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Lista de obras de Philip Rosenstiel

(-)-Deprenyl fails to promote axonal regeneration of retinal ganglion cells in vitro and in vivo

artículo científico publicado en 2002

1152 AUTOPHAGY INHIBITS COLORECTAL CARCINOGENESIS INDUCED BY COLIBACTIN-PRODUCING ESCHERICHIA COLI

artículo científico publicado en 2020

47 INFECTION WITH COLIBACTIN-PRODUCING ESCHERICHIA COLI TRIGGERS THE APPEARANCE OF ADENOMATOUS LESIONS IN A NOVEL MOUSE MODEL OF COLORECTAL CARCINOGENESIS

artículo científico publicado en 2021

A Novel Eukaryotic Denitrification Pathway in Foraminifera

scientific article published on 02 August 2018

A Phage Protein Aids Bacterial Symbionts in Eukaryote Immune Evasion

scientific article published on 24 September 2019

A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine

artículo científico publicado en 2017

A comprehensive, cell specific microRNA catalogue of human peripheral blood.

artículo científico publicado en 2017

A dietary flavone confers communicable protection against colitis through NLRP6 signaling independently of inflammasome activation.

artículo científico publicado en 2017

A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians

artículo científico publicado en 2009

A functional methylome map of ulcerative colitis

artículo científico publicado en 2012

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

artículo científico publicado en 2007

A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis

scientific journal article

A genome-wide association study reveals evidence of association with sarcoidosis at 6p12.1.

artículo científico publicado en 2011

A model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention

artículo científico publicado en 2018

A multi-parent recombinant inbred line population of C. elegans allows identification of novel QTLs for complex life history traits

artículo científico publicado en 2019

A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1

artículo científico publicado en 2012

A powerful method for transcriptional profiling of specific cell types in eukaryotes: laser-assisted microdissection and RNA sequencing

artículo científico publicado en 2012

A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion

artículo científico publicado en 2008

A shell regeneration assay to identify biomineralization candidate genes in mytilid mussels

artículo científico publicado en 2016

A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways

artículo científico publicado en 2006

A tissue-specific landscape of sense/antisense transcription in the mouse intestine

artículo científico publicado en 2011

ABSSeq: a new RNA-Seq analysis method based on modelling absolute expression differences

artículo científico publicado en 2016

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

scientific journal article

ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.

artículo científico publicado en 2018

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING

artículo científico publicado en 2018

Ablation of gly96/immediate early gene-X1 (gly96/iex-1) aggravates DSS-induced colitis in mice: role for gly96/iex-1 in the regulation of NF-kappaB.

scientific article published on February 2010

Absence of major histocompatibility complex class II mediated immunity in pipefish, Syngnathus typhle: evidence from deep transcriptome sequencing.

artículo científico publicado en 2013

Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing

artículo científico publicado en 2012

Activating Transcription Factor 6 Mediates Inflammatory Signals in Intestinal Epithelial Cells Upon Endoplasmic Reticulum Stress

artículo científico publicado en 2020

Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease

artículo científico publicado en 2002

Age-dependent expression of stress and antimicrobial genes in the hemocytes and siphon tissue of the Antarctic bivalve, Laternula elliptica, exposed to injury and starvation

artículo científico publicado en 2014

Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1

artículo científico publicado en 2011

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis

artículo científico publicado en 2016

Alterations of pre-mRNA splicing in human inflammatory bowel disease

article

Alternative Evolutionary Paths to Bacterial Antibiotic Resistance Cause Distinct Collateral Effects

artículo científico publicado en 2017

An improved filtering algorithm for big read datasets and its application to single-cell assembly.

artículo científico publicado en 2017

Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells

artículo científico publicado en 2005

Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing

artículo científico

Angiotensin AT2 receptor ligands: do they have potential as future treatments for neurological disease?

artículo científico publicado en 2002

Apomictic and sexual germline development differ with respect to cell cycle, transcriptional, hormonal and epigenetic regulation

artículo científico publicado en 2014

Assessing the fraction of short-distance tandem splice sites under purifying selection

artículo científico publicado en 2008

Association between clinical antibiotic resistance and susceptibility of Pseudomonas in the cystic fibrosis lung.

artículo científico publicado en 2016

Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies

scientific article published on 25 April 2013

Association of inflammatory bowel disease risk loci with sarcoidosis, and its acute and chronic subphenotypes.

artículo científico publicado en 2010

Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis

artículo científico publicado en 2012

Autophagy receptor CALCOCO2/NDP52 takes center stage in Crohn disease.

artículo científico publicado en 2013

Autophagy: A Novel Mechanism Involved in the Anti-Inflammatory Abilities of Probiotics

artículo científico publicado en 2019

Base-pair resolution DNA methylome of the EBV-positive Endemic Burkitt lymphoma cell line DAUDI determined by SOLiD bisulfite-sequencing.

artículo científico publicado en 2013

Beyond blood pressure: new roles for angiotensin II.

artículo científico publicado en 1999

Biophysical and Population Genetic Models Predict the Presence of "Phantom" Stepping Stones Connecting Mid-Atlantic Ridge Vent Ecosystems

artículo científico publicado en 2016

Both copy number and sequence variations affect expression of human DEFB4.

artículo científico publicado en 2010

Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling

artículo científico publicado en 2010

Cell-autonomous hepatocyte-specific GP130 signalling is sufficient to trigger a robust innate immune response in mice

artículo científico publicado en 2020

Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy

article published in the Proceedings of the National Academy of Sciences of the United States of America

Cerebrospinal fluid from patients with neurodegenerative and neuroninflammatory diseases: no evidence for rat glial activation in vitro

article

Characteristic changes in microbial community composition and expression of innate immune genes in acute appendicitis.

artículo científico publicado en 2013

Characterization of changes in serum anti-glycan antibodies in Crohn's disease--a longitudinal analysis

artículo científico publicado en 2011

Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections

scientific article published on 21 September 2020

Coagulation and inflammation. Molecular insights and diagnostic implications

artículo científico publicado en 2010

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

artículo científico publicado en 2011

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction

artículo científico publicado en 2016

Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms

scientific article published on 14 September 2019

Complete Genome Sequence of Bacillus thuringiensis Strain 407 Cry-.

artículo científico publicado en 2013

Complete genome sequence of the nematicidal Bacillus thuringiensis MYBT18247.

artículo científico publicado en 2017

Comprehensive assessment of sequence variation within the copy number variable defensin cluster on 8p23 by target enriched in-depth 454 sequencing

artículo científico publicado en 2011

Concentration of circulating miRNA-containing particles in serum enhances miRNA detection and reflects CRC tissue-related deregulations.

artículo científico publicado en 2016

Constant splice-isoform ratios in human lymphoblastoid cells support the concept of a splico-stat

artículo científico publicado en 2011

Contrasting invertebrate immune defense behaviors caused by a single gene, the Caenorhabditis elegans neuropeptide receptor gene npr-1

artículo científico publicado en 2016

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

artículo científico publicado en 2010

DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands

artículo científico publicado en 2009

DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.

artículo científico publicado en 2017

DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development.

artículo científico publicado en 2017

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

artículo científico publicado en 2015

DSS-induced acute colitis in C57BL/6 mice is mitigated by sulforaphane pre-treatment

artículo científico publicado en 2013

DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses

artículo científico publicado en 2009

Debug Your Bugs - How NLRs Shape Intestinal Host-Microbe Interactions

artículo científico

Debugging the intestinal microbiota in IBD

artículo científico publicado en 2009

Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.

artículo científico publicado en 2009

Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

artículo científico publicado en 2010

Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.

artículo científico publicado en 2017

Defining the Origins of the NOD-Like Receptor System at the Base of Animal Evolution

scientific article published on 23 December 2010

Dietary history contributes to enterotype-like clustering and functional metagenomic content in the intestinal microbiome of wild mice.

artículo científico publicado en 2014

Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease

scientific article published on 14 April 2020

Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology

artículo científico

Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole exome sequencing.

artículo científico publicado en 2017

Differential activity and expression of mitogen-activated protein kinases in inflammatory bowel disease

Differential effects of immunophilin-ligands (FK506 and V-10,367) on survival and regeneration of rat retinal ganglion cells in vitro and after optic nerve crush in vivo

artículo científico publicado en 2003

Differential p38 mitogen-activated protein kinase target phosphorylation in responders and nonresponders to infliximab

artículo científico publicado en 2003

Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays

artículo científico publicado en 2005

Distinct metabolic network states manifest in the gene expression profiles of pediatric inflammatory bowel disease patients and controls

artículo científico publicado en 2016

Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota.

artículo científico publicado en 2015

Dynamic changes of the luminal and mucosa-associated gut microbiota during and after antibiotic therapy with paromomycin

artículo científico publicado en 2015

ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells

artículo científico publicado en 2013

Effects of β-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea

artículo científico publicado en 2014

Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium difficile Infection.

artículo científico publicado en 2016

Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1.

artículo científico publicado en 2010

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

artículo científico publicado en 2016

Epigenetic dynamics of monocyte-to-macrophage differentiation

artículo científico publicado en 2016

Epigenetics of Inflammatory Bowel Disease

article

Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development

artículo científico publicado en 2016

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation

artículo científico publicado en 2016

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

artículo científico publicado en 2018

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

scientific article published on 01 March 2019

Erratum: Corrigendum: Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis

scholarly article published in Nature Genetics

Erratum: Corrigendum: Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin

artículo científico publicado en 2016

Erratum: Corrigendum: Sarcoidosis is associated with a truncating splice site mutation in the gene BTNL2

article

Erratum: Corrigendum: Signatures of mutational processes in human cancer

artículo científico publicado en 2013

Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease.

artículo científico publicado en 2006

Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases.

artículo científico publicado en 2018

Evolution and function of innate immune receptors--insights from marine invertebrates

artículo científico publicado en 2009

Evolutionary Transition from Pathogenicity to Commensalism: Global Regulator Mutations Mediate Fitness Gains through Virulence Attenuation

artículo científico publicado en 2015

Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen

artículo científico publicado en 2019

Experimental evolution of immunological specificity

artículo científico publicado en 2019

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.

artículo científico publicado en 2018

Expression signatures, barriers and beyond: the role of oxidative stress in murine colitis and human inflammatory bowel disease revisited

artículo científico publicado en 2008

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

artículo científico publicado en 2012

Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice

artículo científico publicado en 2012

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

scientific article published on 01 February 2020

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

scientific article published on 01 January 2020

FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy

artículo científico publicado en 2009

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β

artículo científico publicado en 2019

Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease

artículo científico publicado en 2018

FoxO is a critical regulator of stem cell maintenance in immortal Hydra

artículo científico publicado en 2012

FoxO is a critical regulator of stem cell maintenance in immortal Hydra: Proceedings of the National Academy of Sciences: Vol. 109, pp. 19697-19702, 2012.

artículo científico publicado en 2013

From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software

artículo científico publicado en 2012

From theory to therapy: implications from an in vitro model of ramified microglia

artículo científico publicado en 2001

Functional Expression of NOD2 in Freshly Isolated Human Peripheral Blood γδ T Cells

Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression

artículo científico publicado en 2007

Fungal rDNA signatures in coronary atherosclerotic plaques

artículo científico publicado en 2007

Fungi and inflammatory bowel diseases: Alterations of composition and diversity

artículo científico publicado en 2008

G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation

artículo científico publicado en 2009

GATA transcription factor as a likely key regulator of the Caenorhabditis elegans innate immune response against gut pathogens

artículo científico publicado en 2016

Gene expression and physiological changes of different populations of the long-lived bivalve Arctica islandica under low oxygen conditions

artículo científico publicado en 2012

Genetic Variants in Matrix Metalloproteinase Genes Are Associated With Development of Gastric Ulcer in H. Pylori Infection

artículo científico publicado en 2006

Genetic control of global gene expression levels in the intestinal mucosa: a human twin study

artículo científico publicado en 2009

Genetic evidence for PLASMINOGEN as a shared genetic risk factor of coronary artery disease and periodontitis

artículo científico publicado en 2014

Genetic interplay between human longevity and metabolic pathways - a large-scale eQTL study

artículo científico publicado en 2017

Genetic modification of hearing in tubby mice: evidence for the existence of a major gene (moth1) which protects tubby mice from hearing loss

artículo científico publicado en 1999

Genetic variants of the copy number polymorphic beta-defensin locus are associated with sporadic prostate cancer

artículo científico publicado en 2008

Genetic variation in DLG5 is associated with inflammatory bowel disease

artículo científico publicado en 2004

Genetics of Crohn disease, an archetypal inflammatory barrier disease

artículo científico publicado en 2005

Genetische Ätiologie bei chronisch-entzündlichen Darmerkrankungen

artículo científico publicado en 2014

Genome and low-iron response of an oceanic diatom adapted to chronic iron limitation

artículo científico publicado en 2012

Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci

scientific article published on 04 April 2017

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.

artículo científico publicado en 2016

Genome-wide association analysis in primary sclerosing cholangitis

artículo científico publicado en 2009

Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2.

artículo científico publicado en 2008

Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis

scientific journal article

Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci

artículo científico publicado en 2007

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).

artículo científico publicado en 2010

Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis

artículo científico publicado en 2008

Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.

artículo científico publicado en 2011

Genome-wide miRNA signatures of human longevity.

artículo científico publicado en 2012

Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci.

artículo científico publicado en 2016

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

artículo científico publicado en 2019

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

artículo científico publicado en 2015

Genomics of rapid adaptation to antibiotics: convergent evolution and scalable sequence amplification

artículo científico publicado en 2014

Geographical patterns of the standing and active human gut microbiome in health and IBD.

artículo científico publicado en 2015

Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma

artículo científico publicado en 2009

Germline variations of the topoisomerase IIα gene as risk factors for primary gastric B-cell lymphoma

article

Giant hydrogen sulfide plume in the oxygen minimum zone off Peru supports chemolithoautotrophy

artículo científico publicado en 2013

Grow With the Challenge - Microbial Effects on Epithelial Proliferation, Carcinogenesis, and Cancer Therapy

artículo científico publicado en 2018

HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells

artículo científico publicado en 2009

HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells

artículo científico publicado en 2008

HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells

artículo científico publicado en 2010

HLX1 gene variants influence the development of childhood asthma

artículo científico publicado en 2008

Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing

artículo científico publicado en 2010

High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes.

artículo científico publicado en 2008

Higher fetuin-A level is associated with coexistence of elevated alanine aminotransferase and the metabolic syndrome in the general population

artículo científico publicado en 2013

Highly potent host external immunity acts as a strong selective force enhancing rapid parasite virulence evolution.

artículo científico publicado en 2017

Host-Microbe Interactions in the Chemosynthetic Riftia pachyptila Symbiosis

scientific article published on 17 December 2019

Host-Pathogen Coevolution: The Selective Advantage of Bacillus thuringiensis Virulence and Its Cry Toxin Genes

artículo científico publicado en 2015

Hypothalamic Inflammation in Human Obesity Is Mediated by Environmental and Genetic Factors.

artículo científico publicado en 2017

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development

artículo científico publicado en 2010

IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis

artículo científico publicado en 2008

IL-1β and ADAM17 are central regulators of β-defensin expression in Candida esophagitis

artículo científico publicado en 2011

IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization

artículo científico publicado en 2016

IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation

artículo científico publicado en 2021

IL-27 Induced by Select Candida spp. via TLR7/NOD2 Signaling and IFN-β Production Inhibits Fungal Clearance

scientific article published on 03 June 2016

IRF-1Gene Variations Influence IgE Regulation and Atopy

article

Identification and characterization of two functional variants in the human longevity gene FOXO3.

artículo científico publicado en 2017

Identification, evolution, and association study of a novel promoter and first exon of the human NOD2 (CARD15) gene.

artículo científico publicado en 2007

Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine.

artículo científico publicado en 2018

Improving mapping and SNP-calling performance in multiplexed targeted next-generation sequencing

artículo científico publicado en 2012

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

artículo científico publicado en 2017

Increased expression of IL-16 in inflammatory bowel disease

artículo científico publicado en 2001

Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

artículo científico publicado en 2011

Induction of Periimplantitis in Dental Implants

artículo científico publicado en 2013

Infection routes matter in population-specific responses of the red flour beetle to the entomopathogen Bacillus thuringiensis

artículo científico publicado en 2014

Influence of CYP3A4, CYP3A5, and ABCB1 genotype and expression on budesonide pharmacokinetics: a possible role of intestinal CYP3A4 expression

artículo científico publicado en 2008

Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection

artículo científico publicado en 2006

Initial symbiont contact orchestrates host-organ-wide transcriptional changes that prime tissue colonization

artículo científico publicado en 2013

Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters

artículo científico publicado en 2018

Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn's Disease

artículo científico publicado en 2019

Interpreting whole genome and exome sequencing data of individual gastric cancer samples.

artículo científico publicado en 2017

Intestinal inflammation is coordinated by the metalloprotease ADAM17

Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer

artículo científico publicado en 2009

Involvement of Phospholipase D 1 and 2 in the subcellular localization and activity of formyl-peptide-receptors in the human colonic cell line HT29.

artículo científico publicado en 2009

Janus--a comprehensive tool investigating the two faces of transcription

artículo científico publicado en 2013

Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis

artículo científico publicado en 2021

Life-threatening chronic enteritis due to colonization of the small bowel with Stenotrophomonas maltophilia

artículo científico publicado en 2005

LifeTime and improving European healthcare through cell-based interceptive medicine

artículo científico publicado en 2020

Linear isoforms of the long noncoding RNA CDKN2B-AS1 regulate the c-myc-enhancer binding factor RBMS1

scientific article published on 14 August 2018

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

scientific article published on 26 November 2020

Low-Avidity CD4<sup>+</sup> T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19

scientific article published on 26 November 2020

MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells

artículo científico publicado en 2015

MIP-3α expression in macrophages is NOD dependent

artículo científico publicado en 2012

Massively parallel RNA sequencing identifies a complex immune gene repertoire in the lophotrochozoan Mytilus edulis

artículo científico publicado en 2012

Maternal epigenetic pathways control parental contributions to Arabidopsis early embryogenesis.

artículo científico publicado en 2011

Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Diseases

artículo científico publicado en 2019

Metastatic triple-negative breast cancer patient with TP53 tumor mutation experienced 11 months progression-free survival on bortezomib monotherapy without adverse events after ending standard treatments with grade 3 adverse events

artículo científico publicado en 2017

Method for preparing single-stranded DNA templates for Pyrosequencing using vector ligation and universal biotinylated primers.

artículo científico publicado en 2006

Microbial pattern recognition causes distinct functional micro-RNA signatures in primary human monocytes

artículo científico publicado en 2012

Microbiomarkers in inflammatory bowel diseases: caveats come with caviar

artículo científico publicado en 2017

Microbiome and nutrition. The way to a future therapy for chronic inflammatory bowel diseases?

artículo científico publicado en 2014

Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2

scientific article published on 01 February 2019

Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress

artículo científico publicado en 2013

Molecular signatures of a disturbed nasal barrier function in the primary tissue of Wegener's granulomatosis

artículo científico publicado en 2011

Molecular signatures of the three stem cell lineages in hydra and the emergence of stem cell function at the base of multicellularity

artículo científico publicado en 2012

Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB.

artículo científico publicado en 2017

Multigenerational Influences of the Fut2 Gene on the Dynamics of the Gut Microbiota in Mice

artículo científico publicado en 2017

Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine

artículo científico publicado en 2021

Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4.

artículo científico publicado en 2017

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer

scientific journal article

NOD-like receptors and human diseases.

artículo científico publicado en 2007

NOD-like receptors: ancient sentinels of the innate immune system.

artículo científico publicado en 2008

NOD-like receptors—phagolysosomal compartments and PAMP recognition

NOD2 influences trajectories of intestinal microbiota recovery after antibiotic perturbation

artículo científico publicado en 2020

NOD2-C2 - a novel NOD2 isoform activating NF-kappaB in a muramyl dipeptide-independent manner

artículo científico publicado en 2010

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.

artículo científico publicado en 2013

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition

artículo científico publicado en 2018

Neuroprotection with angiotensin receptor antagonists: a review of the evidence and potential mechanisms

artículo científico publicado en 2005

New susceptibility loci for severe COVID-19 by detailed GWAS analysis in European populations

artículo científico

Next-generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN-amplified neuroblastoma

artículo científico publicado en 2012

No association between the TUCAN (CARD8) Cys10Stop mutation and inflammatory bowel disease in a large retrospective German and a clinically well-characterized Norwegian sample.

artículo científico publicado en 2007

Nod2 is essential for temporal development of intestinal microbial communities.

artículo científico publicado en 2011

Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin

artículo científico publicado en 2016

Nucleotide divergence vs. gene expression differentiation: comparative transcriptome sequencing in natural isolates from the carrion crow and its hybrid zone with the hooded crow

artículo científico publicado en 2010

Nutritional Targeting of the Microbiome as Potential Therapy for Malnutrition and Chronic Inflammation

artículo científico publicado en 2020

Optic nerve regeneration after intravitreal peripheral nerve implants: trajectories of axons regrowing through the optic chiasm into the optic tracts

artículo científico publicado en 1999

Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model

artículo científico publicado en 2013

Oral immune priming with Bacillus thuringiensis induces a shift in the gene expression of Tribolium castaneum larvae

artículo científico publicado en 2017

Overlapping and unique signatures in the proteomic and transcriptomic responses of the nematode Caenorhabditis elegans toward pathogenic Bacillus thuringiensis.

artículo científico publicado en 2015

Paneth cells as a site of origin for intestinal inflammation.

artículo científico publicado en 2013

Phylogenetically widespread alternative splicing at unusual GYNGYN donors

artículo científico publicado en 2006

Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma

artículo científico publicado en 2011

Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles

scientific article published on 23 September 2019

Probiotics and Intestinal Diseases

artículo científico publicado en 2010

Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression

scientific article published on 09 November 2019

Pseudomonas aeruginosa populations in the cystic fibrosis lung lose susceptibility to newly applied β-lactams within 3 days

artículo científico publicado en 2019

Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3.

artículo científico publicado en 2018

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

artículo científico publicado en 2021

Publisher Correction: Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition

artículo científico publicado en 2018

RNA based individualized drug selection in breast cancer patients without patient-matched normal tissue

artículo científico publicado en 2018

RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition

artículo científico publicado en 2012

Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8

artículo científico publicado en 2022

Rapid response of stage IV colorectal cancer with APC/TP53/KRAS mutations to FOLFIRI and Bevacizumab combination chemotherapy: a case report of use of liquid biopsy

artículo científico publicado en 2020

Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection

artículo científico publicado en 2012

Recent transfer of an iron-regulated gene from the plastid to the nuclear genome in an oceanic diatom adapted to chronic iron limitation

artículo científico publicado en 2010

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

artículo científico publicado en 2012

Regulated proteolysis as an element of ER stress and autophagy: Implications for intestinal inflammation.

artículo científico publicado en 2017

Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion

artículo científico publicado en 2007

Regulation of polyp-to-jellyfish transition in Aurelia aurita.

artículo científico

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

artículo científico publicado en 2008

Reply

scientific article published on 15 February 2020

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artículo científico publicado en 2018

Role of ADAM17 and IL-6 transsignaling in inflammatory bowel disease

Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer

artículo científico publicado en 2017

Role of NOD2/CARD15 in coronary heart disease

artículo científico publicado en 2007

SNP discovery performance of two second-generation sequencing platforms in the NOD2 gene region

artículo científico publicado en 2010

SNPSplicer: systematic analysis of SNP-dependent splicing in genotyped cDNAs

artículo científico publicado en 2006

Salmonella enterica serovar Typhimurium ΔmsbB triggers exacerbated inflammation in Nod2 deficient mice.

artículo científico publicado en 2014

Sarcoidosis is associated with a truncating splice site mutation in BTNL2.

artículo científico publicado en 2005

Screening of human gene promoter activities using transfected-cell arrays

artículo científico publicado en 2010

Segregational Drift and the Interplay between Plasmid Copy Number and Evolvability.

artículo científico publicado en 2019

Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model*

article

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

artículo científico publicado en 2008

Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing

scientific article published on 12 September 2016

Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut

scholarly article

Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-beta1.

artículo científico publicado en 2004

Species-specific viromes in the ancestral holobiont Hydra

artículo científico publicado en 2014

Specific immune priming in the invasive ctenophore Mnemiopsis leidyi ⬇️

artículo científico publicado en 2013

Stage IV Colorectal Cancer Patients with High Risk Mutation Profiles Survived 16 Months Longer with Individualized Therapies

scientific article published on 08 February 2020

Stem cells and aging from a quasi-immortal point of view

artículo científico

Stories of love and hate: innate immunity and host-microbe crosstalk in the intestine

artículo científico

Swarm Learning for decentralized and confidential clinical machine learning

artículo científico publicado en 2021

Systematic association mapping identifies NELL1 as a novel IBD disease gene

artículo científico publicado en 2007

Systematic evaluation of the effect of common SNPs on pre-mRNA splicing.

artículo científico publicado en 2009

Systematic expression profiling of innate immune genes defines a complex pattern of immunosenescence in peripheral and intestinal leukocytes

article

Systems Medicine in Chronic Inflammatory Diseases

artículo científico publicado en 2018

TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants

artículo científico publicado en 2009

TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.

artículo científico publicado en 2003

TNF-α and IFN-γ regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells

article

Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans

artículo científico publicado en 2017

TassDB2 - A comprehensive database of subtle alternative splicing events

artículo científico publicado en 2010

TassDB: a database of alternative tandem splice sites

artículo científico publicado en 2007

Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways

scientific article published on 22 July 2019

Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes

scientific article published on 27 March 2019

The Dark Age(ing) of the Inflammasome.

artículo científico publicado en 2017

The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models.

artículo científico publicado en 2009

The Inducible Response of the Nematode Caenorhabditis elegans to Members of Its Natural Microbiota Across Development and Adult Life

scientific article published on 07 August 2019

The JNK inhibitor XG-102 protects against TNBS-induced colitis

artículo científico publicado en 2012

The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression

artículo científico publicado en 2004

The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice

artículo científico publicado en 2019

The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma

artículo científico publicado en 2015

The Transcriptome Analysis and Comparison Explorer--T-ACE: a platform-independent, graphical tool to process large RNAseq datasets of non-model organisms

artículo científico publicado en 2012

The angiotensin II type 2 (AT2) receptor promotes axonal regeneration in the optic nerve of adult rats

artículo científico publicado en 1998

The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany.

artículo científico publicado en 2018

The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease

scientific article published on 10 December 2010

The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.

artículo científico publicado en 2018

The expression of the beta-defensins hBD-2 and hBD-3 is differentially regulated by NF-kappaB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis

artículo científico publicado en 2009

The genomic basis of Red Queen dynamics during rapid reciprocal host-pathogen coevolution

article published in the Proceedings of the National Academy of Sciences of the United States of America

The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.

artículo científico publicado en 2013

The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus

The native microbiome of the nematode Caenorhabditis elegans: gateway to a new host-microbiome model

artículo científico publicado en 2016

The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses

artículo científico publicado en 2010

The resilience of the intestinal microbiota influences health and disease

artículo científico publicado en 2017

Toll-like receptor-induced granulocyte-macrophage colony-stimulating factor secretion is impaired in Crohn's disease by nucleotide oligomerization domain 2-dependent and -independent pathways

artículo científico publicado en 2008

Toward the blood-borne miRNome of human diseases.

artículo científico publicado en 2011

Towards a molecular risk map--recent advances on the etiology of inflammatory bowel disease

artículo científico publicado en 2009

Transcriptome and genome sequencing uncovers functional variation in humans

artículo científico publicado en 2013

Transcriptomic resilience to global warming in the seagrass Zostera marina, a marine foundation species

artículo científico publicado en 2011

Transgenic and infectious animal models of HIV-associated nephropathy

artículo científico publicado en 2009

Transglutaminase-catalyzed covalent multimerization of Camelidae anti-human TNF single domain antibodies improves neutralizing activity.

artículo científico publicado en 2009

Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution

artículo científico publicado en 2012

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease.

artículo científico publicado en 2016

Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence

artículo científico publicado en 2008

Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease

artículo científico publicado en 2018

When the most potent combination of antibiotics selects for the greatest bacterial load: the smile-frown transition

artículo científico publicado en 2013

Whole genome and exome sequencing of monozygotic twins discordant for Crohn's disease.

artículo científico publicado en 2014

Widespread disruption of host transcription termination in HSV-1 infection.

artículo científico publicado en 2015

XIAP variants in male Crohn's disease.

artículo científico publicado en 2014

aFold - using polynomial uncertainty modelling for differential gene expression estimation from RNA sequencing data

scientific article published on 10 May 2019

c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells.

artículo científico publicado en 2014

mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease.

artículo científico publicado en 2012

p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease

artículo científico publicado en 2002

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico

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