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Lista de obras de Allan Randrup Thomsen

A 'Furry-Tale' of Zika Virus Infection: What Have We Learned from Animal Models?

artículo científico publicado en 2019

A New In Vivo Model to Study Protective Immunity to Zika Virus Infection in Mice With Intact Type I Interferon Signaling

artículo científico publicado en 2018

A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice

scientific article published on 15 July 2020

A new theory of cytotoxic T-lymphocyte memory: implications for HIV treatment.

artículo científico publicado en 2000

A new vaccination strategy to trigger specific CD4 T-cell response in chronic viral infection

artículo científico publicado en 2017

A systematic, unbiased mapping of CD8+ and CD4+ T cell epitopes in Yellow Fever vaccinees

artículo científico publicado en 2020

Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination

artículo científico publicado en 2017

Adenoviral vaccination combined with CD40 stimulation and CTLA-4 blockage can lead to complete tumor regression in a murine melanoma model

article

Adenovirus-based vaccine against Listeria monocytogenes: extending the concept of invariant chain linkage

artículo científico publicado en 2013

Agonistic anti-CD40 antibody profoundly suppresses the immune response to infection with lymphocytic choriomeningitis virus

artículo científico publicado en 2007

Alpha 4 integrin directs virus-activated CD8+ T cells to sites of infection

artículo científico publicado en 1995

An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity

scientific journal article

An innate antiviral pathway acting before interferons at epithelial surfaces

artículo científico publicado en 2015

Analysis of adenovirus-induced immunity to infection with Listeria monocytogenes: Fading protection coincides with declining CD8 T cell numbers and phenotypic changes

artículo científico publicado en 2018

Analysis of the Capacity to Produce IL-3 in Murine AIDS

article

Breakdown of blood-brain barrier function in the murine lymphocytic choriomeningitis virus infection mediated by virus-specific CD8+ T cells

artículo científico publicado en 1991

Broadening CD4+ and CD8+ T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes

artículo científico publicado en 2017

CCR2+ and CCR5+ CD8+ T cells increase during viral infection and migrate to sites of infection

artículo científico publicado en 2000

CD11b expression as a marker to distinguish between recently activated effector CD8+ T cells and memory cells

scientific article published on 01 April 2001

CD4 and CD8 T cell responses to the M. tuberculosis Ag85B-TB10.4 promoted by adjuvanted subunit, adenovector or heterologous prime boost vaccination

artículo científico publicado en 2009

CD4(+) T cell-mediated protection against a lethal outcome of systemic infection with vesicular stomatitis virus requires CD40 ligand expression, but not IFN-gamma or IL-4.

artículo científico publicado en 1999

CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus.

artículo científico publicado en 1998

CD8+ T cells are crucial for the ability of congenic normal mice to reject highly immunogenic sarcomas induced in nude mice with 3-methylcholanthrene

scientific article published on 01 August 2000

CD8+ T cells complement antibodies in protecting against yellow fever virus

artículo científico publicado en 2014

CXC chemokine receptor 3 expression increases the disease-inducing potential of CD4+ CD25− T cells in adoptive transfer colitis

CXCL10 is the key ligand for CXCR3 on CD8+ effector T cells involved in immune surveillance of the lymphocytic choriomeningitis virus-infected central nervous system

artículo científico publicado en 2006

CXCL10/CXCR3 signaling in glia cells differentially affects NMDA-induced cell death in CA and DG neurons of the mouse hippocampus

artículo científico publicado en 2011

CXCR3 directs antigen-specific effector CD4+ T cell migration to the lung during parainfluenza virus infection

artículo científico publicado en 2009

Characterization of virus-primed CD8+ T cells with a type 1 cytokine profile

artículo científico publicado en 1996

Chemokine Expression in Murine RPE/Choroid in Response to Systemic Viral Infection and Elevated Levels of Circulating Interferon-γ

artículo científico publicado en 2019

Circulating intercellular adhesion molecule-1 (ICAM-1) as an early and sensitive marker for virus-induced T cell activation

artículo científico publicado en 1995

Class I gene regulation of haplotype preference may influence antiviral immunity in vivo

artículo científico publicado en 1989

Clearance of virus by T lymphocytes mediating delayed type hypersensitivity

artículo científico publicado en 1987

Co-expression of tumor antigen and interleukin-2 from an adenoviral vector augments the efficiency of therapeutic tumor vaccination

artículo científico publicado en 2014

Co-ordinating innate and adaptive immunity to viral infection: mobility is the key.

artículo científico publicado en 2009

Combined local and systemic immunization is essential for durable T-cell mediated heterosubtypic immunity against influenza A virus

artículo científico publicado en 2016

Commentary: Endogenous glucocorticoids control host resistance to viral infection through tissue-specific regulation of PD-1 expression on NK cells

artículo científico publicado en 2018

Comparison of vaccine-induced effector CD8 T cell responses directed against self- and non-self-tumor antigens: implications for cancer immunotherapy

artículo científico publicado en 2013

Compromised virus control and augmented perforin-mediated immunopathology in IFN-gamma-deficient mice infected with lymphocytic choriomeningitis virus

artículo científico publicado en 1999

Concanavalin A-induced activation of lymphocytic choriomeningitis virus memory lymphocytes into specifically cytotoxic T cells ⬇️

artículo científico publicado el 1 de diciembre de 1977

Concanavalin A-mediated in vitro activation of a secondary cytotoxic T-cell response in virus-primed splenocytes

artículo científico publicado en 1980

Cooperation of B cells and T cells is required for survival of mice infected with vesicular stomatitis virus

artículo científico publicado en 1997

Corrigendum to “Interleukin-21 mRNA expression during virus infections” [Cytokine 33;2006:41–5]

scholarly article published in Cytokine

Cytokine production by virus-specific CD8(+) T cells varies with activation state and localization, but not with TCR avidity

artículo científico publicado en 2004

DNA fusion gene vaccines.

scientific article published on February 2010

Deficient CD4+ T cell priming and regression of CD8+ T cell functionality in virus-infected mice lacking a normal B cell compartment

artículo científico publicado en 2003

Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin

scientific journal article

Depletion of CD4+ T cells precipitates immunopathology in immunodeficient mice infected with a noncytocidal virus

artículo científico publicado en 2001

Different Tc response profiles are associated with survival in the murine lymphocytic choriomeningitis virus infection

artículo científico publicado en 1987

Different isotype profiles of virus-specific antibodies in acute and persistent lymphocytic choriomeningitis virus infection in mice

artículo científico publicado en 1985

Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery

artículo científico publicado en 2012

Does programmed CTL proliferation optimize virus control?

artículo científico publicado en 2005

EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies

artículo científico publicado en 2016

Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors.

artículo científico publicado en 2016

Effect of the CTL proliferation program on virus dynamics

artículo científico publicado en 2005

Effector CD8 T Cell-Dependent Zika Virus Control in the CNS: A Matter of Time and Numbers

scientific article published on 18 August 2020

Efficient Control of Zika Virus Infection Induced by a Non-Replicating Adenovector Encoding Zika Virus NS1/NS2 Antigens Fused to the MHC Class II-Associated Invariant Chain

scientific article published in 2021

Efficient T-cell surveillance of the CNS requires expression of the CXC chemokine receptor 3.

artículo científico publicado en 2004

Enhanced and Sustained CD8+ T Cell Responses with an Adenoviral Vector-Based Hepatitis C Virus Vaccine Encoding NS3 Linked to the MHC Class II Chaperone Protein Invariant Chain ⬇️

artículo científico publicado el 21 de enero de 2011

Epicutaneous exposure to nickel induces nickel allergy in mice via a MyD88-dependent and interleukin-1-dependent pathway

scholarly article by Marie T. Vennegaard et al published 18 July 2014 in Contact Dermatitis

Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice

artículo científico publicado en 1996

Experimental Hyperactivity of the Endolymphatic Sac

article

Expression and functional importance of collagen-binding integrins, alpha 1 beta 1 and alpha 2 beta 1, on virus-activated T cells

artículo científico publicado en 2003

Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis.

artículo científico publicado en 2009

Expression of type 3 complement receptor on activated CD8+ T cells facilitates homing to inflammatory sites

artículo científico publicado en 1994

Fatal meningitis following lymphocytic choriomeningitis virus infection reflects delayed-type hypersensitivity rather than cytotoxicity

artículo científico publicado en 1983

Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade

artículo científico publicado en 2009

Functional epistasis on a common MHC haplotype associated with multiple sclerosis

artículo científico publicado en 2006

Fusion of a viral antigen to invariant chain leads to augmented T-cell immunity and improved protection in gene-gun DNA-vaccinated mice

article

Gene-gun DNA vaccination aggravates respiratory syncytial virus-induced pneumonitis.

artículo científico publicado en 2004

High numbers of IL-2-producing CD8+ T cells during viral infection: correlation with stable memory development

artículo científico publicado en 2002

High-dose survival in the lymphocytic choriomeningitis virus infection is accompanied by suppressed DTH but unaffected T-cell cytotoxicity

artículo científico publicado en 1985

Host factors influencing viral persistence.

artículo científico publicado en 2000

Host-microbe relations

IFNγ and perforin cooperate to control infection and prevent fatal pathology during persistent gammaherpesvirus infection in mice.

artículo científico publicado en 2014

Impaired virus control and severe CD8+ T-cell-mediated immunopathology in chimeric mice deficient in gamma interferon receptor expression on both parenchymal and hematopoietic cells

artículo científico publicado en 2005

In vitro propagation and dynamics of T cells from skin biopsies by methods using interleukins-2 and -4 or anti-CD3/CD28 antibody-coated microbeads

artículo científico publicado en 2010

Incomplete effector/memory differentiation of antigen-primed CD8+ T cells in gene gun DNA-vaccinated mice

artículo científico publicado en 2003

Increased immunogenicity and protective efficacy of influenza M2e fused to a tetramerizing protein

artículo científico publicado en 2012

Inducible nitric-oxide synthase plays a minimal role in lymphocytic choriomeningitis virus-induced, T cell-mediated protective immunity and immunopathology

artículo científico publicado en 1999

Interleukin-21 mRNA expression during virus infections

artículo científico publicado en 2006

Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes

artículo científico publicado en 2009

Knocking out IL-6 by vaccination

artículo científico publicado en 2004

Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo

artículo científico publicado en 2006

Lipocalin-2 Functions as Inhibitor of Innate Resistance to

Local Antigen Encounter Is Essential for Establishing Persistent CD8 T-Cell Memory in the CNS

artículo científico publicado en 2019

Lymphocytic choriomeningitis virus infection is associated with long-standing perturbation of LFA-1 expression on CD8+ T cells

artículo científico publicado en 1995

Lymphocytic choriomeningitis virus-induced central nervous system disease: a model for studying the role of chemokines in regulating the acute antiviral CD8+ T-cell response in an immune-privileged organ

artículo científico publicado en 2008

MEK kinase 1 is a negative regulator of virus-specific CD8(+) T cells

artículo científico publicado en 2006

MHC Class II-Associated Invariant Chain Linkage of Antigen Dramatically Improves Cell-Mediated Immunity Induced by Adenovirus Vaccines

article published in 2008

MHC and non-MHC genes regulate elimination of lymphocytic choriomeningitis virus and antiviral cytotoxic T lymphocyte and delayed-type hypersensitivity mediating T lymphocyte activity in parallel.

artículo científico publicado en 1989

MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans

scientific article published on 01 June 2020

Midline 1 directs lytic granule exocytosis and cytotoxicity of mouse killer T cells

artículo científico publicado en 2014

Migration of activated CD8(+) T lymphocytes to sites of viral infection does not require endothelial selectins

artículo científico publicado en 2000

Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication.

artículo científico publicado en 2017

Mucosal immunization with recombinant adenoviral vectors expressing murine gammaherpesvirus-68 genes M2 and M3 can reduce latent viral load

article

MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7.

artículo científico publicado en 2012

Non-MHC genes influence virus clearance through regulation of the antiviral T-cell response: correlation between virus clearance and Tc and Td activity in segregating backcross progeny

artículo científico publicado en 1994

Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection

artículo científico publicado en 2018

Opposing effects of CXCR3 and CCR5 deficiency on CD8+ T cell-mediated inflammation in the central nervous system of virus-infected mice

artículo científico publicado en 2005

PB1 as a potential target for increasing the breadth of T-cell mediated immunity to Influenza A.

artículo científico publicado en 2016

Perforin and IFN-gamma do not significantly regulate the virus-specific CD8+ T cell response in the absence of antiviral effector activity

artículo científico publicado en 2004

Perforin-deficient CD8+ T cells mediate fatal lymphocytic choriomeningitis despite impaired cytokine production

artículo científico publicado en 2006

Pre-existing vector immunity does not prevent replication deficient adenovirus from inducing efficient CD8 T-cell memory and recall responses

artículo científico publicado en 2012

Priming of CD8 T cells by adenoviral vectors is critically dependent on B7 and dendritic cells but only partially dependent on CD28 ligation on CD8 T cells

artículo científico publicado en 2014

Qualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: not as bad as their reputation.

artículo científico publicado en 2013

Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination

artículo científico publicado en 2010

Quantification of B16 melanoma cells in lungs using triplex Q-PCR--a new approach to evaluate melanoma cell metastasis and tumor control.

artículo científico publicado en 2014

Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8+ T cells

artículo científico publicado en 2016

Rapid and sustained CD4+ T-cell-independent immunity from adenovirus-encoded vaccine antigens

artículo científico publicado en 2007

Regulation and function of host defences in the murine lymphocytic choriomeningitis virus infection.

artículo científico publicado en 1993

Regulation of T cell migration during viral infection: role of adhesion molecules and chemokines

artículo científico publicado en 2003

Replication deficient human adenovirus vector serotype 19a/64: Immunogenicity in mice and female cynomolgus macaques

scholarly article by Emeline Ragonnaud et al published 1 October 2018 in Vaccine

Role of CD28 co-stimulation in generation and maintenance of virus-specific T cells

artículo científico publicado en 2002

Role of CD40 Ligand and CD28 in Induction and Maintenance of Antiviral CD8+ Effector T Cell Responses

article

Role of interferon-gamma in the pathogenesis of LCMV-induced meningitis: unimpaired leucocyte recruitment, but deficient macrophage activation in interferon-gamma knock-out mice

artículo científico publicado en 1998

Role of macrophage inflammatory protein-1alpha in T-cell-mediated immunity to viral infection

artículo científico publicado en 2003

Role of very late antigen-1 in T-cell-mediated immunity to systemic viral infection

artículo científico publicado en 2006

Seasonal Influenza Split Vaccines Confer Partial Cross-Protection against Heterologous Influenza Virus in Ferrets When Combined with the CAF01 Adjuvant

artículo científico publicado en 2017

Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion

artículo científico

Sensitization to Lipopolysaccharide in Mice with Asymptomatic Viral Infection: Role of T Cell‐Dependent Production of Interferon–γ

article

Single-epitope DNA vaccination prevents exhaustion and facilitates a broad antiviral CD8+ T cell response during chronic viral infection

artículo científico publicado en 2004

Soluble tumour necrosis factor (TNF)-receptor levels in serum as markers of anti-viral host reactivity

scientific article published on 01 May 1999

Stem cells

Studies on the role of mononuclear phagocytes in resistance to acute lymphocytic choriomeningitis virus infection

artículo científico publicado en 1983

Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways

artículo científico publicado en 2014

T-Cell Responsiveness to LCMV Segregates as a Single Locus in Crosses between BALB/cA and C.B-17 Mice. Evidence for Regulation by a Gene Outside the Igh Region

article

T-cell effector function and unresponsiveness in the murine lymphocytic choriomeningitis virus infection. I. On the mechanism of a selective suppression of the virus-specific delayed-type hypersensitivity response

artículo científico publicado en 1986

T-cell effector function and unresponsiveness in the murine lymphocytic choriomeningitis virus infection. II. Delayed-type hypersensitivity unresponsiveness reflects a defective differentiation from TD precursor to effector cell

artículo científico publicado en 1986

T-cell intrinsic expression of MyD88 is required for sustained expansion of the virus-specific CD8+ T-cell population in LCMV-infected mice

artículo científico publicado en 2009

TCR down-regulation controls virus-specific CD8+ T cell responses

artículo científico publicado en 2008

TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain

artículo científico publicado en 2008

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice

artículo científico publicado en 2012

Targeting of non-dominant antigens as a vaccine strategy to broaden T-cell responses during chronic viral infection

artículo científico publicado en 2015

The Susceptibility to Cytotoxic T Lymphocyte Mediated Lysis of Chemically Induced Sarcomas from Immunodeficient and Normal Mice

scientific article published on 01 January 1997

The availability of a functional tumor targeting T-cell repertoire determines the anti-tumor efficiency of combination therapy with anti-CTLA-4 and anti-4-1BB antibodies

artículo científico publicado en 2013

The combination of major histocompatibility complex (MHC) and non-MHC genes influences murine lymphocytic choriomeningitis virus pathogenesis

artículo científico publicado en 1989

The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung

artículo científico publicado en 2017

The complementary roles of cellular and humoral immunity in resistance to re-infection with LCM virus.

artículo científico publicado en 1988

The dual role of lymphocytic choriomeningitis virus-specific antibodies

artículo científico publicado en 1986

The effect of lymphocytic choriomeningitis virus-induced suppression of the delayed-type hypersensitivity reaction on virus clearance and pathogenicity

artículo científico publicado en 1986

The importance of lytic and nonlytic immune responses in viral infections

article

The murine gammaherpesvirus-68 chemokine-binding protein M3 inhibits experimental autoimmune encephalomyelitis

artículo científico publicado en 2010

The role of CC chemokine receptor 5 in antiviral immunity

scientific article published on 01 February 2002

The role of CD4+ T cells in cell-mediated immunity to LCMV: studies in MHC class I and class II deficient mice

artículo científico publicado en 1994

The role of CD80/CD86 in generation and maintenance of functional virus-specific CD8+ T cells in mice infected with lymphocytic choriomeningitis virus

artículo científico publicado en 2010

The timing of the immune response in relation to virus growth determines the outcome of the LCM infection

artículo científico publicado el 1 de febrero de 1979

The virus-encoded chemokine vMIP-II inhibits virus-induced Tc1-driven inflammation

artículo científico publicado en 2003

Vaccination against Lymphocytic Choriomeningitis Virus Infection in MHC Class II-Deficient Mice ⬇️

artículo científico publicado el 28 de febrero de 2011

Vaccination with IL-6 analogues induces autoantibodies to IL-6 and influences experimentally induced inflammation

article by Pia Galle et al published December 2007 in International Immunopharmacology

Vaccination with Replication Deficient Adenovectors Encoding YF-17D Antigens Induces Long-Lasting Protection from Severe Yellow Fever Virus Infection in Mice

artículo científico publicado en 2016

Vaccination with an adenoviral vector encoding the tumor antigen directly linked to invariant chain induces potent CD4+T-cell-independent CD8+T-cell-mediated tumor control

scholarly article by Maria R. Sorensen et al published October 2009 in European Journal of Immunology

Vaccine Targeting of Subdominant CD8+ T Cell Epitopes Increases the Breadth of the T Cell Response upon Viral Challenge, but May Impair Immediate Virus Control

artículo científico publicado en 2016

Viral activities from a quantitative slant

artículo científico publicado en 2001

Virus elimination in acute lymphocytic choriomeningitis virus infection. Correlation with virus-specific delayed-type hypersensitivity rather than cytotoxicity

artículo científico publicado en 1983

Virus-activated T cells regulate expression of adhesion molecules on endothelial cells in sites of infection

artículo científico publicado en 1995

Virus-based immunotherapy of cancer: what do we know and where are we going?

artículo científico publicado en 2007

Virus-induced T cell activation and the inflammatory response.

artículo científico publicado en 1998

Virus-induced polyclonal T cell activation is followed by apoptosis: partitioning of CD8+ T cells based on alpha 4 integrin expression

artículo científico publicado en 1996

[Avian influenza and perspectives on vaccination against pandemic influenza].

artículo científico publicado en 2008

[HPV vaccination – should/should not?] ⬇️

artículo científico publicado en 2015

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