Lista de obras - Graham Simmons - Dominio Público Uruguay

A 3.4-Å cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles

scientific article published on 11 August 2020

A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.

artículo científico publicado en 1997

A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease

artículo científico publicado en 2013

A novel rhabdovirus associated with acute hemorrhagic fever in central Africa

artículo científico publicado en 2012

A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms

artículo científico publicado en 2010

A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.

artículo científico publicado en 2000

Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States

artículo científico publicado en 2010

Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity

artículo científico publicado en 1998

An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope

artículo científico publicado en 2018

Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Plasma using a Coronavirus Antigen Microarray

artículo científico publicado en 2020

Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray

artículo científico publicado en 2021

Arbovirus Diagnostics: From Bad to Worse due to Expanding Dengue Virus Vaccination and Zika Virus Epidemics

artículo científico publicado en 2017

Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enh

artículo científico publicado en 2004

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress

artículo científico publicado en 2015

CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry

artículo científico publicado en 1997

Cell-to-cell fusion, but not virus entry in macrophages by T-cell line tropic HIV-1 strains: a V3 loop-determined restriction

artículo científico publicado en 1995

Characterization of Chikungunya pseudotyped viruses: Identification of refractory cell lines and demonstration of cellular tropism differences mediated by mutations in E1 glycoprotein

artículo científico publicado en 2009

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

scholarly article

Characterization of the Bas-Congo virus glycoprotein and its function in pseudotyped viruses

artículo científico publicado en 2013

Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease

artículo científico publicado en 2011

Coreceptor ligand inhibition of fetal brain cell infection by HIV type 1.

artículo científico publicado en 1999

DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.

artículo científico publicado en 2003

DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus

artículo científico publicado en 2004

Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection

artículo científico publicado en 2012

Development and application of a high-throughput microneutralization assay: lack of xenotropic murine leukemia virus-related virus and/or murine leukemia virus detection in blood donors

artículo científico publicado en 2012

Development of novel entry inhibitors targeting emerging viruses

artículo científico publicado en 2012

Development of sensitive single-round pol or env RT-PCR assays to screen for XMRV in multiple sample types

artículo científico publicado en 2011

Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion

artículo científico publicado en 2011

Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR

artículo científico publicado en 2003

Differential activation of CC chemokine receptors by AOP-RANTES

artículo científico publicado en 2000

Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63.

artículo científico publicado en 2009

Duration of Dengue Viremia in Blood Donors and Relationships Between Donor Viremia, Infection Incidence and Clinical Case Reports During a Large Epidemic

artículo científico publicado en 2016

Ebola Virus Neutralizing Antibodies Detectable in Survivors of theYambuku, Zaire Outbreak 40 Years after Infection

artículo científico publicado en 2017

Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence

artículo científico publicado en 2002

Emerging infectious agents and the nation's blood supply: responding to potential threats in the 21st century ⬇️

artículo científico publicado el 13 de junio de 2012

Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry

artículo científico publicado en 2006

Evidence for a post-entry barrier to R5 HIV-1 infection of CD4 memory T cells

artículo científico publicado en 2001

Expanded tropism and altered activation of a retroviral glycoprotein resistant to an entry inhibitor peptide

artículo científico publicado en 2006

Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy

artículo científico publicado en 2014

Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study

artículo científico publicado en 2011

Filovirus Entry ⬇️

artículo científico publicado el 1 de enero de 2013

Filoviruses utilize glycosaminoglycans for their attachment to target cells

artículo científico publicado en 2013

First cases of Zika virus-infected US blood donors outside states with areas of active transmission

artículo científico publicado en 2017

Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection

artículo científico publicado en 2003

HIV-1 tropism and co-receptor use

scientific article published in Nature

High Incidence of Chikungunya Virus and Frequency of Viremic Blood Donations during Epidemic, Puerto Rico, USA, 2014

artículo científico publicado en 2016

Higher Serum Alanine Transaminase Levels in Male Urokinase-Type Plasminogen Activator-Transgenic Mice Are Associated With Improved Engraftment of Hepatocytes but not Liver Sinusoidal Endothelial Cells

artículo científico publicado en 2016

Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors

artículo científico publicado en 2006

Host genetic basis for hepatitis C virus clearance: a role for blood collection centers

artículo científico publicado en 2010

Human keratinocytes restrict chikungunya virus replication at a post-fusion step

artículo científico publicado en 2014

Identification of murine T-cell epitopes in Ebola virus nucleoprotein

artículo científico publicado en 2004

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer

artículo científico publicado en 2012

Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2.

artículo científico publicado en 2010

Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin

artículo científico publicado en 2011

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay

artículo científico publicado en 2011

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

artículo científico publicado en 2005

Inhibitory antibodies targeting emerging viruses: advancements and mechanisms

artículo científico publicado en 2016

Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses

artículo científico publicado en 2015

Is CD4 sufficient for HIV entry? Cell surface molecules involved in HIV infection

artículo científico publicado en 1993

Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis

artículo científico publicado en 2015

No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome

artículo científico publicado en 2011

No evidence of murine leukemia virus-related viruses in live attenuated human vaccines

artículo científico publicado en 2011

No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected

artículo científico publicado en 2011

Phylogenetic analysis of multiple heterosexual transmission events involving subtype b of HIV type 1.

artículo científico publicado en 2001

Plasma transfusion–transmission of Zika virus in mice and macaques

artículo científico publicado en 2023

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

artículo científico publicado en 1997

Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity

artículo científico publicado en 2007

Pseudotyping Viral Vectors With Emerging Virus Envelope Proteins

artículo científico publicado en 2016

SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques

scientific article published on 08 July 2020

SARS-CoV-2 infection induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

scientific article published on 14 August 2020

The Blood Xenotropic Murine Leukemia Virus–Related Virus Scientific Research Working Group: mission, progress, and plans ⬇️

artículo científico publicado el 1 de marzo de 2011

The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR.

artículo científico publicado en 2006

The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies

artículo científico publicado en 2013

Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques

artículo científico publicado en 2017

Lista de obras de Graham Simmons

A 3.4-Å cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles

A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.

A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease

A novel rhabdovirus associated with acute hemorrhagic fever in central Africa

A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms

A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.

Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States

Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity

An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope

Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Plasma using a Coronavirus Antigen Microarray

Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray

Arbovirus Diagnostics: From Bad to Worse due to Expanding Dengue Virus Vaccination and Zika Virus Epidemics

Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enh

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress

CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry

Cell-to-cell fusion, but not virus entry in macrophages by T-cell line tropic HIV-1 strains: a V3 loop-determined restriction

Characterization of Chikungunya pseudotyped viruses: Identification of refractory cell lines and demonstration of cellular tropism differences mediated by mutations in E1 glycoprotein

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

Characterization of the Bas-Congo virus glycoprotein and its function in pseudotyped viruses

Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease

Coreceptor ligand inhibition of fetal brain cell infection by HIV type 1.

DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.

DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus

Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection

Development and application of a high-throughput microneutralization assay: lack of xenotropic murine leukemia virus-related virus and/or murine leukemia virus detection in blood donors

Development of novel entry inhibitors targeting emerging viruses

Development of sensitive single-round pol or env RT-PCR assays to screen for XMRV in multiple sample types

Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion

Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR

Differential activation of CC chemokine receptors by AOP-RANTES

Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63.

Duration of Dengue Viremia in Blood Donors and Relationships Between Donor Viremia, Infection Incidence and Clinical Case Reports During a Large Epidemic

Ebola Virus Neutralizing Antibodies Detectable in Survivors of theYambuku, Zaire Outbreak 40 Years after Infection

Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence

Emerging infectious agents and the nation's blood supply: responding to potential threats in the 21st century ⬇️

Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry

Evidence for a post-entry barrier to R5 HIV-1 infection of CD4 memory T cells

Expanded tropism and altered activation of a retroviral glycoprotein resistant to an entry inhibitor peptide

Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy

Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study

Filovirus Entry ⬇️

Filoviruses utilize glycosaminoglycans for their attachment to target cells

First cases of Zika virus-infected US blood donors outside states with areas of active transmission

Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection

HIV-1 tropism and co-receptor use

High Incidence of Chikungunya Virus and Frequency of Viremic Blood Donations during Epidemic, Puerto Rico, USA, 2014

Higher Serum Alanine Transaminase Levels in Male Urokinase-Type Plasminogen Activator-Transgenic Mice Are Associated With Improved Engraftment of Hepatocytes but not Liver Sinusoidal Endothelial Cells

Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors

Host genetic basis for hepatitis C virus clearance: a role for blood collection centers

Human keratinocytes restrict chikungunya virus replication at a post-fusion step

Identification of murine T-cell epitopes in Ebola virus nucleoprotein

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer

Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2.

Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

Inhibitory antibodies targeting emerging viruses: advancements and mechanisms

Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses

Is CD4 sufficient for HIV entry? Cell surface molecules involved in HIV infection

Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis

No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome

No evidence of murine leukemia virus-related viruses in live attenuated human vaccines

No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected

Phylogenetic analysis of multiple heterosexual transmission events involving subtype b of HIV type 1.

Plasma transfusion–transmission of Zika virus in mice and macaques

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity

Pseudotyping Viral Vectors With Emerging Virus Envelope Proteins

SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques

SARS-CoV-2 infection induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

The Blood Xenotropic Murine Leukemia Virus–Related Virus Scientific Research Working Group: mission, progress, and plans ⬇️

The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR.

The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies

Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques