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Lista de obras de Peter Vandenabeele

18th Euroconference on Apoptosis in Ghent, Belgium, 1-4 September 2010.

artículo científico publicado en 2011

6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury

artículo científico publicado en 2017

A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand

artículo científico publicado en 2003

A T cell clone which responds to interkeukin 2 but not to interleukin 4

scholarly article by Werner Müller & Peter Vandenabeele published 1987 in European Journal of Immunology

A caspase-activated factor (CAF) induces mitochondrial membrane depolarization and cytochrome c release by a nonproteolytic mechanism.

artículo científico publicado en 1998

A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

artículo científico publicado en 2014

A novel caspase-2 complex containing TRAF2 and RIP1.

artículo científico publicado en 2004

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

artículo científico publicado en 2012

A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins.

artículo científico publicado en 2007

A real-time fluorometric method for the simultaneous detection of cell death type and rate

artículo científico publicado en 2016

A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress.

artículo científico publicado en 2016

A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins

artículo científico publicado en 1997

A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

artículo científico publicado en 2019

ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages

artículo científico publicado en 2012

Activated caspase-1 is not a central mediator of inflammation in the course of ischemia-reperfusion.

artículo científico publicado en 2001

Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes

Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2

artículo científico publicado en 2007

Alice in caspase land. A phylogenetic analysis of caspases from worm to man

artículo científico publicado en 2002

Alternatively activated macrophages and impaired phagocytosis of S. aureus in chronic rhinosinusitis

artículo científico publicado en 2010

An evolutionary perspective on the necroptotic pathway

artículo científico publicado en 2016

An inactivating caspase-11 passenger mutation muddles sepsis research

artículo científico publicado en 2013

An outline of necrosome triggers

artículo científico publicado en 2016

Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor

artículo científico publicado en 2021

Antioxidant potential of CORM-A1 and resveratrol during TNF-α/cycloheximide-induced oxidative stress and apoptosis in murine intestinal epithelial MODE-K cells

artículo científico publicado en 2015

Apoptosis and necrosis: detection, discrimination and phagocytosis

artículo científico publicado en 2008

Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1.

artículo científico publicado en 2005

Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis

artículo científico publicado en 2018

Apoptotic and necrotic cell death induced by death domain receptors.

artículo científico publicado en 2001

Are metacaspases caspases?

artículo científico publicado en 2007

Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity

artículo científico publicado en 1998

Author Correction: Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin

artículo científico publicado en 2018

Autophagy: for better or for worse

artículo científico

BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton

artículo científico

Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death

artículo científico publicado en 2004

Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex

scientific article published on 26 May 2020

Beclin1: a role in membrane dynamics and beyond

artículo científico publicado en 2012

Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock

artículo científico publicado en 2019

Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo

artículo científico publicado en 2016

Butylated hydroxyanisole is more than a reactive oxygen species scavenger

artículo científico publicado en 2006

CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3.

artículo científico publicado en 2016

Calcium and connexin-based intercellular communication, a deadly catch?

scientific article published on 31 May 2011

Caspase deficiency alters the murine gut microbiome

artículo científico publicado en 2011

Caspase inhibitors promote alternative cell death pathways

artículo científico publicado en 2006

Caspase substrates: easily caught in deep waters?

artículo científico publicado en 2009

Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity

artículo científico publicado en 2004

Caspase-1 and caspase-8 cleave and inactivate cellular parkin

scientific article published on 11 April 2003

Caspase-12: an overview

artículo científico publicado en 2004

Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies.

artículo científico publicado en 2003

Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin

artículo científico publicado en 2011

Caspase-14 overexpression in hairless mice is not involved in utricle formation

artículo científico publicado en 2013

Caspase-14 protects against epidermal UVB photodamage and water loss

artículo científico publicado en 2007

Caspase-14 reveals its secrets

artículo científico publicado en 2008

Caspase-14-deficient mice are more prone to the development of parakeratosis

artículo científico publicado en 2012

Caspase-3 and RasGAP: a stress-sensing survival/demise switch.

artículo científico publicado en 2013

Caspase-3 probes for PET imaging of apoptotic tumor response to anticancer therapy

scientific article published on 01 May 2019

Caspase-7 in molar tooth development.

artículo científico publicado en 2012

Caspase-7 participates in differentiation of cells forming dental hard tissues

artículo científico publicado en 2013

Caspase-containing complexes in the regulation of cell death and inflammation

artículo científico publicado en 2006

Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

artículo científico publicado en 2010

Caspase-mediated cleavage of the U snRNP-associated Sm-F protein during apoptosis.

artículo científico publicado en 2003

Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis

artículo científico publicado en 2007

Caspases in cell survival, proliferation and differentiation.

artículo científico publicado en 2006

Caspases leave the beaten track: caspase-mediated activation of NF-kappaB.

artículo científico publicado en 2006

Cathepsin B-mediated activation of the proinflammatory caspase-11.

artículo científico publicado en 1998

Cell death in the skin

artículo científico publicado en 2009

Cell death induction by receptors of the TNF family: towards a molecular understanding.

artículo científico publicado en 1997

Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells

artículo científico publicado en 2012

Characteristic ERK1/2 signaling dynamics distinguishes necroptosis from apoptosis

artículo científico publicado en 2021

Characterization of seven murine caspase family members

artículo científico publicado en 1997

Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

scientific article published on 25 May 2020

Cigarette smoke and the terminal ileum: increased autophagy in murine follicle-associated epithelium and Peyer's patches

artículo científico publicado en 2011

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

artículo científico publicado en 2015

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

artículo científico publicado en 2005

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

artículo científico publicado en 2009

Clearance of apoptotic and necrotic cells and its immunological consequences

artículo científico publicado en 2006

Clearance of dead cells: mechanisms, immune responses and implication in the development of diseases

artículo científico publicado en 2010

Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor

artículo científico publicado en 1997

Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis

artículo científico publicado en 1999

Comparative study of the differential cell death protecting effect of various ROS scavengers

artículo científico publicado en 2019

Connexin-related signaling in cell death: to live or let die?

artículo científico publicado en 2009

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Consensus guidelines for the detection of immunogenic cell death

artículo científico publicado en 2014

Correction: A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

artículo científico publicado en 2020

Correction: Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal

artículo científico publicado en 2018

Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist

artículo científico publicado en 2008

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

scientific journal article

Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF ⬇️

artículo científico publicado el 1 de julio de 1995

DAMPs activating innate and adaptive immune responses in COPD.

artículo científico

DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown ⬇️

artículo científico publicado el 24 de enero de 2011

Death penalty for keratinocytes: apoptosis versus cornification.

artículo científico publicado en 2005

Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.

artículo científico publicado en 2001

Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions

artículo científico publicado en 2014

Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike

artículo científico publicado en 2012

Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain

artículo científico publicado en 2010

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

artículo científico publicado en 2014

Determination of apoptotic and necrotic cell death in vitro and in vivo.

artículo científico publicado en 2013

Development of a dedicated peptide tandem mass spectral library for conservation science

artículo científico publicado en 2012

Development of a simple, sensitive and specific bioassay for interleukin-1 based on the proliferation of RPMI 1788 cells. Comparison with other bioassays for IL-1.

artículo científico publicado en 1990

Different pathways mediate cytochrome c release after photodynamic therapy with hypericin

artículo científico publicado en 2001

Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly

artículo científico publicado en 2002

Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal

scientific journal article

Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma.

artículo científico publicado en 1997

Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.

artículo científico publicado en 2003

Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy

article

Discrimination of zeolites and beryllium containing silicates using portable Raman spectroscometric equipment with near-infrared excitation.

artículo científico publicado en 2011

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

artículo científico publicado en 2002

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

artículo científico publicado en 2021

Distinct mechanisms are involved in tumoristatic and tumoricidal activities of monocyte-derived dendritic cells

artículo científico publicado en 2004

Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes

artículo científico publicado en 2003

Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: identification of two cleavage sites by microsequencing

artículo científico publicado en 2004

Dual face apoptotic machinery: from initiator of apoptosis to guardian of necroptosis

artículo científico publicado en 2011

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

artículo científico publicado en 2011

ER stress-induced inflammation: does it aid or impede disease progression?

artículo científico publicado en 2012

Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation

artículo científico publicado en 2016

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

artículo científico publicado en 2011

Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation.

artículo científico publicado en 2001

Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

artículo científico publicado en 2015

Enzymatic degradation of tumor necrosis factor by activated human neutrophils: role of elastase

artículo científico publicado en 1991

Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing

artículo científico publicado en 2000

Erratum

scholarly article published in Autophagy

Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke

artículo científico publicado en 2012

Escherichia coli induces bovine neutrophil cell death independent from caspase-3/-7/-1, but with phosphatidylserine exposure prior to membrane rupture

artículo científico publicado en 2013

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

artículo científico publicado en 2014

Evidence that pentoxifylline reduces anti-CD3 monoclonal antibody-induced cytokine release syndrome

artículo científico publicado en 1991

Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis

artículo científico publicado en 2020

Expression of calcium-sensing receptor in quail granulosa explants: a key to survival during folliculogenesis

artículo científico publicado en 2010

Extracellular ATP and P₂X₇ receptor exert context-specific immunogenic effects after immunogenic cancer cell death.

artículo científico publicado en 2016

Filaggrin Degradation by Caspase-14 Is Required for UVB Photoprotection but Does Not Influence Allergic Sensitization in a Mouse Model of Atopic Dermatitis

artículo científico publicado en 2012

Fine-tuning nucleophosmin in macrophage differentiation and activation.

artículo científico publicado en 2011

Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma ⬇️

artículo científico publicado el 1 de octubre de 1992

Functional protection by acute phase proteins alpha(1)-acid glycoprotein and alpha(1)-antitrypsin against ischemia/reperfusion injury by preventing apoptosis and inflammation

scientific article published on 01 September 2000

Gene cloning and structure - function relationship of cytokines such as TNF and interleukins

article

Generation and Biological Characterization of Membrane-bound, Uncleavable Murine Tumor Necrosis Factor ⬇️

artículo científico publicado el 4 de agosto de 1995

Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells

artículo científico publicado en 2016

Generation of dendritic cells from bone marrow progenitors using GM-CSF, TNF-alpha, and additional cytokines: antagonistic effects of IL-4 and IFN-gamma and selective involvement of TNF-alpha receptor-1

scientific article published on 01 August 1997

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

scientific article published on 25 June 2018

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

artículo científico publicado en 2015

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

artículo científico publicado en 2009

Gut microbiota affects sensitivity to acute DSS-induced colitis independently of host genotype

artículo científico publicado en 2013

Head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells

artículo científico publicado en 2002

Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model

artículo científico publicado en 2017

Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design

artículo científico publicado en 2016

How do we fit ferroptosis in the family of regulated cell death?

artículo científico publicado en 2017

Human TNF mutants with selective activity on the p55 receptor.

artículo científico publicado en 1993

Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor

artículo científico publicado en 1994

Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.

artículo científico publicado en 2010

Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin ⬇️

artículo científico publicado el 23 de diciembre de 2011

Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis

scientific article published on 01 November 1998

IL-4 acts synergistically on the IL-2 response of an autoreactive T-cell clone; synergism correlates with increased intracellular IL-2, but not with a modified IL-2 receptor expression

artículo científico publicado en 1990

INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation

artículo científico publicado en 2004

IP3, a small molecule with a powerful message

artículo científico

Identification of a new caspase homologue: caspase-14

artículo científico publicado en 1998

Identification of caspases that cleave presenilin-1 and presenilin-2

artículo científico publicado en 1999

Identification of protein binders in works of art by high-performance liquid chromatography-diode array detector analysis of their tryptic digests.

artículo científico publicado en 2009

Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants.

artículo científico publicado en 2001

Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection

artículo científico publicado en 2020

Immunogenic Apoptotic Cell Death and Anticancer Immunity

artículo científico publicado en 2016

Immunogenic cell death and DAMPs in cancer therapy

artículo científico publicado en 2012

Immunogenic cell death, DAMPs and anticancer therapeutics: an emerging amalgamation

artículo científico publicado en 2009

Impact of caspase-1/11, -3, -7, or IL-1β/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.

artículo científico publicado en 2017

Impairment of phagocytosis of apoptotic cells and its role in chronic airway diseases

scientific article published on September 2010

In vivo imaging of NF-kappaB activity during Escherichia coli-induced mammary gland infection

artículo científico publicado en 2008

In vivo immunosuppression induced by a weakly mitogenic antibody to mouse CD3: evidence that induction of long-lasting in vivo unresponsiveness requires TcR signaling

artículo científico publicado en 1994

Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors

artículo científico publicado en 2005

Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice

artículo científico publicado en 2013

Inflammatory caspases: targets for novel therapies

artículo científico publicado en 2007

Inflammatory mediators in Escherichia coli-induced mastitis in mice

artículo científico publicado en 2008

Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation

artículo científico publicado en 1999

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

artículo científico publicado en 1998

Inhibition of nuclear factor-kappaB by a nitro-derivative of flurbiprofen: a possible mechanism for antiinflammatory and antiproliferative effect

artículo científico publicado en 2003

Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity

artículo científico publicado en 2003

Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt.

artículo científico publicado en 2009

Initiation and execution mechanisms of necroptosis: an overview

artículo científico publicado en 2017

Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1).

artículo científico publicado en 2003

Interaction patches of procaspase-1 caspase recruitment domains (CARDs) are differently involved in procaspase-1 activation and receptor-interacting protein 2 (RIP2)-dependent nuclear factor κB signaling

artículo científico publicado en 2011

Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome

artículo científico publicado en 2012

Interleukin-10 controls interferon-gamma and tumor necrosis factor production during experimental endotoxemia

artículo científico publicado en 1994

Intermediate domain of receptor-interacting protein kinase 1 (RIPK1) determines switch between necroptosis and RIPK1 kinase-dependent apoptosis.

artículo científico publicado en 2012

Intersections between Regulated Cell Death and Autophagy

artículo científico publicado en 2019

Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death

artículo científico publicado en 2020

Is SIRT2 required for necroptosis?

artículo científico publicado en 2014

Is amyloidogenesis during Alzheimer's disease due to an IL-1-/IL-6-mediated 'acute phase response' in the brain?

artículo científico publicado en 1991

Keratinocyte Expression of A20/TNFAIP3 Controls Skin Inflammation Associated with Atopic Dermatitis and Psoriasis

artículo científico publicado en 2018

Keratinocyte-specific ablation of RIPK4 allows epidermal cornification but impairs skin barrier formation

artículo científico publicado en 2018

Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis

artículo científico publicado en 2011

Life and death of female gametes during oogenesis and folliculogenesis

scientific article published on 14 July 2008

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

artículo científico publicado en 2012

MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis

artículo científico publicado en 2011

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

artículo científico publicado en 2017

MLKL Reveals Its Friendly Face: A Role in Nerve Regeneration

scientific article published on 01 November 2018

MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.

artículo científico publicado en 2014

MLKL deficiency in Braf<sup>V600E</sup>Pten<sup>-/-</sup> melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice

scientific article published on 14 April 2022

Macrophages regulate the clearance of living cells by calreticulin

artículo científico publicado en 2018

Major cell death pathways at a glance

artículo científico publicado en 2009

Many faces of DAMPs in cancer therapy

artículo científico publicado en 2013

Many stimuli pull the necrotic trigger, an overview

artículo científico publicado en 2012

Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy

artículo científico publicado en 2003

Methods for distinguishing apoptotic from necrotic cells and measuring their clearance

artículo científico publicado en 2008

Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) production during murine endotoxaemia

artículo científico publicado en 1996

Mitochondria and NADPH oxidases are the major sources of TNF-α/cycloheximide-induced oxidative stress in murine intestinal epithelial MODE-K cells

artículo científico publicado en 2015

Mitochondrial intermembrane proteins in cell death

artículo científico publicado en 2003

Mitotic catastrophe as a prestage to necrosis in mouse liver cells treated with Helicobacter pullorum sonicates

artículo científico publicado en 2009

Modulation by caspases of tumor necrosis factor-stimulated c-Jun N-terminal kinase activation but not nuclear factor-kappaB signaling

artículo científico publicado en 2003

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

artículo científico publicado en 2015

Molecular crosstalk between apoptosis, necroptosis, and survival signaling

artículo científico publicado en 2015

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

artículo científico publicado en 2012

Molecular mechanisms and pathophysiology of necrotic cell death

artículo científico publicado en 2008

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

Mouse mammary gland involution is associated with cytochrome c release and caspase activation

artículo científico publicado en 2001

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis.

artículo científico publicado en 2018

NADPH oxidases: new players in TNF-induced necrotic cell death

artículo científico publicado en 2007

NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling.

artículo científico publicado en 2015

NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis

artículo científico publicado en 2015

NLRP3/caspase-1-independent IL-1beta production mediates diesel exhaust particle-induced pulmonary inflammation

artículo científico publicado en 2011

NOD-like receptors and the innate immune system: coping with danger, damage and death.

artículo científico

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

scholarly article by Behrouz Hassannia et al published 1 August 2018 in Journal of Clinical Investigation

Nanoscopic X-ray fluorescence imaging and quantification of intracellular key-elements in cryofrozen Friedreich's ataxia fibroblasts

artículo científico publicado en 2018

NecroX-7 reduces necrotic core formation in atherosclerotic plaques of Apoe knockout mice

artículo científico publicado en 2016

Necroptosis and its role in inflammation

artículo científico publicado en 2015

Necroptosis, in vivo detection in experimental disease models

artículo científico publicado en 2014

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.

artículo científico publicado en 2009

Necroptosis: (Last) Message in a Bubble

artículo científico publicado en 2017

Necroptosis: A Novel Cell Death Modality and Its Potential Relevance for Critical Care Medicine.

artículo científico publicado en 2016

Necroptosis: the release of damage-associated molecular patterns and its physiological relevance

artículo científico publicado en 2013

Necroptotic cell death in anti-cancer therapy

artículo científico publicado en 2017

Necrosis is associated with IL-6 production but apoptosis is not.

artículo científico publicado en 2005

Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response

artículo científico publicado en 2006

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

artículo científico publicado en 2012

Necrostatin-1 blocks both RIPK1 and IDO: consequences for the study of cell death in experimental disease models

artículo científico publicado en 2012

Necrotic cell death and 'necrostatins': now we can control cellular explosion

artículo científico publicado en 2008

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

artículo científico publicado en 2010

Non-apoptotic functions of caspase-7 during osteogenesis

artículo científico publicado en 2014

Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue

artículo científico publicado en 2015

Non-classical proIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent

artículo científico publicado en 2014

Non-specific effects of methyl ketone peptide inhibitors of caspases

artículo científico publicado en 1999

Noninvasive whole-body imaging of phosphatidylethanolamine as a cell death marker using 99mTc-duramycin during TNF-induced SIRS.

artículo científico publicado en 2018

Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties

artículo científico publicado en 2015

Novel Reporter for Faithful Monitoring of ERK2 Dynamics in Living Cells and Model Organisms

artículo científico publicado en 2015

Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis

artículo científico publicado en 2018

P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death

artículo científico publicado en 1999

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

article by Thirumala-Devi Kanneganti et al published April 2007 in Immunity

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

artículo científico publicado en 2015

Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production

artículo científico publicado en 2003

Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential.

artículo científico publicado en 2000

Programmed necrosis from molecules to health and disease

scientific article published on January 2011

Protein synthesis persists during necrotic cell death

artículo científico publicado en 2005

Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response.

artículo científico publicado en 2012

Proteolysis of enteric cell villin by Entamoeba histolytica cysteine proteinases

artículo científico publicado en 2003

Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis

artículo científico publicado en 1999

Proteome-wide Identification of HtrA2/Omi Substrates

artículo científico publicado en 2007

Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity

scientific journal article

RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

artículo científico publicado en 2011

RIP kinases at the crossroads of cell death and survival

artículo científico publicado en 2009

RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis

artículo científico publicado en 2012

RIP1's function in NF-kappaB activation: from master actor to onlooker.

artículo científico publicado en 2010

RIP1, a kinase on the crossroads of a cell's decision to live or die

artículo científico publicado en 2007

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

artículo científico publicado en 2014

RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions.

artículo científico publicado en 2014

RIPK1 protects from TNF-α-mediated liver damage during hepatitis

artículo científico publicado en 2016

RIPK1 protects hepatocytes from Kupffer cells-mediated TNF-induced apoptosis in mouse models of PAMP-induced hepatitis.

artículo científico publicado en 2017

RIPK1 protects hepatocytes from death in Fas-induced hepatitis

artículo científico publicado en 2017

RIPK1-dependent cell death: a novel target of the Aurora kinase inhibitor Tozasertib (VX-680).

artículo científico publicado en 2018

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

artículo científico publicado en 2013

RIPK4 activity in keratinocytes is controlled by the SCFβ-TrCP ubiquitin ligase to maintain cortical actin organization.

artículo científico publicado en 2018

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

artículo científico publicado en 2013

Recombinant interleukin 2 induces immunoglobulin secretion in Staphylococcus aureus Cowan strain I activated human B-cells

artículo científico publicado en 1985

Reconstitution of protection against Aspergillus infection in chronic granulomatous disease (CGD)

artículo científico publicado en 2009

Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies

artículo científico publicado en 2022

Regulated necrosis: disease relevance and therapeutic opportunities

artículo científico publicado en 2016

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

artículo científico publicado en 2014

Regulation of RIPK1's cell death function by phosphorylation

artículo científico publicado en 2015

Regulation of the expression and processing of caspase-12

artículo científico publicado en 2003

Requirement for tumor necrosis factor-receptor 2 in alveolar chemokine expression depends upon the form of the ligand

artículo científico publicado en 2005

Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal

artículo científico publicado en 2015

Role of IL-1α and the Nlrp3/caspase-1/IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD.

artículo científico publicado en 2011

Selective stimulation of either tumor necrosis factor receptor differentially induces pain behavior in vivo and ectopic activity in sensory neurons in vitro

artículo científico publicado en 2008

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

scientific article published on 15 April 2019

Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide

artículo científico

Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways

artículo científico publicado en 2011

Shining light on cell death processes - a novel biosensor for necroptosis, a newly described cell death program

artículo científico

Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis

artículo científico publicado en 2017

Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas.

artículo científico publicado en 2002

Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock

artículo científico publicado en 2014

Simultaneous targeting of interleukin-1 and interleukin-18 is required for protection against inflammatory and septic shock

SitePredicting the cleavage of proteinase substrates

artículo científico publicado en 2009

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

artículo científico publicado en 2011

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.

artículo científico publicado en 2017

Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle

artículo científico publicado en 2001

Structure/Function analysis of p55 tumor necrosis factor receptor and fas-associated death domain. Effect on necrosis in L929sA cells.

artículo científico publicado en 2000

Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases.

artículo científico publicado en 2009

Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB

scholarly article by Louise V Webb et al published 19 February 2019 in Immunity

Synchronized renal tubular cell death involves ferroptosis. ⬇️

artículo científico publicado en 2014

TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation

artículo científico publicado en 2011

TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones.

artículo científico publicado en 2002

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

scientific journal article

TNF/TNF-R1 pathway is involved in doxorubicin-induced acute sterile inflammation

artículo científico publicado en 2013

TNFR1- and TNFR2-mediated signaling pathways in human kidney are cell type-specific and differentially contribute to renal injury

artículo científico publicado en 2005

TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation.

artículo científico publicado en 2012

TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation

artículo científico publicado en 2000

Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes

artículo científico publicado en 2008

Targeting Ferroptosis to Iron Out Cancer

artículo científico publicado en 2019

Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1-mediated maturation and release of interleukin-1beta

artículo científico publicado en 2004

Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death

artículo científico publicado en 2014

Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation

artículo científico publicado en 2000

The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin

scientific article published in Journal of Biological Chemistry

The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component

artículo científico publicado en 2001

The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.

artículo científico publicado en 2017

The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation

artículo científico publicado en 2007

The Pseudomonas aeruginosa type III secretion system has an exotoxin S/T/Y independent pathogenic role during acute lung infection

artículo científico publicado en 2012

The Ripoptosome: death decision in the cytosol

artículo científico publicado en 2011

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

scientific article published on 31 July 2018

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

artículo científico publicado en 2016

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

artículo científico publicado en 2016

The adjuvant-like activity of staphylococcal enterotoxin B in a murine asthma model is independent of IL-1R signaling

artículo científico publicado en 2013

The death-fold superfamily of homotypic interaction motifs

artículo científico

The emergence of phox-ER stress induced immunogenic apoptosis ⬇️

artículo científico publicado el 1 de agosto de 2012

The emerging roles of serine protease cascades in the epidermis

artículo científico publicado en 2009

The endothelial monocyte-activating polypeptide II (EMAP II) is a substrate for caspase-7.

artículo científico publicado en 2000

The flick of a switch: which death program to choose?

artículo científico publicado en 2012

The gamma subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3.

artículo científico publicado en 2001

The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses

artículo científico publicado en 2020

The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawal

artículo científico publicado en 2010

The mitochondrial serine protease HtrA2/Omi: an overview

artículo científico publicado en 2008

The molecular machinery of regulated cell death

scientific article published on 04 April 2019

The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail.

artículo científico publicado en 2002

The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis

artículo científico publicado en 2016

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

artículo científico publicado en 2002

The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling

artículo científico publicado en 2012

The role of the kinases RIP1 and RIP3 in TNF-induced necrosis

artículo científico publicado en 2010

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

artículo científico publicado en 2002

The skin microbiome of caspase-14-deficient mice shows mild dysbiosis.

artículo científico publicado en 2014

The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems

artículo científico publicado en 2013

The somatostatin analogue TT-232 induces apoptosis in A431 cells: sustained activation of stress-activated kinases and inhibition of signalling to extracellular signal-regulated kinases.

artículo científico publicado en 2001

The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF

artículo científico publicado en 2019

Therapeutic Targeting of Connexin Channels: New Views and Challenges

artículo científico publicado en 2018

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

artículo científico publicado en 2002

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps

artículo científico publicado en 2019

Tortoiseshell or Polymer? Spectroscopic Analysis to Redefine a Purported Tortoiseshell Box with Gold Decorations as a Plastic Box with Brass

artículo científico publicado en 2016

Towards the differentiation of non-treated and treated corundum minerals by ion-beam-induced luminescence and other complementary techniques

artículo científico publicado en 2009

Toxic proteins released from mitochondria in cell death

artículo científico publicado en 2004

Tozasertib Analogues as Inhibitors of Necroptotic Cell Death

artículo científico publicado en 2018

Transfer of IP₃ through gap junctions is critical, but not sufficient, for the spread of apoptosis

artículo científico publicado en 2011

Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation

artículo científico publicado en 2001

Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death ⬇️

artículo científico publicado en 2008

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

artículo científico publicado en 2018

Tryptic peptide analysis of protein binders in works of art by liquid chromatography-tandem mass spectrometry

artículo científico publicado en 2009

Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage.

artículo científico publicado en 1999

Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma

artículo científico publicado en 2016

Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: role in the Ca2+ sensitization of myosin light chain20 phosphorylation

artículo científico publicado en 2003

Tumor necrosis factor-induced cytotoxicity is not related to rates of mitochondrial morphological abnormalities or autophagy-changes that can be mediated by TNFR-I or TNFR-II.

artículo científico publicado en 1998

Tumor necrosis factor-mediated cell death: to break or to burst, that's the question

artículo científico publicado en 2010

Tumoricidal activity of monocyte-derived dendritic cells: evidence for a caspase-8-dependent, Fas-associated death domain-independent mechanism.

artículo científico publicado en 2001

Tumour necrosis factor-induced activation of c-Jun N-terminal kinase is sensitive to caspase-dependent modulation while activation of mitogen-activated protein kinase (MAPK) or p38 MAPK is not.

artículo científico publicado en 2002

Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.

artículo científico publicado en 1997

Two tumour necrosis factor receptors: structure and function.

artículo científico publicado en 1995

Type II tumour necrosis factor-alpha receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways.

artículo científico publicado en 2001

USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability

artículo científico publicado en 2016

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.

artículo científico publicado en 2018

Ultraviolet B radiation-induced apoptosis in human keratinocytes: cytosolic activation of procaspase-8 and the role of Bcl-2.

artículo científico publicado en 2003

Use of dendrograms of slice spectra as a new graphical tool for the interpretation of two-dimensional correlation spectra

artículo científico publicado en 2009

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

artículo científico publicado en 2016

Vitamin D3 induces caspase-14 expression in psoriatic lesions and enhances caspase-14 processing in organotypic skin cultures

artículo científico publicado en 2004

When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157.

artículo científico publicado en 2017

Workshop summary: cell death mechanisms controlled by the TNF family

artículo científico publicado en 2011

Yersinia enterocolitica YopP-induced apoptosis of macrophages involves the apoptotic signaling cascade upstream of bid.

artículo científico publicado en 2001

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

scientific journal article

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

artículo científico publicado en 2011

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

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