis in cryoglobulinemia

artículo científico publicado en 1989

Cytolytic function and survival of natural killer cells are severely altered in myelodysplastic syndromes

artículo científico publicado en 2006

Cytomorphology review of 100 newly diagnosed lower-risk MDS patients in the European LeukemiaNet MDS (EUMDS) registry reveals a high inter-observer concordance

artículo científico publicado en 2017

Cytopenia levels for aiding establishment of the diagnosis of myelodysplastic syndromes

artículo científico publicado en 2016

DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

artículo científico publicado en 2005

DNA-mediated adjuvant immunotherapy extends survival in two different mouse models of myeloid malignancies

artículo científico publicado en 2015

Daily practice management of myelodysplastic syndromes in France: data from 907 patients in a one-week cross-sectional study by the Groupe Francophone des Myelodysplasies

artículo científico publicado en 2009

Darbepoetin alfa in anemia of myelodysplastic syndromes: present and beyond

artículo científico publicado en 2010

De novo myelodysplastic syndrome (MDS) with deletion of the long arm of chromosome 20: a subtype of MDS with distinct hematological and prognostic features?

artículo científico publicado en 1993

Defects of immune surveillance offer new insights into the pathophysiology and therapy of myelodysplastic syndromes

artículo científico publicado en 2007

Deferasirox in iron-overloaded patients with transfusion-dependent myelodysplastic syndromes: Results from the large 1-year EPIC study

artículo científico publicado en 2010

Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a 'real time' quantitative RT-PCR assay

artículo científico publicado en 1999

Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using an in situ RT-PCR assay

artículo científico publicado en 1999

Detection of minimal residual disease in chronic myeloid leukemia patients after bone marrow transplantation by polymerase chain reaction

artículo científico publicado en 1990

Detection of p53 mutations in hematological malignancies: comparison between immunocytochemistry and DNA analysis.

artículo científico publicado en 1994

Detection of serum anti p53 antibodies and their correlation with p53 mutations in myelodysplastic syndromes and acute myeloid leukemia

scientific article published on 01 September 1994

Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes

artículo científico publicado en 2014

Development of a core outcome set for myelodysplastic syndromes - a Delphi study from the EUMDS Registry Group

artículo científico publicado en 2020

Diagnosis and Treatment of Chronic Myelomonocytic Leukemias in Adults: Recommendations From the European Hematology Association and the European LeukemiaNet

artículo científico publicado en 2018

Diagnosis and classification of myelodysplastic syndrome: International Working Group on Morphology of myelodysplastic syndrome (IWGM-MDS) consensus proposals for the definition and enumeration of myeloblasts and ring sideroblasts

artículo científico publicado en 2008

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

artículo científico publicado en 2016

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

artículo científico publicado en 2009

Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet

artículo científico publicado en 2013

Diagnosis, classification, and cytogenetics of myelodysplastic syndromes.

artículo científico publicado en 1998

Differential efficacy of adenoviral mediated gene transfer into cells from hematological cell lines and fresh hematological malignancies.

artículo científico publicado en 1996

Differentiating megakaryocytes in myelodysplastic syndromes succumb to mitochondrial derangement without caspase activation

artículo científico publicado en 2007

Differentiation Therapy for Acute Promyelocytic Leukemia

artículo científico publicado el 9 de octubre de 1997

Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS

scientific article published on 06 September 2018

Disappearance of slan-positive non-classical monocytes for diagnosis of chronic myelomonocytic leukemia with associated inflammatory state

scientific article published on 14 August 2019

Disclosure of myelodysplastic syndrome diagnosis: improving patients' understanding and experience

artículo científico publicado en 2013

Distinct mutational pattern of myelodysplastic syndromes with and without 5q- treated with lenalidomide

artículo científico publicado en 2020

Does iron chelation therapy improve survival in regularly transfused lower risk MDS patients? A multicenter study by the GFM (Groupe Francophone des Myélodysplasies).

artículo científico publicado en 2010

Dosage and efficacy of antilymphocyte serum in severe bone marrow aplasia

artículo científico publicado en 1986

Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia.

artículo científico publicado en 2018

Dyserythropoiesis evaluated by RED score and hepcidin/ferritin levels predicts response to erythropoietin in lower risk myelodysplastic syndromes

scientific article published on 04 October 2018

Dysmyelopoeisis

artículo científico publicado en 2005

EGFR inhibitors exacerbate differentiation and cell cycle arrest induced by retinoic acid and vitamin D3 in acute myeloid leukemia cells

artículo científico publicado en 2013

Early death in acute promyelocytic leukemia (APL) in French centers: a multicenter study in 399 patients

artículo científico publicado en 2014

Early introduction of ESA in low risk MDS patients may delay the need for RBC transfusion: a retrospective analysis on 112 patients

artículo científico publicado en 2010

Early locoregional high-dose radiotherapy is associated with long-term disease control in localized primary angiocentric lymphoma of the nose and nasopharynx

artículo científico publicado en 2001

Early onset of chemotherapy can reduce the incidence of ATRA syndrome in newly diagnosed acute promyelocytic leukemia (APL) with low white blood cell counts: results from APL 93 trial

artículo científico publicado en 2003

Early paternity and relapse after bone marrow transplantation

scientific article published on 01 February 1993

Early platelet count kinetics has prognostic value in lower-risk myelodysplastic syndromes

Effect of all transretinoic acid in newly diagnosed acute promyelocytic leukemia. Results of a multicenter randomized trial. European APL 91 Group

artículo científico publicado en 1993

Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study

artículo científico publicado en 2012

Effect of lenalidomide treatment on clonal architecture of myelodysplastic syndromes without 5q deletion

artículo científico publicado en 2015

Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group.

artículo científico publicado en 2007

Effectiveness and tolerance of low to very low dose thalidomide in low-risk myelodysplastic syndromes.

artículo científico publicado en 2008

Effects of azacitidine compared with conventional care regimens in elderly (≥ 75 years) patients with higher-risk myelodysplastic syndromes

artículo científico publicado en 2010

Efficacy and safety of darbepoetin alpha in patients with myelodysplastic syndromes: a systematic review and meta-analysis

artículo científico publicado en 2016

Efficacy and safety of lenalidomide in intermediate-2 or high-risk myelodysplastic syndromes with 5q deletion: results of a phase 2 study

artículo científico publicado en 2008

Efficacy of Azacitidine in autoimmune and inflammatory disorders associated with myelodysplastic syndromes and chronic myelomonocytic leukemia.

artículo científico publicado en 2016

Efficacy of lenalidomide in an sAML patient with del 5q relapsing after reduced-intensity allogeneic stem cell transplantation performed in complete remission

artículo científico publicado en 2009

Efficacy of tocilizumab in rituximab-refractory cryoglobulinemia vasculitis

scientific article published on 25 November 2011

Elevated serum levels of soluble interleukin-2 receptor: a marker of disease activity in the hypereosinophilic syndrome

artículo científico publicado el 15 de noviembre de 1991

Eltrombopag versus placebo for low-risk myelodysplastic syndromes with thrombocytopenia (EQoL-MDS): phase 1 results of a single-blind, randomised, controlled, phase 2 superiority trial

artículo científico publicado en 2017

Epigenetics of myelodysplastic syndromes

artículo científico publicado en 2013

Erdheim-Chester disease associated with chronic myelomonocytic leukemia harboring the same clonal mutation

scientific article published on 20 June 2019

Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparison

artículo científico publicado en 2008

Erlotinib antagonizes ABC transporters in acute myeloid leukemia

artículo científico publicado en 2012

Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia.

artículo científico publicado en 2011

Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study

artículo científico publicado en 2007

Erratum to: Flt3 receptor inhibition reduces constitutive NFκB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia

scientific article published on 01 December 2015

Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome.

artículo científico publicado en 2016

Essential thrombocythemias without V617F JAK2 mutation are clonal hematopoietic stem cell disorders

artículo científico publicado en 2006

Established practice in the treatment of patients with acute promyleocytic leukemia and the introduction of arsenic trioxide as a novel therapy

artículo científico publicado en 2002

Evaluation of induction chemotherapies after hypomethylating agent failure in myelodysplastic syndromes and acute myeloid leukemia

article published in 2018

Evolving characteristics and outcome of secondary acute promyelocytic leukemia (APL): A prospective analysis by the French-Belgian-Swiss APL group.

artículo científico publicado en 2015

Evolving trends in the treatment of low-risk myelodysplastic syndromes: immunomodulation and beyond--9th European Hematology Association Congress Geneva, Switzerland, 10-13 June 2004

artículo científico publicado en 2007

Exome analysis of treatment-related AML after APL suggests secondary evolution

scientific article published on 22 November 2018

Expression level and differential JAK2-V617F-binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms.

artículo científico publicado en 2010

Expression of lung resistance protein and correlation with other drug resistance proteins and outcome in myelodysplastic syndromes.

artículo científico publicado en 1998

Expression of the interleukin 6 gene in acute myeloid leukemia and myelodysplastic syndromes: a report on 49 cases

artículo científico publicado en 1990

Expression of the multidrug resistance P glycoprotein in newly diagnosed adult acute lymphoblastic leukemia: absence of correlation with response to treatment

scientific article published on 01 November 1995

Expression of the multidrug resistance P-glycoprotein and its relationship to hematological characteristics and response to treatment in myelodysplastic syndromes.

artículo científico publicado en 1994

Expression of the multidrug resistance-associated protein in myelodysplastic syndromes

artículo científico publicado en 2000

Extramedullary blastic transformation revealed by a prolonged fever during the course of a 5q- syndrome

artículo científico publicado en 2009

Extramedullary relapse in acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy.

artículo científico publicado en 2006

FISH analysis with a YAC probe improves detection of LAZ3/BCL6 rearrangement in non-Hodgkin's lymphoma.

artículo científico publicado en 2000

Farnesyltransferase inhibitors and their potential role in therapy for myelodysplastic syndromes and acute myeloid leukaemia

artículo científico publicado en 2008

Favorable cytogenetic abnormalities in secondary leukemia

artículo científico publicado en 1989

Favorable evolution of lung interstitial disease in a patient with chronic myelomonocytic leukemia treated with azacitidine

artículo científico publicado en 2017

Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA)

artículo científico publicado en 2002

Favourable outcome in an APL patient with PLZF/RARalpha fusion gene: quantitative real-time RT-PCR confirms molecular response.

artículo científico publicado en 2006

Ferritin level at diagnosis is not correlated with poorer survival in non RBC transfusion dependent lower risk de novo MDS.

artículo científico publicado en 2011

Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia

artículo científico publicado en 2008

Fluorescence in situ hybridization improves the detection of monosomy 7 in myelodysplastic syndromes

scientific article published on 01 June 1994

Frequency of molecular elimination of Ph1 clone in chronic myelogenous leukemia (CML) with interferon alpha

scientific article published on 01 January 1996

Frequent antibody production against RARalpha in both APL mice and patients

artículo científico publicado en 2006

Functional G-CSF pathways in t(8;21) leukemic cells allow for differentiation induction and degradation of AML1-ETO.

artículo científico publicado en 2000

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

artículo científico publicado en 2016

Gamma-irradiation enhances transgene expression in leukemic cells

artículo científico publicado en 2003

Gastrointestinal Behcet’s-like disease with myelodysplastic neoplasms with trisomy 8: a French case series and literature review

article

Gene transfer of CD154 and IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia.

artículo científico publicado en 2002

Gene transfer of GM-CSF, CD80 and CD154 cDNA enhances survival in a murine model of acute leukemia with persistence of a minimal residual disease.

artículo científico publicado en 2000

Genetic analysis of therapy-related myeloid neoplasms occurring after intensive treatment for acute promyelocytic leukemia

artículo científico publicado en 2018

Germline DDX41 mutations define a significant entity within adult MDS/AML patients

scientific article published on 01 October 2019

Giant-cell arteritis associated with myelodysplastic syndrome: French multicenter case control study and literature review

artículo científico publicado en 2019

Glomerular injury in chronic myelomonocytic leukemia

artículo científico publicado en 1995

Glutathione S transferase theta 1 gene defects in myelodysplastic syndromes and their correlation with karyotype and exposure to potential carcinogens.

artículo científico publicado en 1997

Good predictive value of combined cytogenetic and molecular follow up in chronic myelogenous leukemia after non T-cell depleted allogeneic bone marrow transplantation: a report on 38 consecutive cases

artículo científico publicado en 1995

Granulocyte-macrophage colony-stimulating factor in association to timed-sequential chemotherapy with mitoxantrone, etoposide, and cytarabine for refractory acute myelogenous leukemia

scientific article published on 01 March 1993

Granulomonocytic progenitors are key target cells of azacytidine in higher risk myelodysplastic syndromes and acute myeloid leukemia

scholarly article by Ashfaq Ali et al published 26 February 2018 in Leukemia

Guadecitabine in myelodysplastic syndromes: promising but there is still progress to be made

artículo científico publicado en 2019

Guideline-based indicators for adult patients with myelodysplastic syndromes

scientific article published on 01 August 2020

Health, economic, and quality-of-life effects of erythropoietin and granulocyte colony-stimulating factor for the treatment of myelodysplastic syndromes: a randomized, controlled trial

artículo científico publicado en 2004

Health-related quality of life in lower-risk MDS patients compared with age- and sex-matched reference populations: a European LeukemiaNet study.

artículo científico publicado en 2018

Health-related quality of life outcomes of lenalidomide in transfusion-dependent patients with Low- or Intermediate-1-risk myelodysplastic syndromes with a chromosome 5q deletion: results from a randomized clinical trial

artículo científico publicado en 2012

Hematologic responses to deferasirox therapy in transfusion-dependent patients with myelodysplastic syndromes

artículo científico publicado en 2012

Hematopoietic growth factor expression and ATRA sensitivity in acute promyelocytic blast cells

artículo científico publicado en 1994

Hepatosplenic candidiasis: an overlooked cause of prolonged fever during recovery from an episode of neutropenia

artículo científico publicado en 1989

High body mass index is an independent predictor of differentiation syndrome in patients with acute promyelocytic leukemia

artículo científico publicado en 2009

High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21

artículo científico publicado en 2000

High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a

artículo científico publicado en 2006

High response rate and improved exercise capacity and quality of life with a new regimen of darbepoetin alfa with or without filgrastim in lower-risk myelodysplastic syndromes: a phase II study by the GFM.

artículo científico publicado en 2013

High-dose darbepoetin alpha in the treatment of anaemia of lower risk myelodysplastic syndrome results of a phase II study

artículo científico publicado en 2006

History of infections and vaccinations and risk of lymphoid neoplasms: does influenza immunization reduce the risk?

Hodgkin's disease disclosed by myelofibrosis of primary appearance. Apropos of 2 cases

artículo científico publicado el 1 de marzo de 1988

How we manage adults with myelodysplastic syndrome

artículo científico publicado en 2019

How we treat lower-risk myelodysplastic syndromes

artículo científico publicado en 2013

Hydroxyurea-induced apoptosis in an EBV-immortalized lymphoblastoid cell line

artículo científico publicado en 2004

Hypomethylating Agents and Other Novel Strategies in Myelodysplastic Syndromes

artículo científico publicado el 10 de enero de 2011

Hypomethylating Agents as Bridging Therapy before Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Chronic Myelomonocytic Leukemia?

scientific article published on 11 November 2015

Hypomethylating agents in relapsed and refractory AML: outcomes and their predictors in a large international patient cohort

artículo científico publicado en 2018

Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia

artículo científico publicado en 2011

Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion-Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study

artículo científico publicado en 2020

Immunoglobulin and T-cell receptor delta gene rearrangements are rarely found in myelodysplastic syndromes in chronic phase

scientific article published on 01 May 1994

Immunomodulating drugs in myelodysplastic syndromes

artículo científico publicado en 2011

Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias

artículo científico publicado en 2011

Impact of baseline cytogenetic findings and cytogenetic response on outcome of high-risk myelodysplastic syndromes and low blast count AML treated with azacitidine

artículo científico publicado en 2017

Impact of iron overload in myelodysplastic syndromes

artículo científico publicado en 2009

Impact of post-remission therapy in patients aged 65-70 years with de novo acute myeloid leukemia: a comparison of two concomitant randomized ALFA trials with overlapping age inclusion criteria

artículo científico publicado en 2011

Impact of red blood cell transfusion dose density on progression-free survival in patients with lower-risk myelodysplastic syndromes

scientific article published on 06 June 2019

Impact of somatic mutations on response to lenalidomide in lower-risk non-del(5q) myelodysplastic syndromes patients

scientific article published on 13 July 2020

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry

scientific article published on 05 July 2019

Implication of HTLV-I infection, strongyloidiasis, and P53 overexpression in the development, response to treatment, and evolution of non-Hodgkin's lymphomas in an endemic area (Martinique, French West Indies).

artículo científico publicado en 1999

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

artículo científico publicado en 2020

Improved outcome of acute promyelocytic leukemia with high WBC counts over the last 15 years: the European APL Group experience.

artículo científico publicado en 2009

In vitro all-trans retinoic acid sensitivity of acute promyelocytic leukemia blasts: a novel indicator of poor patient outcome

artículo científico publicado en 2001

In vitro treatment with retinoids or the topoisomerase inhibitor, VP-16, evidences different functional apoptotic pathways in acute promyelocytic leukemic cells

artículo científico publicado en 1995

In vivo thrombin and plasmin activities in patients with acute promyelocytic leukemia (APL): effect of all-trans retinoic acid (ATRA) therapy

artículo científico publicado en 1995

Inactivation of the p53 gene in leukemias and myelodysplastic syndrome (MDS) with 17p monosomy

scientific article published on 01 December 1994

Inactivation of the retinoblastoma gene appears to be very uncommon in myelodysplastic syndromes

scientific article published on 01 May 1994

Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission.

artículo científico publicado en 2010

Incidence of 17p deletions and TP53 mutation in myelodysplastic syndrome and acute myeloid leukemia with 5q deletion

scientific article published on 30 August 2012

Incidence of ATRX mutations in myelodysplastic syndromes, the value of microcytosis.

artículo científico publicado en 2015

Incidence, clinical features, and outcome of all trans-retinoic acid syndrome in 413 cases of newly diagnosed acute promyelocytic leukemia. The European APL Group.

artículo científico publicado en 1998

Increased frequency of hematopoietic malignancies in relatives of patients with lymphoid neoplasms: a French case-control study

artículo científico publicado en 2009

Increased gene transfer in acute myeloid leukemic cells by an adenovirus vector containing a modified fiber protein.

artículo científico publicado en 1999

Induction treatment of acute promyelocytic leukemia using all-trans retinoic acid. Controversies about dosage, advantages and side-effect management

scientific article published on 01 January 1994

Infectious complications in adult acute myeloid leukemia: analysis of the Acute Leukemia French Association-9802 prospective multicenter clinical trial

artículo científico publicado en 2012

Inflammatory arthritis in patients with myelodysplastic syndromes: a multicenter retrospective study and literature review of 68 cases

artículo científico publicado en 2014

Inflammatory disorders associated with trisomy 8‐myelodysplastic syndromes: French retrospective case‐control study

article

Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia

artículo científico publicado en 2006

Inhibitors of DNA methylation: beyond myelodysplastic syndromes

artículo científico publicado en 2005

Intensive chemotherapy for poor prognosis myelodysplasia (MDS) and secondary acute myeloid leukemia (sAML) following MDS of more than 6 months duration. A pilot study by the Leukemia Cooperative Group of the European Organisation for Research and Tr

scientific article published on 01 November 1995

Intensive sequential chemotherapy with mitoxantrone and continuous infusion etoposide and cytarabine for previously treated acute myelogenous leukemia

artículo científico publicado en 1991

Interferon alpha-2b therapy in refractory adult chronic thrombocytopenic purpura

artículo científico publicado en 1991

Interferon-alpha therapy in bcr-abl-negative myeloproliferative neoplasms.

scientific article published on 09 October 2008

International scoring system for evaluating prognosis in myelodysplastic syndromes

artículo científico publicado en 1997

Inv(16) may be one of the only 'favorable' factors in acute myeloid leukemia: a report on 19 cases with prolonged follow-up

scientific article published on 01 December 1994

Investigation of minimal residual disease in adult Ph1 positive acute lymphoblastic leukemia by a combination of cell sorting and fluorescence in situ hybridization: a preliminary study on 6 cases

artículo científico publicado en 2000

Iron overload and myelodysplastic syndromes

artículo científico publicado en 2001

Iron overload of hematological origin: validation of a screening procedure for cardiac overload by MRI in routine clinical practice.

artículo científico publicado en 2013

Is Cytarabine Useful in the Treatment of Acute Promyelocytic Leukemia? Results of a Randomized Trial From the European Acute Promyelocytic Leukemia Group

article by Lionel Adès et al published 20 December 2006 in Journal of Clinical Oncology

Is apoptosis a massive process in myelodysplastic syndromes?

scientific article published on 01 November 1996

Is cytarabine required in the treatment of acute promyelocytic leukemia?

artículo científico publicado en 2006

Is cytarabine required in the treatment of acute promyelocytic leukemia? Updated experience and review of the literature

artículo científico publicado en 2006

Is life expectancy of polycythemia vera patients clearly different from that of the general population?

artículo científico publicado en 2005

Is there a role for all-trans retinoic acid in combination with recombinant erythropoetin in myelodysplastic syndromes? A report on 59 cases

artículo científico publicado en 2009

Is there still a role for low-dose cytosine arabinoside in de novo acute myeloid leukemia in the elderly? A report on 77 cases

artículo científico publicado en 1993

Is translocation (8;21) a "favorable" cytogenetic rearrangement in acute myeloid leukemia?

artículo científico publicado en 1990

Isolated pericardial and mediastinal relapse following allogeneic bone marrow transplantation for acute lymphoblastic leukemia

scientific article published on 01 May 1991

Late first relapses in APL treated with all-trans-retinoic acid- and anthracycline- based chemotherapy: the European APL group experience (APL 91 and APL 93 trials)

artículo científico publicado en 2006

Lenalidomide as a disease-modifying agent in patients with del(5q) myelodysplastic syndromes: linking mechanism of action to clinical outcomes

artículo científico publicado en 2014

Lenalidomide combined with intensive chemotherapy in acute myeloid leukemia and higher-risk myelodysplastic syndrome with 5q deletion. Results of a phase II study by the Groupe Francophone Des Myélodysplasies

artículo científico publicado en 2016

Lenalidomide does not increase AML progression risk in RBC transfusion-dependent patients with Low- or Intermediate-1-risk MDS with del(5q): a comparative analysis.

artículo científico publicado en 2012

Lenalidomide in lower-risk myelodysplastic syndromes with karyotypes other than deletion 5q and refractory to erythropoiesis-stimulating agents

artículo científico publicado en 2011

Lenalidomide with or without erythropoietin in transfusion-dependent erythropoiesis-stimulating agent-refractory lower-risk MDS without 5q deletion.

artículo científico publicado en 2015

Lenalidomide-mediated erythroid improvement in non-del(5q) myelodysplastic syndromes is associated with bone marrow immuno-remodeling

artículo científico publicado en 2017

Lithium chloride antileukemic activity in acute promyelocytic leukemia is GSK-3 and MEK/ERK dependent.

artículo científico publicado en 2015

Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes

artículo científico publicado en 2012

Long-term follow-up confirms the benefit of all-trans retinoic acid in acute promyelocytic leukemia. European APL group

artículo científico publicado en 2000

Long-term follow-up for up to 5 years on the risk of leukaemic progression in thrombocytopenic patients with lower-risk myelodysplastic syndromes treated with romiplostim or placebo in a randomised double-blind trial

artículo científico publicado en 2018

Long-term follow-up of European APL 2000 trial, evaluating the role of cytarabine combined with ATRA and Daunorubicin in the treatment of nonelderly APL patients

artículo científico publicado en 2013

Long-term follow-up of autologous stem cell transplantation after intensive chemotherapy in patients with myelodysplastic syndrome or secondary acute myeloid leukemia

artículo científico publicado en 2006

Long-term follow-up of chronic autoimmune thrombocytopenic purpura refractory to splenectomy: a prospective analysis

artículo científico publicado en 2003

Long-term incidence of hematological evolution in three French prospective studies of hydroxyurea and pipobroman in polycythemia vera and essential thrombocythemia.

artículo científico publicado en 2006

Long-term outcome of anemic lower-risk myelodysplastic syndromes without 5q deletion refractory to or relapsing after erythropoiesis-stimulating agents.

artículo científico publicado en 2013

Long-term outcome of higher-risk MDS patients treated with azacitidine: an update of the GFM compassionate program cohort

artículo científico publicado en 2012

Long-term survivors in myelodysplastic syndromes: a report on 63 cases and comparison with short and intermediate survivors

artículo científico publicado en 1993

Low dose IL-2 in patients with steroid-dependent dysimmune manifestations associated with myelodysplastic syndromes: a three-case report

artículo científico publicado en 2020

Low incidence of specific anti-platelet antibodies detected by the MAIPA assay in the serum of thrombocytopenic MDS patients and lack of correlation between platelet autoantibodies, platelet lifespan and response to danazol therapy

artículo científico publicado en 1996

Low-dose cytosine arabinoside (LD-AraC) vs LD-AraC plus granulocyte/macrophage colony stimulating factor vs LD-AraC plus Interleukin-3 for myelodysplastic syndrome patients with a high risk of developing acute leukemia: final results of a randomized

artículo científico publicado en 2005

Low-dose cytosine arabinoside in adult chronic myelomonocytic leukemia

artículo científico publicado en 1987

Luspatercept for the treatment of anemia in myelodysplastic syndromes and primary myelofibrosis

scientific article published on 02 January 2019

Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes

scientific article published on 01 January 2020

M0 AML, clinical and biologic features of the disease, including AML1 gene mutations: a report of 59 cases by the Groupe Français d'Hématologie Cellulaire (GFHC) and the Groupe Français de Cytogénétique Hématologique (GFCH)

artículo científico publicado en 2002

MDM2 gene amplification in human breast cancer

scientific article published on 01 January 1994

MIRROS: a randomized, placebo-controlled, Phase III trial of cytarabine ± idasanutlin in relapsed or refractory acute myeloid leukemia

artículo científico publicado en 2020

Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine*.

artículo científico publicado en 2010

Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet

artículo científico publicado en 2008

Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet

scholarly article by Miguel A Sanz et al published 11 April 2019 in Blood

Management of myelodysplastic syndromes

artículo científico publicado en 2015

Meeting report: myelodysplastic syndromes at ASH 2007.

artículo científico publicado en 2008

Meeting report: the 11th International Conference on Differentiation Therapy and Innovative Therapeutics in Oncology.

artículo científico publicado en 2007

Mesenchymal cells generated from patients with myelodysplastic syndromes are devoid of chromosomal clonal markers and support short- and long-term hematopoiesis in vitro.

artículo científico publicado en 2005

Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression

scientific article published on 01 April 1998

Minimizing risk of hypomethylating agent failure in patients with higher-risk MDS and practical management recommendations

artículo científico publicado en 2014

Modulation of IL-8, IL-1 beta, and G-CSF secretion by all-trans retinoic acid in acute promyelocytic leukemia

artículo científico publicado el 1 de octubre de 1994

Molecular characterization of the idiopathic hypereosinophilic syndrome (HES) in 35 French patients with normal conventional cytogenetics.

artículo científico publicado en 2005

Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.

artículo científico publicado en 2011

Molecular remission as a therapeutic objective in acute promyelocytic leukemia

artículo científico publicado en 2018

Multicenter validation of the flow measurement of classical monocyte fraction for chronic myelomonocytic leukemia diagnosis

scholarly article by Sihem Tarfi et al published 14 November 2018 in Blood Cancer Journal

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

artículo científico publicado en 2016

Mutations in exon 12 of JAK2 are mainly found in JAK2 V617F-negative polycythaemia vera patients.

artículo científico publicado en 2008

Mutations in the p53 gene in myelodysplastic syndromes

artículo científico publicado en 1991

Mutations of PTPN11 are rare in adult myeloid malignancies

artículo científico publicado en 2005

Mutations of the P53 gene in acute myeloid leukaemia

artículo científico publicado en 1992

Mutations of the p53 gene in B-cell chronic lymphocytic leukemia: a report on 39 cases with cytogenetic analysis

artículo científico publicado el 1 de abril de 1992

Mutations of the p53 gene in B-cell lymphoblastic acute leukemia: a report on 60 cases

artículo científico publicado en 1992

Myelodysplastic Syndrome and Giant Cell Arteritis: A Nonfortuitous Association that Geriatricians Should Know About.

artículo científico publicado en 2017

Myelodysplastic Syndromes (MDS) and autoimmune disorders (AD): cause or consequence?

artículo científico

Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

Myelodysplastic syndrome (MDS) with isolated trisomy 8: a type of MDS frequently associated with myeloproliferative features? A report by the Groupe Francophone des Myélodysplasies

scientific article published on 13 July 2018

Myelodysplastic syndrome after acute promyelocytic leukemia: the European APL group experience

artículo científico publicado en 2003

Myelodysplastic syndromes

artículo científico publicado en 2014

Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoïesis and a high incidence of P53 mutations

artículo científico publicado en 1995

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

artículo científico publicado en 2014

Myelodysplastic syndromes during pregnancy

artículo científico publicado en 1991

Myelodysplastic syndromes with single neutropenia or thrombocytopenia are rarely refractory cytopenias with unilineage dysplasia by World Health Organization 2008 criteria and have favourable prognosis

artículo científico publicado en 2016

Myelodysplastic syndromes: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

artículo científico publicado en 2014

Myelodysplastic syndromes: From pathogenesis and prognosis to treatment

artículo científico publicado en 2004

Myelodysplastic syndromes: state of the art pathology, diagnosis and management

artículo científico publicado en 2013

NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome

artículo científico publicado en 2005

NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia

artículo científico publicado en 2007

Neurological disorders in essential thrombocythemia

artículo científico publicado en 2011

New mechanisms of AML1 gene alteration in hematological malignancies

artículo científico publicado en 2003

New role for granulocyte colony-stimulating factor-induced extracellular signal-regulated kinase 1/2 in histone modification and retinoic acid receptor α recruitment to gene promoters: relevance to acute promyelocytic leukemia cell differentiation.

artículo científico publicado en 2011

Non-allogeneic immunotherapy in acute myeloid leukaemia

artículo científico publicado en 2019

Non-del(5q) myelodysplastic syndromes-associated loci detected by SNP-array genome-wide association meta-analysis

scientific article published on 01 November 2019

Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma

artículo científico publicado en 2000

Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective

artículo científico publicado en 2020

Occupation and lymphoid malignancies: results from a French case-control study

artículo científico publicado en 2007

Occupational and environmental risk factors of the myelodysplastic syndromes in the North of France.

artículo científico publicado en 2001

Occupational exposure to organic solvents and lymphoid neoplasms in men: results of a French case-control study

artículo científico publicado en 2010

Occupational exposure to pesticides and lymphoid neoplasms among men: results of a French case-control study

artículo científico publicado en 2008

Occurrence of myelodysplastic syndrome in 2 patients with reticular dysgenesis

artículo científico publicado en 2011

Optimal sequencing of treatments for patients with myelodysplastic syndromes

artículo científico publicado en 2009

Optimizing hypomethylating agents in myelodysplastic syndromes

artículo científico

Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents

artículo científico publicado en 2017

Outcome of acute myeloid leukaemia following myelodysplastic syndrome after azacitidine treatment failure.

artículo científico publicado en 2012

Outcome of acute promyelocytic leukemia (APL) in children and adolescents: an analysis in two consecutive trials of the European APL Group.

artículo científico publicado en 2012

Outcome of acute promyelocytic leukemia treated with all trans retinoic acid and chemotherapy in elderly patients: the European group experience.

artículo científico publicado en 2005

Outcome of childhood acute promyelocytic leukemia with all-trans-retinoic acid and chemotherapy.

artículo científico publicado en 2004

Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure

artículo científico publicado en 2011

Outcome of lower-risk myelodysplastic syndrome with ring sideroblasts (MDS-RS) after failure of erythropoiesis- stimulating agents

artículo científico publicado en 2020

Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide-an International Collaborative Study

artículo científico publicado en 2020

Outcome of older patients with acute myeloid leukemia in first relapse

artículo científico publicado en 2013

Outcome of patients less than 55 years of age with high-risk acute leukemia who did not have an human leukocyte antigen-identical related donor: a long-term study of 97 consecutive patients

scientific article published on 01 June 2005

Outcome of patients treated for myelodysplastic syndromes with 5q deletion after failure of lenalidomide therapy.

artículo científico publicado en 2017

Outcome of patients treated for myelodysplastic syndromes without deletion 5q after failure of lenalidomide therapy

artículo científico publicado en 2017

Outcome of patients with high risk Myelodysplastic Syndrome (MDS) and advanced Chronic Myelomonocytic Leukemia (CMML) treated with decitabine after azacitidine failure.

artículo científico publicado en 2015

Outcome of patients with low-risk myelodysplasia after azacitidine treatment failure

artículo científico publicado en 2012

Outcome of treatment after first relapse in younger adults with acute myeloid leukemia initially treated by the ALFA-9802 trial

artículo científico publicado en 2012

Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia--results of the prospective multicenter LALA-94 trial

artículo científico publicado en 2002

Outcome of treatment in adults with acute lymphoblastic leukemia: analysis of the LALA-94 trial

artículo científico publicado en 2004

Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study

artículo científico publicado en 2014

Over-expression of the MDM2 gene is found in some cases of haematological malignancies.

artículo científico publicado en 1994

P53 gene mutations in acute myeloid leukemia with 17p monosomy.

artículo científico publicado en 1991

Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera

article

Performance of the Medical Research Council (MRC) and the Leukemia Research Foundation (LRF) score in predicting survival benefit with hypomethylating agent use in patients with relapsed or refractory acute myeloid leukemia

artículo científico publicado en 2018

Persistence of AML1/ETO fusion mRNA in t(8;21) acute myeloid leukemia (AML) in prolonged remission: is there a consensus?

scientific article published on 01 January 1996

Personalized medicine in myelodysplastic syndromes: wishful thinking or already clinical reality?

artículo científico publicado en 2015

Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome

artículo científico publicado en 2010

Phase I study of cinchonine, a multidrug resistance reversing agent, combined with the CHVP regimen in relapsed and refractory lymphoproliferative syndromes.

artículo científico publicado en 2000

Phase II trial of CPT-11 in myelodysplastic syndromes with excess of marrow blasts

artículo científico publicado en 2003

Philadelphia negative, BCR-ABL positive adult acute lymphoblastic leukemia (ALL) in 2 of 39 patients with combined cytogenetic and molecular analysis

artículo científico publicado en 1993

Polymorphism of the proto-oncogene ETS-1 in hematological malignancies

artículo científico publicado en 1990

Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial

artículo científico publicado en 2007

Practical recommendations on the use of lenalidomide in the management of myelodysplastic syndromes

artículo científico publicado en 2008

Practical use of azacitidine in higher-risk myelodysplastic syndromes: an expert panel opinion

artículo científico publicado en 2010

Preclinical modeling of myelodysplastic syndromes

artículo científico publicado en 2017

Predicting outcome of patients with myelodysplastic syndromes after failure of azacitidine: validation of the North American MDS consortium scoring system

artículo científico publicado en 2016

Predicting the outcome of patients with higher-risk myelodysplastic syndrome treated with hypomethylating agents

artículo científico publicado en 2012

Predictive factors of response and survival among chronic myelomonocytic leukemia patients treated with azacitidine

artículo científico publicado en 2013

Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF: the GFM experience

artículo científico publicado en 2007

Predisposition to therapy-related acute leukemia with balanced chromosomal translocations does not result from a major constitutive defect in DNA double-strand break end joining

artículo científico publicado en 2006

Present results of the treatment of myelodysplastic syndromes with low-dose cytosine arabinoside. Preliminary results of a cooperative protocol (38 patients) and review of the literature

artículo científico publicado en 1987

Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype

artículo científico publicado en 2005

Primary breast lymphoma: a report of 20 cases

artículo científico publicado en 2001

Primary central nervous system lymphoma in immunocompetent adults: poor results mainly associated with high treatment related toxicities.

artículo científico publicado en 2002

Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes

artículo científico publicado en 2017

Problematic WHO reclassification of myelodysplastic syndromes. Members of the International MDS Study Group.

artículo científico publicado en 2000

Prognosis and treatment of lymphoblastic lymphoma in adults: a report on 80 patients

scientific article published on 01 July 1992

Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup

artículo científico publicado en 2003

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents.

artículo científico publicado en 2018

Prognostic classification of myelofibrosis with myeloid metaplasia

scientific article published on 01 September 1989

Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.

artículo científico publicado en 2010

Prognostic factors in Waldenström's macroglobulinemia: a report of 167 cases

artículo científico publicado en 1993

Prognostic factors in adult chronic myelomonocytic leukemia: an analysis of 107 cases

artículo científico publicado en 1988

Prognostic factors in adult de novo myelodysplastic syndromes treated by intensive chemotherapy.

artículo científico publicado en 1991

Prognostic factors in myelodysplastic syndromes: critical analysis of the impact of age and gender and failure to identify a very-low-risk group using standard mortality ratio techniques

artículo científico publicado en 1996

Prognostic factors of acute non lymphoblastic leukemia in children and adults. Results from two multicentric trials (705 patients)

Prognostic impact of JAK2V617F mutation in myelodysplatic syndromes: A matched case control study

artículo científico publicado en 2013

Prognostic impact of a suboptimal number of analyzed metaphases in normal karyotype lower-risk MDS.

artículo científico publicado en 2018

Prognostic implication of FLT3 and Ras gene mutations in patients with acute promyelocytic leukemia (APL): a retrospective study from the European APL Group

article

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

artículo científico publicado en 2013

Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association

artículo científico publicado en 2012

Prognostic significance of FLT3 internal tandem repeat in patients with de novo acute myeloid leukemia treated with reinforced courses of chemotherapy

scientific article published on 01 September 2002

Prognostic significance of monosomal karyotype in higher risk myelodysplastic syndrome treated with azacitidine

artículo científico publicado en 2011

Prognostic significance of p16INK4a immunocytochemistry in adult ALL with standard risk karyotype

artículo científico publicado en 2001

Prognostic significance of the balanced t(1;19) and unbalanced der(19)t(1;19) translocations in acute lymphoblastic leukemia

artículo científico publicado en 1992

Prognostic value of GST-pi expression in diffuse large B-cell lymphomas

artículo científico publicado en 2003

Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine

artículo científico publicado en 2014

Prognostic value of c-mpl expression in myelodysplastic syndromes

artículo científico publicado en 1995

Prognostic value of dysmyelopoietic features in de novo acute myeloid leukaemia: a report on 132 patients

scientific article published on 01 January 1990

Prognostic value of monocyte subset distribution in chronic myelomonocytic leukemia: results of a multicenter study

artículo científico publicado en 2020

Prognostic value of real-time quantitative PCR (RQ-PCR) in AML with t(8;21).

artículo científico publicado en 2005

Prolonged follow-up confirms that all-trans retinoic acid followed by chemotherapy reduces the risk of relapse in newly diagnosed acute promyelocytic leukemia. The French APL Group

artículo científico publicado en 1994

Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: azacitidine compared with low dose ara-C.

artículo científico publicado en 2010

Promyelocytic blast crisis of Philadelphia-positive thrombocythemia with translocations (9;22) and (15;17).

artículo científico publicado en 1987

Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System

artículo científico publicado en 2008

Proposals for revised IWG 2018 hematological response criteria in patients with MDS included in clinical trials

artículo científico publicado en 2018

Pulsed high-dose dexamethasone in refractory chronic idiopathic thrombocytopenic purpura: a report on 10 cases

artículo científico publicado en 1995

Question prompt list responds to information needs of myelodysplastic syndromes patients and caregivers

artículo científico publicado en 2015

Quinine improves the results of intensive chemotherapy in myelodysplastic syndromes expressing P glycoprotein: results of a randomized study.

artículo científico publicado en 1998

RNA for reverse PCR analysis can be obtained from bone marrow cells prepared for cytogenetic analysis and stored at -20 degrees C for several years

scientific article published on 01 August 1995

Randomized Phase III Study of Lenalidomide Versus Placebo in RBC Transfusion-Dependent Patients With Lower-Risk Non-del(5q) Myelodysplastic Syndromes and Ineligible for or Refractory to Erythropoiesis-Stimulating Agents

artículo científico publicado en 2016

Randomized comparison of double induction and timed-sequential induction to a "3 + 7" induction in adults with AML: long-term analysis of the Acute Leukemia French Association (ALFA) 9000 study

article

Randomized study of intensified anthracycline doses for induction and recombinant interleukin-2 for maintenance in patients with acute myeloid leukemia age 50 to 70 years: results of the ALFA-9801 study

artículo científico publicado en 2010

Rare occurrence of P53 gene mutations in multiple myeloma

artículo científico publicado en 1992

Rare occurrence of mutations of the FLR exon of the neurofibromatosis 1 (NF1) gene in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)

artículo científico publicado en 1993

Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group

artículo científico publicado en 2012

Re-evaluation of the role of azathioprine in the treatment of adult chronic idiopathic thrombocytopenic purpura: a report on 53 cases

artículo científico publicado en 1990

Real life experience with frontline azacitidine in a large series of older adults with acute myeloid leukemia stratified by MRC/LRF score: results from the expanded international E-ALMA series (E-ALMA+).

artículo científico publicado en 2017

Rearrangement and expression of the p53 gene in myelodysplastic syndrome and acute myeloid leukemia

artículo científico publicado en 1990

Reassessment of an apparent t(12;17)(p11;p11) as an unbalanced t(17;21)(p11;q11) in a case of B-cell chronic lymphocytic leukemia by fluorescence in situ hybridization

artículo científico publicado en 1994

Recent advances in the treatment of lower-risk non-del(5q) myelodysplastic syndromes (MDS)

artículo científico publicado en 2016

Recent frustration and innovation in myelodysplastic syndrome

artículo científico publicado en 2016

Recombinant human erythropoietin at high dose is effective for the treatment of the anemia of myelodysplastic syndromes

scientific article published on 01 January 1991

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

artículo científico publicado en 2017

Recurrent in-frame insertion in C/EBPα TAD2 region is a polymorphism without prognostic value in AML

artículo científico publicado en 2007

Reducing mortality in newly diagnosed standard-risk acute promyelocytic leukemia in elderly patients treated with arsenic trioxide requires major reduction of chemotherapy: a report by the French Belgian Swiss APL group (APL 2006 trial)

article

Reevaluation of the prognostic factors for splenectomy in chronic idiopathic thrombocytopenic purpura (ITP): a report on 181 cases.

artículo científico publicado en 1989

Refractory anaemia according to the FAB classification: A report on 69 cases

artículo científico publicado el 1 de abril de 1988

Refractory thrombocytopenia and neutropenia: a diagnostic challenge

artículo científico publicado en 2015

Relapsing polychondritis and chronic myelomonocytic leukemia

artículo científico publicado en 2009

Relationship between p53 gene mutations and multidrug resistance (mdr1) gene expression in myelodysplastic syndromes

scientific article published on 01 November 1993

Relationship of different platelet response criteria and patient outcomes in a romiplostim myelodysplastic syndromes trial

artículo científico publicado en 2014

Resistance to all-trans retinoic acid (ATRA) therapy in relapsing acute promyelocytic leukemia: study of in vitro ATRA sensitivity and cellular retinoic acid binding protein levels in leukemic cells

artículo científico publicado en 1993

Response assessments in low-risk and high-risk myelodysplastic syndromes (MDS).

artículo científico publicado en 2005

Results of a randomized, double-blind study of romiplostim versus placebo in patients with low/intermediate-1-risk myelodysplastic syndrome and thrombocytopenia

artículo científico publicado en 2014

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells

artículo científico publicado en 2015

Retinoid differentiation therapy in promyelocytic leukemia

artículo científico publicado en 1996

Review of azacitidine trials in Intermediate-2-and High-risk myelodysplastic syndromes

artículo científico publicado en 2009

Revised international prognostic scoring system for myelodysplastic syndromes

artículo científico publicado en 2012

Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial

artículo científico publicado en 2016

Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura: results of a prospective multicenter phase 2 study

artículo científico publicado en 2008

Role of early splenectomy in malignant lymphomas with prominent splenic involvement (primary lymphomas of the spleen). A study of 59 cases

artículo científico publicado en 1993

Role of multiplex FISH in identifying chromosome involvement in myelodysplastic syndromes and acute myeloid leukemias with complex karyotypes: a report on 28 cases

artículo científico publicado en 2005

Role of reduced-intensity conditioning allogeneic hematopoietic stem-cell transplantation in older patients with de novo myelodysplastic syndromes: an international collaborative decision analysis

artículo científico publicado en 2013

Role of splenectomy in the treatment of myelodysplastic syndromes with peripheral thrombocytopenia: a report on six cases

artículo científico publicado en 2001

Romiplostim monotherapy in thrombocytopenic patients with myelodysplastic syndromes: long-term safety and efficacy

artículo científico publicado en 2017

Routine diagnostic procedures of myelodysplastic syndromes: value of a structural blood cell parameter (NEUT-X) determined by the Sysmex XE-2100™.

artículo científico publicado en 2010

SF3B1-mutant myelodysplastic syndrome as a distinct disease subtype - A Proposal of the International Working Group for the Prognosis of Myelodysplastic Syndromes (IWG-PM)

artículo científico publicado en 2020

Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia

artículo científico publicado en 2009

Safety profile of lenalidomide in patients with lower-risk myelodysplastic syndromes without del(5q): results of a phase 3 trial

artículo científico publicado en 2018

Scoring system for the prediction of successful peripheral blood stem cell (PBSC) collection in non-Hodgkin's lymphoma (NHL): application in clinical practice

scientific article published on 01 March 2000

Secondary acute lymphoblastic leukemia with t (4;11): report on two cases and review of the literature

artículo científico publicado el 1 de septiembre de 1992

Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment.

artículo científico publicado en 2002

Should all CMV infections after bone marrow transplantation be treated?

artículo científico publicado el 1 de enero de 1991

Simultaneous occurrence of grey platelet syndrome and idiopathic pulmonary fibrosis: a role for abnormal megakaryocytes in the pathogenesis of pulmonary fibrosis?

artículo científico publicado en 1990

Single agent talacotuzumab demonstrates limited efficacy but considerable toxicity in elderly high-risk MDS or AML patients failing hypomethylating agents

scientific article published on 03 December 2019

Slow infusions of vinblastine in the treatment of adult idiopathic thrombocytopenic purpura: a report on 43 cases

artículo científico publicado en 1990

Slow relapse in acute myeloid leukemia with inv(16) or t(16;16).

artículo científico publicado en 2009

Somatic mutations and epigenetic abnormalities in myelodysplastic syndromes.

artículo científico publicado en 2013

Sotatercept with long-term extension for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes: a phase 2, dose-ranging trial

artículo científico publicado en 2018

Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

scientific article published on 18 June 2020

Splenic irradiation for chronic autoimmune thrombocytopenic purpura in patients with contra‐indications to splenectomy

artículo científico publicado el 1 de septiembre de 1995

Spontaneous conception after autologous hematopoietic stem cell transplantation: a case report

artículo científico publicado en 2012

Strongyloidiasis in man 75 years after initial exposure

artículo científico publicado en 2011

Subcutaneous or intravenous administration of romiplostim in thrombocytopenic patients with lower risk myelodysplastic syndromes

artículo científico publicado el 13 de octubre de 2010

Successful autologous bone marrow transplantation in second remission of malignant histiocytosis

artículo científico publicado el 1 de junio de 1990

Successful treatment of juvenile rheumatoid arthritis associated haemophagocytic syndrome by cyclosporin A with transient exacerbation by conventional-dose G-CSF

artículo científico publicado en 1997

Successful xenografts of AML3 samples in immunodeficient NOD/shi-SCID IL2Rγ−/− mice

artículo científico publicado en 2012

Superior long-term outcome with idarubicin compared with high-dose daunorubicin in patients with acute myeloid leukemia age 50 years and older

artículo científico publicado en 2012

Superiority of an arsenic trioxide-based regimen over a historic control combining all-trans retinoic acid plus intensive chemotherapy in the treatment of relapsed acute promyelocytic leukemia

artículo científico publicado en 2006

Supportive care including growth factors in myelodysplastic syndromes.

artículo científico publicado en 2004

Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome

artículo científico publicado en 2009

Survival, prognostic factors and rates of leukemic transformation in 381 untreated patients with MDS and del(5q): a multicenter study.

artículo científico publicado en 2012

Synchronous FIP1L1-PDGFRA-positive chronic eosinophilic leukemia and T-cell lymphoblastic lymphoma: a bilineal clonal malignancy

artículo científico publicado en 2007

Synergistic effects of PRIMA-1Met (APR-246) and Azacitidine in TP53-mutated myelodysplastic syndromes and acute myeloid leukemia

scientific article published on 05 September 2019

Systemic and autoimmune manifestations in myelodysplastic syndromes

artículo científico publicado el 20 de septiembre de 2010

Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective study

artículo científico publicado en 2015

Systemic injection of GM-CSF increases survival in a murine model of acute leukemia

artículo científico publicado en 2002

T-cell acute lymphoblastic leukemia occurring in the course of B cell chronic lymphocytic leukemia: a case report.

artículo científico publicado en 1995

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

scientific article published on October 2009

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

artículo científico publicado en 2009

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

scientific article published on 11 January 2019

Targeting NF-kappaB in hematologic malignancies

artículo científico publicado en 2006

The 5q- syndrome

artículo científico publicado en 2010

The Effect of Lenalidomide on Health-Related Quality of Life in Patients With Lower-Risk Non-del(5q) Myelodysplastic Syndromes: Results From the MDS-005 Study

artículo científico publicado en 2017

The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow

artículo científico publicado en 2006

The clinical safety of lenalidomide in multiple myeloma and myelodysplastic syndromes

artículo científico publicado en 2011

The clinical significance of mutations of the P53 tumour suppressor gene in haematological malignancies

artículo científico publicado en 1997

The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants

artículo científico publicado en 2020

The effects of continued azacitidine treatment cycles on response in higher risk patients with myelodysplastic syndromes: an update.

artículo científico publicado en 2008

The first international meeting on V617F JAK2 mutation and its relevance in Philadelphia-negative myeloproliferative disorders.

artículo científico publicado en 2006

The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases

artículo científico publicado en 2008

The retinoblastoma gene (RB-1) status in multiple myeloma: a report on 35 cases.

artículo científico publicado en 1995

The retinoic acid receptor alpha gene is rearranged in retinoic acid-sensitive promyelocytic leukemias

artículo científico publicado en 1990

The revised IPSS is a powerful tool to evaluate the outcome of MDS patients treated with azacitidine: the GFM experience

artículo científico publicado en 2012

The role of danazol in the treatment of refractory idiopathic thrombocytopenic purpura. A report of 22 cases

artículo científico publicado en 1990

The role of intensive chemotherapy in myelodysplastic syndromes.

artículo científico publicado en 1992

The role of lenalidomide in the management of myelodysplasia with del 5q.

artículo científico publicado en 2008

The treatment of adult idiopathic thrombocytopenic purpura. Infusion of vinblastine in ITP.

artículo científico publicado en 1987

The use of immunosuppressive therapy in MDS: clinical outcomes and their predictors in a large international patient cohort

artículo científico publicado en 2018

Therapy-related acute promyelocytic leukaemia

scientific article published on 01 June 1994

Therapy-related acute promyelocytic leukemia.

artículo científico publicado en 2003

Thrombotic microangiopathy: a new dose-limiting toxicity of high-dose sequential chemotherapy

artículo científico publicado en 2001

Time-dependent changes in mortality and transformation risk in MDS.

artículo científico publicado en 2016

Time-dependent prognostic scoring system for myelodysplastic syndromes has significant limitations that may influence its reproducibility and practical application

artículo científico publicado en 2008

Timed sequential chemotherapy for advanced acute myeloid leukemia

artículo científico publicado en 1996

Timed sequential chemotherapy for previously treated patients with acute myeloid leukemia: long-term follow-up of the etoposide, mitoxantrone, and cytarabine-86 trial

artículo científico publicado en 1995

Total peroxidase deficiency in eosinophils: a report on twin sisters, one with a refractory anaemia.

artículo científico publicado en 1987

Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia

artículo científico publicado en 2011

Transduction of bone marrow cells by the AdZ.F(pK7) modified adenovirus demonstrates preferential gene transfer in myeloma cells.

artículo científico publicado en 1999

Transfer of p16inka/CDKN2 gene in leukaemic cell lines inhibits cell proliferation

artículo científico publicado en 1996

Translocation (1;7) in a case of secondary chronic myelomonocytic leukemia

scientific article published on 01 February 1987

Translocation t(10;17)(p13;q12) in two cases of acute nonlymphocytic leukemia with phagocytic activity of blasts. A new cytogenetic entity?

scientific article published on 01 May 1989

Translocation t(1;19)(q23;p13) in acute lymphoblastic leukemia. A report on six new cases and an unusual t(17;19)(q11;q13), with special reference to prognostic factors

scientific article published on 01 January 1989

Translocation t(9;11)(p21;q23) with acute myelomonocytic leukemia after chemotherapy for osteosarcoma: good response to antileukemic drugs

artículo científico publicado en 1987

Translocations (5;17) and (7;17) in patients with de novo or therapy-related myelodysplastic syndromes or acute nonlymphocytic leukemia. A possible association with acquired pseudo-Pelger-Huët anomaly and small vacuolated granulocytes

artículo científico

Treatment by Lenalidomide in lower risk myelodysplastic syndrome with 5q deletion--the GFM experience

artículo científico publicado en 2011

Treatment of Acute Promyelocytic Leukemia with AIDA Based Regimen. Update of a Tunisian Single Center Study

artículo científico publicado en 2011

Treatment of Acute Promyelocytic Leukemia: A Report of 70 Cases

artículo científico publicado en 1991

Treatment of acute promyelocytic leukaemia

scientific article published on 01 March 1996

Treatment of acute promyelocytic leukaemia.

artículo científico publicado en 2001

Treatment of acute promyelocytic leukemia with all-trans retinoic acid

artículo científico publicado en 1991

Treatment of acute promyelocytic leukemia with high white cell blood counts

artículo científico publicado en 2011

Treatment of advanced myelodysplastic syndrome with demethylating agents: azacitidine

artículo científico publicado en 2012

Treatment of first relapse in acute promyelocytic leukaemia with all-trans retinoic acid.

artículo científico publicado en 1990

Treatment of myelodysplastic syndrome with thrombomimetic drugs

artículo científico publicado en 2014

Treatment of myelodysplastic syndromes with 5q deletion before the lenalidomide era; the GFM experience with EPO and thalidomide

artículo científico publicado en 2008

Treatment of myelodysplastic syndromes with excess of blasts by bevacizumab is well tolerated and is associated with a decrease of VEGF plasma level

artículo científico publicado en 2011

Treatment of newly diagnosed acute promyelocytic leukemia (APL) by a combination of all-trans retinoic acid (ATRA) and chemotherapy. French APL Group

artículo científico publicado en 1994

Treatment of newly diagnosed acute promyelocytic leukemia (APL): a comparison of French-Belgian-Swiss and PETHEMA results

artículo científico publicado en 2007

Treatment of older adults with acute promyelocytic leukaemia

artículo científico publicado en 2003

Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM).

artículo científico publicado en 2010

Treatment of severe aplastic anemia with antilymphocyte globulin and androgens: a report on 33 patients

artículo científico publicado en 1991

Treatment of the 5q- syndrome

artículo científico publicado en 2006

Treatment with lenalidomide does not appear to increase the risk of progression in lower risk myelodysplastic syndromes with 5q deletion. A comparative analysis by the Groupe Francophone des Myelodysplasies

artículo científico publicado en 2011

Treatment with very low-dose GM-CSF in myelodysplastic syndromes with neutropenia. A report on 28 cases

scientific article published on 01 September 1994

Tretinoin with chemotherapy in newly diagnosed acute promyelocytic leukaemia. European APL Group

artículo científico publicado en 1994

Trisomy 6 as the sole chromosome abnormality in myeloid disorders

artículo científico publicado en 1994

Tyrosine kinase inhibitors for the treatment of acute myeloid leukemia: delineation of anti-leukemic mechanisms of action

artículo científico publicado en 2011

UV radiation exposure, skin type and lymphoid malignancies: results of a French case-control study.

artículo científico publicado en 2007

Unlike AML1, CBFbeta gene is not deregulated by point mutations in acute myeloid leukemia and in myelodysplastic syndromes

scientific article published on 01 May 2002

Unusual clonal evolution involving 5q in a case of myelodysplastic syndrome with deletion 5q 31 treated with lenalidomide

artículo científico publicado en 2008

Unusual recurrence of chronic myelogenous leukemia following bone marrow transplantation

artículo científico publicado en 1991

Upfront allogeneic stem cell transplantation after reduced-intensity/nonmyeloablative conditioning for patients with myelodysplastic syndrome: a study by the Société Française de Greffe de Moelle et de Thérapie Cellulaire.

artículo científico publicado en 2014

Usefulness of electron microscopy in the diagnosis of congenital dyserythropoietic anemia type I: report of a case

artículo científico publicado en 1991

V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis

artículo científico publicado en 2005

VIM3-ARA C: an effective salvage regimen in refractory or recurrent aggressive non Hodgkin's lymphoma. A report on 18 cases

artículo científico publicado en 1991

Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R). A study of the International Working Group for Prognosis in Myelo

artículo científico publicado en 2015

Validation of a post-hypomethylating agent failure prognostic model in myelodysplastic syndromes patients treated in a randomized controlled phase III trial of rigosertib vs. best supportive care

artículo científico publicado en 2017

Validation of response assessment according to international consortium for MDS/MPN criteria in chronic myelomonocytic leukemia treated with hypomethylating agents.

artículo científico publicado en 2017

Validation of the IPSS-R in lenalidomide-treated, lower-risk myelodysplastic syndrome patients with del(5q).

artículo científico publicado en 2014

Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry.

artículo científico publicado en 2015

Valuation of transfusion-free living in MDS: results of health utility interviews with patients

scientific article published on 08 September 2009

Vasculitis associated with myelodysplastic syndrome and chronic myelomonocytic leukemia: French multicenter case-control study

artículo científico publicado en 2020

Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience

artículo científico publicado en 2009

Vincristine efficacy and safety in treating immune thrombocytopenia: a retrospective study of 35 patients

artículo científico publicado en 2015

When can real-time quantitative RT-PCR effectively define molecular relapse in acute promyelocytic leukemia patients? (Results of the French Belgian Swiss APL Group).

artículo científico publicado en 2009

Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins

artículo científico publicado en 2015

[(9;11) (p21;q23) translocation: apropos of 2 new cases seen in acute undifferentiated monoblastic AML5a leukemia]

scientific article published on 01 January 1987

[Acute lymphoblastic leukemia, Burkitt-cell type, after Hodgkin's disease. Study of 2 cases]

artículo científico publicado en 1987

[Amyloidosis AL and chronic myelo-monocytic leukemia]

artículo científico publicado en 1994

[Autologous bone marrow graft in the initial treatment of follicular lymphomas in young high risk subjects. A new therapeutic approach]

artículo científico publicado en 1991

[Chronic myeloid leukemia: from cytogenetics to molecular biology]

artículo científico publicado en 1990

[Congenital asplenia, a differential diagnosis of essential thrombocythemia]

artículo científico publicado en 1993

[Cytogenetics of myelodysplastic syndromes]

artículo científico publicado en 1997

[Cytological diagnosis of myelodysplastic syndromes. Apropos of 200 cases]

artículo científico publicado en 1987

[Cytosine-arabinoside in high doses in refractory acute granulocytic leukemia. Apropos of 17 cases]

scientific article published on 01 January 1985

[Efficacy of pipobroman in the treatment of essential thrombocythemia]

artículo científico publicado en 1988

[Hemophagocytic syndrome associated with herpes simplex virus. Apropos of a case with a fatal outcome]

artículo científico publicado en 1986

[Hepatic lymphoma simulating glycogenosis]

artículo científico publicado en 1986

[Hypomethylating agents for the treatment of myelodysplastic syndromes]

scientific article published on 01 August 2011

[Ineffective erythropoiesis of immunologic origin with free bilirubin jaundice in an elderly subject]

scientific article published on 01 January 1987

[Influence of pregnancy on the development of Hodgkin's disease]

artículo científico publicado en 1988

[Large B cell lymphoma of the mediastinum. 6 cases].

artículo científico publicado en 1989

[Molecular abnormalities and clonality in myelodysplastic syndromes]

artículo científico publicado en 1997

[Primary cardiac lymphoma. A new case]

artículo científico publicado en 1990

[Prognostic factors in myelodysplasia syndromes]

artículo científico publicado en 2002

[Role of double induction in the treatment of acute myeloblastic leukemia in the adult: intermediate results of protocol LAM90]

scientific article published on 01 July 1994

[Sequential chemotherapy with or without GM-CSF in acute myeloid leukemia (AML) in the advanced phase: current status of protocols EMA 86 and EMA 91]

scientific article published on 01 July 1994

[Systemic diseases in myelodysplastic syndromes]

scientific article published on 01 January 1995

[T-cell leukemia and lymphoma]

artículo científico publicado en 1987

[p53 and hematologic malignancies]

artículo científico publicado en 1997

bcl-2 expression in myelodysplastic syndromes and its correlation with hematological features, p53 mutations and prognosis

artículo científico publicado en 1995

de novo myelodysplastic syndromes in adults aged 50 or less. A report on 37 cases

artículo científico publicado en 1990

gamma-ray irradiation induces B7.1 expression in myeloid leukaemic cells.

artículo científico publicado en 2000

mutation is not associated with prolonged complete remission in acute myeloid leukemia patients treated with hypomethylating agents

scholarly article by Pedro Henrique Prata et al published October 2018 in Haematologica

p16 gene homozygous deletions in acute lymphoblastic leukemia

scientific article published on 01 February 1995

p16(INK4a) immunocytochemical analysis is an independent prognostic factor in childhood acute lymphoblastic leukemia

artículo científico publicado en 2002

p16ink4a gene and hematological malignancies.

artículo científico publicado en 1996

p190 bcr-abl rearrangement: a secondary cytogenetic event in some chronic myeloid disorders?

artículo científico publicado en 1999

p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies

artículo científico publicado en 1994

p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q).

artículo científico publicado en 2014

pVAX14DNA-mediated add-on immunotherapy combined with arsenic trioxide and all-trans retinoic acid targeted therapy effectively increases the survival of acute promyelocytic leukemia mice

artículo científico publicado en 2015

‘Corrigendum to “Chronic myelomonocytic leukemia: Myelodysplastic or myeloproliferative?” [Best Pract Res Clin Haematol (2013) 387–400]’

scholarly article published in Best Practice and Research: Clinical Haematology

Eficacia de la azacitidina en comparación con los regímenes de atención convencionales en el tratamiento de los síndromes mielodisplásicos de mayor riesgo: un estudio de fase III, aleatorizado, abierto

artículo científico publicado en 2009