Lista de obras - Dónal O'Carroll - Dominio Público Uruguay

220-plex microRNA expression profile of a single cell

artículo científico publicado en 2006

A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming

artículo científico publicado en 2017

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

artículo científico publicado en 2007

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

artículo científico publicado en 2019

A transit-amplifying population underpins the efficient regenerative capacity of the testis.

artículo científico publicado en 2017

Argonaute2 mediates compensatory expansion of the pancreatic β cell

artículo científico publicado en 2013

Blimp1 and the emergence of the germ line during development in the mouse.

artículo científico publicado en 2005

Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland

scientific journal article

Blimp1 is a critical determinant of the germ cell lineage in mice

artículo científico publicado en 2005

Blimp1 regulates the transition of neonatal to adult intestinal epithelium

artículo científico publicado en 2011

Cerebellar neurodegeneration in the absence of microRNAs

artículo científico publicado en 2007

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

artículo científico publicado en 2010

Defective germline reprogramming rewires the spermatogonial transcriptome

Deficiency in the nuclear long noncoding RNA causes myogenic defects and heart remodeling in mice

artículo científico publicado en 2018

Dicer is selectively important for the earliest stages of erythroid development.

artículo científico publicado en 2012

Dicer-dependent microRNA pathway safeguards regulatory T cell function

artículo científico publicado en 2008

Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein

artículo científico publicado en 2016

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

artículo científico publicado en 2014

Essential role for Argonaute2 protein in mouse oogenesis

artículo científico publicado en 2009

Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells.

artículo científico publicado en 2017

Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.

artículo científico publicado en 2017

G9a co-suppresses LINE1 elements in spermatogonia.

artículo científico publicado en 2014

General principals of miRNA biogenesis and regulation in the brain.

artículo científico publicado en 2012

Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells

artículo científico publicado en 2010

Germline recruitment in mice: a genetic program for epigenetic reprogramming.

artículo científico publicado en 2006

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance

artículo científico publicado en 2015

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.

artículo científico

Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression

artículo científico publicado en 2000

JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells

artículo científico publicado en 2021

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

artículo científico publicado en 2001

Maternal microRNAs are essential for mouse zygotic development

scientific journal article

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

artículo científico publicado en 2001

MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

artículo científico publicado en 2008

MicroRNA degradation by a conserved target RNA regulates animal behavior.

artículo científico publicado en 2018

MicroRNA-128 governs neuronal excitability and motor behavior in mice

artículo científico publicado en 2013

MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo

artículo científico publicado en 2008

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs

scientific journal article

Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis

scientific journal article

NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

artículo científico publicado en 2021

Oligoasthenoteratozoospermia and infertility in mice deficient for miR-34b/c and miR-449 loci

artículo científico publicado en 2014

PIWI-interacting RNAs: small RNAs with big functions

artículo científico publicado en 2019

Quantitative functions of Argonaute proteins in mammalian development.

artículo científico publicado en 2012

Regulation of chromatin structure by site-specific histone H3 methyltransferases

artículo científico publicado en 2000

Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs.

artículo científico publicado en 2010

SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation

artículo científico publicado en 2020

TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing

artículo científico publicado en 2020

Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia

scientific article published on 25 April 2019

Terminal uridylyltransferases target RNA viruses as part of the innate immune system

scientific article published on 13 August 2018

The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

artículo científico publicado en 2017

The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.

artículo científico publicado en 2017

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements

scientific journal article

The miR-144/451 locus is required for erythroid homeostasis

artículo científico publicado en 2010

The miR-144/451eGFP allele, a novel tool for resolving the erythroid potential of hematopoietic precursors.

artículo científico publicado en 2011

The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.

artículo científico publicado en 1999

The polycomb-group gene Ezh2 is required for early mouse development

artículo científico publicado en 2001

Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution

artículo científico publicado en 2017

mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome

artículo científico publicado en 2017

Lista de obras de Dónal O'Carroll

220-plex microRNA expression profile of a single cell

A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

A transit-amplifying population underpins the efficient regenerative capacity of the testis.

Argonaute2 mediates compensatory expansion of the pancreatic β cell

Blimp1 and the emergence of the germ line during development in the mouse.

Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland

Blimp1 is a critical determinant of the germ cell lineage in mice

Blimp1 regulates the transition of neonatal to adult intestinal epithelium

Cerebellar neurodegeneration in the absence of microRNAs

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

Defective germline reprogramming rewires the spermatogonial transcriptome

Deficiency in the nuclear long noncoding RNA causes myogenic defects and heart remodeling in mice

Dicer is selectively important for the earliest stages of erythroid development.

Dicer-dependent microRNA pathway safeguards regulatory T cell function

Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

Essential role for Argonaute2 protein in mouse oogenesis

Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells.

Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.

G9a co-suppresses LINE1 elements in spermatogonia.

General principals of miRNA biogenesis and regulation in the brain.

Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells

Germline recruitment in mice: a genetic program for epigenetic reprogramming.

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.

Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression

JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

Maternal microRNAs are essential for mouse zygotic development

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

MicroRNA degradation by a conserved target RNA regulates animal behavior.

MicroRNA-128 governs neuronal excitability and motor behavior in mice

MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs

Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis

NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

Oligoasthenoteratozoospermia and infertility in mice deficient for miR-34b/c and miR-449 loci

PIWI-interacting RNAs: small RNAs with big functions

Quantitative functions of Argonaute proteins in mammalian development.

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs.

SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation

TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing

Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia

Terminal uridylyltransferases target RNA viruses as part of the innate immune system

The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements

The miR-144/451 locus is required for erythroid homeostasis

The miR-144/451eGFP allele, a novel tool for resolving the erythroid potential of hematopoietic precursors.

The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.

The polycomb-group gene Ezh2 is required for early mouse development

Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution

mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome