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Lista de obras de Caroline Dive

A Pilot Study Assessing the Prognostic Value of CK18 and nDNA Biomarkers in Severe Sepsis Patients

A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers

artículo científico publicado en 2013

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs

artículo científico publicado en 2022

A hierarchical statistical modeling approach to analyze proteomic isobaric tag for relative and absolute quantitation data

artículo científico publicado en 2013

A new Alliance: biomedical societies in Europe unite to support research

artículo científico publicado en 2011

A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours

artículo científico publicado en 2013

A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker.

artículo científico publicado en 2011

A proof-of-principle gel-free proteomics strategy for the identification of predictive biomarkers for the onset of pre-eclampsia

artículo científico publicado en 2009

A small molecule inhibitor of XIAP induces apoptosis and synergises with vinorelbine and cisplatin in NSCLC.

artículo científico publicado en 2009

A study to investigate dose escalation of doxorubicin in ABVD chemotherapy for Hodgkin lymphoma incorporating biomarkers of response and toxicity

scientific article published on 17 October 2013

AZD3514, an oral selective androgen receptor down-regulator in patients with castration-resistant prostate cancer - results of two parallel first-in-human phase I studies

artículo científico publicado en 2015

Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity

artículo científico publicado en 2006

Activation of the Abelson tyrosine kinase activity is associated with suppression of apoptosis in hemopoietic cells

artículo científico publicado en 1993

Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer

artículo científico publicado en 2013

Alliance for biomedical research in Europe

artículo científico publicado en 2011

An integrated characterization of serological, pathological, and functional events in doxorubicin-induced cardiotoxicity

artículo científico publicado en 2014

Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry

artículo científico publicado en 1992

Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches

article

Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer

scientific article published on 12 August 2019

Analytical validation of BRAF mutation testing from circulating free DNA using the amplification refractory mutation testing system

artículo científico

Apoptosis and cancer chemotherapy

scientific article published on 01 November 2001

Apoptosis pathway-targeted drugs--from the bench to the clinic

artículo científico publicado en 2004

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

artículo científico publicado en 1993

Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma.

artículo científico publicado en 2015

Application of the β-expectation tolerance interval to method validation of the M30 and M65 ELISA cell death biomarker assays

artículo científico publicado en 2011

Assessment of circulating biomarkers for potential pharmacodynamic utility in patients with lymphoma

artículo científico publicado en 2011

Assessment of diurnal changes and confounding factors that affect circulating cell death biomarker levels: a short communication.

artículo científico publicado en 2013

Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

scientific article published on 01 July 2019

Avoidance of apoptosis as a mechanism of drug resistance

artículo científico publicado el 1 de enero de 1997

BMX acts downstream of PI3K to promote colorectal cancer cell survival and pathway inhibition sensitizes to the BH3 mimetic ABT-737.

artículo científico

Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

artículo científico publicado en 2001

Biological mechanisms linking obesity and cancer risk: new perspectives

artículo científico publicado en 2010

Biology and clinical relevance of circulating tumour cells

artículo científico publicado en 2012

Biomarker method validation in anticancer drug development

artículo científico publicado en 2007

Biomarker utility of circulating tumor cells in metastatic cutaneous melanoma

artículo científico publicado en 2012

Biomarkers for small cell lung cancer: neuroendocrine, epithelial and circulating tumour cells

artículo científico

Biomarkers of angiogenesis and their role in the development of VEGF inhibitors

artículo científico publicado en 2010

Biomarkers of apoptosis

artículo científico publicado en 2008

Biomarkers of cell death applicable to early clinical trials

artículo científico

Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs

artículo científico publicado en 2009

Blood cells with reduced mitochondrial membrane potential and cytosolic cytochrome C can survive and maintain clonogenicity given appropriate signals to suppress apoptosis.

artículo científico publicado en 1998

Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts

artículo científico publicado en 2012

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

artículo científico publicado en 2016

Can flow cytoenzymology be applied to measure membrane-bound enzyme kinetics? Assessment by analysis of gamma-glutamyl transpeptidase activity

artículo científico publicado en 1993

Cancer Moonshot Connecting International Liquid Biopsy Efforts Through Academic Partnership

artículo científico publicado en 2017

Cediranib combined with carboplatin and paclitaxel in patients with metastatic or recurrent cervical cancer (CIRCCa): a randomised, double-blind, placebo-controlled phase 2 trial

artículo científico publicado en 2015

Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial

artículo científico publicado en 2015

Cell Death, Inflammation, Tumor Burden, and Proliferation Blood Biomarkers Predict Lung Cancer Radiotherapy Response and Correlate With Tumor Volume and Proliferation Imaging

artículo científico publicado en 2017

Cell Sensitivity Assays : Detection of Apoptotic Cells In Vitro Using the TUNEL Assay

artículo científico publicado en 1999

Cell cycle specific induction of HL-60 cell differentiation and apoptosis by mycophenolic acid

artículo científico publicado en 1997

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

artículo científico publicado en 1999

Cell sensitivity assays. Quantitative detection of apoptotic cells in vitro using the TUNEL assay

artículo científico publicado en 2001

Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

artículo científico publicado en 2001

Changes in intercellular junctions during apoptosis precede nuclear condensation or phosphatidylserine exposure on the cell surface

Characterization of cell volume loss in CEM-C7A cells during dexamethasone-induced apoptosis

article

Characterization of drug resistance mediated via the suppression of apoptosis by Abelson protein tyrosine kinase ⬇️

artículo científico publicado el 1 de agosto de 1995

Chronic hypoxia promotes hypoxia-inducible factor-1alpha-dependent resistance to etoposide and vincristine in neuroblastoma cells.

artículo científico publicado en 2006

Circulating Tumor Cell Enumeration in a Phase II Trial of a Four-Drug Regimen in Advanced Colorectal Cancer

artículo científico publicado en 2014

Circulating Tumor Cells Detected in the Tumor-Draining Pulmonary Vein Are Associated with Disease Recurrence after Surgical Resection of NSCLC.

artículo científico publicado en 2016

Circulating biomarkers in hepatocellular carcinoma

article

Circulating biomarkers of cell death after treatment with the BH-3 mimetic ABT-737 in a preclinical model of small-cell lung cancer

artículo científico publicado en 2008

Circulating tumor cells and CDX models as a tool for preclinical drug development

artículo científico publicado en 2017

Circulating tumor cells as a window on metastasis biology in lung cancer

artículo científico publicado en 2011

Circulating tumor cells, enumeration and beyond

artículo científico publicado en 2010

Circulating tumour cells as tumour biomarkers in melanoma: detection methods and clinical relevance

artículo científico publicado en 2014

Circulating tumour cells: their utility in cancer management and predicting outcomes

artículo científico publicado en 2010

Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53.

artículo científico publicado en 1998

Clinical Significance and Molecular Characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in Patients With Small-Cell Lung Cancer

article

Clinical evaluation of M30 and M65 ELISA cell death assays as circulating biomarkers in a drug-sensitive tumor, testicular cancer

artículo científico publicado en 2008

Clinical evaluation of a novel microfluidic device for epitope-independent enrichment of circulating tumour cells in patients with small cell lung cancer

artículo científico publicado en 2015

Clinical utility of circulating tumour cell detection in non-small-cell lung cancer

artículo científico publicado en 2013

Comparative effects of Bcl-2 over-expression and ZVAD.FMK treatment on dexamethasone and VP16-induced apoptosis in CEM cells

Comparison of doxycycline delivery methods for Tet-inducible gene expression in a subcutaneous xenograft model

artículo científico publicado en 2007

Comparison of phosphatidylinositol-3-kinase signalling within a panel of human colorectal cancer cell lines with mutant or wild-type PIK3CA.

artículo científico publicado en 2005

Consensus on precision medicine for metastatic cancers: a report from the MAP conference.

artículo científico publicado en 2016

Considerations for the use of plasma cytokeratin 18 as a biomarker in pancreatic cancer.

artículo científico publicado en 2010

Construction and characterization of multiple human colon cancer cell lines for inducibly regulated gene expression.

artículo científico publicado en 2005

Contribution of HIF-1 and drug penetrance to oxaliplatin resistance in hypoxic colorectal cancer cells.

artículo científico publicado en 2009

Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

artículo científico publicado en 2017

Current status and future potential of somatic mutation testing from circulating free DNA in patients with solid tumours

artículo científico publicado en 2010

Cytoplasmic acidification is not an effector mechanism of VP16 or DEX-induced apoptosis in CEM T leukaemia cells

artículo científico publicado en 1999

DNA-damaging agents induce both p53-dependent and p53-independent apoptosis in immature thymocytes

artículo científico publicado en 1996

Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

artículo científico publicado en 2001

Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study.

artículo científico publicado en 2009

Detection of PIK3CA mutations in circulating free DNA in patients with breast cancer

artículo científico

Development of a circulating miRNA assay to monitor tumor burden: From mouse to man

artículo científico publicado en 2015

Diagnostic Mutation Profiling and Validation of Non-Small-Cell Lung Cancer Small Biopsy Samples using a High Throughput Platform.

artículo científico publicado en 2015

Differences in resistance to 5-fluorouracil as a function of cell cycle delay and not apoptosis.

artículo científico publicado en 1995

Differential induction of etoposide-mediated apoptosis in human leukemia HL-60 and K562 cells

scientific article published on 01 October 1994

Differential sensitivity to the induction of apoptosis by cisplatin in proliferating and quiescent immature rat thymocytes is independent of the levels of drug accumulation and DNA adduct formation.

artículo científico publicado en 1994

Difluoro analogue of UCS15A triggers activation of exogenously expressed c-Src in HCT 116 human colorectal carcinoma cells

artículo científico publicado en 2007

Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value

artículo científico publicado en 2015

Distinct subclonal tumour responses to therapy revealed by circulating cell-free DNA.

artículo científico publicado en 2016

Down-regulation of XIAP by AEG35156 in paediatric tumour cells induces apoptosis and sensitises cells to cytotoxic agents

artículo científico publicado en 2011

Drug-target interactions: only the first step in the commitment to a programmed cell death? ⬇️

artículo científico publicado el 1 de julio de 1991

Dynamic CT in pancreatic lymphoma

artículo científico publicado en 1993

ERS is founding member of a new Alliance for Biomedical Research in Europe

artículo científico publicado en 2011

Effect of prolonged formalin fixation on immunohistochemical staining for the proliferation marker Ki67

Effects of cisplatin on the induction of apoptosis in proliferating hepatoma cells and nonproliferating immature thymocytes

artículo científico publicado en 1993

Epigenetic determinants of resistance to etoposide regulation of Bcl-X(L) and Bax by tumor microenvironmental factors

artículo científico publicado en 2000

Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer

article

Evaluation and validation of a robust single cell RNA-amplification protocol through transcriptional profiling of enriched lung cancer initiating cells.

artículo científico publicado en 2014

Evaluation of cell death mechanisms induced by the vascular disrupting agent OXi4503 during a phase I clinical trial

artículo científico publicado en 2012

Evaluation of circulating tumor cells and serological cell death biomarkers in small cell lung cancer patients undergoing chemotherapy

scientific article published on 23 July 2009

Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis

artículo científico publicado en 2004

Expression of pro-apoptotic Bfk isoforms reduces during malignant transformation in the human gastrointestinal tract

artículo científico publicado en 2005

Expression of the proapoptotic protein Bid is an adverse prognostic factor for radiotherapy outcome in carcinoma of the cervix.

artículo científico publicado en 2005

External quality assurance of circulating tumor cell enumeration using the CellSearch® system: A feasibility study

article

Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling

artículo científico publicado en 1999

Fit-for-purpose biomarker method validation for application in clinical trials of anticancer drugs

scientific article published on 05 October 2010

Fit-for-purpose biomarker method validation in anticancer drug development

scientific article published on 11 August 2010

Flow Cytometric Analysis of Steroidogenic Organelles in Differentiating Granulosa Cells1

artículo científico publicado en 1992

Further characterisation of the in situ terminal deoxynucleotidyl transferase (TdT) assay for the flow cytometric analysis of apoptosis in drug resistant and drug sensitive leukaemic cells.

artículo científico publicado en 1995

Generation of cells expressing improved doxycycline-regulated reverse transcriptional transactivator rtTA2S-M2.

artículo científico publicado en 2006

Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample.

artículo científico publicado en 2015

Germinal center-derived signals act with Bcl-2 to decrease apoptosis and increase clonogenicity of drug-treated human B lymphoma cells.

artículo científico publicado en 1997

Hypoxia-driven splicing into noncoding isoforms regulates the DNA damage response

artículo científico publicado en 2016

Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha

artículo científico publicado en 2013

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

scientific article published on April 2004

Hypoxic human cancer cells are sensitized to BH-3 mimetic–induced apoptosis via downregulation of the Bcl-2 protein Mcl-1.

artículo científico publicado en 2011

IAPs as a target for anticancer therapy.

artículo científico publicado en 2007

Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer

artículo científico publicado en 2016

Identification of early predictive imaging biomarkers and their relationship to serological angiogenic markers in patients with ovarian cancer with residual disease following cytotoxic therapy

artículo científico publicado en 2010

Imaging biomarker roadmap for cancer studies ⬇️

artículo científico publicado en 2016

Improved methodology for intracellular enzyme reaction and inhibition kinetics by flow cytometry

artículo científico publicado en 1987

In silico screening and biological evaluation of inhibitors of Src-SH3 domain interaction with a proline-rich ligand

artículo científico publicado en 2007

Increases in c-Src expression level and activity do not promote the growth of human colorectal carcinoma cells in vitro and in vivo

artículo científico publicado en 2006

Increases in c-Yes expression level and activity promote motility but not proliferation of human colorectal carcinoma cells

artículo científico publicado en 2007

Inducible EGFR T790M-mediated gefitinib resistance in non-small cell lung cancer cells does not modulate sensitivity to PI103 provoked autophagy

artículo científico publicado en 2010

Inhibition of FGFR2 and FGFR1 increases cisplatin sensitivity in ovarian cancer

artículo científico publicado en 2010

Inhibition of PI3K/BMX Cell Survival Pathway Sensitizes to BH3 Mimetics in SCLC.

artículo científico publicado en 2016

Inhibition of cellular esterases by the antitumour imidazotetrazines mitozolomide and temozolomide: demonstration by flow cytometry and conventional spectrofluorimetry

artículo científico publicado en 1989

Inhibition of intracellular esterases by antitumour chloroethylnitrosoureas

artículo científico publicado en 1988

Investigation of the mechanism of higher order chromatin fragmentation observed in drug-induced apoptosis.

artículo científico publicado en 1995

Is Serum or Plasma More Appropriate for Intersubject Comparisons in Metabolomic Studies? An Assessment in Patients with Small-Cell Lung Cancer

article

Is metabolism an important arbiter of anticancer activity of ether lipids? Metabolism of SRI 62-834 and hexadecylphosphocholine by [31P]-NMR spectroscopy and comparison of their cytotoxicities with those of their metabolites

artículo científico publicado en 1992

Isolation and Extraction of Circulating Tumor DNA from Patients with Small Cell Lung Cancer

artículo científico publicado en 2008

Issues on fit-for-purpose validation of a panel of ELISAs for application as biomarkers in clinical trials of anti-Angiogenic drugs.

artículo científico publicado en 2010

Liquid chromatography-mass spectrometry calibration transfer and metabolomics data fusion

artículo científico publicado en 2012

MCF-7 human mammary adenocarcinoma cell death in vitro in response to hormone-withdrawal and DNA damage

artículo científico publicado en 1995

Medical societies unite to support research in Europe

artículo científico publicado en 2011

Method validation and preliminary qualification of pharmacodynamic biomarkers employed to evaluate the clinical efficacy of an antisense compound (AEG35156) targeted to the X-linked inhibitor of apoptosis protein XIAP.

artículo científico publicado en 2006

Method validation of circulating tumour cell enumeration at low cell counts

artículo científico publicado en 2013

Mitochondrial membrane permeabilisation by Bax/Bak ⬇️

artículo científico publicado el 9 de mayo de 2003

Modulating sensitivity to drug-induced apoptosis: the future for chemotherapy?

artículo científico publicado en 2001

Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer

artículo científico publicado en 2016

Molecular analysis of circulating tumour cells-biology and biomarkers

artículo científico

Molecular analysis of single circulating tumour cells following long-term storage of clinical samples

artículo científico publicado en 2017

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

artículo científico publicado en 2019

Multi-level evidence that circulating CK18 is a biomarker of tumour burden in colorectal cancer ⬇️

artículo científico publicado en 2012

Multiparametric analysis of cell membrane permeability by two colour flow cytometry with complementary fluorescent probes

article

Multiparametric flow cytometry of the modulation of tumor cell membrane permeability by developmental antitumor ether lipid SRI 62-834 in EMT6 mouse mammary tumor and HL-60 human promyelocytic leukemia cells

artículo científico publicado en 1991

Multiplexed assays for detection of mutations in PIK3CA.

artículo científico publicado en 2008

Neuroendocrine and epithelial phenotypes in small-cell lung cancer: implications for metastasis and survival in patients

artículo científico publicado en 2013

Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models

artículo científico publicado en 2017

Non-genotoxic hepatocarcinogenesis in vitro: the FaO hepatoma line responds to peroxisome proliferators and retains the ability to undergo apoptosis

artículo científico publicado en 1993

Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma.

artículo científico publicado en 2013

Novel dynamic flow cytoenzymological determination of intracellular esterase inhibition by BCNU and related isocyanates

artículo científico publicado en 1987

Novel risk models for early detection and screening of ovarian cancer

artículo científico publicado en 2016

Novel therapeutic targets in lung cancer: Inhibitor of apoptosis proteins from laboratory to clinic

artículo científico publicado en 2007

Obesity and cancer: Pathophysiological and biological mechanisms

article

Obesity, insulin and chemoresistance in colon cancer

artículo científico publicado en 2011

Optimisation of an immunohistochemistry method for the determination of androgen receptor expression levels in circulating tumour cells

artículo científico publicado en 2014

Optimisation of circulating biomarkers of cell death for routine clinical use.

artículo científico publicado en 2008

Optimisation of immunofluorescence methods to determine MCT1 and MCT4 expression in circulating tumour cells

artículo científico publicado en 2015

Optimization of circulating biomarkers of obatoclax-induced cell death in patients with small cell lung cancer

artículo científico publicado en 2011

Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors.

artículo científico publicado en 2010

PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.

artículo científico publicado en 2008

PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumorigenesis by targeting multiple components of KRAS and NF-kB pathways

artículo científico publicado en 2017

PO-36 - Thrombin Inhibition Preoperatively (TIP) in early breast cancer, the first clinical trial of NOACs as an anti-cancer agent: trial methodology

artículo científico publicado en 2016

Parallel Evaluation of Circulating Tumor DNA and Circulating Tumor Cells in Metastatic Colorectal Cancer

artículo científico publicado en 2017

Pazopanib and Fosbretabulin in recurrent ovarian cancer (PAZOFOS): A multi-centre, phase 1b and open-label, randomised phase 2 trial

artículo científico publicado en 2020

Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1

Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors

artículo científico publicado en 2011

Phase I trial of AEG35156 administered as a 7-day and 3-day continuous intravenous infusion in patients with advanced refractory cancer

artículo científico publicado en 2009

Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer

artículo científico publicado en 2012

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

artículo científico publicado en 2017

Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer

artículo científico publicado en 2018

Polar fluorescein derivatives as improved substrate probes for flow cytoenzymological assay of cellular esterases

artículo científico publicado en 1988

Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3.

artículo científico publicado en 2003

Preclinical efficacy of the bioreductive alkylating agent RH1 against paediatric tumours.

artículo científico publicado en 2009

Preclinical evaluation of M30 and M65 ELISAs as biomarkers of drug induced tumor cell death and antitumor activity

artículo científico publicado en 2008

Prevalence and heterogeneity of circulating tumour cells in metastatic cutaneous melanoma

scientific article

Proapoptotic Bid binds to monolysocardiolipin, a new molecular connection between mitochondrial membranes and cell death

artículo científico publicado en 2003

Prognostic and predictive biomarkers in early stage NSCLC: CTCs and serum/plasma markers

artículo científico publicado en 2013

Progress and prospects of early detection in lung cancer

artículo científico publicado en 2017

Protein Z: A putative novel biomarker for early detection of ovarian cancer

artículo científico publicado en 2016

Protein kinase C delta is phosphorylated on five novel Ser/Thr sites following inducible overexpression in human colorectal cancer cells

artículo científico publicado en 2007

Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

scientific article published on 03 June 2020

Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

artículo científico publicado en 2019

Qualification of M30 and M65 ELISAs as surrogate biomarkers of cell death: long term antigen stability in cancer patient plasma

article by J. Cummings et al published 27 February 2007 in Cancer Chemotherapy and Pharmacology

Quantification of skeletal metastases in castrate-resistant prostate cancer predicts progression-free and overall survival

artículo científico publicado en 2014

Quantitative mass spectrometry-based techniques for clinical use: biomarker identification and quantification

artículo científico publicado en 2008

Quantitative multiplexed quantum dot immunohistochemistry.

artículo científico publicado en 2008

Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.

artículo científico publicado en 2009

Recent advances in targeting regulators of apoptosis in cancer cells for therapeutic gain

artículo científico publicado en 2006

Recent advances in understanding apoptosis: new therapeutic opportunities in cancer chemotherapy

artículo científico publicado en 2003

Reciprocal relationship between expression of hypoxia inducible factor 1alpha (HIF-1alpha) and the pro-apoptotic protein bid in ex vivo colorectal cancer

artículo científico publicado en 2008

Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium

artículo científico publicado en 1996

Role of mitochondrial membrane permeabilization in apoptosis and cancer

artículo científico publicado en 2004

Short duration immunochemotherapy followed by radioimmunotherapy consolidation is effective and well tolerated in relapsed follicular lymphoma: 5-year results from a UK National Cancer Research Institute Lymphoma Group study.

artículo científico

Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

artículo científico publicado en 2016

SnapShot: Circulating Tumor Cells

SnapShot: Circulating Tumor Cells

Somatically mutated ABL1 is an actionable and essential NSCLC survival gene

artículo científico publicado en 2016

Specific demonstration of drug-induced tumour cell apoptosis in human xenografts models using a plasma biomarker

artículo científico publicado en 2009

Spotlight on circulating tumour cells

artículo científico publicado en 2017

Src family kinase inhibitor Saracatinib (AZD0530) impairs oxaliplatin uptake in colorectal cancer cells and blocks organic cation transporters

artículo científico publicado en 2010

Statistical considerations of optimal study design for human plasma proteomics and biomarker discovery

artículo científico publicado en 2012

Suppression of apoptosis by v-ABL protein tyrosine kinase is associated with nuclear translocation and activation of protein kinase C in an interleukin-3-dependent haemopoietic cell line ⬇️

artículo científico publicado el 1 de julio de 1995

Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin

artículo científico publicado en 1994

Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response

artículo científico publicado en 2013

Synchronous apoptosis in established tumors leads to the induction of adaptive immunity

artículo científico publicado en 2013

Systematic analysis of circulating soluble angiogenesis-associated proteins in ICON7 identifies Tie2 as a biomarker of vascular progression on bevacizumab ⬇️

artículo científico publicado en 2016

Targeting DNA damage in SCLC.

artículo científico publicado en 2017

Tetracycline regulated systems in functional oncogenomics ⬇️

artículo científico publicado el 28 de marzo de 2007

The clinical utility of circulating tumour cells in patients with small cell lung cancer

artículo científico publicado en 2017

The combination of circulating Ang1 and Tie2 levels predicts progression-free survival advantage in bevacizumab-treated patients with ovarian cancer

artículo científico publicado en 2014

The development of composite circulating biomarker models for use in anticancer drug clinical development

artículo científico publicado en 2011

The interaction between prognostic and pharmacodynamic biomarkers.

artículo científico publicado en 2013

The non-genotoxic hepatocarcinogen nafenopin suppresses rodent hepatocyte apoptosis induced by TGFbeta1, DNA damage and Fas.

artículo científico publicado en 1998

The novel Bcl-2 inhibitor ABT-737 is more effective in hypoxia and is able to reverse hypoxia-induced drug resistance in neuroblastoma cells

artículo científico publicado en 2011

The rodent non-genotoxic hepatocarcinogen nafenopin suppresses apoptosis preferentially in non-cycling hepatocytes but also elevates CDK4, a cell cycle progression factor

artículo científico publicado en 1998

The suppression of drug-induced apoptosis by activation of v-ABL protein tyrosine kinase

artículo científico publicado en 1994

Tracking genomic cancer evolution for precision medicine: the lung TRACERx study

artículo científico publicado en 2014

Tracking the Evolution of Non-Small-Cell Lung Cancer

artículo científico publicado en 2017

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer.

artículo científico publicado en 2014

Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study.

artículo científico publicado en 2016

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study

artículo científico publicado en 2019

Validation of an ELISA for the determination of rituximab pharmacokinetics in clinical trials subjects

artículo científico publicado en 2010

Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP.

artículo científico publicado en 2005

Vasculogenic mimicry in small cell lung cancer

artículo científico publicado en 2016

X-linked inhibitor of apoptosis protein as a therapeutic target

artículo científico publicado en 2007

[18F]-FLT positron emission tomography can be used to image the response of sensitive tumors to PI3-kinase inhibition with the novel agent GDC-0941.

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