Filtros de búsqueda

Lista de obras de Patrizia Agostinis

18th Euroconference on Apoptosis in Ghent, Belgium, 1-4 September 2010.

artículo científico publicado en 2011

5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma

artículo científico publicado en 2011

A Comparative Analysis of the Photosensitized Inhibition of Growth-Factor Regulated Protein Kinases by Hypericin-Derivatives

article

A lipid switch unlocks Parkinson's disease-associated ATP13A2

scientific journal article

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

artículo científico publicado en 2012

A p38(MAPK)/HIF-1 pathway initiated by UVB irradiation is required to induce Noxa and apoptosis of human keratinocytes

artículo científico publicado en 2010

A synthetic peptide substrate specific for casein kinase-1

scientific article published on 01 December 1989

AKT Delays the Early-Activated Apoptotic Pathway in UVB-Irradiated Keratinocytes Via BAD Translocation

artículo científico publicado en 2006

AKT status controls susceptibility of malignant keratinocytes to the early-activated and UVB-induced apoptotic pathway

artículo científico publicado en 2004

ATP13A2/PARK9 regulates endo-/lysosomal cargo sorting and proteostasis through a novel PI(3, 5)P2-mediated scaffolding function.

artículo científico publicado en 2017

ATP13A3 is a major component of the enigmatic mammalian polyamine transport system

artículo científico publicado en 2020

Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes

Acute response of human skin to solar radiation: regulation and function of the p53 protein ⬇️

artículo científico publicado el 1 de octubre de 2001

Adapt, Recycle, and Move on: Proteostasis and Trafficking Mechanisms in Melanoma

artículo científico publicado en 2016

Addicted to secrete - novel concepts and targets in cancer therapy

artículo científico publicado en 2014

An improved orthotopic rat bladder tumor model using Dil-loaded fluorescent AY-27 cells.

artículo científico publicado en 2010

Analysis of the phosphoamino acid content of phosphoproteins

scientific article published on 01 June 1996

Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin

artículo científico publicado en 2015

Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes

article

Assessing autophagy in the context of photodynamic therapy

artículo científico publicado en 2010

Autophagy and mitophagy interplay in melanoma progression

artículo científico

Autophagy and the Kidney: Implications for Ischemia-Reperfusion Injury and Therapy

artículo científico

Autophagy inhibitor chloroquine enhanced the cell death inducing effect of the flavonoid luteolin in metastatic squamous cell carcinoma cells

artículo científico publicado en 2012

Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage

artículo científico publicado en 2010

Autophagy, a major adaptation pathway shaping cancer cell death and anticancer immunity responses following photodynamic therapy

artículo científico publicado en 2015

Autophagy-dependent suppression of cancer immunogenicity and effector mechanisms of innate and adaptive immunity

artículo científico publicado en 2013

Autophagy: a new target or an old strategy for the treatment of Crohn's disease?

artículo científico

Autophagy: for better or for worse

artículo científico

Autophagy: shaping the tumor microenvironment and therapeutic response.

artículo científico

BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton

artículo científico

Bcl-2 family members: essential players in skin cancer.

artículo científico publicado en 2012

Blocking tumor cell eicosanoid synthesis by GP x 4 impedes tumor growth and malignancy

artículo científico publicado en 2006

Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A.

artículo científico publicado en 2013

Cancer immunogenicity, danger signals, and DAMPs: What, when, and how? ⬇️

artículo científico publicado el 31 de julio de 2013

Casein kinase-1 phosphorylates the p75 tumor necrosis factor receptor and negatively regulates tumor necrosis factor signaling for apoptosis

artículo científico publicado en 1995

Casein kinases and their protein substrates in rat liver cytosol: Evidence for their participation in multimolecular systems

article

Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death.

artículo científico publicado en 2016

Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

artículo científico publicado en 2010

Cell death and growth arrest in response to photodynamic therapy with membrane-bound photosensitizers ⬇️

artículo científico publicado el 15 de octubre de 2003

Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses.

artículo científico publicado en 2017

Cell death in the skin

artículo científico publicado en 2009

Cellular photodestruction induced by hypericin in AY-27 rat bladder carcinoma cells

artículo científico publicado en 2001

Citrullinated glucose-regulated protein 78 is an autoantigen in type 1 diabetes

artículo científico publicado en 2014

Classification of current anticancer immunotherapies

artículo científico publicado en 2014

Concomitant inhibition of AKT and autophagy is required for efficient cisplatin-induced apoptosis of metastatic skin carcinoma.

artículo científico publicado en 2010

Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells

artículo científico publicado en 2014

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Consensus guidelines for the detection of immunogenic cell death

artículo científico publicado en 2014

Coordination of stress, Ca2+, and immunogenic signaling pathways by PERK at the endoplasmic reticulum

artículo científico publicado en 2016

DAMP-Induced Allograft and Tumor Rejection: The Circle Is Closing.

artículo científico publicado en 2016

DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown ⬇️

artículo científico publicado el 24 de enero de 2011

Danger signalling during cancer cell death: origins, plasticity and regulation.

scientific article published on 17 May 2013

Death and survival signals in photodynamic therapy

artículo científico publicado en 2010

Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell-driven rejection of high-grade glioma

artículo científico publicado en 2016

Deregulation of cell-death pathways as the cornerstone of skin diseases.

artículo científico publicado en 2009

Distinct transduction mechanisms of cyclooxygenase 2 gene activation in tumour cells after photodynamic therapy

article

Dynamic interplay between autophagic flux and Akt during melanoma progression in vitro

artículo científico publicado en 2014

ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses.

artículo científico

ER stress-induced inflammation: does it aid or impede disease progression?

artículo científico publicado en 2012

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.

artículo científico publicado en 2017

Early responses in mitogenic signaling, bombesin induced protein phosphorylations in Swiss 3T3 cells.

artículo científico publicado en 1993

Editorial: Immunogenic Cell Death in Cancer: From Benchside Research to Bedside Reality

artículo científico publicado en 2016

Efficacy of antitumoral photodynamic therapy with hypericin: relationship between biodistribution and photodynamic effects in the RIF-1 mouse tumor model

artículo científico publicado en 2001

Elucidation of the tumoritropic principle of hypericin.

artículo científico publicado en 2005

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

artículo científico publicado en 2011

Epithelial-mesenchymal transition during invasion of cutaneous squamous cell carcinoma is paralleled by AKT activation

artículo científico publicado en 2014

Extracellular ATP and P₂X₇ receptor exert context-specific immunogenic effects after immunogenic cancer cell death.

artículo científico publicado en 2016

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress

artículo científico publicado en 2013

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

artículo científico publicado en 2008

High content analysis at single cell level identifies different cellular responses dependent on nanomaterial concentrations

artículo científico publicado en 2015

How to teach an old dog new tricks: autophagy-independent action of chloroquine on the tumor vasculature

artículo científico publicado en 2014

Hypericin as a potential phototherapeutic agent in superficial transitional cell carcinoma of the bladder

artículo científico publicado en 2004

Hypericin in cancer treatment: more light on the way.

artículo científico publicado en 2002

Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin ⬇️

artículo científico publicado el 23 de diciembre de 2011

Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis

scientific article published on 01 November 1998

Immature, Semi-Mature, and Fully Mature Dendritic Cells: Toward a DC-Cancer Cells Interface That Augments Anticancer Immunity

artículo científico publicado en 2013

Immunogenic cell death and DAMPs in cancer therapy

artículo científico publicado en 2012

Immunogenic cell death, DAMPs and anticancer therapeutics: an emerging amalgamation

artículo científico publicado en 2009

Immunogenic cell death.

artículo científico

Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation

artículo científico publicado en 2016

Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: A large-scale meta-analysis

artículo científico publicado en 2015

In vitro study of the photocytotoxicity of bathochromically-shifted hypericin derivatives

artículo científico publicado en 2009

Inducers of immunogenic cancer cell death.

artículo científico

Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy

artículo científico publicado en 2007

Inhibition of epidermal growth factor receptor tyrosine kinase activity by hypericin

artículo científico publicado en 1993

Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated

artículo científico publicado en 2011

Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes

artículo científico publicado en 2002

Integrating Next-Generation Dendritic Cell Vaccines into the Current Cancer Immunotherapy Landscape

artículo científico

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma

artículo científico publicado en 2015

JNK/SAPK activation by platelet-derived growth factor in A431 cells requires both the phospholipase C-gamma and the phosphatidylinositol 3-kinase signaling pathways of the receptor

artículo científico publicado en 1999

Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy.

artículo científico publicado en 2010

Melanoma targeting with the loco-regional chemotherapeutic, Melphalan: From cell death to immunotherapeutic efficacy

artículo científico publicado en 2015

Melphalan, Antimelanoma Immunity, and Inflammation--Response

article

Mitochondria are targets for peroxisome-derived oxidative stress in cultured mammalian cells

artículo científico publicado en 2013

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

artículo científico publicado en 2015

Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells.

artículo científico publicado en 2007

Molecular effectors of multiple cell death pathways initiated by photodynamic therapy

artículo científico publicado en 2007

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

NF-kappaB inhibition improves the sensitivity of human glioblastoma cells to 5-aminolevulinic acid-based photodynamic therapy.

artículo científico publicado en 2010

New functions of mitochondria associated membranes in cellular signaling.

artículo científico publicado en 2014

Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death

artículo científico publicado en 2014

ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function.

artículo científico publicado en 2016

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

artículo científico publicado en 2012

Pathogen response-like recruitment and activation of neutrophils by sterile immunogenic dying cells drives neutrophil-mediated residual cell killing

artículo científico publicado en 2017

Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis ⬇️

artículo científico publicado el 28 de junio de 2012

Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis.

artículo científico publicado en 2002

Phosphorylation of Yeast Plasma Membrane H+-ATPase by Casein Kinase I

artículo científico publicado en 1996

Phosphorylation of the modulator protein of the ATP,Mg-dependent protein phosphatase by casein kinase TS

scientific article published on 01 October 1986

Phosphorylation of the phosphatase modulator subunit (inhibitor-2) by casein kinase-1 Identification of the phosphorylation sites

artículo científico publicado en 1992

Photodynamic therapy of cancer: an update

artículo científico publicado en 2011

Photodynamic therapy with hypericin induces vascular damage and apoptosis in the RIF-1 mouse tumor model.

artículo científico publicado en 2002

Photodynamic therapy: illuminating the road from cell death towards anti-tumour immunity

artículo científico publicado en 2010

Photosensitized inhibition of growth factor-regulated protein kinases by hypericin

artículo científico publicado en 1995

Physical modalities inducing immunogenic tumor cell death for cancer immunotherapy

artículo científico publicado en 2014

Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma.

artículo científico

Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3.

artículo científico publicado en 2015

Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim.

artículo científico publicado en 2013

Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of endoplasmic reticulum stress and unfolded protein response

scientific article published on 12 May 2009

Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.

artículo científico publicado en 2016

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

artículo científico publicado en 2013

Rapid stimulation of Ser/Thr protein kinases following treatment of Swiss 3T3 cells with bombesin. Involvement of casein kinase-2 in the signaling pathway of bombesin ⬇️

artículo científico publicado el 15 de mayo de 1992

Regulatory pathways in photodynamic therapy induced apoptosis.

artículo científico publicado en 2004

Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal

artículo científico publicado en 2015

Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy

artículo científico publicado en 2006

SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity

artículo científico publicado en 2010

Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy

artículo científico publicado en 2017

Skin mild hypoxia enhances killing of UVB-damaged keratinocytes through reactive oxygen species-mediated apoptosis requiring Noxa and Bim.

artículo científico publicado en 2012

Spatiotemporal autophagic degradation of oxidatively damaged organelles after photodynamic stress is amplified by mitochondrial reactive oxygen species

artículo científico publicado en 2012

Specificity of the polycation-stimulated (type-2A) and ATP, Mg-dependent (type-1) protein phosphatases toward substrates phosphorylated by P34cdc2 kinase

artículo científico publicado en 1992

Starting and propagating apoptotic signals in UVB irradiated keratinocytes.

scientific article published on 05 January 2009

Staying in touch: Taking a closer look at ER-Golgi contact sites

artículo científico publicado en 2019

Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting

artículo científico publicado en 2021

Synthetic peptides as model substrates for the study of the specificity of the polycation-stimulated protein phosphatases

article

Targeted inhibition of p38alpha MAPK suppresses tumor-associated endothelial cell migration in response to hypericin-based photodynamic therapy

artículo científico publicado en 2005

Targeting ER stress induced apoptosis and inflammation in cancer.

artículo científico publicado en 2010

The ATP,Mg-dependent protein phosphatase: Regulation by casein kinase-1

artículo científico publicado en 1987

The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin

scientific article published in Journal of Biological Chemistry

The Aryl hydrocarbon receptor: an illuminating effector of the UVB response

artículo científico publicado en 2007

The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.

artículo científico publicado en 2015

The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling.

artículo científico publicado en 2017

The PERKs of damage-associated molecular patterns mediating cancer immunogenicity: From sensor to the plasma membrane and beyond.

artículo científico

The emergence of phox-ER stress induced immunogenic apoptosis ⬇️

artículo científico publicado el 1 de agosto de 2012

The flavonoid luteolin increases the resistance of normal, but not malignant keratinocytes, against UVB-induced apoptosis

artículo científico publicado en 2010

The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis

artículo científico publicado en 2013

The multifaceted photocytotoxic profile of hypericin

artículo científico publicado en 2009

The polycation-stimulated protein phosphatases: regulation and specificity

artículo científico publicado en 1987

Transplantation and Damage-Associated Molecular Patterns (DAMPs).

artículo científico publicado en 2016

Trial watch: Dendritic cell-based anticancer immunotherapy

artículo científico publicado en 2017

Tumor vessel normalization by chloroquine independent of autophagy.

artículo científico publicado en 2014

Ultraviolet B radiation-induced apoptosis in human keratinocytes: cytosolic activation of procaspase-8 and the role of Bcl-2.

artículo científico publicado en 2003

Uncovering the role of hypoxia inducible factor-1α in skin carcinogenesis.

artículo científico publicado en 2011

Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells

artículo científico publicado en 2003

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

artículo científico publicado en 2016

Vesicular trafficking mechanisms in endothelial cells as modulators of the tumor vasculature and targets of antiangiogenic therapies.

artículo científico

When under pressure, get closer: PERKing up membrane contact sites during ER stress

artículo científico publicado en 2016

p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis

artículo científico publicado en 2000

p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling

artículo científico publicado en 2013

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda