Lista de obras - Gerold Schmitt-Ulms - Dominio Público Uruguay

A Proteome Resource of Ovarian Cancer Ascites: Integrated Proteomic and Bioinformatic Analyses To Identify Putative Biomarkers

A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition

artículo científico publicado en 2017

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

artículo científico publicado en 2015

APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes

scientific article published on 15 April 2009

Alzheimer disease: advances in pathogenesis, diagnosis, and therapy

artículo científico publicado en 2011

Alzheimer's disease: Selectively tuning gamma-secretase

artículo científico publicado en 2010

An emerging role of the cellular prion protein as a modulator of a morphogenetic program underlying epithelial-to-mesenchymal transition

artículo científico publicado en 2014

An endogenous PI3K interactome promoting astrocyte mediated neuroprotection identifies a novel association with RNA binding protein ZC3H14

artículo científico publicado en 2020

An updated h-index measures both the primary and total scientific output of a researcher

artículo científico publicado en 2015

Application of CRISPR genetic screens to investigate neurological diseases.

artículo científico publicado en 2019

Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice

artículo científico publicado en 2021

Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death

scientific article published on 02 December 2019

Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes

artículo científico publicado en 2004

CRISPR-Cas9 System: Opportunities and Concerns

artículo científico publicado en 2016

CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

artículo científico publicado en 2014

Childhood Onset in Familial Prion Disease With a Novel Mutation in the PRNP Gene

article

Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90.

artículo científico publicado en 2011

Co-immunoprecipitations revisited: an update on experimental concepts and their implementation for sensitive interactome investigations of endogenous proteins

artículo científico publicado en 2007

Combining molecular dynamics simulations and experimental analyses in protein misfolding

scientific article published on 01 January 2019

Correction: Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones.

artículo científico publicado en 2009

Crosslinking Strategies for the Study of Membrane Protein Complexes and Protein Interaction Interfaces ⬇️

artículo científico publicado el 1 de enero de 2006

Does BDNF Val66Met contribute to preclinical Alzheimer's disease?

artículo científico publicado en 2016

Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrPSc Accumulation ⬇️

artículo científico publicado el 17 de noviembre de 2011

Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining

artículo científico publicado en 2016

Endoproteolytic processing of the mammalian prion glycoprotein family

artículo científico publicado en 2013

Engineering a murine cell line for the stable propagation of hamster prions

artículo científico publicado en 2019

Evidence for retrogene origins of the prion gene family

artículo científico publicado en 2011

Evolutionary descent of prion genes from the ZIP family of metal ion transporters

artículo científico publicado en 2009

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.

artículo científico publicado en 2018

Family reunion--the ZIP/prion gene family

artículo científico publicado en 2010

Functional Amyloids and their Possible Influence on Alzheimer Disease

scientific article published on 16 October 2017

Interactions of MAP/microtubule affinity regulating kinases with the adaptor complex AP-2 of clathrin-coated vesicles

artículo científico publicado en 2009

Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

artículo científico publicado en 2009

Interactome analyses of mature γ-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2.

artículo científico publicado en 2013

Interactome and interface protocol (2IP): a novel strategy for high sensitivity topology mapping of protein complexes

artículo científico publicado en 2007

LIV-1 ZIP ectodomain shedding in prion-infected mice resembles cellular response to transition metal starvation

artículo científico publicado en 2012

Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography

artículo científico publicado en 2003

Method for the affinity purification of covalently linked peptides following cyanogen bromide cleavage of proteins

artículo científico publicado en 2009

NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?

artículo científico publicado en 2016

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

artículo científico publicado en 2015

Overcoming barriers and thresholds – signaling of oligomeric Aβ through the prion protein to Fyn ⬇️

artículo científico publicado el 16 de julio de 2013

Peptide separations by on-line MudPIT compared to isoelectric focusing in an off-gel format: application to a membrane-enriched fraction from C2C12 mouse skeletal muscle cells.

artículo científico publicado en 2009

Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue

artículo científico publicado en 2016

Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression

artículo científico publicado en 2018

PrionHome: a database of prions and other sequences relevant to prion phenomena

artículo científico publicado en 2012

Proteome-wide identification of mycobacterial pupylation targets

artículo científico publicado en 2010

Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

artículo científico publicado en 2017

Somatostatin in Alzheimer'S disease: A new Role for an Old Player

artículo científico publicado en 2017

Structural biology of presenilin 1 complexes

artículo científico publicado en 2014

Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes

artículo científico publicado en 2013

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

artículo científico publicado en 2006

TMP21 transmembrane domain regulates gamma-secretase cleavage

artículo científico publicado en 2009

Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins

scientific article published on 07 November 2019

The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections

artículo científico publicado en 2007

The Evolutionary unZIPping of a Dimerization Motif—A Comparison of ZIP and PrP Architectures.

artículo científico publicado en 2017

The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome

artículo científico publicado en 2015

The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis

artículo científico publicado en 2015

The ZIP-prion connection

artículo científico publicado en 2012

The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer

artículo científico publicado en 2013

The human brain somatostatin interactome: SST binds selectively to P-type family ATPases

artículo científico publicado en 2019

The in vivo brain interactome of the amyloid precursor protein

scientific journal article

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

artículo científico publicado en 2007

The presenilin proteins are components of multiple membrane-bound complexes that have different biological activities

artículo científico publicado en 2004

The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling

artículo científico publicado en 2018

The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6

scientific journal article

Time-Controlled Transcardiac Perfusion Crosslinking for In Vivo Interactome Studies ⬇️

artículo científico publicado el 1 de enero de 2012

Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues

artículo científico publicado en 2004

Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease.

artículo científico publicado en 2017

Vigilin interacts with signal peptide peptidase

artículo científico publicado en 2012

Wild-type Shadoo proteins convert to amyloid-like forms under native conditions.

artículo científico publicado en 2010

Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration.

artículo científico publicado en 2016

Lista de obras de Gerold Schmitt-Ulms

A Proteome Resource of Ovarian Cancer Ascites: Integrated Proteomic and Bioinformatic Analyses To Identify Putative Biomarkers

A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes

Alzheimer disease: advances in pathogenesis, diagnosis, and therapy

Alzheimer's disease: Selectively tuning gamma-secretase

An emerging role of the cellular prion protein as a modulator of a morphogenetic program underlying epithelial-to-mesenchymal transition

An endogenous PI3K interactome promoting astrocyte mediated neuroprotection identifies a novel association with RNA binding protein ZC3H14

An updated h-index measures both the primary and total scientific output of a researcher

Application of CRISPR genetic screens to investigate neurological diseases.

Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice

Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death

Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes

CRISPR-Cas9 System: Opportunities and Concerns

CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

Childhood Onset in Familial Prion Disease With a Novel Mutation in the PRNP Gene

Choice of biological source material supersedes oxidative stress in its influence on DJ-1 in vivo interactions with Hsp90.

Co-immunoprecipitations revisited: an update on experimental concepts and their implementation for sensitive interactome investigations of endogenous proteins

Combining molecular dynamics simulations and experimental analyses in protein misfolding

Correction: Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones.

Crosslinking Strategies for the Study of Membrane Protein Complexes and Protein Interaction Interfaces ⬇️

Does BDNF Val66Met contribute to preclinical Alzheimer's disease?

Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrPSc Accumulation ⬇️

Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining

Endoproteolytic processing of the mammalian prion glycoprotein family

Engineering a murine cell line for the stable propagation of hamster prions

Evidence for retrogene origins of the prion gene family

Evolutionary descent of prion genes from the ZIP family of metal ion transporters

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.

Family reunion--the ZIP/prion gene family

Functional Amyloids and their Possible Influence on Alzheimer Disease

Interactions of MAP/microtubule affinity regulating kinases with the adaptor complex AP-2 of clathrin-coated vesicles

Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

Interactome analyses of mature γ-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2.

Interactome and interface protocol (2IP): a novel strategy for high sensitivity topology mapping of protein complexes

LIV-1 ZIP ectodomain shedding in prion-infected mice resembles cellular response to transition metal starvation

Mass spectrometric analysis of protein mixtures at low levels using cleavable 13C-isotope-coded affinity tag and multidimensional chromatography

Method for the affinity purification of covalently linked peptides following cyanogen bromide cleavage of proteins

NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

Overcoming barriers and thresholds – signaling of oligomeric Aβ through the prion protein to Fyn ⬇️

Peptide separations by on-line MudPIT compared to isoelectric focusing in an off-gel format: application to a membrane-enriched fraction from C2C12 mouse skeletal muscle cells.

Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue

Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression

PrionHome: a database of prions and other sequences relevant to prion phenomena

Proteome-wide identification of mycobacterial pupylation targets

Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

Somatostatin in Alzheimer'S disease: A new Role for an Old Player

Structural biology of presenilin 1 complexes

Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

TMP21 transmembrane domain regulates gamma-secretase cleavage

Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins

The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections

The Evolutionary unZIPping of a Dimerization Motif—A Comparison of ZIP and PrP Architectures.

The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome

The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis

The ZIP-prion connection

The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer

The human brain somatostatin interactome: SST binds selectively to P-type family ATPases

The in vivo brain interactome of the amyloid precursor protein

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

The presenilin proteins are components of multiple membrane-bound complexes that have different biological activities

The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling

The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6

Time-Controlled Transcardiac Perfusion Crosslinking for In Vivo Interactome Studies ⬇️

Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues

Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease.

Vigilin interacts with signal peptide peptidase

Wild-type Shadoo proteins convert to amyloid-like forms under native conditions.

Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration.