Lista de obras - Paulo De Sepulveda - Dominio Público Uruguay

Characterization of S628N: a novel KIT mutation found in a metastatic melanoma.

artículo científico publicado en 2014

Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma

artículo científico publicado en 2017

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.

artículo científico publicado en 2017

Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms

artículo científico publicado en 2003

FES kinase participates in KIT-ligand induced chemotaxis

artículo científico publicado en 2010

In aggressive forms of mastocytosis, TET2 loss cooperates with c-KITD816V to transform mast cells

artículo científico publicado en 2012

Insight on Mutation-Induced Resistance from Molecular Dynamics Simulations of the Native and Mutated CSF-1R and KIT

artículo científico publicado en 2016

KIT-D816V oncogenic activity is controlled by the juxtamembrane docking site Y568-Y570.

artículo científico publicado en 2013

Lnk adaptor protein down-regulates specific Kit-induced signaling pathways in primary mast cells

artículo científico publicado en 2008

Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells

artículo científico publicado en 2011

Multiple neuroendocrine tumours in transgenic mice induced by c-kit-SV40 T antigen fusion genes

artículo científico publicado en 1997

Overexpression of suppressor of cytokine signaling-1 impairs pre-T-cell receptor-induced proliferation but not differentiation of immature thymocytes

artículo científico publicado en 2001

Pediatric mastocytosis-associated KIT extracellular domain mutations exhibit different functional and signaling properties compared with KIT-phosphotransferase domain mutations.

artículo científico publicado en 2010

SARs do not impair position-dependent expression of a kit/lacZ transgene

scientific article published on 01 June 1995

SRC-Family Kinases in Acute Myeloid Leukaemia and Mastocytosis

scientific article published on 21 July 2020

SRSF2-p95 hotspot mutation is highly associated with advanced forms of mastocytosis and mutations in epigenetic regulator genes

artículo científico publicado en 2014

Signal transduction by several KIT juxtamembrane domain mutations

artículo científico publicado en 2003

Spontaneous STAT5 activation induces growth factor independence in idiopathic myelofibrosis: possible relationship with FKBP51 overexpression.

artículo científico publicado en 2003

Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling

artículo científico publicado en 2004

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

artículo científico publicado en 2000

The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins

artículo científico publicado en 2006

The tumor suppressor activity of SOCS-1.

artículo científico publicado en 2002

Lista de obras de Paulo De Sepulveda

Characterization of S628N: a novel KIT mutation found in a metastatic melanoma.

Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.

Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms

FES kinase participates in KIT-ligand induced chemotaxis

In aggressive forms of mastocytosis, TET2 loss cooperates with c-KITD816V to transform mast cells

Insight on Mutation-Induced Resistance from Molecular Dynamics Simulations of the Native and Mutated CSF-1R and KIT

KIT-D816V oncogenic activity is controlled by the juxtamembrane docking site Y568-Y570.

Lnk adaptor protein down-regulates specific Kit-induced signaling pathways in primary mast cells

Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells

Multiple neuroendocrine tumours in transgenic mice induced by c-kit-SV40 T antigen fusion genes

Overexpression of suppressor of cytokine signaling-1 impairs pre-T-cell receptor-induced proliferation but not differentiation of immature thymocytes

Pediatric mastocytosis-associated KIT extracellular domain mutations exhibit different functional and signaling properties compared with KIT-phosphotransferase domain mutations.

SARs do not impair position-dependent expression of a kit/lacZ transgene

SRC-Family Kinases in Acute Myeloid Leukaemia and Mastocytosis

SRSF2-p95 hotspot mutation is highly associated with advanced forms of mastocytosis and mutations in epigenetic regulator genes

Signal transduction by several KIT juxtamembrane domain mutations

Spontaneous STAT5 activation induces growth factor independence in idiopathic myelofibrosis: possible relationship with FKBP51 overexpression.

Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins

The tumor suppressor activity of SOCS-1.