Lista de obras - Martin Irmler - Dominio Público Uruguay

A Vitamin E-Enriched Antioxidant Diet Interferes with the Acute Adaptation of the Liver to Physical Exercise in Mice.

artículo científico publicado en 2018

A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue

artículo científico publicado en 2017

A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling.

artículo científico publicado en 2015

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

artículo científico publicado en 2016

AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex

scientific journal article

AP2γ Regulates Basal Progenitor Fate and Upper Layer Neuron Specification in the Mouse Cerebral Cortex

APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth

artículo científico publicado en 1998

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

artículo científico publicado en 2017

Activated B cells express functional Fas ligand

scientific article published on 01 March 1996

Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance

scientific article published on 23 January 2017

An approach to handling and interpretation of ambiguous data in transcriptome and proteome comparisons

artículo científico publicado en 2008

Astrocyte reactivity after brain injury-: The role of galectins 1 and 3.

artículo científico publicado en 2015

Author Correction: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates

artículo científico

BrainProfileDB - a platform for integration of functional genomics data

artículo científico publicado en 2008

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

artículo científico publicado en 2000

Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD.

artículo científico publicado en 2014

Cleavage of caspase family members by granzyme B: a comparative study in vitro

artículo científico publicado en 1997

Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism

artículo científico publicado en 2021

Creatine improves health and survival of mice

artículo científico publicado en 2008

Cytokine response of primary human myotubes in an in vitro exercise model

artículo científico publicado en 2013

Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring

artículo científico publicado en 2015

Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice

artículo científico

Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus

artículo científico publicado en 2015

Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4.

artículo científico publicado en 1997

Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

artículo científico publicado en 2016

Epithelial cell plasticity drives endoderm formation during gastrulation

artículo científico publicado en 2021

Erratum: Corrigendum: AP2γ regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex

scholarly article published in Nature Neuroscience

FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.

artículo científico publicado en 1998

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes

artículo científico publicado en 2015

Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation

artículo científico publicado en 2013

GDNF-induced osteopontin from Müller glial cells promotes photoreceptor survival in the Pde6brd1 mouse model of retinal degeneration

artículo científico publicado en 2011

Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling

artículo científico publicado en 2011

Generation of pancreatic β cells from CD177+ anterior definitive endoderm

scientific article published on 27 April 2020

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors

artículo científico publicado en 2018

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

artículo científico publicado en 2015

Identification of C/EBPβ target genes in ALK+ anaplastic large cell lymphoma (ALCL) by gene expression profiling and chromatin immunoprecipitation

artículo científico publicado en 2013

Identification of proliferative and mature β-cells in the islets of Langerhans

artículo científico publicado en 2016

Impact of fibroblast growth factor 21 on the secretome of human perivascular preadipocytes and adipocytes: a targeted proteomics approach

artículo científico publicado en 2016

Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation

artículo científico publicado en 2011

In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells

artículo científico publicado en 2010

In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis

artículo científico publicado en 2012

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

artículo científico publicado en 2020

Inhibition of death receptor signals by cellular FLIP

artículo científico publicado en 1997

Inhibition of fas death signals by FLIPs

artículo científico publicado en 1998

Integration of transcriptomics, proteomics, and microRNA analyses reveals novel microRNA regulation of targets in the mammalian inner ear

artículo científico publicado en 2011

Interlocking transcriptomics, proteomics and toponomics technologies for brain tissue analysis in murine hippocampus

artículo científico publicado en 2008

Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.

artículo científico publicado en 1996

Liver adapts mitochondrial function to insulin resistant and diabetic states in mice

artículo científico publicado en 2013

Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients

artículo científico publicado en 2012

MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression

artículo científico publicado en 2017

Maternal Pre-Pregnancy Obesity Is Associated with Altered Placental Transcriptome

artículo científico publicado en 2017

MicroRNA profiling with correlation to gene expression revealed the oncogenic miR-17-92 cluster to be up-regulated in osteosarcoma

artículo científico publicado en 2012

Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia

article

Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection

artículo científico publicado en 2017

Neurons induced to express major histocompatibility complex class I antigen are killed via the perforin and not the Fas (APO-1/CD95) pathway

artículo científico publicado en 1996

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists

artículo científico publicado en 2004

Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates

artículo científico

Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice

artículo científico publicado en 2014

Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice

artículo científico publicado en 2009

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis

artículo científico publicado en 2013

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma

artículo científico publicado en 2010

Point mutations in the PDX1 transactivation domain impair human β-cell development and function

Production and release of acylcarnitines by primary myotubes reflect the differences in fasting fat oxidation of the donors

artículo científico publicado en 2013

Prospective isolation of functionally distinct radial glial subtypes--lineage and transcriptome analysis.

artículo científico publicado en 2008

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung

artículo científico publicado en 2020

Pulmonary CCR2+CD4+ T cells are immune regulatory and attenuate lung fibrosis development

artículo científico publicado en 2017

Quantification of regenerative potential in primary human mammary epithelial cells

artículo científico publicado en 2015

Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome-wide expression analysis

artículo científico

Secretome profiling of primary human skeletal muscle cells

artículo científico publicado en 2013

Selective expression of FLIP in malignant melanocytic skin lesions

artículo científico publicado en 2001

Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells

artículo científico publicado en 2013

Simple derivation of transgene-free iPS cells by a dual recombinase approach

artículo científico publicado en 2014

Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation

artículo científico publicado en 2015

TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle

artículo científico publicado en 2016

Targeted estrogen delivery reverses the metabolic syndrome

artículo científico publicado en 2012

Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo

artículo científico publicado en 2016

The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.

artículo científico

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

artículo científico publicado en 2000

The endothelin system in human glioblastoma.

artículo científico publicado en 2000

The global gene expression profile of the secondary transition during pancreatic development

artículo científico publicado en 2015

The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival

artículo científico publicado en 2013

The transcription factor Otx2 regulates choroid plexus development and function

artículo científico publicado en 2013

Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications

artículo científico publicado en 2010

Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes

artículo científico publicado en 2015

Transcriptome analysis of MENX-associated rat pituitary adenomas identifies novel molecular mechanisms involved in the pathogenesis of human pituitary gonadotroph adenomas

artículo científico publicado en 2013

Transcriptome and proteome analysis of early embryonic mouse brain development.

artículo científico publicado en 2008

Transcriptomic analysis comparing mouse strains with extreme total lung capacities identifies novel candidate genes for pulmonary function

artículo científico

Trnp1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate

scientific journal article

Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery

artículo científico publicado en 2015

Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity

scientific article published on 11 August 2020

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic

artículo científico publicado en 2017

Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay

artículo científico publicado en 2015

microRNA cluster 106a~363 is involved in T helper 17 cell differentiation

artículo científico publicado en 2017

Lista de obras de Martin Irmler

A Vitamin E-Enriched Antioxidant Diet Interferes with the Acute Adaptation of the Liver to Physical Exercise in Mice.

A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue

A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling.

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex

AP2γ Regulates Basal Progenitor Fate and Upper Layer Neuron Specification in the Mouse Cerebral Cortex

APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

Activated B cells express functional Fas ligand

Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance

An approach to handling and interpretation of ambiguous data in transcriptome and proteome comparisons

Astrocyte reactivity after brain injury-: The role of galectins 1 and 3.

Author Correction: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates

BrainProfileDB - a platform for integration of functional genomics data

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD.

Cleavage of caspase family members by granzyme B: a comparative study in vitro

Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism

Creatine improves health and survival of mice

Cytokine response of primary human myotubes in an in vitro exercise model

Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring

Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice

Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus

Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4.

Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy

Epithelial cell plasticity drives endoderm formation during gastrulation

Erratum: Corrigendum: AP2γ regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex

FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes

Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation

GDNF-induced osteopontin from Müller glial cells promotes photoreceptor survival in the Pde6brd1 mouse model of retinal degeneration

Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling

Generation of pancreatic β cells from CD177+ anterior definitive endoderm

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

Identification of C/EBPβ target genes in ALK+ anaplastic large cell lymphoma (ALCL) by gene expression profiling and chromatin immunoprecipitation

Identification of proliferative and mature β-cells in the islets of Langerhans

Impact of fibroblast growth factor 21 on the secretome of human perivascular preadipocytes and adipocytes: a targeted proteomics approach

Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation

In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells

In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

Inhibition of death receptor signals by cellular FLIP

Inhibition of fas death signals by FLIPs

Integration of transcriptomics, proteomics, and microRNA analyses reveals novel microRNA regulation of targets in the mammalian inner ear

Interlocking transcriptomics, proteomics and toponomics technologies for brain tissue analysis in murine hippocampus

Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.

Liver adapts mitochondrial function to insulin resistant and diabetic states in mice

Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients

MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression

Maternal Pre-Pregnancy Obesity Is Associated with Altered Placental Transcriptome

MicroRNA profiling with correlation to gene expression revealed the oncogenic miR-17-92 cluster to be up-regulated in osteosarcoma

Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia

Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection

Neurons induced to express major histocompatibility complex class I antigen are killed via the perforin and not the Fas (APO-1/CD95) pathway

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists

Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates

Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice

Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma

Point mutations in the PDX1 transactivation domain impair human β-cell development and function

Production and release of acylcarnitines by primary myotubes reflect the differences in fasting fat oxidation of the donors

Prospective isolation of functionally distinct radial glial subtypes--lineage and transcriptome analysis.

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung

Pulmonary CCR2+CD4+ T cells are immune regulatory and attenuate lung fibrosis development

Quantification of regenerative potential in primary human mammary epithelial cells

Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome-wide expression analysis

Secretome profiling of primary human skeletal muscle cells

Selective expression of FLIP in malignant melanocytic skin lesions

Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells

Simple derivation of transgene-free iPS cells by a dual recombinase approach

Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation

TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle

Targeted estrogen delivery reverses the metabolic syndrome

Targeting PI3K/mTOR signaling exerts potent antitumor activity in pheochromocytoma in vivo

The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

The endothelin system in human glioblastoma.