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Lista de obras de Ewa Sikora

"Mitotic Slippage" and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres

scientific article published on 16 April 2020

A common signature of cellular senescence; does it exist?

artículo científico publicado en 2021

A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta

artículo científico publicado en 2013

A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells.

artículo científico publicado en 1999

A quinazoline antifolate as inhibitor of folate metabolism in mouse L-cells

scientific article published on 01 January 1983

ATM-deficient neural precursors develop senescence phenotype with disturbances in autophagy

artículo científico publicado en 2020

Activation of a low pH-dependent nuclease by apoptotic agents

artículo científico publicado en 1999

Activation-induced and damage-induced cell death in aging human T cells

artículo científico publicado en 2015

Age, Sex, and BMI Influence on Copper, Zinc, and Their Major Serum Carrier Proteins in a Large European Population Including Nonagenarian Offspring From MARK-AGE Study

artículo científico publicado en 2021

Age- and tumour-related changes in methionine biosynthesis in mice

scientific article published on 01 August 1986

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

artículo científico publicado en 2016

Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study

artículo científico publicado en 2021

Ageing, longevity, exceptional longevity and related genetic and non genetics markers: panel statement

artículo científico publicado en 2014

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

artículo científico publicado en 2016

Antigen presentation capability and AP-1 activation accompany methotrexate-induced colon cancer cell senescence in the context of aberrant β-catenin signaling

artículo científico publicado en 2021

Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study

artículo científico publicado en 2018

Apoptosis-like, reversible changes in plasma membrane asymmetry and permeability, and transient modifications in mitochondrial membrane potential induced by curcumin in rat thymocytes

artículo científico publicado en 1998

Association between fat-soluble vitamins and self-reported health status: a cross-sectional analysis of the MARK-AGE cohort

artículo científico publicado en 2021

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

artículo científico

Bacterial DNAemia in Older Participants and Nonagenarian Offspring and Association With Redox Biomarkers: Results From MARK-AGE Study

artículo científico publicado en 2022

Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice.

artículo científico publicado en 2017

Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?

artículo científico publicado en 2017

Cellular Senescence in Brain Aging

artículo científico publicado en 2021

Cellular senescence in ageing, age-related disease and longevity.

artículo científico publicado en 2014

Chromatin-Directed Proteomics Identifies ZNF84 as a p53-Independent Regulator of p21 in Genotoxic Stress Response

artículo científico publicado en 2021

Circulating cell-free DNA in health and disease — the relationship to health behaviours, ageing phenotypes and metabolomics

artículo científico publicado en 2022

Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile

artículo científico publicado en 2022

Comparison of folylderivative biosynthesis in Ehrlich ascites carcinoma cells and in some organs of healthy and tumor-bearing mice

artículo científico publicado en 1984

Curcumin Affects Components of the Chromosomal Passenger Complex and Induces Mitotic Catastrophe in Apoptosis-Resistant Bcr-Abl-Expressing Cells

artículo científico publicado en 2006

Curcumin abolishes apoptosis resistance of calcitriol-differentiated HL-60 cells

artículo científico publicado en 2006

Curcumin disrupts meiotic and mitotic divisions via spindle impairment and inhibition of CDK1 activity.

artículo científico publicado en 2010

Curcumin elevates sirtuin level but does not postpone in vitro senescence of human cells building the vasculature.

artículo científico publicado en 2016

Curcumin induces caspase-3-dependent apoptotic pathway but inhibits DNA fragmentation factor 40/caspase-activated DNase endonuclease in human Jurkat cells

scientific article published on 01 April 2006

Curcumin induces cell death without oligonucleosomal DNA fragmentation in quiescent and proliferating human CD8+ cells

scientific article published on 02 September 2006

Curcumin induces multiple signaling pathways leading to vascular smooth muscle cell senescence

artículo científico publicado en 2019

Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells

artículo científico publicado en 2015

Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy

artículo científico publicado en 2012

Curcumin induces senescence of primary human cells building the vasculature in a DNA damage and ATM-independent manner

artículo científico publicado en 2015

Curcumin, inflammation, ageing and age-related diseases.

artículo científico publicado en 2010

Curcumin-treated cancer cells show mitotic disturbances leading to growth arrest and induction of senescence phenotype

artículo científico publicado en 2016

DNA damage-independent apoptosis induced by curcumin in normal resting human T cells and leukaemic Jurkat cells

artículo científico publicado en 2013

Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project

artículo científico publicado en 2011

Development of an assay for the estimation of N10-propargyl-5,8-dideazafolic acid polyglutamates in tumor cells

artículo científico publicado en 1988

Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents

artículo científico publicado en 2019

Do low molecular weight antioxidants contribute to the Protection against oxidative damage? The interrelation between oxidative stress and low molecular weight antioxidants based on data from the MARK-AGE study

artículo científico publicado en 2021

Do we already know the death gene?

artículo científico publicado en 1995

Early loss of proliferative potential of human peritoneal mesothelial cells in culture: the role of p16INK4a-mediated premature senescence.

artículo científico publicado en 2005

Effect of aging on UVC-induced apoptosis of rat splenocytes

scientific article published on 01 January 2000

Effect of curcumin on the apoptosis of rodent and human nonproliferating and proliferating lymphoid cells.

artículo científico publicado en 2000

Expression of oncogenic kinase Bcr-Abl impairs mitotic checkpoint and promotes aberrant divisions and resistance to microtubule-targeting agents

artículo científico publicado en 2010

Folate enzymes in Ehrlich ascites carcinoma-bearing mice

artículo científico publicado en 1984

Formation and retention and biological activity of N10-propargyl-5,8-dideazafolic acid (CB3717) polyglutamates in L1210 cells in vitro

scientific article published on 01 November 1988

Formation of AP1 transcriptional complex in concanavalin A-stimulated splenocytes derived from young and old mice

artículo científico publicado el 21 de noviembre de 1992

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study

artículo científico publicado en 2019

Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

artículo científico publicado en 2007

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

artículo científico publicado en 2013

Glutathione-independent mechanism of apoptosis inhibition by curcumin in rat thymocytes

scientific article published on 01 October 1998

Growth Properties and Growth Factor Responsiveness in Skin Fibroblasts from Centenarians

artículo científico publicado en 1998

High-resolution quantitative metabolome analysis of urine by automated flow injection NMR.

artículo científico publicado en 2013

Impact of cellular senescence signature on ageing research

artículo científico publicado en 2010

Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of Breast Cancer Cells

artículo científico publicado en 2020

Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage

artículo científico publicado en 2012

Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells

artículo científico publicado en 2008

Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells.

artículo científico publicado en 2012

Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells

scientific article published on 08 December 2020

Inhibition of proliferation and apoptosis of human and rat T lymphocytes by curcumin, a curry pigment

scientific article published on 01 October 1997

Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells

artículo científico publicado en 2018

Insights Into Sibling Relationships and Longevity From Genetics of Healthy Ageing Nonagenarians: The Importance of Optimisation, Resilience and Social Networks

artículo científico publicado en 2022

Interference between DNA binding activities of AP-1 and GR transcription factors in rat thymocytes undergoing dexamethasone-induced apoptosis.

artículo científico publicado en 1996

Is DNA damage indispensable for stress-induced senescence?

artículo científico publicado en 2017

Is senescence-associated β-galactosidase a marker of neuronal senescence?

scientific article published on 19 October 2016

Loss of transcription factor AP-1 DNA binding activity during lymphocyte aging in vivo

scientific article published on 01 November 1992

MARK-AGE biomarkers of ageing

artículo científico publicado en 2015

MARK-AGE population: From the human model to new insights

artículo científico publicado en 2015

Medication Intake Is Associated with Lower Plasma Carotenoids and Higher Fat-Soluble Vitamins in the Cross-Sectional MARK-AGE Study in Older Individuals

artículo científico publicado en 2020

Metabolism of folate glutamates in Aspergillus nidulans

scientific article published on 01 January 1993

Methotrexate-induced senescence in human adenocarcinoma cells is accompanied by induction of p21(waf1/cip1) expression and lack of polyploidy.

artículo científico publicado en 2009

Microbiome in Blood Samples From the General Population Recruited in the MARK-AGE Project: A Pilot Study

artículo científico publicado en 2021

Morphological and Functional Characteristic of Senescent Cancer Cells.

artículo científico

NOX4 downregulation leads to senescence of human vascular smooth muscle cells.

artículo científico publicado en 2016

Oxidative stress and inhibition of nitric oxide generation underlie methotrexate-induced senescence in human colon cancer cells

artículo científico publicado en 2017

P-glycoprotein expression does not change the apoptotic pathway induced by curcumin in HL-60 cells

artículo científico publicado en 2003

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries

artículo científico publicado en 2016

Polish Centenarians Programme. Multidisciplinary studies of successful ageing: aims, methods, and preliminary results

artículo científico publicado en 2007

Polyglutamation of the antifolate anticancer drug N10-propargyl-5,8-dideazafolic acid (CB 3717) in the mouse

scientific article published on 01 July 1986

Polyploid giant cancer cells: An emerging new field of cancer biology

artículo científico publicado en 2022

Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence

artículo científico publicado en 2015

Prevalence and loads of torquetenovirus (TTV) in the European MARK-AGE Study population

artículo científico publicado en 2019

Proliferation and apoptosis of human CD8(+)CD28(+) and CD8(+)CD28(-) lymphocytes during aging.

artículo científico publicado en 2004

Proliferation and apoptosis of human T cells during replicative senescence--a critical approach.

artículo científico publicado en 2000

Proliferation of CD8+ in culture of human T cells derived from peripheral blood of adult donors and cord blood of newborns

scientific article published on 01 April 2003

Proliferation-dependency of gamma-glutamyl hydrolase activity in various mouse cells

artículo científico publicado el 1 de abril de 1992

Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study

artículo científico publicado en 2017

Quality control data of physiological and immunological biomarkers measured in serum and plasma

artículo científico publicado en 2015

Rejuvenation of senescent cells—The road to postponing human aging and age-related disease? ⬇️

artículo científico publicado el 11 de octubre de 2012

Relationships between cancer and aging: a multilevel approach

artículo científico publicado en 2009

Replicative senescence of interleukin-2-dependent human T lymphocytes. Flow cytometric characteristics of phenotype changes

artículo científico publicado en 2000

Resistance to apoptosis of HCW-2 cells can be overcome by curcumin- or vincristine-induced mitotic catastrophe

artículo científico publicado en 2006

Resveratrol Derivative, 3,3',4,4'-Tetrahydroxy-trans-Stilbene, Retards Senescence of Mesothelial Cells via Hormetic-Like Prooxidative Mechanism.

artículo científico publicado en 2014

Role of annexin A6 isoforms in catecholamine secretion by PC12 cells: distinct influence on calcium response.

artículo científico publicado en 2010

Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains

artículo científico publicado en 2021

Separation of N-(4-aminobenzoyl)-gamma-oligo(L-glutamic acid)s on a thin-layer plate and their quantitation using fluorescamine

artículo científico publicado en 1988

Simultaneous induction and blockade of autophagy by a single agent.

artículo científico publicado en 2018

Sirtuins, a promising target in slowing down the ageing process.

artículo científico publicado en 2017

Studies of the relationship between cell proliferation and cell death. III. AP-1 DNA-binding activity during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes

artículo científico publicado en 1993

Studies on successful aging and longevity: Polish Centenarian Program.

artículo científico publicado en 2000

THERAPY-INDUCED POLYPLOIDIZATION AND SENESCENCE; COINCIDENCE OR INTERCONNECTION?

artículo científico publicado en 2020

TMA but not TMAO increases with age in rat plasma and affects smooth muscle cells viability

scientific article published on 14 August 2019

TMA, A Forgotten Uremic Toxin, but Not TMAO, Is Involved in Cardiovascular Pathology

artículo científico publicado en 2019

Targeting normal and cancer senescent cells as a strategy of senotherapy

artículo científico publicado en 2019

The Future of Ageing: not more of the same.

artículo científico publicado en 2017

The Role of Curcumin in the Modulation of Ageing ⬇️

artículo científico

The challenges in moving from ageing to successful longevity

artículo científico publicado en 2014

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

artículo científico publicado en 2013

The impaired transcription factor AP-1 DNA binding activity in lymphocytes derived from subjects with some symptoms of premature aging

artículo científico publicado en 1993

The promise of slow down ageing may come from curcumin.

artículo científico publicado en 2010

The role of active forms of oxygen in cell differentiation, neoplasm promotion and aging

artículo científico publicado en 1989

The role of autophagy in escaping therapy-induced polyploidy/senescence

artículo científico publicado en 2021

The role of gender and labour status in immunosenescence of 65+ Polish population

artículo científico publicado en 2017

The role of nibrin in doxorubicin-induced apoptosis and cell senescence in Nijmegen Breakage Syndrome patients lymphocytes

artículo científico publicado en 2014

Therapy-Induced Senescent/Polyploid Cancer Cells Undergo Atypical Divisions Associated with Altered Expression of Meiosis, Spermatogenesis and EMT Genes

artículo científico publicado en 2022

Transcription factors DNA-binding activity in rat thymocytes undergoing apoptosis after heat-shock or dexamethasone treatment

artículo científico publicado en 1993

UVC-induced cell death of IL-2-dependent human lymphocytes

scientific article published on 01 January 1999

Unbiased proteomic analysis of extracellular vesicles secreted by senescent human vascular smooth muscle cells reveals their ability to modulate immune cell functions

artículo científico publicado en 2022

Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization

artículo científico publicado en 2020

What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?

artículo científico publicado en 2005

What is and what is not cell senescence

scientific article published on 01 October 2018

Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project

artículo científico publicado en 2017

[Aging and longevity]

scientific article published in 2014

[Cell cycle and apoptosis: death of a senescent cell]

artículo científico publicado en 1996

[Immortality, cellular aging and death of cells. Role of protooncogenes, oncogenes and anti-oncogenes]

scientific article published on 01 January 1993

[Mechanism of programmed cell death (apoptosis)]

artículo científico publicado en 1994

[Molecular and cellular mechanisms of curcumin action--beneficial effect on organism]

artículo científico publicado en 2011

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