Lista de obras - Lars Bolund - Dominio Público Uruguay

A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues

artículo científico publicado en 2011

A lentiviral vector-based genetic sensor system for comparative analysis of permeability and activity of vitamin D3 analogues in xenotransplanted human skin

artículo científico publicado en 2013

A microarray analysis of the rice transcriptome and its comparison to Arabidopsis

artículo científico publicado en 2005

A population threshold for functional polymorphisms

artículo científico publicado en 2003

An improved PCR strategy for fast screening of specific and random integrations in rAAV-mediated gene targeted cell clones ⬇️

artículo científico publicado el 21 de julio de 2011

An improved method for genome wide DNA methylation profiling correlated to transcription and genomic instability in two breast cancer cell lines

artículo científico publicado en 2009

An update on targeted gene repair in mammalian cells: methods and mechanisms ⬇️

artículo científico publicado el 2 de febrero de 2011

Analyses of pig genomes provide insight into porcine demography and evolution

artículo científico publicado en 2012

Are keratoacanthomas variants of squamous cell carcinomas? A comparison of chromosomal aberrations by comparative genomic hybridization

artículo científico publicado en 2006

Array comparative genomic hybridization of keratoacanthomas and squamous cell carcinomas: different patterns of genetic aberrations suggest two distinct entities

artículo científico publicado en 2012

Aseptic minimum volume vitrification technique for porcine parthenogenetically activated blastocyst

artículo científico publicado el 1 de enero de 2011

Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts

artículo científico publicado en 2002

BS-SNPer: SNP calling in bisulfite-seq data

artículo científico publicado en 2015

Building the sequence map of the human pan-genome

artículo científico publicado en 2009

Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing

artículo científico publicado en 2014

Comparison of gene expression and genome-wide DNA methylation profiling between phenotypically normal cloned pigs and conventionally bred controls

artículo científico publicado en 2011

Computational Methods for Epigenetic Analysis: The Protocol of Computational Analysis for Modified Methylation-Specific Digital Karyotyping Based on Massively Parallel Sequencing ⬇️

artículo científico publicado el 1 de enero de 2011

DNA copy number aberrations in breast cancer by array comparative genomic hybridization

artículo científico publicado en 2009

DNA methylation in peripheral blood cells of pigs cloned by somatic cell nuclear transfer

artículo científico publicado en 2011

De novo assembly of a haplotype-resolved human genome.

artículo científico publicado en 2015

Development of transgenic minipigs with expression of antimorphic human cryptochrome 1

artículo científico publicado en 2013

Elevated NaCl concentration improves cryotolerance and developmental competence of porcine oocytes

artículo científico publicado en 2009

Epidermolysis bullosa simplex keratinocytes with extended lifespan established by ectopic expression of telomerase

artículo científico publicado en 2003

Erratum: The sequence and de novo assembly of the giant panda genome

artículo científico publicado en 2010

Estimation of tumor heterogeneity using CGH array data

artículo científico publicado en 2009

Exome sequencing identifies somatic point mutations associated with acquired endocrine resistance in breast cancer cell lines

artículo científico publicado en 2012

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB in Normal and Lesional Psoriatic Skin

Expression of short-chain acyl-CoA dehydrogenase (SCAD) proteins in the liver of SCAD deficient mice after hydrodynamic gene transfer

artículo científico publicado en 2003

Factors Determining the Efficiency of Porcine Somatic Cell Nuclear Transfer: Data Analysis with Over 200,000 Reconstructed Embryos

artículo científico publicado en 2015

Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant

artículo científico publicado en 2013

Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions

artículo científico publicado en 2012

Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

artículo científico publicado en 2007

Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases.

artículo científico publicado en 2018

Genomic organization, transcript variants and comparative analysis of the human nucleoporin 155 (NUP155) gene

artículo científico publicado en 2002

Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter

artículo científico publicado en 2003

Golden Gate Assembly of CRISPR gRNA expression array for simultaneously targeting multiple genes.

artículo científico publicado en 2016

GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China

artículo científico publicado en 2014

Handling of human short-chain acyl-CoA dehydrogenase (SCAD) variant proteins in transgenic mice

artículo científico publicado en 2007

Handmade cloned transgenic piglets expressing the nematode fat-1 gene

artículo científico publicado en 2012

Haplotype frequencies in a sub-region of chromosome 19q13.3, related to risk and prognosis of cancer, differ dramatically between ethnic groups

artículo científico publicado en 2009

Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw

artículo científico publicado en 2009

High hydrostatic pressure treatment of porcine oocytes before handmade cloning improves developmental competence and cryosurvival

artículo científico publicado en 2008

High hydrostatic pressure treatment of porcine oocytes induces parthenogenetic activation

artículo científico publicado en 2010

High-resolution mapping of genotype-phenotype relationships in cri du chat syndrome using array comparative genomic hybridization

artículo científico publicado en 2005

Identification of genetic aberrations on chromosome 22 outside the NF2 locus in schwannomatosis and neurofibromatosis type 2.

artículo científico publicado en 2005

Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research

artículo científico publicado en 2003

Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

artículo científico publicado en 2013

Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages

artículo científico publicado en 2015

Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP.

artículo científico publicado en 2008

Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotides

artículo científico publicado en 2002

Mesenchymal stem cells derived from human induced pluripotent stem cells retain adequate osteogenicity and chondrogenicity but less adipogenicity

artículo científico publicado en 2015

Misfolding, degradation, and aggregation of variant proteins. The molecular pathogenesis of short chain acyl-CoA dehydrogenase (SCAD) deficiency

artículo científico publicado en 2003

Mosaics and moles

artículo científico publicado en 2011

Mutation analysis in mitochondrial fatty acid oxidation defects: Exemplified by acyl-CoA dehydrogenase deficiencies, with special focus on genotype-phenotype relationship

artículo científico publicado en 2001

Novel loci and pathways significantly associated with longevity

artículo científico publicado en 2016

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios ⬇️

artículo científico publicado en 2015

Omics-based profiling of carcinoma of the breast and matched regional lymph node metastasis

article

Osmotic stress induced by sodium chloride, sucrose or trehalose improves cryotolerance and developmental competence of porcine oocytes

artículo científico publicado en 2009

Paternal Hemizygosity in 11p15 in Mole-like Conceptuses: Two Case Reports

artículo científico publicado en 2015

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

artículo científico publicado en 2017

Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences.

artículo científico publicado en 2011

Pig genome sequence--analysis and publication strategy

artículo científico publicado en 2010

Pig transgenesis by Sleeping Beauty DNA transposition

artículo científico publicado en 2010

PigGIS: Pig Genomic Informatics System

artículo científico publicado en 2006

Piglets born from vitrified cloned blastocysts produced with a simplified method of delipation and nuclear transfer

artículo científico publicado en 2007

Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing

artículo científico publicado en 2005

Platelet Derived Growth Factor (PDGF) Responsive Epidermis Formed from Human Keratinocytes Transduced with the PDGFβ Receptor Gene ⬇️

artículo científico publicado el 1 de mayo de 2003

Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags

artículo científico publicado en 2007

Production of Pigs by Hand-Made Cloning Using Mesenchymal Stem Cells and Fibroblasts

artículo científico publicado en 2016

Production of Retroviral Vectors in Primary Human Keratinocytes after DNA-Mediated Gene Transfer Leads to Prolonged Gene Expression ⬇️

artículo científico publicado el 1 de enero de 2003

Production of porcine blastocysts expressed EGFP by handmade cloning

artículo científico publicado en 2011

Protein misfolding, aggregation, and degradation in disease

artículo científico publicado en 2003

RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

artículo científico

Rapid genotyping of human ERCC1 exon 4 polymorphism with fluorescence analysis using fluorophore-labeled hybridization probes and a lightcycler

artículo científico publicado en 2002

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

SMAP: a streamlined methylation analysis pipeline for bisulfite sequencing

artículo científico publicado en 2015

SNP genotyping using microsphere-linked PNA and flow cytometric detection

artículo científico publicado en 2005

SOAPindel: efficient identification of indels from short paired reads

artículo científico publicado en 2012

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

artículo científico publicado en 2017

Sequencing bias: comparison of different protocols of MicroRNA library construction

article

Sequencing bias: comparison of different protocols of microRNA library construction

artículo científico publicado en 2010

Sequencing of 50 human exomes reveals adaptation to high altitude

artículo científico publicado en 2010

Sex Differences in Genetic Associations With Longevity

Short PNA molecular beacons for real-time PCR allelic discrimination of single nucleotide polymorphisms

artículo científico publicado en 2004

Side population cells in human and mouse epidermis lack stem cell characteristics

artículo científico publicado en 2004

Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm

artículo científico publicado en 2012

Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor

artículo científico publicado en 2012

Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer

artículo científico publicado en 2012

Site-specific strand bias in gene correction using single-stranded oligonucleotides

artículo científico publicado en 2004

Snap: an integrated SNP annotation platform

artículo científico publicado en 2006

State of the art de novo assembly of human genomes from massively parallel sequencing data

artículo científico publicado en 2010

Stress for stress tolerance? A fundamentally new approach in mammalian embryology

artículo científico publicado en 2010

Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly

artículo científico publicado en 2011

Targeted genome editing by recombinant adeno-associated virus (rAAV) vectors for generating genetically modified pigs

artículo científico publicado en 2012

Temporal dissection of tumorigenesis in primary cancers

artículo científico publicado en 2011

Tetraploidy in hydatidiform moles

artículo científico publicado en 2013

The ACADS gene variation spectrum in 114 patients with short-chain acyl-CoA dehydrogenase (SCAD) deficiency is dominated by missense variations leading to protein misfolding at the cellular level

artículo científico publicado en 2008

The DNA methylome of human peripheral blood mononuclear cells

artículo científico publicado en 2010

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

artículo científico publicado en 2013

The diploid genome sequence of an Asian individual

artículo científico publicado en 2008

The genome of the cucumber, Cucumis sativus L

artículo científico publicado en 2009

The parental origin correlates with the karyotype of human embryos developing from tripronuclear zygotes

artículo científico publicado en 2015

The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer

artículo científico publicado en 2015

The sequence and analysis of a Chinese pig genome

artículo científico publicado en 2012

The sequence and de novo assembly of the giant panda genome

artículo científico publicado en 2010

Towards Personalized Regenerative Cell Therapy: Mesenchymal Stem Cells Derived from Human Induced Pluripotent Stem Cells

artículo científico

Transgenic Wuzhishan minipigs designed to express a dominant-negative porcine growth hormone receptor display small stature and a perturbed insulin/IGF-1 pathway

artículo científico publicado en 2015

TreeFam: 2008 Update

artículo científico publicado en 2008

TreeFam: a curated database of phylogenetic trees of animal gene families

artículo científico publicado en 2006

Triploid pregnancies: genetic and clinical features of 158 cases

artículo científico

Triploidy--Observations in 154 Diandric Cases

artículo científico publicado en 2015

Tumor heterogeneity in neoplasms of breast, colon, and skin

artículo científico publicado en 2010

Twelve single nucleotide polymorphisms on chromosome 19q13.2-13.3: linkage disequilibria and associations with basal cell carcinoma in Danish psoriatic patients

artículo científico publicado en 2003

Twin pregnancies with diploid hydatidiform mole and co-existing normal fetus may originate from one oocyte

artículo científico publicado en 2008

Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

artículo científico publicado en 2014

WEGO 2.0: a web tool for analyzing and plotting GO annotations, 2018 update.

artículo científico publicado en 2018

Lista de obras de Lars Bolund

A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues

A lentiviral vector-based genetic sensor system for comparative analysis of permeability and activity of vitamin D3 analogues in xenotransplanted human skin

A microarray analysis of the rice transcriptome and its comparison to Arabidopsis

A population threshold for functional polymorphisms

An improved PCR strategy for fast screening of specific and random integrations in rAAV-mediated gene targeted cell clones ⬇️

An improved method for genome wide DNA methylation profiling correlated to transcription and genomic instability in two breast cancer cell lines

An update on targeted gene repair in mammalian cells: methods and mechanisms ⬇️

Analyses of pig genomes provide insight into porcine demography and evolution

Are keratoacanthomas variants of squamous cell carcinomas? A comparison of chromosomal aberrations by comparative genomic hybridization

Array comparative genomic hybridization of keratoacanthomas and squamous cell carcinomas: different patterns of genetic aberrations suggest two distinct entities

Aseptic minimum volume vitrification technique for porcine parthenogenetically activated blastocyst

Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts

BS-SNPer: SNP calling in bisulfite-seq data

Building the sequence map of the human pan-genome

Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing

Comparison of gene expression and genome-wide DNA methylation profiling between phenotypically normal cloned pigs and conventionally bred controls

Computational Methods for Epigenetic Analysis: The Protocol of Computational Analysis for Modified Methylation-Specific Digital Karyotyping Based on Massively Parallel Sequencing ⬇️

DNA copy number aberrations in breast cancer by array comparative genomic hybridization

DNA methylation in peripheral blood cells of pigs cloned by somatic cell nuclear transfer

De novo assembly of a haplotype-resolved human genome.

Development of transgenic minipigs with expression of antimorphic human cryptochrome 1

Elevated NaCl concentration improves cryotolerance and developmental competence of porcine oocytes

Epidermolysis bullosa simplex keratinocytes with extended lifespan established by ectopic expression of telomerase

Erratum: The sequence and de novo assembly of the giant panda genome

Estimation of tumor heterogeneity using CGH array data

Exome sequencing identifies somatic point mutations associated with acquired endocrine resistance in breast cancer cell lines

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB in Normal and Lesional Psoriatic Skin

Expression of short-chain acyl-CoA dehydrogenase (SCAD) proteins in the liver of SCAD deficient mice after hydrodynamic gene transfer

Factors Determining the Efficiency of Porcine Somatic Cell Nuclear Transfer: Data Analysis with Over 200,000 Reconstructed Embryos

Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant

Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions

Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases.

Genomic organization, transcript variants and comparative analysis of the human nucleoporin 155 (NUP155) gene

Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter

Golden Gate Assembly of CRISPR gRNA expression array for simultaneously targeting multiple genes.

GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China

Handling of human short-chain acyl-CoA dehydrogenase (SCAD) variant proteins in transgenic mice

Handmade cloned transgenic piglets expressing the nematode fat-1 gene

Haplotype frequencies in a sub-region of chromosome 19q13.3, related to risk and prognosis of cancer, differ dramatically between ethnic groups

Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw

High hydrostatic pressure treatment of porcine oocytes before handmade cloning improves developmental competence and cryosurvival

High hydrostatic pressure treatment of porcine oocytes induces parthenogenetic activation

High-resolution mapping of genotype-phenotype relationships in cri du chat syndrome using array comparative genomic hybridization

Identification of genetic aberrations on chromosome 22 outside the NF2 locus in schwannomatosis and neurofibromatosis type 2.

Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research

Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages

Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP.

Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotides

Mesenchymal stem cells derived from human induced pluripotent stem cells retain adequate osteogenicity and chondrogenicity but less adipogenicity

Misfolding, degradation, and aggregation of variant proteins. The molecular pathogenesis of short chain acyl-CoA dehydrogenase (SCAD) deficiency

Mosaics and moles

Mutation analysis in mitochondrial fatty acid oxidation defects: Exemplified by acyl-CoA dehydrogenase deficiencies, with special focus on genotype-phenotype relationship

Novel loci and pathways significantly associated with longevity

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios ⬇️

Omics-based profiling of carcinoma of the breast and matched regional lymph node metastasis

Osmotic stress induced by sodium chloride, sucrose or trehalose improves cryotolerance and developmental competence of porcine oocytes

Paternal Hemizygosity in 11p15 in Mole-like Conceptuses: Two Case Reports

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences.

Pig genome sequence--analysis and publication strategy

Pig transgenesis by Sleeping Beauty DNA transposition

PigGIS: Pig Genomic Informatics System

Piglets born from vitrified cloned blastocysts produced with a simplified method of delipation and nuclear transfer

Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing

Platelet Derived Growth Factor (PDGF) Responsive Epidermis Formed from Human Keratinocytes Transduced with the PDGFβ Receptor Gene ⬇️

Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags

Production of Pigs by Hand-Made Cloning Using Mesenchymal Stem Cells and Fibroblasts

Production of Retroviral Vectors in Primary Human Keratinocytes after DNA-Mediated Gene Transfer Leads to Prolonged Gene Expression ⬇️

Production of porcine blastocysts expressed EGFP by handmade cloning

Protein misfolding, aggregation, and degradation in disease

RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

Rapid genotyping of human ERCC1 exon 4 polymorphism with fluorescence analysis using fluorophore-labeled hybridization probes and a lightcycler

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

SMAP: a streamlined methylation analysis pipeline for bisulfite sequencing

SNP genotyping using microsphere-linked PNA and flow cytometric detection

SOAPindel: efficient identification of indels from short paired reads

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference