Lista de obras - Mathias Christmann - Dominio Público Uruguay

(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels

artículo científico publicado en 2015

A General One-Pot Synthesis of 2H-Indazoles Using an Organophosphorus-Silane System.

artículo científico publicado en 2018

A formal, one-pot β-chlorination of primary alcohols and its utilization in the transformation of terpene feedstock and the synthesis of a C2-symmetrical terminal bis-epoxide.

artículo científico publicado en 2014

Access to skipped polyene macrolides through ring-closing metathesis: total synthesis of the RNA polymerase inhibitor ripostatin B

artículo científico publicado en 2012

Amine-catalyzed cyclizations of tethered alpha,beta-unsaturated carbonyl compounds

artículo científico publicado en 2008

Asymmetric Synthesis of Carbocyclic Propellanes.

artículo científico publicado en 2017

Bioinspired synthesis of pentacyclic onocerane triterpenoids

artículo científico publicado en 2017

Chlorinated isomers of nonylphenol differ in estrogenic and androgenic activity

artículo científico publicado en 2011

Crossed intramolecular Rauhut-Currier-type reactions via dienamine activation

artículo científico publicado en 2009

Dienamine-Induced Divinylcyclopropane-Cycloheptadiene Rearrangements

scientific article published on 12 March 2019

Efficient synthesis and resolution of pyrrolizidines

artículo científico publicado en 2007

Enabling strategies for step efficient syntheses

artículo científico publicado en 2018

Enantiogroup-differentiating biocatalytic reductions of prochiral Cs -symmetrical dicarbonyl compounds to meso compounds.

artículo científico publicado en 2015

Enantioselective tandem reactions at elevated temperatures: one-pot hydroformylation/SN1 alkylation

artículo científico publicado en 2012

Enantioselective α- and γ-alkylation of α,β-unsaturated aldehydes using dienamine activation

artículo científico publicado en 2010

Five-Step Synthesis of Yaequinolones J1 and J2

scientific article published on 07 January 2020

Identification of an (-)-Englerin A analogue which antagonizes (-)-Englerin A at TRPC1/4/5 channels. ⬇️

artículo científico publicado en 2017

In Situ Synthesis and Applications for Polyinterhalides based on BrCl

scientific article published on 06 April 2020

Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi

artículo científico publicado en 2016

Mechanistic Studies on the Organocatalytic α-Chlorination of Aldehydes: The Role and Nature of Off-Cycle Intermediates

artículo científico publicado en 2018

Multivalent polyglycerol supported imidazolidin-4-one organocatalysts for enantioselective Friedel-Crafts alkylations

artículo científico publicado en 2015

N,N'-carbonyldiimidazole-mediated cyclization of amino alcohols to substituted azetidines and other N-heterocycles

artículo científico publicado en 2006

N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates

scientific article published on 07 January 2020

Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells ⬇️

artículo científico publicado en 2017

New developments in the asymmetric Stetter reaction

artículo científico publicado en 2005

One-Pot Synthesis of 5-Hydroxy-4H-1,3-thiazin-4-ones: Structure Revision, Synthesis, and NMR Shift Dependence of Thiasporine A.

artículo científico publicado en 2016

One-pot oxidation/isomerization of Z-allylic alcohols with oxygen as stoichiometric oxidant

artículo científico publicado en 2012

One-pot reactions accelerate the synthesis of active pharmaceutical ingredients

artículo científico publicado en 2011

Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles

artículo científico publicado en 2016

Otto Wallach: Founder of Terpene Chemistry and Nobel Laureate 1910 ⬇️

artículo científico publicado el 10 de diciembre de 2010

Oxidation of allylic and benzylic alcohols to aldehydes and carboxylic acids

artículo científico publicado en 2014

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels ⬇️

artículo científico publicado en 2017

Probing 2H-Indazoles as Templates for SGK1, Tie2, and SRC Kinase Inhibitors

artículo científico publicado en 2019

Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal

scientific article published on 11 December 2019

Rapid access to polyketide scaffolds via vinylogous Mukaiyama aldol reactions

artículo científico publicado en 2001

Scalable Synthesis of Functionalized Ferrocenyl Azides and Amines Enabled by Flow Chemistry

scientific article published on 15 January 2020

Selective oxidation of aliphatic C-H bonds in the synthesis of complex molecules

artículo científico publicado en 2008

Semisynthesis of Plant-Derived Englerin A Enabled by Microbe Engineering of Guaia-6,10(14)-diene as Building Block

scientific article published on 03 February 2020

Synthesis and Structure Revision of Dichrocephones A and B.

artículo científico publicado en 2017

Synthesis of (+)-Darwinolide, a Biofilm-Penetrating Anti-MRSA Agent

scientific article published on 18 December 2018

Synthesis of (+)-Greek Tobacco Lactone via a Diastereoablative Epoxidation and a Selenium-Catalyzed Oxidative Cyclization.

artículo científico publicado en 2017

Synthesis of (+)-Vitepyrroloid A and (+)-Vitepyrroloid B by Late-Stage Ni-Catalyzed C(sp2)-C(sp3) Cross-Electrophile Coupling

artículo científico publicado en 2018

Synthesis of Enantioenriched Bromohydrins via Divergent Reactions of Racemic Intermediates from Anchimeric Oxygen Borrowing

artículo científico publicado en 2018

Synthesis of Highly Enantioenriched Propelladienes and their Application as Ligands in Asymmetric Rh-Catalyzed 1,4-Additions

scientific article published on 14 August 2018

Synthesis of Quinolinone Alkaloids via Aryne Insertions into Unsymmetric Imides in Flow

artículo científico publicado en 2018

Synthesis of Spongidine A and D and Petrosaspongiolide L Methyl Ester Using Pyridine C-H Functionalization

artículo científico publicado en 2019

Synthesis of Thelepamide via Catalyst-Controlled 1,4-Addition of Cysteine Derivatives and Structure Revision of Thelepamide.

artículo científico publicado en 2018

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A ⬇️

article by Sin Ying Cheung et al published 3 July 2018 in Oncotarget

The chemistry and biology of ratjadone

artículo científico publicado en 2001

The first total synthesis of +-ratjadone

artículo científico publicado en 2001

Total Synthesis of (+)-Ratjadone

artículo científico publicado en 2000

Total synthesis and absolute configuration of the guaiane sesquiterpene englerin A.

artículo científico publicado en 2009

Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile

artículo científico publicado en 2011

Total synthesis of phorboxazole A via de novo oxazole formation: convergent total synthesis

scientific article published on 29 December 2010

Total synthesis of phorboxazole A via de novo oxazole formation: strategy and component assembly

artículo científico publicado en 2010

Total synthesis: towards artificial terpene cyclases.

artículo científico publicado en 2010

Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis

artículo científico publicado en 2018

Transforming terpene feedstock into polyketide architecture

scientific article published on 10 September 2010

Transforming terpene-derived aldehydes into 1,2-epoxides via asymmetric α-chlorination: subsequent epoxide opening with carbon nucleophiles

artículo científico publicado en 2011

β-Lactones through catalytic asymmetric heterodimerization of ketenes

artículo científico publicado en 2012

Lista de obras de Mathias Christmann

(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels

A General One-Pot Synthesis of 2H-Indazoles Using an Organophosphorus-Silane System.

A formal, one-pot β-chlorination of primary alcohols and its utilization in the transformation of terpene feedstock and the synthesis of a C2-symmetrical terminal bis-epoxide.

Access to skipped polyene macrolides through ring-closing metathesis: total synthesis of the RNA polymerase inhibitor ripostatin B

Amine-catalyzed cyclizations of tethered alpha,beta-unsaturated carbonyl compounds

Asymmetric Synthesis of Carbocyclic Propellanes.

Bioinspired synthesis of pentacyclic onocerane triterpenoids

Chlorinated isomers of nonylphenol differ in estrogenic and androgenic activity

Crossed intramolecular Rauhut-Currier-type reactions via dienamine activation

Dienamine-Induced Divinylcyclopropane-Cycloheptadiene Rearrangements

Efficient synthesis and resolution of pyrrolizidines

Enabling strategies for step efficient syntheses

Enantiogroup-differentiating biocatalytic reductions of prochiral Cs -symmetrical dicarbonyl compounds to meso compounds.

Enantioselective tandem reactions at elevated temperatures: one-pot hydroformylation/SN1 alkylation

Enantioselective α- and γ-alkylation of α,β-unsaturated aldehydes using dienamine activation

Five-Step Synthesis of Yaequinolones J1 and J2

Identification of an (-)-Englerin A analogue which antagonizes (-)-Englerin A at TRPC1/4/5 channels. ⬇️

In Situ Synthesis and Applications for Polyinterhalides based on BrCl

Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi

Mechanistic Studies on the Organocatalytic α-Chlorination of Aldehydes: The Role and Nature of Off-Cycle Intermediates

Multivalent polyglycerol supported imidazolidin-4-one organocatalysts for enantioselective Friedel-Crafts alkylations

N,N'-carbonyldiimidazole-mediated cyclization of amino alcohols to substituted azetidines and other N-heterocycles

N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates

Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells ⬇️

New developments in the asymmetric Stetter reaction

One-Pot Synthesis of 5-Hydroxy-4H-1,3-thiazin-4-ones: Structure Revision, Synthesis, and NMR Shift Dependence of Thiasporine A.

One-pot oxidation/isomerization of Z-allylic alcohols with oxygen as stoichiometric oxidant

One-pot reactions accelerate the synthesis of active pharmaceutical ingredients

Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles

Otto Wallach: Founder of Terpene Chemistry and Nobel Laureate 1910 ⬇️

Oxidation of allylic and benzylic alcohols to aldehydes and carboxylic acids

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels ⬇️

Probing 2H-Indazoles as Templates for SGK1, Tie2, and SRC Kinase Inhibitors

Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal

Rapid access to polyketide scaffolds via vinylogous Mukaiyama aldol reactions

Scalable Synthesis of Functionalized Ferrocenyl Azides and Amines Enabled by Flow Chemistry

Selective oxidation of aliphatic C-H bonds in the synthesis of complex molecules

Semisynthesis of Plant-Derived Englerin A Enabled by Microbe Engineering of Guaia-6,10(14)-diene as Building Block

Synthesis and Structure Revision of Dichrocephones A and B.

Synthesis of (+)-Darwinolide, a Biofilm-Penetrating Anti-MRSA Agent

Synthesis of (+)-Greek Tobacco Lactone via a Diastereoablative Epoxidation and a Selenium-Catalyzed Oxidative Cyclization.

Synthesis of (+)-Vitepyrroloid A and (+)-Vitepyrroloid B by Late-Stage Ni-Catalyzed C(sp2)-C(sp3) Cross-Electrophile Coupling

Synthesis of Enantioenriched Bromohydrins via Divergent Reactions of Racemic Intermediates from Anchimeric Oxygen Borrowing

Synthesis of Highly Enantioenriched Propelladienes and their Application as Ligands in Asymmetric Rh-Catalyzed 1,4-Additions

Synthesis of Quinolinone Alkaloids via Aryne Insertions into Unsymmetric Imides in Flow

Synthesis of Spongidine A and D and Petrosaspongiolide L Methyl Ester Using Pyridine C-H Functionalization

Synthesis of Thelepamide via Catalyst-Controlled 1,4-Addition of Cysteine Derivatives and Structure Revision of Thelepamide.

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A ⬇️

The chemistry and biology of ratjadone

The first total synthesis of +-ratjadone

Total Synthesis of (+)-Ratjadone

Total synthesis and absolute configuration of the guaiane sesquiterpene englerin A.

Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile

Total synthesis of phorboxazole A via de novo oxazole formation: convergent total synthesis

Total synthesis of phorboxazole A via de novo oxazole formation: strategy and component assembly

Total synthesis: towards artificial terpene cyclases.

Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis

Transforming terpene feedstock into polyketide architecture

Transforming terpene-derived aldehydes into 1,2-epoxides via asymmetric α-chlorination: subsequent epoxide opening with carbon nucleophiles

β-Lactones through catalytic asymmetric heterodimerization of ketenes