Lista de obras - Jacques Colinge - Dominio Público Uruguay

13 Functional Proteomics of Innate Immunity Signalling

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.

artículo científico publicado en 2016

A Surface Biotinylation Strategy for Reproducible Plasma Membrane Protein Purification and Tracking of Genetic and Drug-Induced Alterations.

artículo científico publicado en 2015

A Web Resource for Improved Analysis of AP-MS Protein Interaction Data

artículo científico publicado en 2013

A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.

artículo científico publicado en 2015

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

artículo científico publicado en 2010

A chemical biology approach identifies AMPK as a modulator of melanoma oncogene MITF.

artículo científico publicado en 2013

A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.

artículo científico publicado en 2011

A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor

artículo científico publicado en 2017

A comparative proteomic study of human skin suction blister fluid from healthy individuals using immunodepletion and iTRAQ labeling

artículo científico publicado en 2012

A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib

artículo científico publicado en 2010

A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies

artículo científico publicado en 2013

A reversible gene trap collection empowers haploid genetics in human cells

artículo científico publicado en 2013

A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL

artículo científico publicado en 2013

A time-resolved molecular map of the macrophage response to VSV infection

artículo científico publicado en 2016

Acid elution and one-dimensional shotgun analysis on an Orbitrap mass spectrometer: an application to drug affinity chromatography.

artículo científico publicado en 2009

Affinity purification strategies for proteomic analysis of transcription factor complexes.

artículo científico publicado en 2013

An R package for generic modular response analysis and its application to estrogen and retinoic acid receptor crosstalk

artículo científico publicado en 2021

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

artículo científico publicado en 2011

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

artículo científico publicado en 2009

Application of modular response analysis to medium- to large-size biological systems

artículo científico publicado en 2022

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

artículo científico publicado en 2016

Assessing peptide de novo sequencing algorithms performance on large and diverse data sets.

artículo científico publicado en 2007

Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity.

artículo científico publicado en 2014

Building and exploring an integrated human kinase network: global organization and medical entry points.

artículo científico publicado en 2014

CD14 is a coreceptor of Toll-like receptors 7 and 9. ⬇️

artículo científico publicado en 2010

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

artículo científico publicado en 2014

CLOUD – CeMM library of unique drugs.

artículo científico publicado en 2012

Cell-Cycle Regulation Accounts for Variability in Ki-67 Expression Levels.

artículo científico publicado en 2017

Charting the molecular network of the drug target Bcr-Abl

artículo científico publicado en 2009

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

scientific article published on 24 August 2007

Clinical significance of genetic aberrations in secondary acute myeloid leukemia

artículo científico publicado en 2012

Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma

artículo científico

Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era.

artículo científico publicado en 2017

Deconvolution of targeted protein-protein interaction maps.

artículo científico publicado en 2012

Detecting the impact of sequencing errors on SAGE data.

artículo científico publicado en 2001

Differential proteomics via probabilistic peptide identification scores

scientific article published on 01 January 2005

Distinct oncogenes drive different genome and epigenome alterations in human mammary epithelial cells

scientific article published on 10 June 2019

Distinct oncogenes drive distinct genome and epigenome alterations in human mammary epithelial cells

Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency

artículo científico publicado en 2014

Epigenetik in der Onkologie

Experimental characterization of the human non-sequence-specific nucleic acid interactome

artículo científico publicado en 2013

Experiments in searching small proteins in unannotated large eukaryotic genomes

scientific article published on 01 January 2005

Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia.

artículo científico publicado en 2017

Functional dissection of the TBK1 molecular network

artículo científico publicado en 2011

Gene essentiality and synthetic lethality in haploid human cells

scientific journal article

General statistical modeling of data from protein relative expression isobaric tags.

artículo científico publicado en 2011

Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions

scientific article published on 18 October 2016

Germline RBBP6 mutations in familial myeloproliferative neoplasms.

artículo científico publicado en 2015

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

artículo científico publicado en 2016

High-performance peptide identification by tandem mass spectrometry allows reliable automatic data processing in proteomics.

artículo científico publicado en 2004

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

artículo científico publicado en 2011

Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics

artículo científico publicado en 2014

Improved peptide charge state assignment.

artículo científico publicado en 2003

In Vivo Large-Scale Mapping of Protein Turnover in Human Cerebrospinal Fluid

artículo científico publicado en 2019

In vitro and in silico processes to identify differentially expressed proteins

artículo científico publicado en 2004

InSilicoSpectro: an open-source proteomics library.

artículo científico publicado en 2006

Industrial-scale proteomics: from liters of plasma to chemically synthesized proteins

artículo científico publicado en 2004

Initial characterization of the human central proteome

artículo científico publicado en 2011

Interactome of two diverse RNA granules links mRNA localization to translational repression in neurons.

artículo científico publicado en 2013

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

artículo científico publicado en 2013

Introduction to computational proteomics

artículo científico publicado en 2007

Isobar(PTM): a software tool for the quantitative analysis of post-translationally modified proteins

artículo científico publicado en 2013

MASPECTRAS 2: An integration and analysis platform for proteomic data.

artículo científico publicado en 2010

Machine Learning-Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening

scientific article published on 29 July 2020

MetaBlasts: tracing protein tyrosine phosphatase gene family roots from Man to Drosophila melanogaster and Caenorhabditis elegans genomes.

artículo científico publicado en 2000

Multiple and sequential data acquisition method: an improved method for fragmentation and detection of cross-linked peptides on a hybrid linear trap quadrupole Orbitrap Velos mass spectrometer.

artículo científico publicado en 2013

NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation

artículo científico publicado en 2014

Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma

artículo científico publicado en 2020

OLAV-PMF: a novel scoring scheme for high-throughput peptide mass fingerprinting

artículo científico publicado en 2004

OLAV: towards high-throughput tandem mass spectrometry data identification

artículo científico publicado en 2003

Peptide fragment intensity statistical modeling

scientific article published on 23 August 2007

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

artículo científico publicado en 2013

Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling.

artículo científico publicado en 2015

Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ®-labelled specimens.

artículo científico

Quantitative proteomics of aqueous and vitreous fluid from patients with idiopathic epiretinal membranes

artículo científico publicado en 2012

SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics

scientific article published on 20 March 2020

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

artículo científico publicado en 2014

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage

artículo científico publicado en 2015

Systems Biology Analysis of Kinase Inhibitor Action in Leukemia Treatments ⬇️

artículo científico publicado el 7 de septiembre de 2013

Systems biology analysis of protein-drug interactions.

artículo científico publicado en 2011

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

artículo científico publicado en 2012

TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo

artículo científico publicado en 2010

TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens

artículo científico publicado en 2014

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

artículo científico publicado en 2015

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action† †Electronic supplementary information (ESI) available: Experimental, crystallographic, biological and mass spectrometric data, full list of pr

artículo científico publicado en 2015

Targeting a cell state common to triple-negative breast cancers

artículo científico publicado en 2015

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

artículo científico publicado en 2007

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

artículo científico publicado en 2013

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

scientific journal article

The Prognostic Impact of the Aryl Hydrocarbon Receptor (AhR) in Primary Breast Cancer Depends on the Lymph Node Status ⬇️

artículo científico publicado en 2019

The RNA-binding protein HuR/ELAVL1 regulates IFN-β mRNA abundance and the type I IFN response

artículo científico publicado en 2015

The chemokine interleukin-8 and the surface activation protein CD69 are markers for Bcr-Abl activity in chronic myeloid leukemia.

artículo científico publicado en 2008

The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities

scientific article published on 15 March 2020

The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia

artículo científico publicado en 2014

Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis

artículo científico publicado en 2021

Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer.

artículo científico publicado en 2010

Viral immune modulators perturb the human molecular network by common and unique strategies

artículo científico publicado en 2012

Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH

artículo científico publicado en 2014

[Radiomics: Definition and clinical development]

scientific article published on 03 September 2015

Lista de obras de Jacques Colinge

13 Functional Proteomics of Innate Immunity Signalling

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.

A Surface Biotinylation Strategy for Reproducible Plasma Membrane Protein Purification and Tracking of Genetic and Drug-Induced Alterations.

A Web Resource for Improved Analysis of AP-MS Protein Interaction Data

A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

A chemical biology approach identifies AMPK as a modulator of melanoma oncogene MITF.

A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.

A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor

A comparative proteomic study of human skin suction blister fluid from healthy individuals using immunodepletion and iTRAQ labeling

A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib

A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies

A reversible gene trap collection empowers haploid genetics in human cells

A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL

A time-resolved molecular map of the macrophage response to VSV infection

Acid elution and one-dimensional shotgun analysis on an Orbitrap mass spectrometer: an application to drug affinity chromatography.

Affinity purification strategies for proteomic analysis of transcription factor complexes.

An R package for generic modular response analysis and its application to estrogen and retinoic acid receptor crosstalk

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

Application of modular response analysis to medium- to large-size biological systems

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

Assessing peptide de novo sequencing algorithms performance on large and diverse data sets.

Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity.

Building and exploring an integrated human kinase network: global organization and medical entry points.

CD14 is a coreceptor of Toll-like receptors 7 and 9. ⬇️

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

CLOUD – CeMM library of unique drugs.

Cell-Cycle Regulation Accounts for Variability in Ki-67 Expression Levels.

Charting the molecular network of the drug target Bcr-Abl

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

Clinical significance of genetic aberrations in secondary acute myeloid leukemia

Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma

Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era.

Deconvolution of targeted protein-protein interaction maps.

Detecting the impact of sequencing errors on SAGE data.

Differential proteomics via probabilistic peptide identification scores

Distinct oncogenes drive different genome and epigenome alterations in human mammary epithelial cells

Distinct oncogenes drive distinct genome and epigenome alterations in human mammary epithelial cells

Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency

Epigenetik in der Onkologie

Experimental characterization of the human non-sequence-specific nucleic acid interactome

Experiments in searching small proteins in unannotated large eukaryotic genomes

Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia.

Functional dissection of the TBK1 molecular network

Gene essentiality and synthetic lethality in haploid human cells

General statistical modeling of data from protein relative expression isobaric tags.

Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions

Germline RBBP6 mutations in familial myeloproliferative neoplasms.

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

High-performance peptide identification by tandem mass spectrometry allows reliable automatic data processing in proteomics.

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics

Improved peptide charge state assignment.

In Vivo Large-Scale Mapping of Protein Turnover in Human Cerebrospinal Fluid

In vitro and in silico processes to identify differentially expressed proteins

InSilicoSpectro: an open-source proteomics library.

Industrial-scale proteomics: from liters of plasma to chemically synthesized proteins

Initial characterization of the human central proteome

Interactome of two diverse RNA granules links mRNA localization to translational repression in neurons.

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

Introduction to computational proteomics

Isobar(PTM): a software tool for the quantitative analysis of post-translationally modified proteins

MASPECTRAS 2: An integration and analysis platform for proteomic data.

Machine Learning-Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening

MetaBlasts: tracing protein tyrosine phosphatase gene family roots from Man to Drosophila melanogaster and Caenorhabditis elegans genomes.

Multiple and sequential data acquisition method: an improved method for fragmentation and detection of cross-linked peptides on a hybrid linear trap quadrupole Orbitrap Velos mass spectrometer.

NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation

Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma

OLAV-PMF: a novel scoring scheme for high-throughput peptide mass fingerprinting

OLAV: towards high-throughput tandem mass spectrometry data identification

Peptide fragment intensity statistical modeling

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling.

Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ®-labelled specimens.

Quantitative proteomics of aqueous and vitreous fluid from patients with idiopathic epiretinal membranes

SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage